Basic Information

Insect: Bombyx mori
Gene Symbol: -
Assembly: GCA_027497135.1
Location: CP114962.1:163550-169447[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 10 0.0011 0.062 13.8 2.4 2 23 235 257 234 257 0.94

2 10 0.0013 0.075 13.5 6.5 1 23 263 285 263 286 0.95

3 10 1.3 74 4.1 0.7 1 23 290 312 290 312 0.96

4 10 0.013 0.7 10.5 1.1 1 12 316 327 316 329 0.91

5 10 1.5 83 4.0 0.9 3 23 437 458 436 458 0.90

6 10 2.9e-05 0.0016 18.8 2.7 1 23 462 485 462 485 0.95

7 10 0.00052 0.029 14.8 1.2 3 23 507 527 506 527 0.97

8 10 1.5e-06 8.5e-05 22.8 0.2 1 23 533 555 533 555 0.98

9 10 0.0012 0.068 13.7 3.0 1 23 561 583 561 583 0.98

10 10 1.2e-05 0.00069 19.9 0.2 1 23 589 612 589 612 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	10	0.0011	0.062	13.8	2.4	2	23	235	257	234	257	0.94
2	10	0.0013	0.075	13.5	6.5	1	23	263	285	263	286	0.95
3	10	1.3	74	4.1	0.7	1	23	290	312	290	312	0.96
4	10	0.013	0.7	10.5	1.1	1	12	316	327	316	329	0.91
5	10	1.5	83	4.0	0.9	3	23	437	458	436	458	0.90
6	10	2.9e-05	0.0016	18.8	2.7	1	23	462	485	462	485	0.95
7	10	0.00052	0.029	14.8	1.2	3	23	507	527	506	527	0.97
8	10	1.5e-06	8.5e-05	22.8	0.2	1	23	533	555	533	555	0.98
9	10	0.0012	0.068	13.7	3.0	1	23	561	583	561	583	0.98
10	10	1.2e-05	0.00069	19.9	0.2	1	23	589	612	589	612	0.96

