Basic Information

Insect: Bombyx mori
Gene Symbol: ZNF212
Assembly: GCA_027497135.1
Location: CP114962.1:698076-710393[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 0.032 1.8 9.2 1.6 1 23 219 241 219 241 0.98

2 12 0.0019 0.11 13.1 4.7 1 23 248 271 248 271 0.93

3 12 0.5 28 5.5 1.5 1 23 275 297 275 297 0.90

4 12 0.00083 0.046 14.2 2.1 1 23 302 325 302 325 0.98

5 12 0.0022 0.12 12.9 0.2 1 23 329 352 329 352 0.95

6 12 0.0032 0.18 12.4 0.1 3 20 369 386 368 387 0.95

7 12 2.9e-05 0.0016 18.8 0.6 2 23 399 420 398 420 0.97

8 12 2.3e-05 0.0013 19.1 0.2 3 23 441 462 440 462 0.97

9 12 2e-06 0.00011 22.4 0.3 2 23 472 493 471 493 0.97

10 12 1.3e-05 0.00072 19.9 1.9 1 23 499 521 499 521 0.99

11 12 5.6e-06 0.00031 21.0 2.0 3 23 528 549 527 549 0.90

12 12 5.3e-05 0.003 18.0 2.0 1 23 555 578 555 578 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	0.032	1.8	9.2	1.6	1	23	219	241	219	241	0.98
2	12	0.0019	0.11	13.1	4.7	1	23	248	271	248	271	0.93
3	12	0.5	28	5.5	1.5	1	23	275	297	275	297	0.90
4	12	0.00083	0.046	14.2	2.1	1	23	302	325	302	325	0.98
5	12	0.0022	0.12	12.9	0.2	1	23	329	352	329	352	0.95
6	12	0.0032	0.18	12.4	0.1	3	20	369	386	368	387	0.95
7	12	2.9e-05	0.0016	18.8	0.6	2	23	399	420	398	420	0.97
8	12	2.3e-05	0.0013	19.1	0.2	3	23	441	462	440	462	0.97
9	12	2e-06	0.00011	22.4	0.3	2	23	472	493	471	493	0.97
10	12	1.3e-05	0.00072	19.9	1.9	1	23	499	521	499	521	0.99
11	12	5.6e-06	0.00031	21.0	2.0	3	23	528	549	527	549	0.90
12	12	5.3e-05	0.003	18.0	2.0	1	23	555	578	555	578	0.98

