Bmaj011903.2
Basic Information
- Insect
- Bombylius major
- Gene Symbol
- -
- Assembly
- GCA_932526615.1
- Location
- CAKOBF010000252.1:586186-588146[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 10 1e-06 6e-05 23.5 0.5 2 23 189 210 188 210 0.97 2 10 6.2e-06 0.00036 21.0 4.4 1 23 216 238 216 238 0.98 3 10 6.8e-05 0.004 17.7 2.9 3 23 252 272 250 272 0.95 4 10 4e-05 0.0023 18.5 0.1 1 23 278 300 278 300 0.97 5 10 4.1e-06 0.00024 21.6 1.4 1 23 306 328 306 328 0.98 6 10 3.3e-07 2e-05 25.0 0.4 1 23 334 356 334 356 0.99 7 10 0.00029 0.017 15.7 0.5 1 23 362 384 362 384 0.97 8 10 1e-05 0.00059 20.3 1.5 1 23 390 412 390 412 0.98 9 10 0.00018 0.01 16.4 1.3 1 23 418 440 418 440 0.98 10 10 1.9e-05 0.0011 19.5 3.8 1 23 446 468 446 468 0.99
Sequence Information
- Coding Sequence
- ATGTGCGAAAACGAAAATTTAGATTTCAATAAAATCTGCCGAACATGCTTAAATCAAAGGAACGATATGAAACCTTTATACGGATCCTATCTTGATAAAATGCTTCTATCTGTTGGACAAATTGAATTACAAGAAGGAGATGGTCTACCAGAACATCTGTGTCTTCAGTGTGTGCTACAAATAAGCAGGGCATTTAGATTTCAACGTTTGTGTGTTAAATCAGACAGTATTTTAAGAGATCATCATATAAACAAAAAGAATGAAATTATTTTGGACAATTCAACAAAAGACGACAAAAATTCAATACAACAACCAATTATTGCTATTTCACAAACTGATATCACAATGGAAGAAAAATCTTCAGCTTTTGAAAGAAATTGTTCAGAATGCAATGACAATGGTACACCGAATGAAATTGAAGAACAAATTATCATGGAAAATAGAAAAATTGAATGTTCACAAGAATCCATAGACGACAAAGAATTTTATGATCTCCATTACGAAATGCAAAATTCAACATCATCAAATGAAAATTCAATAAAATACATTGAACAAAATTCAATTGAATGTCCGATTTGTAAAAAGATTTTTACAAAACGTAAAGCATTAAATCGTCATTTAAAAATTCATAATCCAATTaaatcacataaatgtgatatatgtgatatgaaatttacagaaagttcaaatttaaataaacataaaaaaaagcatactggtgaattacgtaataatgaaaataaatcacatttatgttcaatttgtggtaaaaattttaaatggtctagttcattatcacgtcatatgaaatatcatacaaaaaataaattatatttttgtccaaattgtccaaaatattatgctgaagctagctcattaaatattcatatgatgaatcatactggaataaaaccgtttaattgtagaatttgtaataaaaattttacaataatttcaaatttagaaaaacatttacgtacacataccaatgaaaaactatacacatgtccaatatgtgaaaaaaaattttcacaaagtggttacattcgaattcatatgagaattcatacgggagagaaaccatatatgtgtaatgaatgtggaaaatgttttgctggatcaaatattttggctgttcataaaagaattcattcaaatgaaagaccttatccatgtgatatttgtcataaatcttttagaaggcaacaaacagcaataattcatcgacgaattcatactggtgagaaaccttttatgtgtccaagatgtaaaaagggttttttaagtgctggacatttaaaaattcatttaagatctcatactggagagaaaccgtatacatgtgataaatgtgaaaaaaaatttgcaggaaaacacagtttgaaaATGCATTTGAAGACTCATACAAACAAATTAAGTGTAATTGGAGAAAATTTTTGA
- Protein Sequence
- MCENENLDFNKICRTCLNQRNDMKPLYGSYLDKMLLSVGQIELQEGDGLPEHLCLQCVLQISRAFRFQRLCVKSDSILRDHHINKKNEIILDNSTKDDKNSIQQPIIAISQTDITMEEKSSAFERNCSECNDNGTPNEIEEQIIMENRKIECSQESIDDKEFYDLHYEMQNSTSSNENSIKYIEQNSIECPICKKIFTKRKALNRHLKIHNPIKSHKCDICDMKFTESSNLNKHKKKHTGELRNNENKSHLCSICGKNFKWSSSLSRHMKYHTKNKLYFCPNCPKYYAEASSLNIHMMNHTGIKPFNCRICNKNFTIISNLEKHLRTHTNEKLYTCPICEKKFSQSGYIRIHMRIHTGEKPYMCNECGKCFAGSNILAVHKRIHSNERPYPCDICHKSFRRQQTAIIHRRIHTGEKPFMCPRCKKGFLSAGHLKIHLRSHTGEKPYTCDKCEKKFAGKHSLKMHLKTHTNKLSVIGENF
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- iTF_00234192;
- 90% Identity
- -
- 80% Identity
- -