Basic Information

Insect: Brachynemurus nebulosus
Gene Symbol: zfh1
Assembly: GCA_035578155.1
Location: JAPWDM010000003.1:66983757-66995108[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.058 3.2 9.8 0.9 2 23 16 38 15 38 0.91

2 8 0.034 1.9 10.5 0.8 1 23 114 136 114 136 0.96

3 8 7.9e-05 0.0043 18.8 0.6 3 23 141 161 139 161 0.96

4 8 3.3e-05 0.0018 20.0 6.5 1 23 170 192 170 192 0.99

5 8 0.00028 0.015 17.1 1.0 1 21 198 218 198 219 0.95

6 8 4.8e-05 0.0026 19.5 0.7 1 23 613 635 613 635 0.94

7 8 0.00046 0.025 16.4 9.9 1 23 641 663 641 663 0.98

8 8 0.0063 0.34 12.8 3.5 1 21 669 689 669 690 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.058	3.2	9.8	0.9	2	23	16	38	15	38	0.91
2	8	0.034	1.9	10.5	0.8	1	23	114	136	114	136	0.96
3	8	7.9e-05	0.0043	18.8	0.6	3	23	141	161	139	161	0.96
4	8	3.3e-05	0.0018	20.0	6.5	1	23	170	192	170	192	0.99
5	8	0.00028	0.015	17.1	1.0	1	21	198	218	198	219	0.95
6	8	4.8e-05	0.0026	19.5	0.7	1	23	613	635	613	635	0.94
7	8	0.00046	0.025	16.4	9.9	1	23	641	663	641	663	0.98
8	8	0.0063	0.34	12.8	3.5	1	21	669	689	669	690	0.96

Sequence Information

Coding Sequence: ATGCCACCAAAAGACGACATCCTAATCGGTCAACAATACTTtatgaaatgtcaaaaatgtcaaCGTGGTTTCGCATCATTTCAACAGTTCAAAGAGCATGTCGATTTAGAACACCCCCATCTATTTATTGAAGATACGCCTATGACCAATATAACTGCCGGGACCGGGACGCTTGAGAATCATATGACACCACCACCGATGGTGATGACACCACTTTCATCGTCACATAAATCGGATATTTCATCGCCGACACCTTCATCAGTGGGtacaactaataataataataataatgatcaGATGGCGTCACCAGGTTCGGTTACTTCGTTAGGGAATAGTGTGTTCAGTTGTAGTCAATGTTCGATGTTATTCCCGTCCAAGGAACAGTTGGATAAGCATGAAACGTCGCATCCTCAagtgAATTGCAAAGTATGTCAGAAAACTTTTGCCAATGTCTATCGTCTTCAACGGCACATGATCAGTCACAACGAGAGCGCGTTGTTACGAAAATTCAAATGTACGCAGTGTGAGAAAGCGTTTAAATTCAAACACCATCTGAAAGAACACATACGGATACATAGCGGCGAAAAACCATTCGAATGTGTCAATTGTGGAAAACGATTTTCACATTCTGGTTCATACTCGAGTCATATGACTTcgaaaaaatgtttaacaaaCCCAAAATTGGTACGAACAAAATCAGCCAATAGCTCACCACCGAATCCggccgtacaaaaattggaatcaccgattaaacaaaatttactaGAAAATTCGAATTTAAATCAATCGTATAATTCATTTCTCGCGATGTCACCGGTACGTTCGTACAATGAACGCACAATTGCCGCCTTTTTGGCGTCCATGCGCAACAATCACATCCCAACAATTTCCCCCCTCTACCATTTCCCGCTTTCGCCACCTCATTTCTCGGAACAGAGAAACGAATATATTGATGATAGTAAATCGGTTAAATCGGACGAAAAAGAAGTGGATTACAATATCGATGTGGAAAAAGTGGACGAAAATATGGAAGAGAAAACTGAGGATCCAAATGTTTCGAATGATTTCGAAACGgttaagaaaattttggaaaCTGTAAACATGAAAATGACCACACAATTACTAGGTGCTAGAAAATTATCAGTGTCCTCGGGTAGTTCTGTCGGTCAATCAGAACCATCCGAAGGACTGGCTGCCAAATTGGAAGAATGTTTACCGTCTGAAAAATATGAAACATCGGAAAATGATCATTCCGTGGACGATTTCGACGACACAAGTTCGGTGGGCGATGAACGAAAAGTTCGCGTTCGATCTCTTATCGGTGAAGATCAATTGGCAATCTTGAAAGAGTACTACCTTAACAATTGTCGTCCAAGCCGTAAGGAATTAGAACAAATTGCCAACCATATTGGATTCCCAATTCGCGTCGTACAAGTTTGGTTCCAGAATACGCGAGCACGTGATCGACGCGAAGAACGATATCTGTCCGCGTATCAAAATATACCTAGAGCGCATGTGCGAACTTATTCAGACATGTACTCACCCGAACCAAGTGATGAACCGTTGGATCTGtcagttaaaaaatttcgtaaaagcgATGATTACGAGGAAGCGGTCAATTTAAGTCAAAAATCATCTCGAAACATTGAAAATAccgaaaattttcattataatccCTATACAATATCGTCGGAAACTCGAATTCAGTCACCGACCATGAAGAAAATCGGTTCTTCGCCAATGTATTTAAAAACTATCACAAATCACACGGAAATACAAAATAATGGCTCAAAATTTCGAACGGATTTGACAATTAAAGCAGAAATGGAAGAACAATTCGTTTGCGACCAGTGTAATAAAGCGTTTGCCAAACAGAGTTCGTTAGCGCGCCATAAATATGAACATTCAGgtCAACGTCCATACAAATGTGATAAATGTACAAAAGCTTTCAAACATAAACACCATTTGACAGAACACAAACGACTTCACAGCGGCGAGAAGCCATTTCAGTGTGGCAAATGTTTAAAACGATTCTCACATTCAGGCTCATACAGTCAACACATGAATCATCGATACTCCTACTGTAAACCCTATCGGGAATAA
Protein Sequence: MPPKDDILIGQQYFMKCQKCQRGFASFQQFKEHVDLEHPHLFIEDTPMTNITAGTGTLENHMTPPPMVMTPLSSSHKSDISSPTPSSVGTTNNNNNNDQMASPGSVTSLGNSVFSCSQCSMLFPSKEQLDKHETSHPQVNCKVCQKTFANVYRLQRHMISHNESALLRKFKCTQCEKAFKFKHHLKEHIRIHSGEKPFECVNCGKRFSHSGSYSSHMTSKKCLTNPKLVRTKSANSSPPNPAVQKLESPIKQNLLENSNLNQSYNSFLAMSPVRSYNERTIAAFLASMRNNHIPTISPLYHFPLSPPHFSEQRNEYIDDSKSVKSDEKEVDYNIDVEKVDENMEEKTEDPNVSNDFETVKKILETVNMKMTTQLLGARKLSVSSGSSVGQSEPSEGLAAKLEECLPSEKYETSENDHSVDDFDDTSSVGDERKVRVRSLIGEDQLAILKEYYLNNCRPSRKELEQIANHIGFPIRVVQVWFQNTRARDRREERYLSAYQNIPRAHVRTYSDMYSPEPSDEPLDLSVKKFRKSDDYEEAVNLSQKSSRNIENTENFHYNPYTISSETRIQSPTMKKIGSSPMYLKTITNHTEIQNNGSKFRTDLTIKAEMEEQFVCDQCNKAFAKQSSLARHKYEHSGQRPYKCDKCTKAFKHKHHLTEHKRLHSGEKPFQCGKCLKRFSHSGSYSQHMNHRYSYCKPYRE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00238596;
90% Identity: iTF_00238596;
80% Identity: iTF_00238596;