Basic Information

Insect: Brachynemurus nebulosus
Gene Symbol: zfh1
Assembly: GCA_035578155.1
Location: JAPWDM010000008.1:22056190-22061817[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.0036 0.2 13.6 3.2 2 23 323 345 322 345 0.91

2 8 0.00071 0.039 15.8 3.7 1 23 373 395 373 395 0.99

3 8 4.6e-05 0.0025 19.5 0.3 1 23 401 424 401 424 0.96

4 8 4.1e-05 0.0022 19.7 0.2 1 23 430 452 430 452 0.98

5 8 2.7e-06 0.00015 23.4 0.5 1 23 458 480 458 480 0.98

6 8 0.00037 0.02 16.7 1.0 1 23 486 508 486 508 0.97

7 8 7.6e-06 0.00042 22.0 1.5 1 23 514 536 514 536 0.98

8 8 1.8e-05 0.00098 20.8 1.9 1 23 542 565 542 565 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.0036	0.2	13.6	3.2	2	23	323	345	322	345	0.91
2	8	0.00071	0.039	15.8	3.7	1	23	373	395	373	395	0.99
3	8	4.6e-05	0.0025	19.5	0.3	1	23	401	424	401	424	0.96
4	8	4.1e-05	0.0022	19.7	0.2	1	23	430	452	430	452	0.98
5	8	2.7e-06	0.00015	23.4	0.5	1	23	458	480	458	480	0.98
6	8	0.00037	0.02	16.7	1.0	1	23	486	508	486	508	0.97
7	8	7.6e-06	0.00042	22.0	1.5	1	23	514	536	514	536	0.98
8	8	1.8e-05	0.00098	20.8	1.9	1	23	542	565	542	565	0.95

Sequence Information

Coding Sequence: atggaacaaACGTATTCAATTGAAATCATACAGCCGTCAGATTTGGAAAATTTGGCGTCATCCGATAATGTAATTGAATTGACCGATATTGGAATTATTGGTTTAGATTCGTTGTGTCGAATATGTGCAAGTCGTAGCGATAATTTAATACCAATTTATGAAGGTGAAGGTTTGGAATATCAATTAGAGATGAAAATCAATCGACATTTTCCATTTACCGTGGAGAAAAATGATGCATTACCAACGCATTGTTGTTACCAGTGTGCGAGTACGTTGTTGACATGGCATGAATTAGTAGAAACAAGTATTGAAGCCGACAAACGGTTAAAAGCATTACAATTTGAAACGGTTGTTCAGTTAAATCAAaaattcgaaaatttagATGAAAATAATGAATCTATAGTGGAACCAGAAGAGACGGCTGTTAACATTATCGTTCCCACCACTGTTGAACCAagGCTCGCGCAGTCCCGAGCAGCCGAACATGTAACAATTCGCCAAGCTCAGTCCAACAATTTTACCGTTGACTATTTACGTGAAAGTTGCAAGACGAAAATTAAAGATGACGTGTCTGACGATGCTAATGATGGTGACGTAAAATCGGATAACTTTATTATCGAttgtaaaaaattcaaagaTCATCATTCGGATGATGAGTTAAGCGTAAAAACTAGTTTTGATTATTTAGAAGGTGATGATGTTGATGATAAACCGAAACTAGAAGAGTCAGTGGCGGATATCAAGAACGAATTTAGTGATACAACTAGcgaaattagtttaaaaaatagtgttttaacgaaaaaattgatCACTGATCGTAAGAGTAAACGTTTAAAACGGCACATTTTGAAACCGAAACATATTAATCAGTTGAGTACGGTGGAACGTGTTAAATTAGAGATCGACAGCGATCTAATCAAATTCGAATTGAAAGAAGAAATCGATTTAGATCGAGACAAAACGTGTATGTGCATGTATTGCGGTGTACGATTCACCAATCGGAAACAACTGCAAGAGCACAAGTTGCTCAAACACGAGAACGACAAATTGTGTCGCACCAAATTGAACAAGGAAGATATTGAGCATGCGCAAGTGATCATCGATAAACGCACCTACTACCAGTGTCACGAATGCGGTAAAAATTTACACAGCCCGTACACCTATATGTGGCATCGTCGCATCCATACCGGCGAGCGACCGTTCGTGTGCGACCTGTGCGGCAAACAGTTCCGTGTCTCGCAGGGCCTGGTGCGTCATTTGCGTGAAACGCATGCCGGCATCAAAAATTTCCCGTGCGATCTGTGCGGACGAATGTTTGCGTCACGGCGCAACGTCGAGGAGCATCGTCGCATTCACACGAACGAGCGTCCGTACGTGTGCGATCTGTGCGGTAAAGCGTTCAAACAGAAGGCGTCACTGTTCGTACATAATCGGTCACATTCGGATATATTCCCGCATAAATGTTCGTACTGTGGACAGGGGTTTCGTACGAGGGCGCCACTGTTGGTGCACGTGACACGGCACACGGGCGAAAAACCGTATCCGTGCGATGTGTGCGGACGATGTTTTCGCATTAAGTACGAATTGAATCGACACCGTTTGATACACTCCGACGAGAAACCGTTCAGTTGCACGGACTGTGGCATCTCGTTTCGACAGAAGCGCTATTTACGCAATCATAATAAAATCAATCATAGTGATCGACAAATTGTGCCTTCATCGTCGTAG
Protein Sequence: MEQTYSIEIIQPSDLENLASSDNVIELTDIGIIGLDSLCRICASRSDNLIPIYEGEGLEYQLEMKINRHFPFTVEKNDALPTHCCYQCASTLLTWHELVETSIEADKRLKALQFETVVQLNQKFENLDENNESIVEPEETAVNIIVPTTVEPRLAQSRAAEHVTIRQAQSNNFTVDYLRESCKTKIKDDVSDDANDGDVKSDNFIIDCKKFKDHHSDDELSVKTSFDYLEGDDVDDKPKLEESVADIKNEFSDTTSEISLKNSVLTKKLITDRKSKRLKRHILKPKHINQLSTVERVKLEIDSDLIKFELKEEIDLDRDKTCMCMYCGVRFTNRKQLQEHKLLKHENDKLCRTKLNKEDIEHAQVIIDKRTYYQCHECGKNLHSPYTYMWHRRIHTGERPFVCDLCGKQFRVSQGLVRHLRETHAGIKNFPCDLCGRMFASRRNVEEHRRIHTNERPYVCDLCGKAFKQKASLFVHNRSHSDIFPHKCSYCGQGFRTRAPLLVHVTRHTGEKPYPCDVCGRCFRIKYELNRHRLIHSDEKPFSCTDCGISFRQKRYLRNHNKINHSDRQIVPSSS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -