Basic Information

Insect: Bombyx mori
Gene Symbol: Bcl11a
Assembly: GCA_027497135.1
Location: CP114952.1:8722978-8731268[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.0086 0.48 11.0 2.4 2 23 73 94 72 94 0.96

2 12 0.13 7.5 7.2 0.6 3 23 102 123 101 123 0.91

3 12 0.29 16 6.2 0.1 2 23 131 153 130 153 0.88

4 12 5.7e-06 0.00032 21.0 4.0 1 23 159 181 159 181 0.98

5 12 3.1e-05 0.0017 18.7 2.2 1 23 187 209 187 209 0.96

6 12 0.0014 0.08 13.5 1.5 1 21 215 235 215 236 0.94

7 12 0.04 2.2 8.9 0.8 3 19 256 272 255 277 0.91

8 12 4.1e-06 0.00023 21.5 0.8 1 23 582 604 582 604 0.97

9 12 9.2e-06 0.00051 20.4 0.6 1 23 611 634 611 634 0.95

10 12 0.00038 0.021 15.3 3.7 1 23 642 665 642 665 0.97

11 12 0.00018 0.01 16.3 1.7 2 23 672 695 671 695 0.93

12 12 0.0029 0.16 12.5 0.3 1 22 701 722 701 722 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.0086	0.48	11.0	2.4	2	23	73	94	72	94	0.96
2	12	0.13	7.5	7.2	0.6	3	23	102	123	101	123	0.91
3	12	0.29	16	6.2	0.1	2	23	131	153	130	153	0.88
4	12	5.7e-06	0.00032	21.0	4.0	1	23	159	181	159	181	0.98
5	12	3.1e-05	0.0017	18.7	2.2	1	23	187	209	187	209	0.96
6	12	0.0014	0.08	13.5	1.5	1	21	215	235	215	236	0.94
7	12	0.04	2.2	8.9	0.8	3	19	256	272	255	277	0.91
8	12	4.1e-06	0.00023	21.5	0.8	1	23	582	604	582	604	0.97
9	12	9.2e-06	0.00051	20.4	0.6	1	23	611	634	611	634	0.95
10	12	0.00038	0.021	15.3	3.7	1	23	642	665	642	665	0.97
11	12	0.00018	0.01	16.3	1.7	2	23	672	695	671	695	0.93
12	12	0.0029	0.16	12.5	0.3	1	22	701	722	701	722	0.96

