Basic Information

Gene Symbol
HIVEP1
Assembly
GCA_035578155.1
Location
JAPWDM010000009.1:24219778-24233986[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 8 0.00025 0.014 17.2 1.4 1 23 240 262 240 262 0.98
2 8 0.032 1.7 10.6 5.3 1 21 268 288 268 292 0.89
3 8 0.016 0.89 11.5 0.9 1 21 509 529 509 530 0.95
4 8 1.5e-05 0.00081 21.1 2.1 1 23 1307 1329 1307 1329 0.99
5 8 1.4e-05 0.00076 21.2 4.7 1 23 1335 1359 1335 1359 0.92
6 8 8.9e-05 0.0048 18.6 1.5 2 23 1926 1947 1925 1947 0.97
7 8 0.0011 0.062 15.1 2.3 1 23 1955 1979 1955 1979 0.92
8 8 0.0035 0.19 13.6 3.0 1 23 1997 2021 1997 2021 0.93

Sequence Information

Coding Sequence
ATGGAAAACTCAATCAGCACTTCAAAATATCTTCATAAGAAGTTCAAGAAATCTGCACCGACAATTATTGAAACAAACGTACCAGTAACTCCAAGTGCTCAAACCATCGAAGTAAAGTCCGCGTCGCCGTCTCACGACTCCAATAGTACCACTAATGGCCTAGCAACAACGACAACACTAGTGACAAATGAAATTGCAACAGTCAATAAAAAAAGTGACAGTGTTGTTATTGAACAggacataaataaaaatagtgttGTAGCAAgtacaaataatataaatagtgttaataatattaatgacCAAGTGGCTTCCATATCAACGAGCTCGTCAGTACCTTTCACCACATCATCCGACACCTCCACACGAGTAGTTTCTAAATTGCAGTCTTCCTCACATTTGACAACCACTAATGATAAGTTACAAATAGTGGACCGTGAAAATAGTAtttataatattcataataGAAATCTAGAACCAAACTTTCACGACATATCAGATAAAACTGACCACCACCATAGTGAATCGTTACAGAGTGGCATCCCGGCAAGACGGGAATTGTCTTCCATACTAAATCACACCACTGGTACATCAGTTACCACCAGTAATCACCCAACCAACACCACCCAAAACATTTCAACCGCCAGACCAACCGTCGTCACACTAGACACTGACAAAAAACCGCCCGCGCCAAACGAAACAACACAAGGCGGCAAATACGTGTGTTCCTATTGCAACCTCTCCTGTTCCAAACCGAGCGTGCTCCAAAAACACATTCGAGCACACACCAATGAACGACCATACCCCTGCTACAGTTGCGGATTCAGTTTCAAAACGCGATCCAACCTCTACAAACATTGTCGATCAAGATCTCACGCAAATCGTACAAAAGACTCGCCCGAAATCACCTTAAATCAACAACAGACGATGCCCCCACAGCATACTGTCATCAAACCTCCCCTAGTAGATCAAACATCCACAACCTCCACAATAATGGAAATCAAACAACAAGAACACCCCAATAACGACTACAAATTAACAAACAGTGAGAATATCCCAAAATCGAAACCGTACAAACCGAAATTCCGACATTCACTCTATACGTATGAGCAAAACACACCCGATAACGATAACAACAACGAAAACAAGGAGAAAGACCAAAGCGcggaaaagaaaaaattcgaaaGTCAGACGCAAATCACCGCCAAACCACTTTCGAGCGATTTGAAACAGAACACTGATCTCTTGAAACAGCACATCAACAATTTGATCCACAAAAATCAAACGATCTTAGATGTGCACGAGCCAAACGCGTTCAAAAAACGGCTCTTCTATCAACAATTGGATAGTGATGAAAATCGACTACATCCAAGAAATTTTTATGACTCAAACACCAATCTGTCGCACGATGAACCGTTAAATTTAACCGCGCGAAATCGTAAGCGATGCATGAGTGAAACGGAACATAGTCAAAAAAGTCTAATCAAGGAACTCCTGCTAAAAAATTTAACGCAAGAACAAAGTTACGTTTGCCAATTTTGTAAAATCTCCttcaaaaatatcgaaaattttgaaatacatcggaaaaaatattgtaaagttGGCGAAAATCCCACATCAAAAGATATCGCGCTAGTACGAAGTCATTCAGTGAACGTGGCATCAGTATTAACCCAAAAATATTCACGAAACAATGAGAGCCCATCAAAATTTGTACGGACCACATTACCGCTAAAATCCCCGGGACCATATTTAGGTAAAACTAGTTTAATCGGCGATAAACCGAATCAAGTATTCTATGAGAATCGAAATCCAACAAAAATTCATCATGCTGCCGCTCTTTCAATTTCCTCGGAtaatttacgaaaaatttacGATAAAAATGATATCTTGTATAATCCGTTAAAATTAAACGACAGTGTCAAACCACCCCAAGATACCGGGCCAGAAAGAAAATCGAGTTTTGACGAATTTCAAATGACTTACAGTCCCACAGCCAAAAAAACGCATACACCCATCAAACTCTTTGGCGGCGAAGTGAAAATAACAGAGACATCTGGCGAAACAAGAAGTTAcaaaattgattcaaaaaaCGCCAGTGAATTGTCCCCAAACTCGCAACAGTATGGCGTCACGTACGGGTGCAAAGTTAGCGAAAATATGGTCATAAAATCATCTCTACAATCAGGTGCGACCATATTACAAAACAGTGCCAATTATGACCCAAAAGCGTTACCGCTCACCCCAAAACTTGATGAAAAGTCGCCATTTATGCCCCTACAATTTCAgtatgacaccaaaatgcaagAAAACACGCCCGTACTAAGAAAAATACCATACGAACCAAAAGACCCATCAAAATTTTCTCCCGCGGTGTCAGAAAGCATCTACGATCAAcgaaattttattgattttcgaTCAAAATCCGCCAACATGTTTGCACCCACAATCAAACCGCCAGACCTCACGATACCTGGCATACCAGTACCGAATAAAGTGTACACATCGCCGAAGAAAATTTACACTGACGGCACGGAACCACAAATATCCCCAAGCTGGTCAAATCTAAATAGTCCAATTATTGATTCTAGTAAATATTTACCAAACGTTCGATATCGGCAAGAGCCAAGATTTCAACCACTCAGTCCCAGCATGTCTCCAAAAACGGAAATCAGAAGTTCACGGGAAAGTCCGAAGTTACGTAATGATCTCTACTCAACAATACCTGTAAATAATAGCATAATCAGAATCAACCATGAACCCGAAAAACCGGAAGTAAACAACCCCCCTAGTGTGAATCCCGACCTAAAATTATACGACCCTTTAAACATACTGATCAACGGAAAGTTGGTCCGTTACGTGCCCGGAATGCCAGGTCCTGAAACGGGGAATCCGATTCACGTAGGTTTCATAGAGTCGTCACCAATTGTAGCCACGCAACAATCCCCAAAAATCATCCGAACATTTCCCGATACAAATAGATCTGTCGAcgacattttaaaaatcgaaCCATCAGCAAAAATTATCCAGCATTCATCAGTGTCCCCGCGAAATCATCTAACACCTTCCCCAAACGTCGTCAAGTTATCGCCAATCAGCGAAAGGCCGACTCATCTAAGTCCCAATGTTATTCAACACACAGCCGAAAATTTGAGTCCCAGACACAGTCCAATCACGCCGgaaaaaaagtcaaatgatCAAAAGACTTCGTTAAAAAACTTTCGCATTTATGTAGATAACTCCGTTAAAACcgtcaaaaatattgaaaaaaacgaAGATAGCAAAAATCAAGAAAAGCCGAACACTCCTCCCAACAGAAGTACTCCAAATGAAATCATAACATCAAAAAATTCCACCTCTGAAAGTTCAGACCCAAAACCAGATTCAAACGAACCTAAATCAACcaacaataataaatttcttcGGCCAAACAGTTTGGCCATAAAACCATACATCAAAACTCATCATGGCTTAACGCCCACAATTTTTAATCAAGCCCTAATTAGCCCGGACACGCCTCGCATAGCcaaaaaatattgtcaactcTACTTGAATGGCAATTGCTTCAGTTATTTGGGCCTGAAAAGTTCCACAAAATCCACTTATTGTACACTGAACAAAACCCAGCCATTTTACGTGCAAAGTTTCGGCACGTTGAGTATGTACTCAGAATGGAGACATTTGGAATGTAAATTGGATTACGTGAGACTGGACACTTACGACTCAAGACAGCGAAAAAGCTCCTATACGGTGGCCCGACATAAAATCCCGGATTTAATTGTAGATTCTAGTTATAAGTCTGTGGTGGTTGAAAGTTCACAAAAGAAAGAAGATAGTACAAATCGTGGTAATTTGTTACCCGGAGGATACGAATCAAACGAAGAATATACCTACATCAGAGGACGAGGACGCGGAAAGTACGTTTGCGATCAGTGTGGGATTCGATGCAAGAAGCCATCGATGCTCAAAAAGCACATACGAACGCATTCAGATGTCCGACCGTACACCTGTCAGCATTGCAATTTCAGTTTCAAAACAAAGGGTAACCTAACGAAACACATGAAAAGCAAGGCACATTACAAAAGGACCAACAGTGTATCCACAAGTGACGTAAACGGGGAAATACAAACGTCACAGTGCAGTAGTACGCCCTCTGATGATGACACCGAAAGCGACGGGGAGAATGAAAATGACAGTGacgaTTCGACAAGATTGCAAGATCACGAAGCCGCTCACTGTTTACTTTCATTATCGCAAAATCGATCTCCAGCTTCCACAGAATCCGAAAATATTGACGCCAATCGAGAAATCAGTAATAATACTCCAACATCATCAACAGCCACTGACGACATGACGTCTGAAATGTCAAGCATGGACTCAAAGAAAGATTCCGATGACAAATTCAATAAAACTTCTACCTCAGCCACTTCTAGCAACTCATCTTCGAACGTTTTCGAGACAATGTCCACACGGAAACCGTTAACCTACCCCTACTATAAAGTACAAGTGAAACCCGTCACTCCAATTGAACCAAAAccggaaatattaaaaattgacgTCGCGTCAAATTTCAATAGCGTCATACTTGGTGCCAAAAATGTCGAACTGTTTAGTCAAAATTCCCGCGAAATATTCTCGCCCAATGTTACAACACcgacaaaaattcaatttattggCGATAAACTTCCAAATGCTGATCTAGCAATTGCCAATTACCAACAGAAATTCGTTAAATACGAACAAGAAAGGGCCTTGTTGAATCAAACCAAAAATGAAGAGATTCGACGCCAAAATCCAGATACATTACCCACATTTATAATATCCAATGACCGTAAACGATCATTGTCCAGTGTTGATAAGGCATTCGATTTTGAATACTCAAAACGAAAAGTATCGTCGCAAGATGTCGTGCCAGAACCCCAACCGCCTCAGCAACAAATTCGAAAACGGCACATATCCGTTGATTTAACTTCCACAAACAGTCCCACGACTGTCAACAACTTCAACAACATCCGAAAACGTAAAGTGTCGTATCCAGAAGTGCGGGAACCCCCGGAAATTCGCACCGCCCCAGAATTCAACACGTACGAAAACAATGTCACCGTAATCAACACGAACACAAAACCCTACAACAATATTCAACCCCGTGGTGTCGATTTAATCGTCAATCGCGATTTCGTCGAGAATCGAAACGCTTCAGCAAGAATTGAAAATCCACCAGCCGCACTGGATCTGtcaaaaatgtcgaaaaaaGACACTACTACAACCCCCACTCCCAATATAATCCCACCCCAAAAATACATAATCATCGACAAACCCACGCCAGAAATTAAAATTCCCACAACAAAACCAAATTTAGAATTAAATCCCGACCTAAAAATGGTGATCAAACGAAAAGTACTCGTGgacaaactgaaaaattttcaaacggaAAAACCCGTCGATGACACCCCAAATGAAACACCTCAAACAAATGGTGATGTGATCGTGACAAATGAAATCACAACCACCCCCACCCCCAGTGTCGAAAAAACACCACCTGCACCGGATCAGAACGATACATCCGCCATGCAAACGTTGGCCGAAATAGCTATGAAACGGGTGTCGACAGAGAACACGAAACTGGCACAGAGTGTTGCAacggaatatttaaaattggcCACGAAAAATGAAACGCAACCTGGTGTGATTATTGAACCGGCGCCACCAGCCGCGTGTAATGGAACCACGGAAACGAATATATCCGATTTGATTATTAAATCGGAGGAGAATAAAAGTTGTACAATGTGTGcgaaaaatttcagtaaacCATCGCAATTaagattacaTATGAATACTCACTACATTCAACCATTTCGGCCATTTCGTTGTGAATCGTGTTCTGTCAGTTTCCGATCAAAAGGACATCTACAGAAACATGAACGAAGTGCTAATCATCATAACAAATTATCCTCGTCACCAACAACTAGTTCATCCGAGCCTCGTCCATTCAAATGTTCCGATTGTAATATAGCGTTTCGAATCCACGGCCATCTAGCGAAACATTTACGAAGTAAAACGCACATAATGCGTTTAGAGTGTTTAGCACGCGTTCCTTTTGGACTATATGCCGAACTCGAGCGAGCAAATAGTCTACTAACTGAAATCAACACCACAGACTGTGATATGTGCCTTGAAAGCTTAAAGaTTCTTGCACGAAAATTATTTAGTAACGATCCAAATAAATTAGCGCAAATGGAAAATCCGTCGACAAGTTTATCGTCGAATCAACAACCAGAACAGCAACAAATCGCTGTTGGGAGTCCGTGA
