Bneb014259.1
Basic Information
- Insect
- Brachynemurus nebulosus
- Gene Symbol
- ZFY
- Assembly
- GCA_035578155.1
- Location
- JAPWDM010000003.1:48210696-48212096[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 10 0.058 3.2 9.8 3.1 1 23 160 183 160 183 0.89 2 10 6.5 3.6e+02 3.3 5.7 2 23 189 210 188 210 0.92 3 10 0.00014 0.0075 18.0 0.2 2 23 216 237 215 237 0.97 4 10 0.00011 0.0058 18.4 3.8 1 23 243 266 243 266 0.98 5 10 0.02 1.1 11.3 2.4 2 23 275 295 274 295 0.97 6 10 7.2e-05 0.0039 18.9 2.0 3 23 303 324 301 324 0.94 7 10 5.3e-05 0.0029 19.4 0.2 3 23 332 352 331 352 0.99 8 10 1.5e-05 0.0008 21.1 0.2 1 23 358 381 358 381 0.97 9 10 0.00084 0.046 15.6 1.3 1 23 387 409 387 409 0.98 10 10 0.0016 0.084 14.7 3.9 1 23 415 438 415 438 0.96
Sequence Information
- Coding Sequence
- ATGTTTAAAGAATGTGCTTCAGTAGAtATATCCGAAGATGACGAACTACCTCCTCaaatttgtcaaatttgttttacaCGGTTACAagattcatttaattttaaaactatgtgtcaaaaatcgaattATGATTTGAGGCGAGTAATTgctgaacataaaaaaaataaacccaACGAAGGTTTAGTACAAGACTGTGACGAGAAACCAATCTTGttaaaaaatgaagtttttagTATAGATGACGAATTAAAAGATTTCAATTTGGAAACGTTGTCAATTAAATCTGAAAATTTATCTGCAGGTGACCAAATAGAAAACAATTATAATGATGAAACGCTTTCGTTAAAAAATGAAGAGTGTCGTACAGATGACgagaaaaataatgaaaatattcaaGATGAAAAAGCTAGTTTActggaaaaaattcaaatcaatacAAACATGAAAACCAAAACACGaacaaaacataaaaaagaatttatatgTGAAAAATGTGAAAGAAAATTTGACACGCCTTGGCATCTTGGCTGGCATTGTAAAAGTACTCATAAAGCGACAGGAACAAAATGTAGTTATTGTGATGTAATATGTTATCATTCAgaacatttaaaatttcacgaagaatcaCATTCAATTTTGACTATTAAATGTGAAGATTGTGGCAAGGAATTTGCTAGTAAGATCTTTTTCGCTAGCCATATTTACACTCATAAAACTGATCGGCCATTCAAGTGTCAACAGTGCGATTCCGCGTTTAAGACTAAAtgtagtttaaaaattcacatgaAAGTGATGCATACATTCGACCATAGAAGGCTCTCAACGTGTCACATATGTAACAAGACCGTTAAGTATGATAACATGAAACTACACCTTAGAGTTCACGCTGAACGTAATCCACTTGATTGTTCAAAGtgtggaaaaaaatttgttacaaataacTCATTGAGAACTCACTTCAGACTATTTCACGAAAATGGCACCCAAAATTTGTGTAGCGTTTGTGGCTACGGAACTAAAACGGAAGCGGACCTCGTGAGACACATGCGCACACACACGGGTGAGAAACCATACCAATGTGATAAATGTGAGAAGAGGTATCCAAGGGCAGATGCATTAAAAATCCATGTTCGGAACGTGCATTTAAATGAACGGAAACATGTGTGTTCAATTTGTTCGGAGGCCTTTCACGTGAAAGCAGTACTCGAGAATCATATGCGTAGACACACTGGTGAACGGCCATTTGCATGTTTTGTTTGTGGTAAAACGTTTTGCGCTAAAGTTTCAATGCAACATCACCTGAAACGAGTGCATAAGGcggaaaatctaaaaaaatag
- Protein Sequence
- MFKECASVDISEDDELPPQICQICFTRLQDSFNFKTMCQKSNYDLRRVIAEHKKNKPNEGLVQDCDEKPILLKNEVFSIDDELKDFNLETLSIKSENLSAGDQIENNYNDETLSLKNEECRTDDEKNNENIQDEKASLLEKIQINTNMKTKTRTKHKKEFICEKCERKFDTPWHLGWHCKSTHKATGTKCSYCDVICYHSEHLKFHEESHSILTIKCEDCGKEFASKIFFASHIYTHKTDRPFKCQQCDSAFKTKCSLKIHMKVMHTFDHRRLSTCHICNKTVKYDNMKLHLRVHAERNPLDCSKCGKKFVTNNSLRTHFRLFHENGTQNLCSVCGYGTKTEADLVRHMRTHTGEKPYQCDKCEKRYPRADALKIHVRNVHLNERKHVCSICSEAFHVKAVLENHMRRHTGERPFACFVCGKTFCAKVSMQHHLKRVHKAENLKK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -