Basic Information

Insect: Brachynemurus nebulosus
Gene Symbol: VEZF1
Assembly: GCA_035578155.1
Location: JAPWDM010000003.1:67886187-67889410[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 20 3.2e-05 0.0017 20.1 1.2 2 23 207 228 206 228 0.97

2 20 9e-07 4.9e-05 24.9 0.4 1 23 236 258 236 258 0.99

3 20 1.5e-05 0.00083 21.0 0.7 1 23 264 287 264 287 0.98

4 20 0.0014 0.076 14.9 1.0 2 23 293 314 292 314 0.97

5 20 1.2e-05 0.00066 21.4 3.0 1 23 319 341 319 341 0.97

6 20 0.00049 0.027 16.3 4.9 1 23 347 370 347 370 0.96

7 20 9.4 5.1e+02 2.8 0.3 2 23 378 398 377 398 0.86

8 20 0.00091 0.05 15.5 2.6 1 23 403 426 403 426 0.96

9 20 0.00016 0.0089 17.8 0.2 1 23 435 458 435 458 0.95

10 20 1.3e-06 7e-05 24.4 1.4 1 23 466 489 466 489 0.98

11 20 5.6e-05 0.003 19.3 3.0 1 23 495 517 495 517 0.97

12 20 0.00076 0.041 15.7 0.1 1 21 523 543 523 544 0.95

13 20 0.0076 0.41 12.6 1.2 2 23 684 705 683 705 0.93

14 20 0.00074 0.04 15.8 1.1 1 23 711 734 711 734 0.98

15 20 0.012 0.63 12.0 0.5 2 23 742 762 741 762 0.97

16 20 7.2e-05 0.0039 18.9 0.6 1 23 768 791 768 791 0.98

17 20 1.5e-05 0.0008 21.1 0.7 1 23 802 824 802 824 0.95

18 20 0.00017 0.0095 17.7 1.9 1 23 830 853 830 853 0.97

19 20 0.00034 0.018 16.8 1.4 1 23 859 881 859 881 0.98

20 20 0.0016 0.086 14.7 2.9 1 23 887 909 887 909 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	20	3.2e-05	0.0017	20.1	1.2	2	23	207	228	206	228	0.97
2	20	9e-07	4.9e-05	24.9	0.4	1	23	236	258	236	258	0.99
3	20	1.5e-05	0.00083	21.0	0.7	1	23	264	287	264	287	0.98
4	20	0.0014	0.076	14.9	1.0	2	23	293	314	292	314	0.97
5	20	1.2e-05	0.00066	21.4	3.0	1	23	319	341	319	341	0.97
6	20	0.00049	0.027	16.3	4.9	1	23	347	370	347	370	0.96
7	20	9.4	5.1e+02	2.8	0.3	2	23	378	398	377	398	0.86
8	20	0.00091	0.05	15.5	2.6	1	23	403	426	403	426	0.96
9	20	0.00016	0.0089	17.8	0.2	1	23	435	458	435	458	0.95
10	20	1.3e-06	7e-05	24.4	1.4	1	23	466	489	466	489	0.98
11	20	5.6e-05	0.003	19.3	3.0	1	23	495	517	495	517	0.97
12	20	0.00076	0.041	15.7	0.1	1	21	523	543	523	544	0.95
13	20	0.0076	0.41	12.6	1.2	2	23	684	705	683	705	0.93
14	20	0.00074	0.04	15.8	1.1	1	23	711	734	711	734	0.98
15	20	0.012	0.63	12.0	0.5	2	23	742	762	741	762	0.97
16	20	7.2e-05	0.0039	18.9	0.6	1	23	768	791	768	791	0.98
17	20	1.5e-05	0.0008	21.1	0.7	1	23	802	824	802	824	0.95
18	20	0.00017	0.0095	17.7	1.9	1	23	830	853	830	853	0.97
19	20	0.00034	0.018	16.8	1.4	1	23	859	881	859	881	0.98
20	20	0.0016	0.086	14.7	2.9	1	23	887	909	887	909	0.99