Protein Sequence
MENSISTSKYLHKKFKKSAPTIIETNVPVTPSAQTIEVKSASPSHDSNSTTNGLATTTTLVTNEIATVNKKSDSVVIEQDINKNSVVASTNNINSVNNINDQVASISTSSSVPFTTSSDTSTRVVSKLQSSSHLTTTNDKLQIVDRENSIYNIHNRNLEPNFHDISDKTDHHHSESLQSGIPARRELSSILNHTTGTSVTTSNHPTNTTQNISTARPTVVTLDTDKKPPAPNETTQGGKYVCSYCNLSCSKPSVLQKHIRAHTNERPYPCYSCGFSFKTRSNLYKHCRSRSHANRTKDSPEITLNQQQTMPPQHTVIKPPLVDQTSTTSTIMEIKQQEHPNNDYKLTNSENIPKSKPYKPKFRHSLYTYEQNTPDNDNNNENKEKDQSAEKKKFESQTQITAKPLSSDLKQNTDLLKQHINNLIHKNQTILDVHEPNAFKKRLFYQQLDSDENRLHPRNFYDSNTNLSHDEPLNLTARNRKRCMSETEHSQKSLIKELLLKNLTQEQSYVCQFCKISFKNIENFEIHRKKYCKVGENPTSKDIALVRSHSVNVASVLTQKYSRNNESPSKFVRTTLPLKSPGPYLGKTSLIGDKPNQVFYENRNPTKIHHAAALSISSDNLRKIYDKNDILYNPLKLNDSVKPPQDTGPERKSSFDEFQMTYSPTAKKTHTPIKLFGGEVKITETSGETRSYKIDSKNASELSPNSQQYGVTYGCKVSENMVIKSSLQSGATILQNSANYDPKALPLTPKLDEKSPFMPLQFQYDTKMQENTPVLRKIPYEPKDPSKFSPAVSESIYDQRNFIDFRSKSANMFAPTIKPPDLTIPGIPVPNKVYTSPKKIYTDGTEPQISPSWSNLNSPIIDSSKYLPNVRYRQEPRFQPLSPSMSPKTEIRSSRESPKLRNDLYSTIPVNNSIIRINHEPEKPEVNNPPSVNPDLKLYDPLNILINGKLVRYVPGMPGPETGNPIHVGFIESSPIVATQQSPKIIRTFPDTNRSVDDILKIEPSAKIIQHSSVSPRNHLTPSPNVVKLSPISERPTHLSPNVIQHTAENLSPRHSPITPEKKSNDQKTSLKNFRIYVDNSVKTVKNIEKNEDSKNQEKPNTPPNRSTPNEIITSKNSTSESSDPKPDSNEPKSTNNNKFLRPNSLAIKPYIKTHHGLTPTIFNQALISPDTPRIAKKYCQLYLNGNCFSYLGLKSSTKSTYCTLNKTQPFYVQSFGTLSMYSEWRHLECKLDYVRLDTYDSRQRKSSYTVARHKIPDLIVDSSYKSVVVESSQKKEDSTNRGNLLPGGYESNEEYTYIRGRGRGKYVCDQCGIRCKKPSMLKKHIRTHSDVRPYTCQHCNFSFKTKGNLTKHMKSKAHYKRTNSVSTSDVNGEIQTSQCSSTPSDDDTESDGENENDSDDSTRLQDHEAAHCLLSLSQNRSPASTESENIDANREISNNTPTSSTATDDMTSEMSSMDSKKDSDDKFNKTSTSATSSNSSSNVFETMSTRKPLTYPYYKVQVKPVTPIEPKPEILKIDVASNFNSVILGAKNVELFSQNSREIFSPNVTTPTKIQFIGDKLPNADLAIANYQQKFVKYEQERALLNQTKNEEIRRQNPDTLPTFIISNDRKRSLSSVDKAFDFEYSKRKVSSQDVVPEPQPPQQQIRKRHISVDLTSTNSPTTVNNFNNIRKRKVSYPEVREPPEIRTAPEFNTYENNVTVINTNTKPYNNIQPRGVDLIVNRDFVENRNASARIENPPAALDLSKMSKKDTTTTPTPNIIPPQKYIIIDKPTPEIKIPTTKPNLELNPDLKMVIKRKVLVDKLKNFQTEKPVDDTPNETPQTNGDVIVTNEITTTPTPSVEKTPPAPDQNDTSAMQTLAEIAMKRVSTENTKLAQSVATEYLKLATKNETQPGVIIEPAPPAACNGTTETNISDLIIKSEENKSCTMCAKNFSKPSQLRLHMNTHYIQPFRPFRCESCSVSFRSKGHLQKHERSANHHNKLSSSPTTSSSEPRPFKCSDCNIAFRIHGHLAKHLRSKTHIMRLECLARVPFGLYAELERANSLLTEINTTDCDMCLESLKILARKLFSNDPNKLAQMENPSTSLSSNQQPEQQQIAVGSP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-