Basic Information

Gene Symbol
-
Assembly
GCA_932526615.1
Location
CAKOBF010000330.1:100917-104306[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 12 2.6 1.5e+02 3.3 1.7 1 23 237 260 237 260 0.92
2 12 2.4 1.4e+02 3.4 0.7 1 22 266 287 266 289 0.82
3 12 0.16 9.2 7.2 1.5 1 23 296 319 296 319 0.97
4 12 0.0029 0.17 12.6 3.9 1 23 324 346 324 346 0.98
5 12 1.1e-05 0.00064 20.2 4.5 1 23 352 374 352 374 0.98
6 12 3.2e-05 0.0019 18.8 3.3 1 23 380 402 380 402 0.98
7 12 0.00014 0.0083 16.7 0.4 1 23 435 457 435 457 0.95
8 12 0.0054 0.32 11.7 0.4 1 23 484 506 484 506 0.98
9 12 0.00061 0.036 14.7 1.6 1 23 512 535 512 535 0.98
10 12 0.0028 0.17 12.6 2.8 1 23 541 563 541 563 0.98
11 12 0.0092 0.54 11.0 2.3 2 23 569 591 569 591 0.97
12 12 0.018 1 10.1 0.3 2 23 598 620 598 620 0.94

Sequence Information

Coding Sequence
ATGAAGTTTAAATTGGATGATACTTGTCGTACCTGTGGTGCGTTTGTCGCTGATGGAGTCTTGGTACCAATATTTGACCAAGTTGAAATCAGTACAGGAGATTCACTTTTTCAAATATCTGAAGTGCTCGAATTGATGAATATCAAGATTTCAGAAAATGACAATTTACCTCAACAGATCTGCATTAATTGCATAAACGAACTGAAAAATATTCATTTATTTCGTGATAAATGTAAACATGTTCAGGATGTACTGAGAGAATATTTCATAGAAAGTGTTATCAAAACTGAAATCCACATCGACGATACAGTTTCAAAAGAACGTCAAGACTTGGTAAAAGAAGAAAAGCCTTCAAATGATGTCCTTAACAAAAACAAAGTCGTTACTGATGATGATGAAAGTGATGAAGAAATAGACCCCAACGCTGAATCATATTTCGCGAAAGAATCAGAACTCTTACTTAACTCAAGATCCAGAGAAGAATCTAATTCTATTGATAAAGAAAATTCAAATGTAATTATTGATACATTTGAAAGTGATGAAGATTTGAAGATATTCGTGGATAAATCATCTGTTAATGAAAATCAATATACAATTTTCAATGCTGAGGAAAAACCAAAGTTAGCCAAATGCGAAAATTGTTTATTTTTTGCATATAAGCGACAAGATTTATATCATAAGACGGGTTGTACTGCAATGCAAGATATATTTTCATGTTACTATTGTTGCAAATCATATAAAGAAGAACAAGAAGTTGTAAATCATATCATTGAAACACATCCAAAAGATCGTCCATATTTGTGTCCAGTTTGTAGTGAACCATTTGATATGTATCAAAATTGTATAAAACATGTTACAGAAAACCATAATCATATTAAATTCCCATTTATTTGTGATATTTGTGTGGGTTCTTTTAAACATTTAAGAATATTACGACAACATAAACGTAAGGCACATGATACTGGAAATTATGAATGTCGTATATGTAATAAAGAATTCAAAAATATCCATAAATTTGATTATCATATTAAATcacataacaaagataaacgatttaaatgtaaatattgtccaaaatcttttatgcaaccacatcatcttaaagatcatgaagcaacacatactggtaaaagacgatattattgtaaagaatgtgataaaacattcaaaaatacatcatcatattATATTCATAAAAGAGGTCATAATAAAGAATTGCATTATTGTGAAATTTGTAAGAAAACATTAGTAGCACACATGGAAAAACATAAGAACAATGAAGATTTGAAAGATGAAATTCGTTATCTGTGTTCAGTTTGCGGAAAAAATTATGCAACATTAATTAGTTTACAGAAACACCTTTATAGCCATAATCCTTCTTTAGTTCCTGATAAAACTATAAGAAAATATAATAGAACAAAAAAAAGGACTACTGAAATATTTAAAAAATATGATTGTTCTTTTTGCGATGAAAAACTTTCTTCCTTATTAGGATTACAAAATCATCTTAAAATGCATGATGAAAATCGAAAATATAAATGTGAATTTTGTGCTGTAGGTTATAAACGTAAAGAACATTTATCAGCACATATAAATTCGAAACATACAAAAATAAAAAAATATTATTGTTCATTCTGTAATAAAGTGTTCGTATCAAGTACAACCAAAAATTCTCATGAGAAATCACATTTACCGGACAAAAACCGATGTTTATATTGTTCAAAAACATTTAAAACTTATGGAAGAGCAAAGCAGCATGAACGTACATATCACACTAAAGAAAACGTTCGAGTGTGTGTCATTTGTAATGCAGTATTCACCACTTATATTCAATATAGATATCATCAAGTAAAAAAGCATTCAGAAGAAGAAATAAGGACAGCAAAAGAAAAGATTCTAACTGAGAATTTAAAATCATGTACAAATGAAAGTGACAATATTGAAGAAGAAATTATGAATGATCAAAGAGTGGACGACAGTTAA
Protein Sequence
MKFKLDDTCRTCGAFVADGVLVPIFDQVEISTGDSLFQISEVLELMNIKISENDNLPQQICINCINELKNIHLFRDKCKHVQDVLREYFIESVIKTEIHIDDTVSKERQDLVKEEKPSNDVLNKNKVVTDDDESDEEIDPNAESYFAKESELLLNSRSREESNSIDKENSNVIIDTFESDEDLKIFVDKSSVNENQYTIFNAEEKPKLAKCENCLFFAYKRQDLYHKTGCTAMQDIFSCYYCCKSYKEEQEVVNHIIETHPKDRPYLCPVCSEPFDMYQNCIKHVTENHNHIKFPFICDICVGSFKHLRILRQHKRKAHDTGNYECRICNKEFKNIHKFDYHIKSHNKDKRFKCKYCPKSFMQPHHLKDHEATHTGKRRYYCKECDKTFKNTSSYYIHKRGHNKELHYCEICKKTLVAHMEKHKNNEDLKDEIRYLCSVCGKNYATLISLQKHLYSHNPSLVPDKTIRKYNRTKKRTTEIFKKYDCSFCDEKLSSLLGLQNHLKMHDENRKYKCEFCAVGYKRKEHLSAHINSKHTKIKKYYCSFCNKVFVSSTTKNSHEKSHLPDKNRCLYCSKTFKTYGRAKQHERTYHTKENVRVCVICNAVFTTYIQYRYHQVKKHSEEEIRTAKEKILTENLKSCTNESDNIEEEIMNDQRVDDS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-