Basic Information

Insect: Bombyx mori
Gene Symbol: TEAD1
Assembly: GCA_027497135.1
Location: CP114942.1:13215499-13241725[-]

Transcription Factor Domain

TF Family: TEA
Domain: TEA domain
PFAM: PF01285
TF Group: Helix-turn-helix
Description: The TEA domain is a DNA-binding region of about 66 to 68 amino acids that has been named after the two proteins that originally defined the domain: TEF-1 and AbaA. The TEA domain is located toward the N terminus of eukaryotic transcription factors of the TEA/ATTS family. It shows a three-helix bundle with a homeodomain fold [3, 1]. Two α-helices are nearly anti-parallel and pack on either side of the third one, which is the DNA-recognition helix of the TEA domain. Phosphorylation of one or both of the two conserved serines found on the DNA-binding surface could interfere with DNA-binding activity, by introducing electrostatic repulsion and/or steric hindrance, and help regulate the transcription factor activity of the proteins [2, 1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 1 1.1e-31 2.1e-27 95.2 0.1 2 66 60 126 59 128 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	1	1.1e-31	2.1e-27	95.2	0.1	2	66	60	126	59	128	0.96

Sequence Information

Coding Sequence: ATGTTGAGTCATTTAAAAAGGCTACCGAGCGGCGCGCTCGCAGCCGGCACCATTGCGTCTCCGTGGAGCACGCCGGCCGGCGCGCCCGACACCAATGGATCGGGCGGCGCTGACGCCAAGCATCTCGATGTCGGAGACGCTAGTGACGATGAGAAGGACATGTCGGCGGCGGACGCGGAGGGCGTCTGGAGTCCCGACATCGAACAGAGCTTCCAAGAGGCGCTGGCGATATACCCGCCCTGTGGACGACGCAAAATTATTCTCTCCGACGAGGGCAAGATGTACGGAAGGAACGAGTTAATAGCGAGGTATATTAAACTAAGGACAGGCAAAACGCGTACGAGAAAACAAGTCTCGTCACACATACAGGTGCTAGCTAGGCGAAAACTACGAGAAATTCAAGCCAAACTTAAAGTGGACGGCGGAGTGATGAAGGAAAAGGCCATGCAGTCAATGAGCACGCTATCTAGCGCTCAGATCGTTGCGGGCCTACCGCATCCAGCGTACCACCATACGCAATTTTGGCAGCCAGGCCTACAAGCCGGCACATCACAGGATGTGAAGCCTTTCCCCGGAGCGGGCTACAAAGGCGTCCCCGGTGTCGGAGGCGTCGGAGTGCCGAGCGGCACCGACGTGGCGCCGCCGCCGCCCTGGGAGGGACGCGCCATCGCCACACACAAACTGAGACTCGTAGAGTTCTCAGCCTTCGTCGAGCATCCCCGGGATCCTGATACGTACCCACCGAGCACGGCGCCGGCGCAACATCTCTTCGTTCACATAGGCGGTACGGTCACATACGCGGATCCTTTATTAGAGTCAGTAGACGTTCAGCAGATAAACGACAAATTCCCCGAGAAGAAGGGCGGTCTGAAGGAACTGTACGAGAAAGGTCCGAGGAACGCCTTCTTCCTGGTCAAGTTCTGGGCGGATCTCAACACGAACAACCTCGACGACCCCGGCGCCTTCTACGGCGTCACTAGTGTATACGAAAGTAATGAGAACATGACGATAACGTGTAGCACGAAAGTGTGTTCGTTCGGGAAGCAGGTGGTCGAAAAGGTGGAAACTGAATACGCCCGGTTCGAGGGCGGTCGCTTCGTGTACCGCATCCACAGGTCGCCGATGTGCGAGTACATGGTCAACTTCATACACAAACTGAAACATCTGCCCGAGAAGTACATGATGAACAGCGTACTAGAAAACTTCACTATACTACAGGTAGTTTCAAACCGAGACACGCAAGAGACATTACTGTGCGCCGCGTTCGTGTTTGAAGTGTCGAACAGTGAGCACGGGGCGCAGCATCACATCTACAGGCTCGTCAAAGATTGA
Protein Sequence: MLSHLKRLPSGALAAGTIASPWSTPAGAPDTNGSGGADAKHLDVGDASDDEKDMSAADAEGVWSPDIEQSFQEALAIYPPCGRRKIILSDEGKMYGRNELIARYIKLRTGKTRTRKQVSSHIQVLARRKLREIQAKLKVDGGVMKEKAMQSMSTLSSAQIVAGLPHPAYHHTQFWQPGLQAGTSQDVKPFPGAGYKGVPGVGGVGVPSGTDVAPPPPWEGRAIATHKLRLVEFSAFVEHPRDPDTYPPSTAPAQHLFVHIGGTVTYADPLLESVDVQQINDKFPEKKGGLKELYEKGPRNAFFLVKFWADLNTNNLDDPGAFYGVTSVYESNENMTITCSTKVCSFGKQVVEKVETEYARFEGGRFVYRIHRSPMCEYMVNFIHKLKHLPEKYMMNSVLENFTILQVVSNRDTQETLLCAAFVFEVSNSEHGAQHHIYRLVKD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00674273; iTF_01029249; iTF_01217474; iTF_01230566; iTF_00010055; iTF_01464140; iTF_00009008; iTF_00428103; iTF_00819147; iTF_00787633; iTF_00341300; iTF_01429918; iTF_01453249; iTF_00820067; iTF_00146404; iTF_00647972; iTF_01561097; iTF_00837517; iTF_01452302; iTF_00063571; iTF_00834616; iTF_00859449; iTF_00836541; iTF_00858525; iTF_00072798; iTF_01206528; iTF_01153960; iTF_01142369; iTF_01143808; iTF_01180289; iTF_00780229; iTF_00774470; iTF_00781000; iTF_01173257; iTF_01179469; iTF_01181869; iTF_01494288; iTF_00777361; iTF_01140179; iTF_01073594; iTF_00457211; iTF_00621211; iTF_00621979; iTF_01115679; iTF_00247168; iTF_01331560; iTF_01312204; iTF_00887381; iTF_00843515; iTF_01507196; iTF_00441473; iTF_01191876; iTF_01191167; iTF_01437029; iTF_01202444; iTF_00358541; iTF_01538728; iTF_00250441; iTF_01341257; iTF_01117194; iTF_01208171; iTF_00044482; iTF_00826949; iTF_01172359; iTF_00143049; iTF_00791177; iTF_00390351; iTF_01443825; iTF_00825717; iTF_00913589; iTF_00649078; iTF_00835575; iTF_00033786; iTF_00926587; iTF_00206974; iTF_00634464; iTF_00149377; iTF_00355137; iTF_00632737; iTF_00150530; iTF_00323491; iTF_00710182; iTF_00874442; iTF_00114926; iTF_01203217; iTF_01204017; iTF_00771062; iTF_00875287; iTF_00706947; iTF_00811011; iTF_00925699; iTF_00786771; iTF_01463235; iTF_00649989; iTF_01204869; iTF_00361606; iTF_01076486; iTF_01264597; iTF_01436071; iTF_00871272; iTF_01090754; iTF_01072475; iTF_01219752; iTF_00968009; iTF_00412490; iTF_00680523; iTF_00120492; iTF_00274410; iTF_00276396; iTF_00685420; iTF_01335916; iTF_00661262; iTF_00658383; iTF_00878831; iTF_01205679; iTF_00288849; iTF_01140894; iTF_01248113; iTF_00403790; iTF_00934743; iTF_00164346; iTF_00942802; iTF_01020274; iTF_01170581; iTF_00663061; iTF_01031126; iTF_01503863; iTF_00896790; iTF_00382590; iTF_00410265; iTF_01401274; iTF_00289595; iTF_00935707; iTF_00656124; iTF_00909692; iTF_00994332; iTF_01490108; iTF_00662205; iTF_00772861; iTF_00635390; iTF_01245918; iTF_00148447; iTF_00375199; iTF_00771908; iTF_01063743; iTF_00850724; iTF_00204332; iTF_01316333; iTF_01415822; iTF_01083311; iTF_00007068; iTF_00761660; iTF_01416764; iTF_01439918; iTF_00275247; iTF_00450095; iTF_00354064; iTF_01178544; iTF_01367888; iTF_01441073; iTF_00411442; iTF_00818322; iTF_01016654; iTF_01033714; iTF_00842653; iTF_01280274; iTF_00666515; iTF_01363091; iTF_01361606; iTF_00198100; iTF_01502957; iTF_00279092; iTF_00824724; iTF_01028276; iTF_00036705; iTF_00785185; iTF_00018146; iTF_00038755; iTF_00301156; iTF_00726340; iTF_00001157; iTF_00037797; iTF_00711845; iTF_01094021; iTF_00783462; iTF_01533030; iTF_00017319; iTF_00172935; iTF_00300199; iTF_00758151; iTF_00831208; iTF_00951816; iTF_01527208; iTF_00282377; iTF_00302089; iTF_00364009; iTF_00445161; iTF_00851785; iTF_00122379; iTF_00889195; iTF_01152140; iTF_00446125; iTF_00928685; iTF_00823023; iTF_00273584; iTF_00745680; iTF_01362416; iTF_00147441; iTF_01061873; iTF_01285521; iTF_01526001; iTF_00039794; iTF_00121426; iTF_00177106; iTF_01332690; iTF_01338739; iTF_01260084; iTF_00042613; iTF_00374101; iTF_01026165; iTF_01118293; iTF_01166677; iTF_01246965; iTF_00425366; iTF_00784374; iTF_00907030; iTF_01094902; iTF_01425046; iTF_00447127; iTF_00906135; iTF_00924663; iTF_01084247; iTF_01093079; iTF_01342199; iTF_00171736; iTF_00907864; iTF_00888249; iTF_01533913; iTF_00043482; iTF_00071418; iTF_00124250; iTF_01192699; iTF_00000316; iTF_00041756; iTF_01340092; iTF_01534812; iTF_00049886; iTF_00123358; iTF_00622814; iTF_01028382; iTF_01062782; iTF_01531998; iTF_00040799; iTF_00810047; iTF_00449088; iTF_00809120; iTF_01030208; iTF_00156225; iTF_00155279; iTF_00325364; iTF_00709218; iTF_01085218; iTF_00823878; iTF_00185291; iTF_00186158; iTF_01221554; iTF_00657175; iTF_01135735; iTF_00342181; iTF_00022777; iTF_00027733; iTF_01388449; iTF_01542947; iTF_01546628; iTF_00026832; iTF_01387579; iTF_01544862; iTF_01386687; iTF_00377089; iTF_00702882; iTF_00700102; iTF_00698296; iTF_01429027; iTF_00703946; iTF_01161354; iTF_00705995; iTF_00697325; iTF_00699151; iTF_01528272; iTF_01509587; iTF_01529171; iTF_00686325; iTF_01182869; iTF_00701047; iTF_00007993; iTF_00119578; iTF_01171451; iTF_00267165; iTF_00638624; iTF_00856608; iTF_00432181; iTF_00723938; iTF_00790244; iTF_00433129; iTF_00947870; iTF_00467391; iTF_00448117; iTF_01359731; iTF_01125444; iTF_00827937; iTF_00075522; iTF_01545730; iTF_00462371; iTF_01081571; iTF_00660292; iTF_01279236; iTF_01281319; iTF_00144552; iTF_01508043; iTF_01547532; iTF_00409262; iTF_00796495; iTF_00960911; iTF_01302319; iTF_01134771; iTF_00021305; iTF_01021209; iTF_00178139; iTF_00654267; iTF_01282267; iTF_00235836; iTF_00408444; iTF_01124572; iTF_00114080; iTF_00659424; iTF_01079872; iTF_01082421; iTF_00418966; iTF_00959382; iTF_00960143; iTF_00161527; iTF_00162794; iTF_01222457; iTF_00237559; iTF_00035640; iTF_00318841; iTF_00806713; iTF_00715770; iTF_00318075; iTF_01564635; iTF_00032892; iTF_00212444; iTF_00248060; iTF_01193569; iTF_01561986; iTF_01041735; iTF_00159818; iTF_00213425; iTF_00695579; iTF_00954442; iTF_01151187; iTF_00953492; iTF_00013003; iTF_00651727; iTF_00640304; iTF_01220634; iTF_00288028; iTF_00794588; iTF_00111645; iTF_01149567; iTF_01138923; iTF_01334880;
90% Identity: iTF_00355137; iTF_00674273; iTF_00150530; iTF_01561986; iTF_01193569; iTF_00827937; iTF_00954442; iTF_01151187; iTF_00953492; iTF_00021305; iTF_00114080; iTF_00925699; iTF_00786771; iTF_01463235; iTF_00647972; iTF_01125444; iTF_01453249; iTF_00075522; iTF_01545730; iTF_01081571; iTF_01279236; iTF_00364906; iTF_01502957; iTF_00960911; iTF_01222457; iTF_01124572; iTF_01090754; iTF_01542947; iTF_01546628; iTF_01544862; iTF_01436071; iTF_01331560; iTF_00406733; iTF_00448117; iTF_01503863; iTF_00318841; iTF_00662205; iTF_01075423; iTF_00428103; iTF_00819147; iTF_00787633; iTF_00341300; iTF_01429918; iTF_00820067; iTF_00063571; iTF_00859449; iTF_00858525; iTF_01281319; iTF_01153960; iTF_01173257; iTF_01341257; iTF_01561097; iTF_00412490; iTF_00204332; iTF_00673484; iTF_01464140; iTF_00010055; iTF_01547532; iTF_00837517; iTF_00409262; iTF_01439918; iTF_01085218; iTF_01361606; iTF_01117194; iTF_01363091; iTF_00237559; iTF_01029249; iTF_01230566; iTF_00185291; iTF_00685420; iTF_00186158; iTF_01367888; iTF_01441073; iTF_01221554; iTF_01338739; iTF_