Basic Information

Gene Symbol
-
Assembly
GCA_035578155.1
Location
JAPWDM010000005.1:54227885-54232821[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 9 0.00053 0.029 16.2 2.4 2 23 186 208 185 208 0.94
2 9 5.4 3e+02 3.6 3.5 2 11 228 237 227 249 0.79
3 9 0.0001 0.0055 18.5 1.7 1 23 265 287 265 287 0.94
4 9 4.2e-05 0.0023 19.7 0.5 1 23 300 322 300 322 0.98
5 9 1.7e-06 9.4e-05 24.0 0.6 1 23 327 349 327 349 0.99
6 9 0.00015 0.0084 17.9 0.2 1 19 355 373 355 377 0.93
7 9 0.0001 0.0055 18.5 9.6 1 23 383 405 383 405 0.97
8 9 1.2e-08 6.5e-07 30.8 0.3 1 23 411 433 411 433 0.98
9 9 1.8e-06 9.9e-05 24.0 0.9 1 23 439 461 439 461 0.98

Sequence Information

Coding Sequence
ATGGAAATTTTTCCAGAAAATCAGAACACCGATACGGAACATAATATTGCAGAAATGTTAAAAGCTATTGTTAATTTGGAGccaaAACCAGATGATAAATTGCCACAACATATCTGTACAAAATGTTACCTGAAATTATCATCTGCGTACGATTTCAAAAAGCAATGTGAGAAAGTCAACACAAAATTACAGTCGCTAGCTGATAGTGAATTTGTACCTGTTGTGATTGAAAGTATTATCCCACTCGACGATGATGATGAAGAGGATGAAAATCACGAAAACGATGAAGATTTACCGACAATTAAACAAGAACAGGACACGAGATCAGACGGGGAAGAAGAGGGCCACGAATATTACGATTATATTGTGCCAGATAGCCACAATTCAGATGATTTGAatgatttcaaatttcaaacgaTTGAAGTTATCAATAATGATGAGGTTGAAGAAGgtaCCATCATACAAATTCTGTCACCAAGCCAATTGAACGAACACATCGCCGAGGATTACGACGACGAACTAAACGACACCAACGAATCTTCAGAACAACCATGCATGTGTCAGCTGTGTGGCAGAATATTCAATTATCGTGAAAATTTAGCGAAACACTTCCGACTTCAACATCCCGACGAGGAACCGGCGGAAGACGAGACATTTACCGACGACAAATCAAATTTAGTTTCATGTAACAAATGTGGCGAGAGTTTTACGTGTGCCCAACAGTGTCGTGATCACAAATTGGACCACGTGCTAGAAAGTCGCATAGAAATCAGCGAAAATGGTGATATTATACACATTTGTAACATATGCGGCCGAACTTTCCCTAGCAAACACGGTTTAAGTATACATCAAGCGTTTCACACGAACCGGAAACTGGACGTGGACGTGGAAAAACCATACGCATGTCCAGTGTGCGACAAAATGTTTGTCACGATGAAGGCGATGCGAAATCACAAGAAAACTCATGGAAACAAAACATAcgtgtgtaatatatgtaataaaacgTTTACAATCAAAGCCCGATTACAGATTCATATTCGAACACACACTGGCGAGAAACCGTATTCGTGCCCGGACTGTGGAAAACGTTTTGGAAACACTACATCGTTGCGTATCCACGATCTAATACATTCCGGGGCGCGGCCACACTACTGTAAAATCTGTAATCGACGATTTAAACAACATAGCCATCTGAAAAATCATCTGTTGACTCACAGCGGTCTAAGACCATTCGAATGTCCGGTTTGTGGGAAAACGTTTGTATTTAAAGGCAATCTAACGGTTCATATGCGTATGCATTCGGGAGAAACACCGTATATTTGTCCGGTGTGTGGAAAAGGATTTTACGATTCGAGTCGAATGAAGAAACATCGTAGAACTCACGATAAGAATTATCCGTGTAATACAACTCCTGTTactagtaaataa
Protein Sequence
MEIFPENQNTDTEHNIAEMLKAIVNLEPKPDDKLPQHICTKCYLKLSSAYDFKKQCEKVNTKLQSLADSEFVPVVIESIIPLDDDDEEDENHENDEDLPTIKQEQDTRSDGEEEGHEYYDYIVPDSHNSDDLNDFKFQTIEVINNDEVEEGTIIQILSPSQLNEHIAEDYDDELNDTNESSEQPCMCQLCGRIFNYRENLAKHFRLQHPDEEPAEDETFTDDKSNLVSCNKCGESFTCAQQCRDHKLDHVLESRIEISENGDIIHICNICGRTFPSKHGLSIHQAFHTNRKLDVDVEKPYACPVCDKMFVTMKAMRNHKKTHGNKTYVCNICNKTFTIKARLQIHIRTHTGEKPYSCPDCGKRFGNTTSLRIHDLIHSGARPHYCKICNRRFKQHSHLKNHLLTHSGLRPFECPVCGKTFVFKGNLTVHMRMHSGETPYICPVCGKGFYDSSRMKKHRRTHDKNYPCNTTPVTSK

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-