Bneb025434.1
Basic Information
- Insect
- Brachynemurus nebulosus
- Gene Symbol
- ZFX
- Assembly
- GCA_035578155.1
- Location
- JAPWDM010000008.1:12810111-12817006[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 15 0.0012 0.068 15.0 1.2 1 23 178 201 178 201 0.91 2 15 5.7 3.1e+02 3.5 0.3 3 20 294 311 293 313 0.88 3 15 2.4 1.3e+02 4.7 1.6 1 23 323 345 323 345 0.93 4 15 2.4e-05 0.0013 20.4 0.7 1 23 351 373 351 373 0.98 5 15 4.7e-05 0.0025 19.5 0.2 1 20 379 398 379 401 0.93 6 15 0.00028 0.015 17.1 2.6 1 23 407 429 407 429 0.98 7 15 2.6e-06 0.00014 23.4 3.0 1 23 434 456 434 456 0.98 8 15 7.7e-05 0.0042 18.8 1.4 2 23 592 614 591 614 0.94 9 15 0.15 8 8.5 2.1 2 22 673 693 672 693 0.95 10 15 2.5e-05 0.0013 20.4 6.1 3 23 715 735 713 735 0.96 11 15 0.0018 0.096 14.6 2.8 1 23 741 763 741 763 0.98 12 15 3.4e-05 0.0018 20.0 0.2 1 23 769 791 769 791 0.97 13 15 2.6e-05 0.0014 20.3 0.4 1 23 797 819 797 819 0.97 14 15 7.2e-06 0.00039 22.1 1.5 1 23 825 847 825 847 0.99 15 15 0.00059 0.032 16.1 5.2 1 23 853 876 853 876 0.98
Sequence Information
- Coding Sequence
- ATGCACGAGAAAAAGTGTCGAACTTGTTTATCAGAACGAGCTGACGAACTACTACcattattttctattaataattacataaacaGTTCGTTAACAAATGCTGAACTGATAATGGCATGTTCTTCAGTAAAaattACTCAAAACGATGAATTTCCTCAAAATATTTGTGGAGcttgttataataaattatcgCAATCATATGAATTCaaattactttgtgaaaattcagataaaattttacgtagcTTTCTTAAACACGAGGAAGTTCAAATTGATGATGTAGAATATTTTGAGGATTCACTTAATAATGTAGACGAAAGTTTTACTGTCGAAGATACCACCGACGAAGATGAAAACAGTAACATTACGAATGTGAAAATAGATTCAAAAGAAGCAAAGAAAGATAGTAATAATCTATCAACTTGCATATCTGTCAACAAAGAGAAAAACAGTGTTACCAACCTCTCTAAGCTGGAACCGGGAAGTCCCGAAAGAATTATCCTATCAAACAATATACCGCTAAGAATTCGCTACGCCTGTTCCAGATGTAAGAAACAGTTTAACACTAAAGATGAACTTCGAATACATTTTGAACAAGTACATCCTGAAATTCGTCCCGCCATACTTGAAGATGGCGACAAAGTAAATAACGCAATTAAAAAAGCGCTTGAAAATTTTCAACCGCAGCATAAAACGGTCCatagaaaaaaatctaaaaagaaaaaagagcACAGCCCTAAGAAAAAAACCGATAAAATCGATTCCAAAGAAAATGGTCAAGAAGAGACACCTGAAAAGGTGTCCGTGTACTGTATACTTTGTAACGAGAGTTGCGAAAATGTTAAGAAACATTTCAAACATATTCACCAAAAAAAGGATTGTTCAAAGTGTGGTAAACAATTAATTTCGTTTCTTCGATTCTCGAGACATATGGAGGGCAGATGTCTTGAGAAATCGAAAAGAACATTTTTGTGCTCTTACTGTGGATTGGTCACCGAATGTGATTCCTTCTTTGCTAGACATATGAAAATTCACACGGGCGAAAAACCGTACAAATGTGATATTTGTGGTAAAACGTTTCGTGTGTCAACTACTTTAGTCGGTCACAGAACGACTCATACTGGGGAAAAGAATTATGCTTGCGAAATTTGTGGTCGTAAATTCGCCAGAAAGAATTGGCTTTCGAAACATATGCCAGTTCATTCCGATGAACGTAAATACTCATGCCATATTTGTGCCAAAacgtttaaatataaaaaatccgTTAAACTTCATATGGCAGTGCATGgtatTAGTAACTTTAAATGTAAAGAATGTGGTAAAGAAttcaaatacagaaaaaatctAAAAGATCATCGACAAATTCATACTGCCAGTGCTGCCAATAGTCAGGTGGAATCTGAAAATAATCAGatTACTCAAAACGACGGATTACctcaaaatatttgtaataattgtTATGATAAACTACTACAGTCGTACGAATTTAAATTATTGTGCGAAAATTcggataaaattttacatagtgTCGTGAAACAGGAGGAAGCTGATAATGAAGATGATCATGAAGTATATGTTGaagataattataatttaagtgACGATAATGTAAcggaaaatatcaaaattgaaaaaaatgaaccGAATACTTCCGATGTTTATAAGAAATATGCGACATTCTGTTCAAAACAGATTGACTCGTTGAATAAACTTAAATCAGCAAGCACCGAAGTAAAACCTGTTCGTGATAAttccgaattaaaaattaacgtaGTATGTTCAAAGTGTACGAAGAGTTTCAATAATAAAGaagatttgaaaaaacattttgaacgCATCCATCAAAATGCGTTCCCTACATTACCGACCGCCCCCCACCAATCAACCGATAAAGTGAAGACcgaagaaacaaaaaaaagtcccGCGAAAAAAGAACCACCAATCACGAAATGTTTAATATGCCagggtaattttaaaaatatcttagcTCACTATCATCAGGAGCATAAAGTGAAAAAATGCCCAAATTGCAAACAACagtttataaaattcaatttcttCCTACGACATATGCGCTCTGAATGTGGCAAAAGGCCACCAGGAAGTCGTCCATCGTTGTCGTCGGAGAAACAGAAACATTTATGCTCGTACTGTGGACACTGTTTCACcgattattcaaatttaaaagcaCATTTACGAATACATACCGGAGAAAAACCGTATAGTTGCGAATTCTGTGATCGAAAATTTGCTCAGTGGTCAAGTATACACTATCACAGACTTACCCATACGGGTGAAAAAAGGTTTGCTTGTGAAATTTGCGGCAAAGCATTCGGTACAGCTTACCGTCTTAAAAATCATACACTGACACATTCGGATGAACAAAAGTATTCATGTGAAGTATGcagaaagaaatttaaaaatccgAGTACAGTTAAAGCACATATGGTGGTGCACACTGgtCTTAAAGATTTCAAATGTGAATTTTGTGGAAAAGCGTTTGGATTTAAAAAGAATCTTGTAGTCCATCGACGGACTCATACCGGTGAAAAACCGTTCGTTTGTGAAATATGTTCGCAAAGATTTACGCAACGTCACTGTTTACGGGGTCATATGCGGTCTCAGCATAAACAACAATCGCCAACACCCGAAGTTAAagattttaatttgattaacgactttaattaa
- Protein Sequence
- MHEKKCRTCLSERADELLPLFSINNYINSSLTNAELIMACSSVKITQNDEFPQNICGACYNKLSQSYEFKLLCENSDKILRSFLKHEEVQIDDVEYFEDSLNNVDESFTVEDTTDEDENSNITNVKIDSKEAKKDSNNLSTCISVNKEKNSVTNLSKLEPGSPERIILSNNIPLRIRYACSRCKKQFNTKDELRIHFEQVHPEIRPAILEDGDKVNNAIKKALENFQPQHKTVHRKKSKKKKEHSPKKKTDKIDSKENGQEETPEKVSVYCILCNESCENVKKHFKHIHQKKDCSKCGKQLISFLRFSRHMEGRCLEKSKRTFLCSYCGLVTECDSFFARHMKIHTGEKPYKCDICGKTFRVSTTLVGHRTTHTGEKNYACEICGRKFARKNWLSKHMPVHSDERKYSCHICAKTFKYKKSVKLHMAVHGISNFKCKECGKEFKYRKNLKDHRQIHTASAANSQVESENNQITQNDGLPQNICNNCYDKLLQSYEFKLLCENSDKILHSVVKQEEADNEDDHEVYVEDNYNLSDDNVTENIKIEKNEPNTSDVYKKYATFCSKQIDSLNKLKSASTEVKPVRDNSELKINVVCSKCTKSFNNKEDLKKHFERIHQNAFPTLPTAPHQSTDKVKTEETKKSPAKKEPPITKCLICQGNFKNILAHYHQEHKVKKCPNCKQQFIKFNFFLRHMRSECGKRPPGSRPSLSSEKQKHLCSYCGHCFTDYSNLKAHLRIHTGEKPYSCEFCDRKFAQWSSIHYHRLTHTGEKRFACEICGKAFGTAYRLKNHTLTHSDEQKYSCEVCRKKFKNPSTVKAHMVVHTGLKDFKCEFCGKAFGFKKNLVVHRRTHTGEKPFVCEICSQRFTQRHCLRGHMRSQHKQQSPTPEVKDFNLINDFN
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -