Basic Information

Insect
Bombyx mori
Gene Symbol
-
Assembly
GCA_027497135.1
Location
CP114960.1:15188363-15202898[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 11 0.0011 0.061 13.8 2.5 1 23 246 269 246 269 0.97
2 11 5.6e-06 0.00031 21.0 2.5 2 23 277 298 277 298 0.97
3 11 2.6 1.5e+02 3.2 0.8 1 23 302 324 302 324 0.96
4 11 8.3e-05 0.0046 17.4 2.2 1 23 329 352 329 352 0.97
5 11 0.14 7.7 7.2 0.5 3 23 359 380 359 380 0.95
6 11 3.4 1.9e+02 2.8 0.3 2 20 390 408 390 410 0.90
7 11 3.1e-05 0.0017 18.7 0.9 3 23 422 443 421 443 0.94
8 11 0.0005 0.028 14.9 1.0 1 23 452 475 452 475 0.96
9 11 0.0065 0.36 11.4 0.2 2 23 484 505 483 505 0.97
10 11 2.3e-06 0.00013 22.2 0.4 1 23 511 533 511 533 0.96
11 11 0.00072 0.04 14.4 0.3 1 22 539 560 539 560 0.95

Sequence Information

Coding Sequence
ATGGAGAAATCTGAAAAGCTTTGCCGAGCGTGCCTTGGTGTAGAAAACCTAAAGAAAATTGAAAACTCGCAACTTGAAGAAACGTTCAGATTATTAAGTGGTGACCAAGTGTTCTCATCTAGGAAACCATATATCTTCTGCCATCTATGTCATGCACAGTTGTTAATATGTCATCGATTCAGAGAAAGATGCCAACACTCAAATGAGGTTCTGGAACAAACATTGAACAATGAAGTGCTTGATAGTGATGATATCTCAACACCTTCACATGTTAAAGCCACAGCAGAAAAAGTTGAATATAATGAAAGCAAAAATCCTATTTTAACTGAAGTCTACATTGAATATGAAAATAAAGAAAGAGATGATACAAACATTAAAGATGAAAACATTAAAGAACTAGTCAATGTTAATATAAAAAATGAATTAAATGACCATGATTGCAAAAATGTTTGTGAATCTAATGAGGGACTAGATGATTTGGATACAGAAATACACAAGAAAAATACCTTAACGAAAGAATTGGTGGAAAATGAAGAAAAAACATTGGTAACCGAATTAAATAATGAAATAAAAAAACGGACACGTAAAAAAAAATTTAAGCAGATAGGTAAATATTTTGAAACAAAACAGAACATGGCCAATTTTGAACATACATATGATTTGAATATAATAACTTTGAGTACCGAAGATCAATACAAAGAGATTTTGAAACGTAAAAATGGCTTTTCATATCCATTCAGATGCAGCCTATGCTACAAAAGTTATATGGACGATGATAACTTGAATAAACATTTTAAAAAGTTGCATGATCCTAGTCGAGGCGATGAGGTGTGTGATATATGTAAGACACGTTACAGAGACAAGAAAATGTTGAAAAGACACATGAAGACGCATCGCTTGAAGTTTGCCTGTAGACAGTGTAAACATGTCTCTATACTTAGCTCCCAAGCAGTAGAACATTACAACATGCACAGAGGCCAGGTGTACAAGTGTCAAAACTGTGATAAGACTTACGACAAACAAACCACATACTTAGCGCACATAAGGTACAGTCACCCGTCGAAGTGCATCTGGTGCGAGCTGTGTGGCGAGTCCTACGTCTCCGAGACCGGCCTCAAGTGTCACCAGAACTTGGTCCATAAGGAGTTGAAATACCCACCGAACGCTAAATGCGCAAATTGTGAAACACGATTTCTGAATAATGAAGCCTATCGGACGCACAGCATGTCGTGCAACAAGTCGGCGAGCATGCCGGGCGCTGCGTGCGCTCACTGCGGCCGCAGCTTCGACAGCAGGTCGTCGTTACGCGAACATCTGTTAGAAACTCACGGGAACAAAAAGAATGATAAACTTTACCCCTGTACCAAGTGCAAGAAGACGTTCGCGCGTGCGTCGCGGCGGGGGGCGCACTACCGGCGCGCGCACGCCGCCCAGCGCGCGCCCGCCGTCGTGTGCGAGCGCTGCGGGAAGGCGCTGCCGAACACGACCATACTGAGGTACCACATGCGCACGCACACGGGCGAGCGACCCTTCCAGTGTCCGGACTGCCCCAAGGGCTTCGTCAAGCAGTCCTCACTCAAGAGCCACTCGACGGTGCACACGAGCGAGCGATCGTTCGCCTGCGAGCTCTGCCCAAAGACCTTCAAGTGGCGGTCCGGTCTGCGCACCCATCAACAAACCGTACAAGAAAAAAACCAACCTCAAGTCGCAGTTCCAACGATTTTCTGA
Protein Sequence
MEKSEKLCRACLGVENLKKIENSQLEETFRLLSGDQVFSSRKPYIFCHLCHAQLLICHRFRERCQHSNEVLEQTLNNEVLDSDDISTPSHVKATAEKVEYNESKNPILTEVYIEYENKERDDTNIKDENIKELVNVNIKNELNDHDCKNVCESNEGLDDLDTEIHKKNTLTKELVENEEKTLVTELNNEIKKRTRKKKFKQIGKYFETKQNMANFEHTYDLNIITLSTEDQYKEILKRKNGFSYPFRCSLCYKSYMDDDNLNKHFKKLHDPSRGDEVCDICKTRYRDKKMLKRHMKTHRLKFACRQCKHVSILSSQAVEHYNMHRGQVYKCQNCDKTYDKQTTYLAHIRYSHPSKCIWCELCGESYVSETGLKCHQNLVHKELKYPPNAKCANCETRFLNNEAYRTHSMSCNKSASMPGAACAHCGRSFDSRSSLREHLLETHGNKKNDKLYPCTKCKKTFARASRRGAHYRRAHAAQRAPAVVCERCGKALPNTTILRYHMRTHTGERPFQCPDCPKGFVKQSSLKSHSTVHTSERSFACELCPKTFKWRSGLRTHQQTVQEKNQPQVAVPTIF

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00236181;
90% Identity
iTF_00236181;
80% Identity
-