Basic Information

Insect: Bombylius major
Gene Symbol: -
Assembly: GCA_932526615.1
Location: CAKOBF010001031.1:24298-25957[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.052 3.1 8.7 0.1 1 23 156 179 156 179 0.94

2 9 0.041 2.4 9.0 3.7 1 23 294 316 294 316 0.84

3 9 7.4e-07 4.4e-05 23.9 2.9 1 23 322 344 322 344 0.99

4 9 0.00016 0.0092 16.6 1.9 1 23 350 372 350 372 0.99

5 9 0.002 0.12 13.1 3.0 1 23 378 400 378 400 0.97

6 9 0.00043 0.026 15.2 1.0 2 23 407 429 406 429 0.97

7 9 0.0001 0.006 17.2 1.9 1 23 435 457 435 457 0.98

8 9 4.9e-06 0.00029 21.3 0.3 1 23 463 485 463 485 0.99

9 9 0.00091 0.054 14.2 4.5 1 23 491 513 491 513 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.052	3.1	8.7	0.1	1	23	156	179	156	179	0.94
2	9	0.041	2.4	9.0	3.7	1	23	294	316	294	316	0.84
3	9	7.4e-07	4.4e-05	23.9	2.9	1	23	322	344	322	344	0.99
4	9	0.00016	0.0092	16.6	1.9	1	23	350	372	350	372	0.99
5	9	0.002	0.12	13.1	3.0	1	23	378	400	378	400	0.97
6	9	0.00043	0.026	15.2	1.0	2	23	407	429	406	429	0.97
7	9	0.0001	0.006	17.2	1.9	1	23	435	457	435	457	0.98
8	9	4.9e-06	0.00029	21.3	0.3	1	23	463	485	463	485	0.99
9	9	0.00091	0.054	14.2	4.5	1	23	491	513	491	513	0.98

Sequence Information

Coding Sequence: ATGCCAAATTCATGTGCTGTGCTAGGTTGTAAATCAAATTATCGTTCAACAAGAAAACATTCTTCAAATGTACCAACATTTACATTTCCAAGAAATCCTGTAATAAATGATGCATGGATAAAAACAATTAAACGAAATAATTGGAAACCAAAAAAACATTCAACAATTTGTATTAAACATTTTCAAGAGAATGATTTCGTTAATTTTTCACGTTCAGGAAGAAAAAAATTAATATTAAAAAAAGATGCCATACCTTCAGTATTCTTTGATAAATTACAATTAGAAGAAATATATATTCAAAAACGAGATTTTCAAATGCGTTCAGTGATATTCCATGAAGATTTACAAAACAAAAATTATGAAGATTACATCGAAAATACAGAGTATATGCCAGATTACAATAAATTAGAAAAAACTACAAAAAAATGTGGGGAAATTTTCACAAATGGTTATGATTCTTTCAATTTTCTTTGTACAATTTGTGGGATTTTGTTAAAGGACATGAACGACTTTATGTCACATATAAAAGTTGATCACAAAAACACATTTCAAAATACATTAGAACATCCTGAAGCAGTTTTGGAAGAGTCAGAAATAAAGATTGAATCAGATCCGTTTGGTAGTGTTTTAGAAAACATTGAAGTAACTGTTGGTGCATTCAGTTTAGAATCTTATAATCAAGAAGATAACATAGATGATCAGAATGCAGTCAAGATGGATAGTGTTGATCAATCAAAAGATTCTATGAATAAAACAGTGTTAGACCCAACTAATAATAAATTTCTTATACATGATTTAACTGTTCAACCTGAAACACATAACAAAAATGAAGAACATAACAAAGATGAAATTAAAGAAACTGCtatagaaaaaaatccgttcaaatgtagatattgtgatcgtcattttaagcaacgctcagtaaaactcgaacatgaatacgtacatactggtgaaaaaccttataaatgcaataattgtggaaaaagtttccgaagaaaatctcgttatgcacaacatttaaaaattcatgaaaataaaaaagaatataaatgtgaaatatgcggtttcgcttttaattgtaaaccatatttaactgtacatatgcgacaacataaaaatgataaaagatataaatgtagttattgcgataaaacttttgttggctgtacaggtaaaataatgcatgaaagaactcatacaggtgaaaaaccaaataaatgtacagaatgtaatgatcgttttataacaagaggtaaattaaatgttcatatacgtaagatgcatactggtgaaagaccatttaaatgtgattattgtgataaaacattctttgatggtgaactaaaaagaaaacatttaagagttcatacaaaagagaaaccatatacttgtaatatatgtaatgcaacatttccattttctggtgatttaagaaaacatgaaagaattcattcaaatgaaattggttatgtttgtgatatttgtggaaaaggttttaaacaattttcagcattacattgtcataagaaaactcatgataaaaaTATGGTAGTTCTCGATCGGGTTAAAAACAAAGAGGACAATTTAATGAGATAA
Protein Sequence: MPNSCAVLGCKSNYRSTRKHSSNVPTFTFPRNPVINDAWIKTIKRNNWKPKKHSTICIKHFQENDFVNFSRSGRKKLILKKDAIPSVFFDKLQLEEIYIQKRDFQMRSVIFHEDLQNKNYEDYIENTEYMPDYNKLEKTTKKCGEIFTNGYDSFNFLCTICGILLKDMNDFMSHIKVDHKNTFQNTLEHPEAVLEESEIKIESDPFGSVLENIEVTVGAFSLESYNQEDNIDDQNAVKMDSVDQSKDSMNKTVLDPTNNKFLIHDLTVQPETHNKNEEHNKDEIKETAIEKNPFKCRYCDRHFKQRSVKLEHEYVHTGEKPYKCNNCGKSFRRKSRYAQHLKIHENKKEYKCEICGFAFNCKPYLTVHMRQHKNDKRYKCSYCDKTFVGCTGKIMHERTHTGEKPNKCTECNDRFITRGKLNVHIRKMHTGERPFKCDYCDKTFFDGELKRKHLRVHTKEKPYTCNICNATFPFSGDLRKHERIHSNEIGYVCDICGKGFKQFSALHCHKKTHDKNMVVLDRVKNKEDNLMR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00234867; iTF_00234270; iTF_00233950; iTF_00234878; iTF_00235302;
90% Identity: iTF_00234867; iTF_00234270; iTF_00233950; iTF_00234878; iTF_00235302;
80% Identity: iTF_00234867;