Sequence Information

Coding Sequence: ATGGAAAACAATTTACCATTTTTCAGTTTACCATTTGTAGATTCGCAGCCTTCGGAGTTAGATTATGGTAAATCAAAAGAAGAAGGCCTACTGGCTAATTTACACACGACTCTAGTATCTCAAGGTTCGTTGCTAAGCGAAGAAGATGTTTTGGCCCAGTTCCTATCTTTGGATGAACCATTGGAAGAGCCAGATCTGAATGGTCCTGCAACGTTATGCTGTGAAATATGTAAACGAAAATTCGACAATGCCAAAAAGTATTATGGACATTTGCGAGTACATTCCAAAAGCAATACTTGGTTGTGTGAGCAATGTCCTAATGCGAAATTTACGACAAAGCAACAGTTGATGAGACACAGTCTCATTCATAAGCCACTGGAGAGGGTATGGAGATGTCCTCAATGTCCACTGGCATTCGAAGCACTGTGGAGACTACAACAACATCTTTTTGCAAAGCATCTGGATTATAAACCGCACAAGTGTGATCAATGTACAAAGACATTTGACAAAAAATCAGATCTTAAGAAGCATATTAGTGTGCATACAGGGGAAAAGAAACATGAGTGTCCCGTTTGCAAGGCCAAGTTTAATGATAAGTCCAATTTCAACAGACATACTCTTCTGCACACAAATACACAACCATTTTGCTGCCCTGGCTGCGGTAGTAGGTTCAGACAGTTGGCATCAATGAAACGTCATTATCAAAATTGTAAAAAATGCAAGGGGTTGAATGAACTCGGTGATAAAACTGTCAGAAAGAACTACTGCAGGATCTGTGGAATGTCATTCCAATACAGAAGTGCTTTGTTAGAGCATTGTGTTCGCGAACACCCAGATGGAAAGAAGTCAAAAAAGAACATAGATGGCTTAAAGTTAAAAAAGAGCCCGGGAAATTTAAAGAAAGAAAACGAGAAAGACGTTTCCAATATGGTACACCCGAAGCCGGCCAGTAGACCAGAGGATAATATCATGGACGATATACTCTCAGCAGAAGATGACTACGTCACACTCACAACGCCCGATGAAATCATCAATATCTTCAATCCGCCGACGGACGTGAACAATACAGACGACATGACCCAACTAGAAGAAATAGACGACGAACTGCTGTACAATAACATCGACTTTGATAATTTTAAAGCCGGCCACATGTTTAATTTGAACACGAACGACATGGACTACAATGTCGACACTATGCCTAATGGCGAGATATTATTCGATTTCGTCGACGGTAAAAGTATCGATAATTTGCCTGAAGAGTTATTAAAAGCTGCCGAAGAGTTACCGGATAAACCTGAAGAAATGTTCGGGGCCAATGAGAACGAATGTTCGATTATATTCGAGAGTGATGTAGATCTCGAAGCCAGTAAGACTCTAGCGGCCAATCTAAATCAACTCATAGGAGAGAACAACGTTCAGTACATATCCACTGAAGACGACGACACCTTCGTCATAAGCTTGAGCAGCGAAATCAACGCCGAATTGACTGAAATGCTGAACAACATTGGTGTGGGAATGAACAGCGAAACTGTTAACTCGAAAGCTGACGAAACTGCGGAAGCGGTCAGCAACATACCCGCTATGGAGTCCATGGTCAGCGAACCGATAGTGGTGGAAATCAAACAGAAGCCGACGACCGTCACCGGTCAGTCGCTCTCATTGACACAGAATAAAATGCCCAATTCAGAAACGAAACACGGTGAATTGAAAATAAAAGGTATTAAAGGGAGGAAACTGTTTATATTCGCCTGCAGAATTTGTAATAAAGTGTTTAACAAAAAGGACAATTATACATCGCACATGGCCATCCACGAGCCGGAGCTGTGTCGGCACGTGTGCGCGGTGTGTGGCCAAAGGTTCGGGTACCGCTCCACGCTAAACAAGCACATGCGCGCCGCACACGAGCCGCGCACGCACACCGCGCACCGCTGCCACTACTGCGACCGGACCTACACCGCCGCCTGGATGttaaaagACCACATAAAATCTAAACACCAGGGTGTGATGCCCCACGCCTGCGACGTTAAGGGGTGCGGCAAGAAATTCTATAAAAAGAGCGATTTGGTTGTTCATAAAAGGTACCACACCGGCGAGAGACCGTTCTCTTGTGGCATCTGCATGCGTTCGTTTCCCATAGTGTCGCATCTCAAACGTCACATTCGTTCTGTAGACTGTACAAAATCCTTAGAGAGAAAAGCGGAAATTCATCCTTAG
Protein Sequence: MENNLPFFSLPFVDSQPSELDYGKSKEEGLLANLHTTLVSQGSLLSEEDVLAQFLSLDEPLEEPDLNGPATLCCEICKRKFDNAKKYYGHLRVHSKSNTWLCEQCPNAKFTTKQQLMRHSLIHKPLERVWRCPQCPLAFEALWRLQQHLFAKHLDYKPHKCDQCTKTFDKKSDLKKHISVHTGEKKHECPVCKAKFNDKSNFNRHTLLHTNTQPFCCPGCGSRFRQLASMKRHYQNCKKCKGLNELGDKTVRKNYCRICGMSFQYRSALLEHCVREHPDGKKSKKNIDGLKLKKSPGNLKKENEKDVSNMVHPKPASRPEDNIMDDILSAEDDYVTLTTPDEIINIFNPPTDVNNTDDMTQLEEIDDELLYNNIDFDNFKAGHMFNLNTNDMDYNVDTMPNGEILFDFVDGKSIDNLPEELLKAAEELPDKPEEMFGANENECSIIFESDVDLEASKTLAANLNQLIGENNVQYISTEDDDTFVISLSSEINAELTEMLNNIGVGMNSETVNSKADETAEAVSNIPAMESMVSEPIVVEIKQKPTTVTGQSLSLTQNKMPNSETKHGELKIKGIKGRKLFIFACRICNKVFNKKDNYTSHMAIHEPELCRHVCAVCGQRFGYRSTLNKHMRAAHEPRTHTAHRCHYCDRTYTAAWMLKDHIKSKHQGVMPHACDVKGCGKKFYKKSDLVVHKRYHTGERPFSCGICMRSFPIVSHLKRHIRSVDCTKSLERKAEIHP

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00236082;
90% Identity: iTF_00236082;
80% Identity: -