00907030; iTF_00111645; iTF_01452302; iTF_01041735; iTF_01016654; iTF_00275247; iTF_00658383; iTF_00796495; iTF_00009008; iTF_00026832; iTF_00027733; iTF_01494288; iTF_00288849; iTF_00818322; iTF_00942802; iTF_01359731; iTF_00878831; iTF_00695579; iTF_00710182; iTF_00114926; iTF_01203217; iTF_01204017; iTF_00771062; iTF_01280274; iTF_00666515; iTF_00649989; iTF_00250441; iTF_00935707; iTF_00635390; iTF_00044482; iTF_00826949; iTF_01172359; iTF_00143049; iTF_01208171; iTF_00390351; iTF_01020274; iTF_00825717; iTF_00913589; iTF_00649078; iTF_00033786; iTF_00926587; iTF_00032892; iTF_00206974; iTF_00634464; iTF_01134771; iTF_00462371; iTF_00279092; iTF_00824724; iTF_01028276; iTF_00036705; iTF_00785185; iTF_00038755; iTF_00301156; iTF_00726340; iTF_00037797; iTF_00711845; iTF_01094021; iTF_00783462; iTF_01533030; iTF_00172935; iTF_00300199; iTF_00758151; iTF_00831208; iTF_00951816; iTF_01527208; iTF_00282377; iTF_00302089; iTF_00364009; iTF_00445161; iTF_00851785; iTF_00122379; iTF_00889195; iTF_01152140; iTF_00446125; iTF_00928685; iTF_00823023; iTF_00273584; iTF_00745680; iTF_01362416; iTF_00147441; iTF_01061873; iTF_01285521; iTF_01526001; iTF_00039794; iTF_00121426; iTF_00177106; iTF_01332690; iTF_01260084; iTF_00042613; iTF_00374101; iTF_01026165; iTF_01118293; iTF_01166677; iTF_01246965; iTF_00425366; iTF_00784374; iTF_01094902; iTF_01425046; iTF_00447127; iTF_00906135; iTF_00924663; iTF_01084247; iTF_01093079; iTF_01342199; iTF_00171736; iTF_00907864; iTF_00888249; iTF_01533913; iTF_00043482; iTF_00071418; iTF_00124250; iTF_01192699; iTF_00000316; iTF_00041756; iTF_01340092; iTF_01534812; iTF_00049886; iTF_00123358; iTF_00622814; iTF_01028382; iTF_01062782; iTF_01531998; iTF_00040799; iTF_00810047; iTF_00449088; iTF_00809120; iTF_01030208; iTF_00156225; iTF_00155279; iTF_00325364; iTF_01415822; iTF_01135735; iTF_00342181; iTF_00022777; iTF_01416764; iTF_00382590; iTF_01245918; iTF_00149377; iTF_00680523; iTF_00411442; iTF_00410265; iTF_00289595; iTF_01072475; iTF_01564635; iTF_00772861; iTF_00148447; iTF_00432181; iTF_00323491; iTF_01204869; iTF_01205679; iTF_00213425; iTF_00248060; iTF_00247168; iTF_01206528; iTF_00723938; iTF_00790244; iTF_01202444; iTF_01083311; iTF_00947870; iTF_00467391; iTF_00887381; iTF_00896790; iTF_01031126; iTF_00834616; iTF_00007993; iTF_00146404; iTF_00013003; iTF_00651727; iTF_01302319; iTF_00640304; iTF_00720274; iTF_00077461; iTF_01220634; iTF_00011968; iTF_00806713; iTF_00715770; iTF_01073594; iTF_01401274; iTF_00457211; iTF_00780229; iTF_00774470; iTF_00781000; iTF_01181869; iTF_00621211; iTF_00621979; iTF_01282267; iTF_01387579; iTF_01388449; iTF_01386687; iTF_00007068; iTF_00212444; iTF_00035640; iTF_00235836; iTF_00408444; iTF_00794588; iTF_00281313; iTF_00637634; iTF_00709218; iTF_01538728; iTF_01197705; iTF_00276396; iTF_01360597; iTF_00157184; iTF_01334880; iTF_00636385; iTF_00018146; iTF_00001157; iTF_00823878; iTF_00017319; iTF_00968009; iTF_01033714; iTF_00842653; iTF_00327061; iTF_01264597; iTF_00959382; iTF_00960143; iTF_00994332; iTF_00836541; iTF_00072798; iTF_00677598; iTF_01115679;
80% Identity: iTF_00235836;