Basic Information

Insect: Brachyptera putata
Gene Symbol: hb
Assembly: GCA_907164805.1
Location: OU015472.1:11749102-11752383[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.097 8.6 8.0 0.1 2 23 266 287 265 287 0.96

2 8 1.3 1.1e+02 4.5 0.4 1 23 290 313 290 313 0.91

3 8 0.039 3.5 9.2 0.7 1 23 353 375 353 375 0.97

4 8 0.004 0.35 12.3 2.3 2 23 383 404 382 404 0.96

5 8 0.00017 0.015 16.6 4.5 1 23 410 432 410 432 0.99

6 8 0.024 2.2 9.9 5.2 1 23 438 462 438 462 0.93

7 8 0.0011 0.1 14.0 0.6 1 23 716 738 716 738 0.96

8 8 0.11 9.4 7.8 0.4 1 22 744 765 744 768 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.097	8.6	8.0	0.1	2	23	266	287	265	287	0.96
2	8	1.3	1.1e+02	4.5	0.4	1	23	290	313	290	313	0.91
3	8	0.039	3.5	9.2	0.7	1	23	353	375	353	375	0.97
4	8	0.004	0.35	12.3	2.3	2	23	383	404	382	404	0.96
5	8	0.00017	0.015	16.6	4.5	1	23	410	432	410	432	0.99
6	8	0.024	2.2	9.9	5.2	1	23	438	462	438	462	0.93
7	8	0.0011	0.1	14.0	0.6	1	23	716	738	716	738	0.96
8	8	0.11	9.4	7.8	0.4	1	22	744	765	744	768	0.89