Sequence Information

Coding Sequence: ATGGAATTTGTCGTGTGCAGAATATGTTTGAAAATAAATGTAAAAATGCATAGAATTACAAAGACTAAATTACAAATTATTTACGAGAAACTCACCAATATAAAGATTGAAAATCATGTTCTTCCCTTGCTACTGTGCTACATGTGTCGGAGGAAGCTACAGAATTGTAACGAGCTTATGTTGAAGGCTCTGAACAGCGAAATGTTTTTAGCGGAACTCGGACGTAGTGGAGTTCAGCTCACTGAACAAGTAATTGAGACAAACAGTCACCATGAAAGCTTACTAAGTCAATCAAAAATCGAAACCGTAGAGATACAAGAAGTGTACGTTAAAAAAGAAATTACAGAACAGAATATTAATGAAGATTTATCGAATGACGATGATTTGAAAGATTCACTGAAATACGATTTCAACATAGATGATGGTAATAATGCAACTGACTCGGAAGATGATGTCCCATTAAAAAGTATATTCAAGAAAGACAAAGAAAAACAGGTGCCAAGAGAAATGAGTGAATGTCAGAAAACCAATAGAAGAAGAAGTAATAAGCGAACCGAGCAAAAGATTGACTCTGAAGAAATAAAGCTGAGCAGGGAGGAGCAGATGGAGGCGCTGCTTAAGAGATCCAAGTCCTTGAATTACATTAACTCACCTTTCAAATGTAATTTGTGCTTCAGGGGATTTGTTTTTGAACAGGCTTATGTCAATCACAAGATGAAACACGATCAAGTCAACGGGCCGCACCAGTGTCCCGTGTGCAAGATGCACTACAGGACTCAACGCCACCTGAGGGTTCATTCGGTGACGGCGCACGAGAGACTGTACCGCTGCAACAAGTGTGGTACAATATCGCACACCATGAATCAGGCGAGGGATCATGAGAAGTGGCACAACGGACACACATATGAATGTCTACTGTGCGGAATGAAGTTTAGAAAGCCTACTTCGTACCTGACGCACAAACGCAAAAGGCATCCATCCAAATATATATGCAACTTGTGCGGCGAGAGCTTTATAGGAGCCCACGGACTTCTGATGCACAAGACCAAAGCACACAAATCGAGCGAATCGAATCCCGAGGACGGTTCTCCCGGGGAGGGCTTCTGCGCCGAATGCGACATTCGTTTCACGACCCTCGAAGCCTGGAAGAGACATATGATCTGTTCTATCAACCACCGATACGATAATAGTTTAAAATGTAAGATTTGCAATATAAAGTACAGCAGCGCGGATTCGTTCACGGTTCACATGAAGGAGCACTTGAAGAGTTTGAAGAGGCACCGAGGACCGCCCGGGGACACGGGCCAGACCAAAGTGGCCTGCGACCAGTGCGGCGGGAGCTTCGCGAACAAGTCAAAGCTACAAGCTCACATAAATCGAATGCACTTAGGCATAAAGTACAACAAGGATATCGTGTGCGAAGTTTGCGGGAAAAAGTTCAGCTCGAACGCCTTCCTGCGCTACCACCAGCGGATCCACACCGGCGAGAAGCCGTACTCTTGCGAGACGTGCTCGAGAAGGTTCACCGAGAAGAACCAGCTCCGGATCCACGTGCGCACGCACACCGGCGAGAAGCCGTACTGCTGCATCGTCTGCGGACGGAGCTTCAGCCAGAAGCCGGCCCTGAACCGACATTACCGGACTCACACGGGAGCGAAGCCCTACGAATGTCGGTATTGTTCAAAGAAATTCAGTCAATCGAATTCAATGAACCTCCACGTGAAGACGATACATCTGAAGATGGGCAGAGTGGCAAGTGCGAAGAAAACGGACGTGGATCCGATCGAAGTATTGCCAGAGAAGAAAAATATTTGTGTTTTTGAATAA
Protein Sequence: MEFVVCRICLKINVKMHRITKTKLQIIYEKLTNIKIENHVLPLLLCYMCRRKLQNCNELMLKALNSEMFLAELGRSGVQLTEQVIETNSHHESLLSQSKIETVEIQEVYVKKEITEQNINEDLSNDDDLKDSLKYDFNIDDGNNATDSEDDVPLKSIFKKDKEKQVPREMSECQKTNRRRSNKRTEQKIDSEEIKLSREEQMEALLKRSKSLNYINSPFKCNLCFRGFVFEQAYVNHKMKHDQVNGPHQCPVCKMHYRTQRHLRVHSVTAHERLYRCNKCGTISHTMNQARDHEKWHNGHTYECLLCGMKFRKPTSYLTHKRKRHPSKYICNLCGESFIGAHGLLMHKTKAHKSSESNPEDGSPGEGFCAECDIRFTTLEAWKRHMICSINHRYDNSLKCKICNIKYSSADSFTVHMKEHLKSLKRHRGPPGDTGQTKVACDQCGGSFANKSKLQAHINRMHLGIKYNKDIVCEVCGKKFSSNAFLRYHQRIHTGEKPYSCETCSRRFTEKNQLRIHVRTHTGEKPYCCIVCGRSFSQKPALNRHYRTHTGAKPYECRYCSKKFSQSNSMNLHVKTIHLKMGRVASAKKTDVDPIEVLPEKKNICVFE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00236067;
90% Identity: iTF_00236067;
80% Identity: -