Basic Information

Gene Symbol
-
Assembly
GCA_035578155.1
Location
JAPWDM010000006.1:42189936-42219720[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 0.32 17 7.5 4.8 1 21 526 546 526 547 0.94
2 12 0.0026 0.14 14.1 2.0 1 21 575 595 575 596 0.94
3 12 0.00015 0.0084 17.9 0.3 1 21 619 639 619 640 0.96
4 12 0.0014 0.077 14.9 3.1 1 21 649 669 649 670 0.94
5 12 0.0018 0.097 14.5 0.2 1 21 801 821 801 822 0.96
6 12 0.0021 0.11 14.3 3.0 1 21 830 850 830 851 0.93
7 12 0.0025 0.14 14.1 0.3 1 21 857 877 857 878 0.96
8 12 0.0041 0.22 13.4 0.8 1 20 886 905 886 907 0.96
9 12 4 2.2e+02 4.0 1.2 1 14 922 935 922 936 0.85
10 12 0.031 1.7 10.6 2.0 1 21 940 960 940 961 0.95
11 12 0.043 2.3 10.2 0.7 1 20 969 988 969 990 0.96
12 12 3.6e-07 1.9e-05 26.2 1.1 1 21 1005 1025 1005 1026 0.96

Sequence Information

Coding Sequence
ATGGTTCGTAGACGAACTGCAGGAAATGAAACTAATATCGATCAGTTACTTATGAACTGGGGCTTTGATGAATTAATTCCAGTTTTTCGAGaaaatggtATCGATTTAAGTGGACTGCATTTATTAGATGGTGACACACTAAAAGAATTAATACCTAAAGTTGGACCACgtgttaaatttcaaaataaattaaaagattatcaactaattaaaaatattaatatgttattttcgaATGAAATTCAACCGGCCGACATAGTTCCTGATTCAAATACACAAACTTCACTACCTACGGATAATGTTGAGCCTGAGCCATCCACCGCGGAACCGGTCACTAAGAAACTAAAAACTAGTAATTACAATTATTTGTTGACGCTTGATATAAAAAAGATTCTTTTAGAATCCTGTAACGGTCAAATTATCCTAAATCACTATGAAAAAAATCGTATATTAGACAGTAAAATGAGGAATTTACTAACTGAGATAGTTATTGGACATATTATGGCAAATTGTAATCGacGTCTAGCTTCAGCCGACTTTGAAATATTGGCCGCACaaatatgtcaaatatttaaaaatgaaaatatcgaAACTTACTTTCTTGCCCCTCTTAGAAAGAGTGAGTCACCTCTACAGAAATCGGAACCGGCCCGAGGAAAGCTTGTCGATAAGTATCGTAATAAACTTAGAGCACTTAAATCACTAGATGCTGATgggaaattgaaatttaaaaacactGCGGAGTCCAGCTCTATTATTCAAGTGTCTAACAgtagTATGGAAGCAATCAGTTGGTTAAAAGTTAATATTAAACCCTGGCATGAATTAATACATAAATGGAATTTATCATATGACTATCGTAAAAGTATCAAAACAAAATGTTCGTTTGAGTCTTTTATGGATTTGTGGCCATGTCTTACTATACAGGAAGGTTATAATCTTATTGATGAAGACTTCAGAGCTGAATTTGGTGCAAATGCTTCAGATATGTTATTTAGAAAATGGGACACCTTTTTCGATAAATTACTTAAGTCTTCTAATGTAGTGTCTTCGTTTGCGGATCAATTGATGAATCTAAGAATTTTGGGCGGAAatGCAAAATATGCAACACAGTTGTCAATGCTTGGCTATTTATTTCCACCGCGAAGCCGAGCTCGACTGCAAAAAAAAGGAAACTGTTGGAAGCCAACTAAGAAAGATTCTTCAGAGGAAATCATCATACAAGTTAATTCACTGGCTGAAGTTAGCAGTATTTATCGAAGCAAGCAAGAAAGATACCAACAATTTGATTTGCCAATTTATTATCCGTTTATCGTTATTTTAGGCAGTTTTGAAAATGTTCAAgaaatttatgttaatattgGTGATAAACTGTTGTATAACATTCCCTCGGTACTGAAAGCTTTAGATATTTGTTTCAAAAgctttcatgtattaaatatgacaTACCCAATAGCAACAGAACATATATGGTCTTTATTAGAACTAGCAGTATATGAGATTGATGTCCCGAATCATCGTAAAATCCCTCATGTAATCGGAAAGCTATCAGATTTAAAAtGTCCAGATGGTCGCTTTTATTGTGATAAATGTTACCGTTCATACGGCCATAAAACAAGTTTATATAAACACAAGAAATACGAGTGCGGTAAAGAGCCAATGTTTACATGTGTCTATTGTTATCACAAGTCGcatataaaatcaaatttaaaaaaGGTGAGGCACTATTGTCCCGATTGTGGAAAATCATATAAATTTAAACAAGGCTTATACGAACATCGTAAATTCAaatgtggtaaagaaccaacaTTTAAATGCCCGTATTGTCCGAAACTTTGTGCACCCGTTAACAGATATAAATGTCCCGACTGTGACAAATCATATGTATTTAAACAAGGATTGATTGCGCATCGCAAATATAAATGTGGCGATAAGGAGCCATTATTTGCGTGTACATATTGCCCAAAACGTTGTTTTCAAAAAGCACATTTACAAACGCACATGCTATCTTTTTTATCATCTTCTTACTATTCACCATACGCCAAAGCATCGTCTTCGTCGTCAAATGAAATACCGggaattgttatttataatccaacagatggtgctgaaagtattttatatttagatgAAAACAGCATTGATCCAAATGATGATTTAGGGGTGATTGAAATCAAAGACGAACTCAAAATCGTATTTCCATTAAAGTATCCATATGAATTGGATGAGATGGAGAGGAATATTAAACTTGATCATGACTACAAACAACAACTAtttaaaaaaatgattgaaATTGGCGGTGTTAACGACGATGCGTGCAAAACACTTCGTGCAATTGCGTACAGGATGTTTTCAACTGAACTCTTGTTAAATTTTACGTGGTCAGattttacaAAAAGATATATCTGTCCGGATTGTGGAAATTCATATAAATTTAAGAAAGGTTTACTAGCACATCGTCGATACACCTGTGGTAAAGAGCCACAATTTGCATGCCCGTACTGTCCAAGAAGATGTCATCAGAAGGGAAATTTACGAAAGCACTTATTTACCTGTGACAAGCCAGCATATGAATGCCCAAAATGTGGAAGTTTTTATAGATCACAAGGAGCACTTTATTCTCATCTTAGATATAAATGTGGCAAACCGCCACAATTTAAATGCCCTTTTTGCCCGAAACAGTGTTATATCAAGGGCAATTTACAAAAGCACATTGTAATTTGTCGATTTAATCCAAATTGTTTAACTGAAGATCAGTATAAATATCAATGCACATATTGTTCAAAACGATCTCATGATAAAAGTGCGGAGCCAAGATATGAATGTTTAAAATGTGGGAATTGTTATAAATCACAAGGAGCACTTTATTCACATCGTAAATATAATTGTGGCCAAAAGCCACAATTTAAATGCCCTTTTTGCCCAAAATTGTGTTTTATCAAGGGCAATTTAACAAAACACATTGTAATTTGTCGATCTAATCCAAATTGTTTAACAGAAGATCAATATAAGTATCAATGTACATATTGTCCAAAACGGTTTTATAATAAGAGTAATTTGCAACAGCATATGATGGTTTGTAAAATGAATCCGGTTCGATAA
Protein Sequence
MVRRRTAGNETNIDQLLMNWGFDELIPVFRENGIDLSGLHLLDGDTLKELIPKVGPRVKFQNKLKDYQLIKNINMLFSNEIQPADIVPDSNTQTSLPTDNVEPEPSTAEPVTKKLKTSNYNYLLTLDIKKILLESCNGQIILNHYEKNRILDSKMRNLLTEIVIGHIMANCNRRLASADFEILAAQICQIFKNENIETYFLAPLRKSESPLQKSEPARGKLVDKYRNKLRALKSLDADGKLKFKNTAESSSIIQVSNSSMEAISWLKVNIKPWHELIHKWNLSYDYRKSIKTKCSFESFMDLWPCLTIQEGYNLIDEDFRAEFGANASDMLFRKWDTFFDKLLKSSNVVSSFADQLMNLRILGGNAKYATQLSMLGYLFPPRSRARLQKKGNCWKPTKKDSSEEIIIQVNSLAEVSSIYRSKQERYQQFDLPIYYPFIVILGSFENVQEIYVNIGDKLLYNIPSVLKALDICFKSFHVLNMTYPIATEHIWSLLELAVYEIDVPNHRKIPHVIGKLSDLKCPDGRFYCDKCYRSYGHKTSLYKHKKYECGKEPMFTCVYCYHKSHIKSNLKKVRHYCPDCGKSYKFKQGLYEHRKFKCGKEPTFKCPYCPKLCAPVNRYKCPDCDKSYVFKQGLIAHRKYKCGDKEPLFACTYCPKRCFQKAHLQTHMLSFLSSSYYSPYAKASSSSSNEIPGIVIYNPTDGAESILYLDENSIDPNDDLGVIEIKDELKIVFPLKYPYELDEMERNIKLDHDYKQQLFKKMIEIGGVNDDACKTLRAIAYRMFSTELLLNFTWSDFTKRYICPDCGNSYKFKKGLLAHRRYTCGKEPQFACPYCPRRCHQKGNLRKHLFTCDKPAYECPKCGSFYRSQGALYSHLRYKCGKPPQFKCPFCPKQCYIKGNLQKHIVICRFNPNCLTEDQYKYQCTYCSKRSHDKSAEPRYECLKCGNCYKSQGALYSHRKYNCGQKPQFKCPFCPKLCFIKGNLTKHIVICRSNPNCLTEDQYKYQCTYCPKRFYNKSNLQQHMMVCKMNPVR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-