Basic Information

Insect: Bombylius major
Gene Symbol: -
Assembly: GCA_932526615.1
Location: CAKOBF010001250.1:302053-305359[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 1.7e-06 9.9e-05 22.8 2.6 1 23 278 300 278 300 0.96

2 12 3.7e-07 2.2e-05 24.8 0.3 1 23 306 328 306 328 0.98

3 12 0.00046 0.027 15.1 3.3 1 23 334 356 334 356 0.97

4 12 5e-05 0.003 18.1 0.3 1 23 362 385 362 385 0.93

5 12 0.00061 0.036 14.7 1.7 1 23 393 415 393 415 0.96

6 12 2.3e-05 0.0014 19.2 1.9 1 23 426 448 426 448 0.99

7 12 1.5e-05 0.00087 19.8 4.0 1 23 454 476 454 476 0.99

8 12 0.00018 0.01 16.4 1.1 1 23 482 505 482 506 0.95

9 12 8.9e-07 5.3e-05 23.6 1.8 1 23 518 540 518 540 0.99

10 12 0.06 3.6 8.4 0.5 1 23 549 572 549 572 0.94

11 12 0.012 0.73 10.6 0.0 2 23 581 603 580 603 0.93

12 12 0.0029 0.17 12.6 2.5 2 23 609 630 609 630 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	1.7e-06	9.9e-05	22.8	2.6	1	23	278	300	278	300	0.96
2	12	3.7e-07	2.2e-05	24.8	0.3	1	23	306	328	306	328	0.98
3	12	0.00046	0.027	15.1	3.3	1	23	334	356	334	356	0.97
4	12	5e-05	0.003	18.1	0.3	1	23	362	385	362	385	0.93
5	12	0.00061	0.036	14.7	1.7	1	23	393	415	393	415	0.96
6	12	2.3e-05	0.0014	19.2	1.9	1	23	426	448	426	448	0.99
7	12	1.5e-05	0.00087	19.8	4.0	1	23	454	476	454	476	0.99
8	12	0.00018	0.01	16.4	1.1	1	23	482	505	482	506	0.95
9	12	8.9e-07	5.3e-05	23.6	1.8	1	23	518	540	518	540	0.99
10	12	0.06	3.6	8.4	0.5	1	23	549	572	549	572	0.94
11	12	0.012	0.73	10.6	0.0	2	23	581	603	580	603	0.93
12	12	0.0029	0.17	12.6	2.5	2	23	609	630	609	630	0.96

Sequence Information

Coding Sequence: ATGAGTATAGTAGATTTAAATGTTTGCCGAGTTTGTTTAATTCGTTTAAATGGCAAAAATTTTAAATCAATTAGAGATGATACAAATATATTGGATAGATTTCAACAATGTACGAGCTTAAAGATATACGATAATGATGGTTTACCATCTCATATTTGTGAACGTTGTAATGCACGTCTAAAAATAGCCCATGATTTTAGACGACAAGCAACATTATCTGATAGTCATTTACGATCATTTATAAATAAAATAAATTCACAATTTCAAGAAGTTGCAAATACAACAGTAACAAAAATCGAAACAATAACTGAATCTCAACTTTTATATGAATTTGGTTatgttgatgatgatgaaataaataaggataataaaaattataataatattcaaacattaccatcaataaatcaacaatatcataatgaagataataattttatatcagaaatacatagtgaaaataatcgaaatcaaacacaattaaatgatgatgaaatgcaaattgataataatgataatgatgaaacaaatattgataataatgatggtggtgataatagtgcatttattgaattaacatgtgatggtactggtgaagatgaagttgatggtgatgataataatgatgaagatgatgatgaaggtgaatggcaaacagaatcacaagatggttttacaAATGGACAAGAACAATCAACATCAAAATCATCACAAAATTATGTTTTAACTGAAATTGTTATTGATCCATTAAAAACATCTGGTACAATAACACAAGGTAAAGTACAACGTCGTTCAACAATACGTTCAAAAAGTAAATTAAAACATGGATCAcatatttgtgttaaatgtaataaagatttttcaacaagttcaaatttacaacgtcatttagatacacatgaaggtataaaaccatatatatgtaatgtatgtgaaaaaggatttacacaaaatggttcattaaaaaaacatatgctaatacatactggtgaaagaccacatgtttgtgatgtttgtggacgtggttttacacaacatacaacattaatatttcatatgagacgtcatactggtgaaagaccatattcatgtgatttatgtaatcgtgcttttcgtattaaagatgctctaaagAGACATATTGAGGATACACATACAGATAATATATCAAAAGTTCATATTTGTTCAATATGTAATCGTGGTCTTAAATCAAAATATTCATTACAAATGCATCTAGAAAGACATCGTGTTGATGATAATACTAATAAATTACAATATAAATGTGATGTATGTAATAAAATATTTAAATATCAAAATTCATTAGATGCTCATAAAAAACGTCATTATAATTTaaaattatttaaatgtaatcaatgtgataaacaatttacaagtaaaataaaatttaaatcacatattaaaatgcatacagaaataaaaccatatgattgtaatgaatgtggtaaatcatttcaattagaaaaacttttaaatgatcatattcaaTATTTACATCATAATAATACAGTTATAAGTAATAATTCGAAAATATTTCAATGTGAAGAATGCAAGAAAACTTATAAAATCAAAGAAAATTTAATTCAACATATGAAAACACATTGTAATGAAACATCACAAAAATTATATAAATGTGAAGATTGTGATATAGCATATGATGTATTACGTCGTTATAAATTACATCGTATTAGTAAACATGGTGAACAATGTGCAGATTTAAATCAATGTGATGAATGTAATATAGATTTTATAACTGGTAAAGATTTAAATGATCATATAGAAGCAGTACATGATACTATCGATGAAAAATGTACAGAATGTAATCAACATTTTACATCTAAAAAATTATATGAAGATCATGTATTAGAACATCAAATTGAATATCATCATGATTAA
Protein Sequence: MSIVDLNVCRVCLIRLNGKNFKSIRDDTNILDRFQQCTSLKIYDNDGLPSHICERCNARLKIAHDFRRQATLSDSHLRSFINKINSQFQEVANTTVTKIETITESQLLYEFGYVDDDEINKDNKNYNNIQTLPSINQQYHNEDNNFISEIHSENNRNQTQLNDDEMQIDNNDNDETNIDNNDGGDNSAFIELTCDGTGEDEVDGDDNNDEDDDEGEWQTESQDGFTNGQEQSTSKSSQNYVLTEIVIDPLKTSGTITQGKVQRRSTIRSKSKLKHGSHICVKCNKDFSTSSNLQRHLDTHEGIKPYICNVCEKGFTQNGSLKKHMLIHTGERPHVCDVCGRGFTQHTTLIFHMRRHTGERPYSCDLCNRAFRIKDALKRHIEDTHTDNISKVHICSICNRGLKSKYSLQMHLERHRVDDNTNKLQYKCDVCNKIFKYQNSLDAHKKRHYNLKLFKCNQCDKQFTSKIKFKSHIKMHTEIKPYDCNECGKSFQLEKLLNDHIQYLHHNNTVISNNSKIFQCEECKKTYKIKENLIQHMKTHCNETSQKLYKCEDCDIAYDVLRRYKLHRISKHGEQCADLNQCDECNIDFITGKDLNDHIEAVHDTIDEKCTECNQHFTSKKLYEDHVLEHQIEYHHD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00234211;
90% Identity: -
80% Identity: -