Basic Information

Insect: Bombylius major
Gene Symbol: -
Assembly: GCA_932526615.1
Location: CAKOBF010001250.1:306365-308940[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 12 1.3e-05 0.00075 20.0 1.0 5 23 322 340 319 340 0.94

2 12 6.9e-07 4.1e-05 24.0 0.3 1 23 346 368 346 368 0.98

3 12 0.00011 0.0063 17.1 4.3 1 23 374 396 374 396 0.99

4 12 5.8e-06 0.00034 21.1 1.1 1 23 402 425 402 425 0.97

5 12 0.00011 0.0064 17.1 1.9 1 23 433 455 433 455 0.97

6 12 8.7e-07 5.1e-05 23.7 1.8 1 23 463 485 463 485 0.98

7 12 4.6e-07 2.7e-05 24.6 1.1 1 23 491 513 491 513 0.98

8 12 1.8e-06 0.00011 22.7 1.6 1 23 519 542 519 542 0.97

9 12 4.2e-05 0.0025 18.4 1.7 1 23 550 572 550 572 0.99

10 12 0.00026 0.016 15.9 0.9 1 23 580 603 580 603 0.93

11 12 0.00036 0.021 15.4 0.1 2 23 612 634 612 634 0.97

12 12 0.17 10 7.0 1.2 2 23 640 661 640 661 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	12	1.3e-05	0.00075	20.0	1.0	5	23	322	340	319	340	0.94
2	12	6.9e-07	4.1e-05	24.0	0.3	1	23	346	368	346	368	0.98
3	12	0.00011	0.0063	17.1	4.3	1	23	374	396	374	396	0.99
4	12	5.8e-06	0.00034	21.1	1.1	1	23	402	425	402	425	0.97
5	12	0.00011	0.0064	17.1	1.9	1	23	433	455	433	455	0.97
6	12	8.7e-07	5.1e-05	23.7	1.8	1	23	463	485	463	485	0.98
7	12	4.6e-07	2.7e-05	24.6	1.1	1	23	491	513	491	513	0.98
8	12	1.8e-06	0.00011	22.7	1.6	1	23	519	542	519	542	0.97
9	12	4.2e-05	0.0025	18.4	1.7	1	23	550	572	550	572	0.99
10	12	0.00026	0.016	15.9	0.9	1	23	580	603	580	603	0.93
11	12	0.00036	0.021	15.4	0.1	2	23	612	634	612	634	0.97
12	12	0.17	10	7.0	1.2	2	23	640	661	640	661	0.96

