Basic Information

Gene Symbol
-
Assembly
GCA_035578155.1
Location
JAPWDM010000026.1:452555-456758[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 11 0.0015 0.083 14.8 4.1 1 23 226 248 226 248 0.97
2 11 0.00013 0.0069 18.2 1.3 1 23 254 276 254 276 0.98
3 11 0.00032 0.018 16.9 2.1 1 23 282 305 282 305 0.96
4 11 0.1 5.5 9.0 3.7 1 21 311 331 311 333 0.95
5 11 0.00047 0.026 16.4 1.9 1 23 339 361 339 361 0.99
6 11 0.00045 0.025 16.4 0.3 1 23 367 389 367 389 0.98
7 11 0.0022 0.12 14.3 0.8 1 23 397 420 397 420 0.97
8 11 0.00013 0.0072 18.1 2.5 2 23 427 448 426 448 0.97
9 11 0.00064 0.035 15.9 0.3 1 23 454 476 454 476 0.98
10 11 1.9e-06 0.00011 23.9 2.2 1 23 482 505 482 505 0.97
11 11 2.6e-06 0.00014 23.5 0.8 1 23 519 541 519 541 0.97

Sequence Information

Coding Sequence
ATGGCTACCGAATTTGGCCAGATTAAAATTGAGGGGTTGGATAGTGAATCTGGTGAAAATGTGACAGAAATACAATCCTATTTGGATACATTCAACAAAGAAATTCAAAGTGCAGATGGGACAACCATCACCCAGTTGAcagAAGTTGAAAAAGAAGACGGTGACGATGACGATGGAACCTATTTCGTGGATCAAGCTGGACGCTATTATTATCAAGCGAAATCGGGCAGTCAACAAGTGCTAGCGATACGTCAGTCATCGGCAGAAAATGGCGACGAGGATGGCGAAGATGGTGAGGGTGGTTCAGCCAATGAAGAAGGTGAAACCACCGAATTTTTAATACAACGCGAAGATGTGGAAGATGATGAAGAGGGTACCATCATAAATGACGCCGAATCGAATCAAATGTTAATAAATTCCGGCGATGCCTTCCAAACAGTAACCATTGTACCTTCAGAAACTAGTCCCGGTGAAGTGAGTTACGTACTAATCGTGCAACAACCTGACGAGGAAGATCAAAAAATGAACGACCAAACGCCCGGCGATCAATCCAATTTAAACGTGtacgattttgatgaaaatgaAGAAGGTGGCATGGTGGACTCGGACGCCGAAGACGAcaaatcaaaaattatcaaattagtCCCCAGGAAATCACAGACAGTCACACAGGCACACATGTGTAACTATTGTAACTACACTAGTCCAAAACGGTACTTGTTGTCGCGACATATGAAGAGTCACTCGGAGGAGCGGCCGCATAAATGTAGCGTTTGTGAACGCGGTTTTAAAACCATTGCGTCACTGCAGAACCACGTGAATACACACACTGGCACCAAACCGCACCGATGTAAATACTGTGAATCGGCGTTCACCACGTCCGGCGAACTGGTACGTCACGTACGCTATCGACACACGCACGAAAAACCACATAAATGTCGAGAATGCGATTACGCAAGCGTCGAACTAAGTAAATTGAAACGGCACATACGTTGTCACACCGGAGAACGACCGTATCAGTGCCCCCACTGCACCTACGCCAGTCCCGACACGTTCAAACTGAAACGCCATCTCAGAATTCATACCGGGGAAAAACCGTACGAATGTGATATATGTCTGGCTCGATTCACCCAATCCAATTCCCTGAAAGCCCACAAATTAATTCACAACGTCGCAAATCGACCGGTATTCCCGTGCGAACTATGCCCCACGACATGCGGACGTAAAACCGATTTACGGATACACGTACAAAAACTTCATACTTCGGATCGTCCCCTGAAATGCAAACGATGCGGGAAATCTTTCCCCGATCGTTACAGTTACAAATTACACAACAAAACCCACGAAGgtgaaaaatgtttcaaatgtGACCTTTGCCCGTACGCCTCAATTTCGGCACGCCATCTAGAATCGCATATGTTAATTCACACCGACCAAAAACCGTATCAGTGCGATCAGTGTGGTCAATCGTTTCGACAGAAACAACTCTTGAAACGCCACCAAAACCTCTACCACAATCCAAATTATGTGCCACCAGCGCCGCGAGAGAAGACGCACGAATGCCCGGAATGTGCGCGTGCGTTTAGACACAAAGGTAACCTGATTCGACATATGGCTGTGCATGATCCTGAATCGAGTTTGCAAGAAACGCAACTTGCACTCAAATTGGGACGACAAAAGAAGATACAGATCATTGACGGACAACAGGTGGAAGTGATGCCGGGCGTCGACAGCGATATGGACGAAGATGAGACAGACGTGGAGGTGTCGACCGTTGAAAGTGCCGATGGACAACAGTACGTTGTCCTGGAAGTGATCCAGTTTGGCGATGACGAGGACGGAGATGGAAATAATGCTACTTTACTGGATGCAGGACAAATTATGCCCGATGGAGAACTAAATGAAGAAGATGTGCTAGCAGCACTGCAAGGACCTCGAGTAGAAAAGGAAGAGCATAACGAGGATGAGAAGAAGTTCAGCACAGAAAAGGATATGGAGACATGTTTTGGTTTCGATgaaGAAGATGGAGAACAGGAAGAAATAGAATCAAAAACGAATATGATTTTAGGCGGTCCTGCTAGTGACGATGAACATGATGGATCGTAA
Protein Sequence
MATEFGQIKIEGLDSESGENVTEIQSYLDTFNKEIQSADGTTITQLTEVEKEDGDDDDGTYFVDQAGRYYYQAKSGSQQVLAIRQSSAENGDEDGEDGEGGSANEEGETTEFLIQREDVEDDEEGTIINDAESNQMLINSGDAFQTVTIVPSETSPGEVSYVLIVQQPDEEDQKMNDQTPGDQSNLNVYDFDENEEGGMVDSDAEDDKSKIIKLVPRKSQTVTQAHMCNYCNYTSPKRYLLSRHMKSHSEERPHKCSVCERGFKTIASLQNHVNTHTGTKPHRCKYCESAFTTSGELVRHVRYRHTHEKPHKCRECDYASVELSKLKRHIRCHTGERPYQCPHCTYASPDTFKLKRHLRIHTGEKPYECDICLARFTQSNSLKAHKLIHNVANRPVFPCELCPTTCGRKTDLRIHVQKLHTSDRPLKCKRCGKSFPDRYSYKLHNKTHEGEKCFKCDLCPYASISARHLESHMLIHTDQKPYQCDQCGQSFRQKQLLKRHQNLYHNPNYVPPAPREKTHECPECARAFRHKGNLIRHMAVHDPESSLQETQLALKLGRQKKIQIIDGQQVEVMPGVDSDMDEDETDVEVSTVESADGQQYVVLEVIQFGDDEDGDGNNATLLDAGQIMPDGELNEEDVLAALQGPRVEKEEHNEDEKKFSTEKDMETCFGFDEEDGEQEEIESKTNMILGGPASDDEHDGS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00333106; iTF_01061057;
90% Identity
-
80% Identity
-