Sequence Information

Coding Sequence: ATGAACAACCCCGTGTGCGCCATGCCCGCTATGTTACGTCATGCCGGCCAGTCATTGGTCAGTTATGACGTAATCCCATGTAACGACGCGCCTACGTGGCATCACAGTCCTGTGCAGTCACAAGTGAAGCAAGAATCTCTCGATCAAGACCACCACAGCCCCATCAACGACTCCGGAATCTCTCCGGGCCACGGTTCCTCGTCGGATCCGTCCCCCGGCTCGCAGTCCTCCCACATCTCTCCTCGCACCACCCCTCCGGCCCCGGGCTACCTCTCCCCGAACCACCCGACGAACCTCTCCCCGATTCCGGACGCAATCCAGCCGAGAAACGTCTCGCCTCGTTGCATCGCTCAGAACCTCATCCCAAGCACTGTCAACGGGATCTCCCGGATTAACTCTCCGAACCACGTTCTCAACGTGCCTTCGCGCAACCAGTTCAATCCGTACAACGCAACCAACGGATCCCCGCATTACAACGTTAACTCCCCCGCGATGGGAATCACGCCGCAGGGTCGTTTGAACGCCCCGATTTCCCCCGTCGAACTCAGGATCGGATCGCCGATGGGACGTGGAGAAGGACCGAGGAGGATTCTGTTGACGACTCCGACCGCGCAAGAGGAGGGACACTCGTCATCATCGTCGGATGCCGAGGGGTATTACAACGCCAAGATGGCCGCCGTTCCCGAGTCGCACGGACGAGAGGATCCACTGAGAGGACTGCAGATGGCGTTGGAGAGGACTGGGATGCTGGGCGCTGCTAAGGAAGCGGAAAGCGAGCCGGTGATTCAAGTCCTGCAGTGTCCGCTGTGTACATTCGTTGCTAATTCACGGCCAAGCTTCAACGCTCACCTCGGCACGCACTACGAGCACAAGTGCACGATGTGCGACTTCACAGCCCAGGGCGTGGACGTGCTGCGCGCCCACCTGCGCGACTCGCACGACCAGCTCCTCTCGCCCGATACGGACGTCGACGCCAACGAAGCGGAGGGTTCGCTGGAGGGCGACGAGCCGGGCGTGCGAATCCCCCGCGTCAACTCGCAGGGCAAGGTCAAGACGTTCCGCTGCAAGCAGTGCGAGTACGTCACCGTCACTAAGCTCGACTTCTGGGAGCATTCGCGCGGTCACATCAAGGCCGAGAAGCTACTCATCTGCCCCAAGTGCCCGTTCGTCACGGAATACAAACACCACCTCGAATATCATCTCCGGAACCATTTCGGTTCGAAGCCGTTCAAGTGCGATAAGTGTAGTTATTCGTGCGTCAACAAGTCGATGTTGAACTCTCATCTGAAGTCTCACTCGAATGTTTACCAGTACCGTTGCGCCGATTGTAATTACGCGACAAAGTATTGCCACAGTTTGAAGTTGCATCTGCGAAAGTACGAACATAAACCCGCGATGGTGCTCAACGCGGACGGTTCCCCGAACCCGTTGCCGATCATCGACGTTTACGGCACGCGACGCGGTCCCAAGCTGAAACCGAAAGAAGACGACGCTCCGCCGACGATGGTCCCGAATCAGTATACGATGTTCCAGACTCCGTTTGTGATGCACCAGAACCAGATGCTACCGTTCCCGTACGGACCGATGAATCCGATGATGAATCCTTATCACAGTAACGCGTCGTTCCCGGCTTTCCCCCGTCACCAGATCCCGGAGAAGAACCTCGAGGAAGCTAACATGGAACGTATCATGAGTTTCGTTAATAATAACATCAACAATAACGCTACCGAAGGTTTGAAGGATTACATGGCCAAGGTGATCAACACGGAAATGACCCAAGAAACCAACGACGAAGAAGTCAAAGACGAGGAAGAGATTCCCGCCGGCACTCCGTTGGATCTGAGCAAGGCCGACGACGTTCCCGTTAGCAGCGTTCCCGCCGGTAACAAGAACCGTCGCAAGGGCAAGGCGTTCAAGCTGGAACGTCTTGCGATGCTGACGCAGCACAATTCTGAGGACGACGACGAAACGTATCCAGCGAGGAAGGTCGCGAAAATCGACGAAGGTTACGACAACGTGATGACCCCCCGTTCGATTAACATCCCCACAGAGATGAAGGTTGTCGCGGAGCAGAAGGCAGTCGCGGAGACCGAGAAAGAAGTGGAAAACATCGAGGTTGTAAAGGATAAAGTCGCGCCGGAGGTGTACAACTGTACGTACTGCGACATCACGTTCCGGGATATCGTGATGTACACGATGCACATGGGATATCACGGGTATCAGGACCCGTTCAAGTGCAACATGTGCGGCCAGCTGACGGCCGATAAAGTGTCTTTCTTCCTGCACGTCGCTCGCACGTCGCACTGTTGA
Protein Sequence: MNNPVCAMPAMLRHAGQSLVSYDVIPCNDAPTWHHSPVQSQVKQESLDQDHHSPINDSGISPGHGSSSDPSPGSQSSHISPRTTPPAPGYLSPNHPTNLSPIPDAIQPRNVSPRCIAQNLIPSTVNGISRINSPNHVLNVPSRNQFNPYNATNGSPHYNVNSPAMGITPQGRLNAPISPVELRIGSPMGRGEGPRRILLTTPTAQEEGHSSSSSDAEGYYNAKMAAVPESHGREDPLRGLQMALERTGMLGAAKEAESEPVIQVLQCPLCTFVANSRPSFNAHLGTHYEHKCTMCDFTAQGVDVLRAHLRDSHDQLLSPDTDVDANEAEGSLEGDEPGVRIPRVNSQGKVKTFRCKQCEYVTVTKLDFWEHSRGHIKAEKLLICPKCPFVTEYKHHLEYHLRNHFGSKPFKCDKCSYSCVNKSMLNSHLKSHSNVYQYRCADCNYATKYCHSLKLHLRKYEHKPAMVLNADGSPNPLPIIDVYGTRRGPKLKPKEDDAPPTMVPNQYTMFQTPFVMHQNQMLPFPYGPMNPMMNPYHSNASFPAFPRHQIPEKNLEEANMERIMSFVNNNINNNATEGLKDYMAKVINTEMTQETNDEEVKDEEEIPAGTPLDLSKADDVPVSSVPAGNKNRRKGKAFKLERLAMLTQHNSEDDDETYPARKVAKIDEGYDNVMTPRSINIPTEMKVVAEQKAVAETEKEVENIEVVKDKVAPEVYNCTYCDITFRDIVMYTMHMGYHGYQDPFKCNMCGQLTADKVSFFLHVARTSHC

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00243755;
90% Identity: iTF_00243755;
80% Identity: -