Bneb008855.1
Basic Information
- Insect
- Brachynemurus nebulosus
- Gene Symbol
- Rreb1
- Assembly
- GCA_035578155.1
- Location
- JAPWDM010000001.1:184888235-184890127[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 0.013 0.72 11.8 2.1 1 23 144 166 144 166 0.98 2 13 0.00048 0.026 16.3 2.4 1 23 171 193 171 193 0.97 3 13 0.0049 0.27 13.2 0.8 1 23 199 221 199 221 0.97 4 13 0.0028 0.15 13.9 0.2 1 23 227 249 227 249 0.97 5 13 1 54 5.9 0.2 3 23 257 276 256 276 0.91 6 13 0.00053 0.029 16.2 0.4 1 20 282 301 282 303 0.92 7 13 0.0069 0.38 12.7 6.5 1 23 318 341 318 341 0.96 8 13 1.4e-05 0.00074 21.2 2.8 1 23 359 381 359 381 0.98 9 13 0.00033 0.018 16.9 0.9 2 23 388 410 387 410 0.96 10 13 1.1e-05 0.00057 21.6 0.5 1 23 416 438 416 438 0.98 11 13 0.021 1.1 11.2 6.4 1 23 444 466 444 466 0.98 12 13 3.1e-05 0.0017 20.1 4.4 1 23 472 494 472 494 0.99 13 13 8.5e-06 0.00046 21.8 1.4 1 23 500 522 500 522 0.99
Sequence Information
- Coding Sequence
- ATGAAAAGCAAATTTCAGAGTAAAACATACGCTGAAATGATAATGGCGTGCACTTCTTTAAAGATAACAGAAACAGATGAGATTTCGCTAAAAATTTGCCTTGTTTGCACAAATCAAATTGATCAATCCTACATTTTCTATCAAAAATGTCATGAAGCCGACTTTATTTTACAGTttagttacaaattttataagaaGTCCCAAAATGAAGGTGACATTCAACAGTTGGCAAACGAACCAGCAGATAAAAGcgatgaaaattttaaagaagaagaaattgaagatGAAAGTAACGATTTACTCTCGAGCGATTTTGATTGCGCGCGGTCTCTGTCTTCAGACATTCTACTCAAAGAGGAAACTCAAATCGATCAAccatccaaaaataaaattaaaactagatCAAATGAAAACGACGATATCAAAATTTTCCAGTGTCATATCTGTTTAAAATCGTGGatttccaaattatttttacaaaaacacaTGCAAGTCCATTCAAAACAAATTCATAAATGCGATATATGCAGtctaacattttcaaattttatatcgCTAAAACGACACAAAATTGTTCATCTCGACACAAAACAATACATTTGTAACATCTGTAATTTAAATTTGCCCACTACTGTACATCTGACACGTCACAAAATCATGCATAAAAATCGACGAAAATTTATCTGTGACGAATGCGGTctaattttatcgaaaaataatctCTTAACGCAACATAAATTAACGCATCGCGGGGATATGCGACGTGTCTGCGAAATCTGTGGTTCCGATATCTCGCTACGAAATTTTCAACGGCACATGTACATTCATAACGCCCATAAACCACACAATTGTGGCCGCTGTGGCCGAGGATTCACGCAAAAACCCGAACTCACCCGACATAAATTGGTGTGCACGGGCGAATGGCGGACACCAAACGACACCAAAAAACTCTATCAGTGCACAATCTGTTTAAAAACGTACAAAAGTAATCACACACTCTCACATCATTCCCGATATATGCACCGAAATGAACGAAAGAAAGAGACAAGAATATCGCAGGACAAAGAGAGCGAATATAATTGCACGAAATGTGAACGTACATTTCGATTAAAGTCGATGTTAGATCGTCATATGCGTTCGCACACGTTCACACTACAAACATCGTGTAAAGTTTGTAAACAAGATTTTCCGACGTATTCGGAACTGCAAGCGCATCGAAAATCGCAACATATGGCGCTAAAATCGCATCAGTGTCAAAAATGTGGTAAAGTGTTGTCTACGGCCAAAGGACTGGAGAATCATATGTTGGTGCATAGTGGCGTTAAACCGTATAAATGTTCATTTTGTGATAAATCGTTTAAACAAATCGCGCATAAACATTCACACGAGCGATTACATACCGGTGTGAAACCATACACTTGTGTACAGTGTAATAAAAGTTTTCGACACCAGACAACGCTCATTGAACATACTCGACGACATACCGGGGAAACCCCGTATAAATGTTTGGTTTGTAATAAAGGATTTTATCGATCGGGTAAtatgaaaaaacatttaattacgCATAAGTAA
- Protein Sequence
- MKSKFQSKTYAEMIMACTSLKITETDEISLKICLVCTNQIDQSYIFYQKCHEADFILQFSYKFYKKSQNEGDIQQLANEPADKSDENFKEEEIEDESNDLLSSDFDCARSLSSDILLKEETQIDQPSKNKIKTRSNENDDIKIFQCHICLKSWISKLFLQKHMQVHSKQIHKCDICSLTFSNFISLKRHKIVHLDTKQYICNICNLNLPTTVHLTRHKIMHKNRRKFICDECGLILSKNNLLTQHKLTHRGDMRRVCEICGSDISLRNFQRHMYIHNAHKPHNCGRCGRGFTQKPELTRHKLVCTGEWRTPNDTKKLYQCTICLKTYKSNHTLSHHSRYMHRNERKKETRISQDKESEYNCTKCERTFRLKSMLDRHMRSHTFTLQTSCKVCKQDFPTYSELQAHRKSQHMALKSHQCQKCGKVLSTAKGLENHMLVHSGVKPYKCSFCDKSFKQIAHKHSHERLHTGVKPYTCVQCNKSFRHQTTLIEHTRRHTGETPYKCLVCNKGFYRSGNMKKHLITHK
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -