Basic Information

Insect: Bombyx mori
Gene Symbol: -
Assembly: GCA_027497135.1
Location: CP114964.1:8813303-8821128[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.00098 0.055 14.0 0.5 1 23 459 481 459 481 0.98

2 8 4.2e-07 2.4e-05 24.6 2.1 1 23 487 509 487 509 0.98

3 8 7e-06 0.00039 20.7 0.6 2 23 518 539 518 539 0.98

4 8 7.2e-06 0.0004 20.7 0.8 1 23 545 567 545 567 0.99

5 8 2.2e-07 1.2e-05 25.5 2.7 1 23 573 595 573 595 0.98

6 8 5e-07 2.8e-05 24.4 1.3 1 23 601 623 601 623 0.97

7 8 8.3e-05 0.0046 17.4 7.3 1 23 629 651 629 651 0.97

8 8 0.00012 0.0066 16.9 1.3 1 21 657 677 657 678 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.00098	0.055	14.0	0.5	1	23	459	481	459	481	0.98
2	8	4.2e-07	2.4e-05	24.6	2.1	1	23	487	509	487	509	0.98
3	8	7e-06	0.00039	20.7	0.6	2	23	518	539	518	539	0.98
4	8	7.2e-06	0.0004	20.7	0.8	1	23	545	567	545	567	0.99
5	8	2.2e-07	1.2e-05	25.5	2.7	1	23	573	595	573	595	0.98
6	8	5e-07	2.8e-05	24.4	1.3	1	23	601	623	601	623	0.97
7	8	8.3e-05	0.0046	17.4	7.3	1	23	629	651	629	651	0.97
8	8	0.00012	0.0066	16.9	1.3	1	21	657	677	657	678	0.95

Sequence Information

Coding Sequence: ATGTGTGAATGGCTGTCGTACGCCGATTGGTGCGATGTGAAATTGCTCTGTGGCGATCGTACATTCGAGGCTCATCGTGTTGTTCTTGCCAGCGCCAGTACCTTCCTTAGGGAAATTCTCTTATCCTGCCACACGAATGAGACACCGACGCACATGATGCTACCGGATTTCGACAAGGAAGCCATGTCGGCGGTTCTACATTATATTTATAATGGGGAGGTCGTTTTACAAAAACAGAAAATGGACATGTTCTTGGATATAGTGAAAGCTATGCGAATATATATTGATTACGAACTTTTGAATCCAGAGTTAGGCTGTGTACAAAACTCTAATTCTAATTCATTTTTCAAGACAAATGCATGTCAACAAAGCTGTATATTCAGTCCGAAATCTGCAGAATGTTTTAGCGGATCTTTCGTTACTATTAAGAAAAAATCGAATATTAAAGGTATACAATATTTTCTGCAAAACTTTGATTCTCACGGAAGGCAAATTACATTTCAAGACAATAGGGGTGTACAGTGTGACAATGCTTCAAAAGATTTCAAATCACCATTTGTAGACCGACAAAGGAACTCTTTCCTACGTGATTTATTTATCGAGACATATCCTCGAAACGGTAATGTTAACGGTCAGACGAGAAGCGTGCTAGCAATATCAAATGAATGCTATCGTTCTCCGGGATCTGTGCTCTTGACGAATGCAAATGCCGAACATCTCGGCGCCGGCGACATAGATGTACAAAAATATAAAAGCACCGTCGAGATCCCCTTTCATTCGCCGACATGTCGCCCTGAACACTTGAGACAGTTTACGCAAAACCAGAATTTAATGCAAAATTATTTTCGGACCAAAGACACAAAAGAGATAATTAATCTAAGATCGTGTTATAAATATTCGAATACTGTAACGAATACAGAAACATTACCCAAAAATATGGTACCCATGTTACAGACTAACCTACAGACAACCTATTTAAATGATCACGCTCCAAACACAAATATTCAAAATATGTCGAGCTATACCCAATCAATGGCAGATATAAACGAATGTGGTATGTCTCTACAAAAGCGAACTATATTAAGAGAAAGTTCATTGCTTATTAGTCTGGCTACTGATTTTGAAAACGAATACTGCGAATCTAAAACGAATGCTAGAACTATATCGAAAGCAGCAATATCAAATCATGTTCTAGAGAACCCTTGGCGACCACGGCTACCCGTAGATGCGAAGCCTTTTCGCAGGAAATTCAAAGAATCAAGTGAAAAATTACCCTTACTGAACAAGGTGTCTGAAGCTGTTAGCGATAATAACAATAACTGTGCAACTACCCCTGCTGCACTAAGCAACCAACTTCCAGTCTTAAAAGACGAGTTCAAATGCAACATTTGTAGCCAGGTGTTTCTGTCTGACGATGCGTTGACCACACATATGAGTCGACATTCAAAAACTGCACGTTATTCCTGTAACGAATGCGGCAAAACATTCTCACAGCTGCGCAACTTCAAGTACCATATGTCGATTCACAGAGGCACTAGAGAGTTTGCAGCGACATGCACTGTTTGTGGAAAGTATTTCAACGACAGAGGATACCTAAGCAGTCATATGAAAATACATAGAAATCGTAAGGAATACAAATGTTCGCAATGTCCGAAATCTTTCAATCAGCGTGTCGCTTATAACATGCACGTAAGAATACATACAGGTGTGAAGCCTCATGTGTGCGATCAGTGCGGCAAAGCGTTTTCCCGTAAGATGCTCCTGAAGCAACATCAGCGCACACATTCGGGCGAACGACCTTACGCCTGTCCGCACTGCGACAAGCGGTTCGCTGACAGATCCAACATGACCCtccacctaagactccatactgGTGTGAAGCCATTTTCGTGTACGCTATGTCCAAAATCGTTTACGAAGAAACATCATCTTAAATCTCATTTAAACTTTCACACTGGTTCTAAGCCCTATTCTTGCCCGCGTTGTAAGCTCGCATTCACACAATCTTCGAACATGCGAACCCATTACAAGAAATGTACGGTCGCTGATCCTAATGACAATTCTGAGTTGCCACCTCAAAATTAG
Protein Sequence: MCEWLSYADWCDVKLLCGDRTFEAHRVVLASASTFLREILLSCHTNETPTHMMLPDFDKEAMSAVLHYIYNGEVVLQKQKMDMFLDIVKAMRIYIDYELLNPELGCVQNSNSNSFFKTNACQQSCIFSPKSAECFSGSFVTIKKKSNIKGIQYFLQNFDSHGRQITFQDNRGVQCDNASKDFKSPFVDRQRNSFLRDLFIETYPRNGNVNGQTRSVLAISNECYRSPGSVLLTNANAEHLGAGDIDVQKYKSTVEIPFHSPTCRPEHLRQFTQNQNLMQNYFRTKDTKEIINLRSCYKYSNTVTNTETLPKNMVPMLQTNLQTTYLNDHAPNTNIQNMSSYTQSMADINECGMSLQKRTILRESSLLISLATDFENEYCESKTNARTISKAAISNHVLENPWRPRLPVDAKPFRRKFKESSEKLPLLNKVSEAVSDNNNNCATTPAALSNQLPVLKDEFKCNICSQVFLSDDALTTHMSRHSKTARYSCNECGKTFSQLRNFKYHMSIHRGTREFAATCTVCGKYFNDRGYLSSHMKIHRNRKEYKCSQCPKSFNQRVAYNMHVRIHTGVKPHVCDQCGKAFSRKMLLKQHQRTHSGERPYACPHCDKRFADRSNMTLHLRLHTGVKPFSCTLCPKSFTKKHHLKSHLNFHTGSKPYSCPRCKLAFTQSSNMRTHYKKCTVADPNDNSELPPQN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00236065;
90% Identity: iTF_00236065;
80% Identity: iTF_00236776;