Sequence Information

Coding Sequence: ATGAATATTAAAGTTGATATAAATGTTTGCCGAATTTGTTTAAAATCAGAACATGGTGTATCATTGTTTAATAATGATAGTAAATTATGTGAAAAATTTCAATTTAGTACACAAATAAAGATAAAAGAAAATGATGGAATGCCAATGATAATATGTCATCGTTGTGAAGCACGTCTTAAAATTACATATGATTTTAAAAAAGAAGCTTTAATATCGGATGCACGTTTAAGAGCATTCATTGATCGTGTTAATAATCAATTTAAATTAGTTGCAAATTCATCAAATGATTCTATACAAAAATTTGAAATATTTGATGAAAATGATGATGATGATGAAATGAAATTATTAATGGAAGCTGGTTATAAACCATTAGAATTTGAAGATGAACAACAACAACATCAACATCATCAACAACAAGAAGTAGAACTAGTAGAAGAAGAAGAACAACAACATCAAACAATAGTAACACAAGAAACAGATAtaacaacaatacaacatgaaccattaatttcaataatacaacaacaagatgttaaaacaattgaagaagattttcataatttaatacaaattgatgatgatccaggtaatgaatatgatgatatgcaacatattgatgaaaatgatgatgataataatgataatgataatgatgaagatgatgaacattgtgaagatgttattgatgataatgaacaattacaagataataatgaaataactcatatgaatacagtaagttcatgttcaacagtaattcctgttgaaacaacaacaacaacaacggcaacattaattgaaaattcaaatataaatgataataataacattgataataatACAATTCAAGTAGTACCAGTTGAATTAATTATAACTGAATATGAACAATCAACAATGACTATTGATTCATTAAAAAATAAAAATGAAAAATCAAGACATGAAAATCGTTCAAATATTTGTATTAAAtgtgatcgagattttagtacaaaaacaaatcttattcgacatatgatgacacatgatggtgttaaaccatttcaatgtaatatttgtggtaatggttttacacagaatggttcattaaaacagcatatgttaatacatactggtgaacgtccatataaatgtcatgtttgtaatcgtggttttacacaaagtaaatcacttgtattccatatgagacgacatacaggtgaaaaaccatatacatgtgaaaaatgtggtctaacatttagacaaaaagatggaatgaaGCGTCATGTTCTAATGAAACATTCTGGTGGTTCAACTGAAGTACATATTTGTTCAATTTGTAGTCGTGTTTTACAATcaaaatattcattacaagttcatatgagaagacatttatcacaatcagaattattatattcttgtgcaatatgtgaaaaatgttttagtacaaaaggttcattagaggtacatcaacgtcaacatactggagttaaaccatatagatgtgaacaatgtggaaaagattttccaagaaaaagttcattaatgacacatacaaaagttcatttagaagaaaaaccatttacatgtgaacattgtgataaaggattcgttcaaaagcatttattaattgcacatattcaaagtatacatactaataaaccagttaaagcatatcaatgtggtaAATGTTTTAAAAGTTTCGCAATAAAACGTAATTTACTTCAACATTTACGTAATCATAATAAAGAGAATATGACAATGTATAAATGTGATGAATGTAGTATTGCATTTAATACAAAACGTGCATTAAAATTACATCGTTTTAATGAACATAAAGAAACTGTATCAGATTTAAATGAATGTGATATTTGTAATATACCATTTGTATCAGTAAATGATTTAAATCAACATATGACAACAACACATGATAGTATTAATGAAAAATGTGATGTATGTATGGAACATTTTACATCACGTAAACTTTTAGATGATCATTTACTTGAACATGAATTAATAACAGTTAGTCAAACAACATAA
Protein Sequence: MNIKVDINVCRICLKSEHGVSLFNNDSKLCEKFQFSTQIKIKENDGMPMIICHRCEARLKITYDFKKEALISDARLRAFIDRVNNQFKLVANSSNDSIQKFEIFDENDDDDEMKLLMEAGYKPLEFEDEQQQHQHHQQQEVELVEEEEQQHQTIVTQETDITTIQHEPLISIIQQQDVKTIEEDFHNLIQIDDDPGNEYDDMQHIDENDDDNNDNDNDEDDEHCEDVIDDNEQLQDNNEITHMNTVSSCSTVIPVETTTTTTATLIENSNINDNNNIDNNTIQVVPVELIITEYEQSTMTIDSLKNKNEKSRHENRSNICIKCDRDFSTKTNLIRHMMTHDGVKPFQCNICGNGFTQNGSLKQHMLIHTGERPYKCHVCNRGFTQSKSLVFHMRRHTGEKPYTCEKCGLTFRQKDGMKRHVLMKHSGGSTEVHICSICSRVLQSKYSLQVHMRRHLSQSELLYSCAICEKCFSTKGSLEVHQRQHTGVKPYRCEQCGKDFPRKSSLMTHTKVHLEEKPFTCEHCDKGFVQKHLLIAHIQSIHTNKPVKAYQCGKCFKSFAIKRNLLQHLRNHNKENMTMYKCDECSIAFNTKRALKLHRFNEHKETVSDLNECDICNIPFVSVNDLNQHMTTTHDSINEKCDVCMEHFTSRKLLDDHLLEHELITVSQTT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00234188;
90% Identity: iTF_00234188;
80% Identity: -