Sequence Information

Coding Sequence: atGGAAGAATTAATCACTTTTAACGATTTCGGTAAAATATGCCGTATCTGTTTGGCCACAAAAGAAGATATGATCACAATAAATAGTCCAGATCTAATTCATATGTTAGAAGAGTGCACTTCCATGCAAGAGTCCATGTACGATAAATTACCGCAACAAATTTGTAAACACTGTTTGTGGCAACTGAAGACTGCGTACGAATTTAAACAACAAAGTGCCATAGCGTTAGATAtcctatgtaaaattttattgaaacagGAAAGCGAAGAGAATGCATGTACAGTTGAGTCTCACGAAAGTGATGAAGTTCCTCGGATTAAAGTTGAAGTGGAAATCGATGAATGTGCTACGCACGAAAATCGAAAAAGTTCTAGAATTGAATTAAAAAGAGAatgcaaatacaaaaataaaaaagagcGGGAATTATCCTCAGATGACGCTGATGAAGATTATAAGGAAGAAAATGAAGATGACGAATCATCGATAAACAGCGACGACGTATCACGAGACAAATCGGACAATCCCGTCTGGTCGGAATTAGAGAAATTAGAACTGCAGAAGCAACGACAAAAGTCCCTAGCGGATATTCTAatcaaaaagtataaaatttacgaTCTAACGTGCAACATCTGTAAAAAAGAATTAACCACCCGATCCACGCTGTTGCGACATATGGAAACGCACAGTAAAAACCgcacttttaaatttcaatgTCCCGCGTGCAACAAAGGATTTTCCGATCGAGGCAACTTGAACAAGCACATTAATCGACACGAGGGAAAAGCCGACTATAAGTGCGATGATTGCTCGAAATCGTTCTACGAACTGAGCGCATTAGCGAAACATGCGCGGACACGTCACGCGGCTGAACCCATCCAATGCGGCAAGTGTCCGCAAACATTTTATCATCGACTCCAACTGGAAGCGCACGAACAGACGCACGAAAAAAAGGAATTCATTTGCGATATGTGCGGTAAAATTTTCACTCAAAAATATCACCTAAACCTGCATAAAAGCACGCACTCGGAACAACGCCCGTACACCTGCACCATCTGTAACAACTCATTCAAACACAAATTCACACTGAAAACGCATATTCAGTTGCGGCATGTCGACGCCGAACGTCGCGATATGTGCAACGTATGCGGTAAACTAATCCACCCTGGTGGCATGTATCAACATCTAGAAACTCACAAAAACGAAACGTTCAAATGTCCCGACTGTGACCGAGTCTATAGCAATAAATACGTTATGCACACACATCGAAAACAAGTACATAAGAGCGGGGGAACCCCCAAACGACATATCTGTGAATACTGTAAGAAACCGTATCCGTACGCTTCGAGTTTGCGCGCGCATATAGATATGGTGCACAGTGGACCAAAAGAGCGGCTATTTCAGTGTCATCTGTGTGAAAAATCGTACACTAGACAGGGACTTTTGAATGCGCATATACGACGGGCACATATCAATGAAAAAACGCATGTGTGTCCCACGTGCAATAAAGCGTTCTATACGAAATCGGAATGGAAAAAACATAATCGATCTCATACCGGGGAACGACCTTACGCCTGTACGATTTGCGGGAAAGCGTTCGGgtttaaaaatgttcttaatACTCATATGAAAGTTTGGTATCAAGATGAACTACCCCAACAAATTTGTACTCTGTGCCACGAAAAACTCCAGAACGCCTATAATTTAAGACAAATTTCGGAAACTTCCGATAAACAGTTAAggcaattattacaaaaaaaatgtaaaaggcaaactaaaaatatttcaatccCCGAAAGCTCAGAAGCTGAAAACAGTGGCGACGAAGATTTCGTTCCAGTGAAAATCGAATTTAATGatcaaaatgataatttttctgACAAAAATTCGGATTCCCATTCTCCCTCACCGAAGGAAGTGGTCTTCGACGTGAAGAAAGAAGAAATAGACAATGAAATGAAAGCCGAAATTAGACCTTCCGATGAAAATTGCTTAACCATAAAACCGAGGAAAAAGCGAAAATACACTGCTACGAATAAAGACGAAAATCTAGAATGTGAAATTTGCCAAAAAGTGTTCCTAAACCGACATAAACTAAAAAAACACCTAGTGGCCCATTCGAATGTTCGACCATTCCAGTGTACACTTTGCCCAAAAGCGTTCAAAGAAAAATTCATACTCAACAAACACTTAAAAACGATTCACACCGACCCGGCTCGAAGAAAAGTTTGCCAAATATGTGGTCGTTCGATTGTAAAAACATCGCTTGAACGACATCTAAAAACCCACGAGAATCCCCCGTCATATCAATGCAATGAATGCACGAAAAAATTCTTAGACGCCGAGACGCTCGAAAAACATATTCGCCGTGTTCACAAAAAGGAAACGTCACTCGATCTTTATCCGTTTTTATGTAACACGTGCGGTAAAGGATTAATATCAAAAAGTGAACTCAAACGACACATGAACTCACACTTAAAAGAAGCCAATTTTAAATGTACTCGTTGCGGCAAAGCGTACACTTCACACGCGGGACTTCGAAGTCACGTGAAAGTGTTTCATTTGAATGAACGGCCGTTCGTGTGTTCGGTATGTTCGAGAGCGTTCCCCacgaaaattatattgaaacatCATATGCGGACACATACTGGGGAAAAACCGTTCAAATGCCTCATTTGTACAAAGACTTTTGCCTTAAAGTGTGTATTACAGACACATATGAAAGTTCATAGCTAG
Protein Sequence: MEELITFNDFGKICRICLATKEDMITINSPDLIHMLEECTSMQESMYDKLPQQICKHCLWQLKTAYEFKQQSAIALDILCKILLKQESEENACTVESHESDEVPRIKVEVEIDECATHENRKSSRIELKRECKYKNKKERELSSDDADEDYKEENEDDESSINSDDVSRDKSDNPVWSELEKLELQKQRQKSLADILIKKYKIYDLTCNICKKELTTRSTLLRHMETHSKNRTFKFQCPACNKGFSDRGNLNKHINRHEGKADYKCDDCSKSFYELSALAKHARTRHAAEPIQCGKCPQTFYHRLQLEAHEQTHEKKEFICDMCGKIFTQKYHLNLHKSTHSEQRPYTCTICNNSFKHKFTLKTHIQLRHVDAERRDMCNVCGKLIHPGGMYQHLETHKNETFKCPDCDRVYSNKYVMHTHRKQVHKSGGTPKRHICEYCKKPYPYASSLRAHIDMVHSGPKERLFQCHLCEKSYTRQGLLNAHIRRAHINEKTHVCPTCNKAFYTKSEWKKHNRSHTGERPYACTICGKAFGFKNVLNTHMKVWYQDELPQQICTLCHEKLQNAYNLRQISETSDKQLRQLLQKKCKRQTKNISIPESSEAENSGDEDFVPVKIEFNDQNDNFSDKNSDSHSPSPKEVVFDVKKEEIDNEMKAEIRPSDENCLTIKPRKKRKYTATNKDENLECEICQKVFLNRHKLKKHLVAHSNVRPFQCTLCPKAFKEKFILNKHLKTIHTDPARRKVCQICGRSIVKTSLERHLKTHENPPSYQCNECTKKFLDAETLEKHIRRVHKKETSLDLYPFLCNTCGKGLISKSELKRHMNSHLKEANFKCTRCGKAYTSHAGLRSHVKVFHLNERPFVCSVCSRAFPTKIILKHHMRTHTGEKPFKCLICTKTFALKCVLQTHMKVHS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: -
90% Identity: -
80% Identity: -