Sequence Information

Coding Sequence: ATGTGGAACGATACTCAAAACGCGATTTTTATGCCGAAACACGAGATAAAATCCGAACTGATGTGCTGTAGGGGATGCTTAGGGACGGGCAGGCTGTACAACATGCACCAGTACGGACTGGCGGAGCCTTATTCACTGCTCACCGGAATTGAGTTGACAGATCCAAATCGTCCGCAGCAACTCTGCAGTATGTGTAGAGCCCTACTTATCAAGTACTTGTCATTCAGAAGACGATGTCATGAAGCCGAGATGCTCCTACAGAGTTTGGCAGAAGTTAATCCGGTTCTAACAGTGGACAGCATATCGACCATAGACCGATTGACGCACCGTCTCAATCCATGCAACCAAACGTCTCCAACGAACGTTGCCTACCCGGAAATCGAGGAGGAACCACCGATAGAAGCACCACAAGAAGACATGATCTACGAAGAGCCCCCTCCCAGTCCGGAACGAAAGAAGAAGCTTAAAAAGTCCAAGCGAAAGTTCTCGTTTGACGTCGAAGACTTGCAGCCTCTGAGCACGATCAAAACGGAGAAATTGAAACCGAAGAAGAGCAGGGTCAACAATCTGTATACGGACCCCGCGGACAGGGCCAAGTTCTCGGAGCGGTACGACGTGGACATCGTCGTTATGAGGAAGGAAGACGAATACCAGGAGATGACGGACAGGAGGAACAGCGAGAAGTACTTGAGGGCCCATAACAAATGCGAGCAGTGCTACAAGGGGTTCATACACGAGGATACGCTGAAGAGGCACGTCAAAGATAAACATGATGTTAATCTGGAGCACGTCTGCGAATACTGCAAGTTCAGGTTCAAAGAAAGGTCGAACTTGTCGGGGCATTACCGGAGGCACCACAAGTACAAGTACATATGCCGGGCCTGCGGGATCACCACGAGGATGCGCGAGCACGCGGTGCAGCACTCCAAGATGCACACGCAGAAGTTCGAGTGCAAGTACTGCGGGAAGGTCTTCAATTCCACCCCGCTCCCTGCGCCGGCGCCTGCGGCGGGGCGCGGGCTCAGTCCTTGCTGTTGCAGCACGAAGGGCACGACGTACCACACGCACGTACGCAGCAAGCACGGCTCCGAGCTGCCCTGGTGCAGGATATGCGGGGACGCCTTCATCAGCACCAAGACTCACATGGAGAGACTCCACAAAGAGGTGCTGAACCTGCCCGCGGCGCTGCGCTGCGCCGAGTGCGGCACGCAGTTCCTGAGCGAGCGCGCGGCGCGGGGGCACGCGGCGGGGGGTGCAGGGGGGCCGGCGGGGGGCGCGGGGGCGGCGCGGTGCGCGGGGGGCGCGTGCTGCGTGCACTGCGCCCAGCGGTTTGACGGGGAGCGCGCGCTGCGGGACCACGTGCTCGCCGTGCACAAGGTGCAGTACTCCTGCGCGCAGTGCAACAAGACGTTCAGCCATGAGAGCAAGCTGAACAACCACCTGCTGGAGAAGCACAGCGAGGGCGAGGCCGACGCGCCGCCCGGCAGGAAGCGGTACATGAAGGTAGCGCCCGCGATGTGCCACATCTGCGGGAAGATAATAGCGGACCAGTACCACATGGTGTACCACCAGCGGATCCACACCGGGGAGAAGCCGTACGCGTGCTCCGAGTGCCCCAAGCGGTTCCGCATGCCGGAGCAGCTCCAGAACCACGTGCGCATCCACACCGGCGAGCGGCCCTTCAAGTGCAAGTACTGTCCCAACACGTTCAAGACGTACCCGGCGATGAGCAGACACCACCTCGTGCACACGGGGGTCCGGCGCCACGCCTGCTCCGTGTGCGACAAGGGCTTCGCCACCAGCGCCGAGATGAAGGCGCACGTGCGGACCGTGCACATGAAGATCCCGGCGCGACCCCGCCCCCGCAGGTACCGCGCCGCCGCCCCCTAG
Protein Sequence: MWNDTQNAIFMPKHEIKSELMCCRGCLGTGRLYNMHQYGLAEPYSLLTGIELTDPNRPQQLCSMCRALLIKYLSFRRRCHEAEMLLQSLAEVNPVLTVDSISTIDRLTHRLNPCNQTSPTNVAYPEIEEEPPIEAPQEDMIYEEPPPSPERKKKLKKSKRKFSFDVEDLQPLSTIKTEKLKPKKSRVNNLYTDPADRAKFSERYDVDIVVMRKEDEYQEMTDRRNSEKYLRAHNKCEQCYKGFIHEDTLKRHVKDKHDVNLEHVCEYCKFRFKERSNLSGHYRRHHKYKYICRACGITTRMREHAVQHSKMHTQKFECKYCGKVFNSTPLPAPAPAAGRGLSPCCCSTKGTTYHTHVRSKHGSELPWCRICGDAFISTKTHMERLHKEVLNLPAALRCAECGTQFLSERAARGHAAGGAGGPAGGAGAARCAGGACCVHCAQRFDGERALRDHVLAVHKVQYSCAQCNKTFSHESKLNNHLLEKHSEGEADAPPGRKRYMKVAPAMCHICGKIIADQYHMVYHQRIHTGEKPYACSECPKRFRMPEQLQNHVRIHTGERPFKCKYCPNTFKTYPAMSRHHLVHTGVRRHACSVCDKGFATSAEMKAHVRTVHMKIPARPRPRRYRAAAP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00236152;
90% Identity: iTF_00236152;
80% Identity: -