Bmaj003678.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Bombylius major
Gene Symbol
ZFX
Assembly
GCA_932526615.1
Location
CAKOBF010000055.1:348254-352459[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 20 0.00044 0.026 15.2 0.7 2 23 133 155 132 155 0.95
2 20 0.0035 0.21 12.3 0.1 1 23 161 183 161 183 0.98
3 20 0.0073 0.43 11.3 1.4 3 23 192 212 191 212 0.99
4 20 0.045 2.7 8.8 0.7 1 20 218 237 218 239 0.95
5 20 3.5e-05 0.0021 18.6 1.5 1 23 272 294 272 294 0.97
6 20 2.1e-05 0.0013 19.3 1.9 1 23 300 322 300 322 0.97
7 20 0.00021 0.012 16.2 2.5 1 23 328 351 328 351 0.97
8 20 0.014 0.8 10.5 3.2 1 23 365 388 365 388 0.94
9 20 0.00024 0.014 16.0 1.5 1 23 510 532 510 532 0.98
10 20 5.3e-06 0.00031 21.2 2.9 1 23 538 560 538 560 0.99
11 20 3.5 2e+02 2.9 0.7 1 12 572 583 572 585 0.90
12 20 6.2e-05 0.0037 17.8 2.9 1 23 601 623 601 623 0.98
13 20 4e-05 0.0024 18.4 0.9 1 23 666 688 666 688 0.98
14 20 0.044 2.6 8.9 2.0 1 23 694 716 694 716 0.94
15 20 0.0002 0.012 16.3 0.8 1 23 722 745 722 745 0.95
16 20 8 4.7e+02 1.8 11.1 1 23 752 774 752 774 0.99
17 20 1.4e-08 8.5e-07 29.3 0.6 1 23 1088 1110 1088 1110 0.98
18 20 2.9e-05 0.0017 18.9 2.0 1 23 1116 1138 1116 1138 0.99
19 20 0.00019 0.011 16.3 0.2 1 23 1145 1167 1145 1167 0.98
20 20 0.066 3.9 8.3 3.4 1 23 1173 1195 1173 1195 0.98

Sequence Information

Coding Sequence
ATGAATTCTGTTGAAGGCATATTTCCACAACAAAAAACAACACAAAAATATGGGCCGCTTGAGAACACCGCAACTACAACAAAAACAAATGGTTTCAACGAAAAAGATGTTCAATTTTTAATGTCAAATAATTTTCTAATTCTTGATTTTGATAATTTTTTACATGGAAAATCTGACAAAAATTTACCAAAAATTACACCACCGATACAGCAATCAATTAATACAAATGATATTTCAATTCCTCTAGAGAAGCCAATGAATAACAATGATATTCCTGTTCAATTAGTTGAAAATAATAATAAAGAAGATAAAACAAATATTTCGGTAAATTCAAGAAGACGTAAAGGTAAAAATCCACGTAAAATTAATCAAAATGAATCAAAAAAGAATCCAACAAAATGTGATATTTGTAACGAAGTTTTTTATGATTTAAAATCATTAAAATCACATAAAAATAATGTACATATTTTTAAAAAACAATTTAAATGTAATGAATGTTTACAAGAATTTAATTTAAAAGTAAATTATATTGCTCATATTGCAATACATCAATCAGATTCAATAATTAAATTATGTCCAATTTGTAATTGTGAATTTCAACGACAAGCTAGTTTTTTAGGTCATTTAAAAACACATTTTATAAATGATAATTTCAAATGTGATAATTGTCAGGAAGAATTTGAATATAGAGAATATTTCGATAAACACCTGGAAAATTATCAAAATAAGACTTTAAAGGATGATGAGAATCTTGAAGAAATTATAAAACCAAAGAAACGATTACTTTCACCAAATAGCAAACGAGGTAGAAAATATGCTTGTAATACGTGTGATATGACGTTTACAAAACCAACATTTTTAAGACGACATCAATTATCACATGCAAATATAAAACCTTATGAGTGCCAAGAATGTAATCAAAAATTTACACAGAAATCATCTTTGGATAGGCACAAGTCTGTTCATACAGGAGACAAACGTTTCAAATGTCCAAAATGTTCATTCAGATTTTCACAAAAATCAAATCTTGTTTTTCATATAAAACGTGTACATTTTAATAGTTTATCAAATATAAAAATTCCAGAAAAAATATATCCATGTAAAGATTGTTCATGTGTTTTTCGTAAAATAAATTCATTAAGTCGTCATAGAACACAAATGCATTCAACAATAATTCAAAATTATTCAGATAATAATAATCAACGACAACAACAATTAAAAACAGATGATATTGATGAAATAACAATAAAAAATGTTATGAATGAATTAAAAAGTTGGCAACAATTTATGGAAAGTCAAGAGACATTATCAGAACCAGAATCATCAAATCAAAATTCTCCAATACAAACAACGGAAGAAATTCAAAATAATATAAATGAAATTTTATTAGAACAAGAAATTACTGAAAATCAAAATGAATCCTATGAAATTCATGAAGCTGTAAAAGATGTTGAAATTGTGGAAGAGAAAAAAGTTGAATTGACATATGAATTTCTTAAACATGAAATAATTGAGGGCATTAAATATTATATTTGTTTGTATTGTGATAAAAAATCAACAAGATCAAATACTATAATCAGACATCTTCGAACTCACACAAAAATTAAAAATTTCAAATGTGAAATATGTGGAAAACATTTCGGTTTAAAATTTAATTTGAAATCTCATATGAAAATTCATCAAAGTAAAAGTTTCTCAACACCAAGAAAATTATATCATTGTTATATTTGTTCAGAGCGTTTTAGTTCATTGAAACGTCGTGATTTTCATAATAAGTCAGTACATAACAACCAAAATATTTTTAAATGTACAATTTGTGATAATTCATTTAAGACATTTTCATATCTACGAATTCATACATTGAAACATTTAAATAATGAATTTACCGAAGATATTGATAAATCTTTACTAGAACCAATTTTTATTGGATCACCATCACTTGAACAAAAACTTAAAACCACTACCGATGATGATAATACATCATCAATAAGAAAATATCAATGCTTATATTGTGGATTGTCATTTAAAAAAATGTATGATTTGATAAAACATGAAGAAACTCATTCCAGTACAGAGTCTCACAAATGCATTGTTTGTGAAAAAAAATTTTCAAGTTCAGTGACCTTATATGCTCACAGTAAATTACATATTGATACGAAAAAATTCAATTGTTATTTATGTGATGCAAATTTTACAAGAAAAGCTAGTTTAAATCGTCATTTAGATGTTAAACATTCAGCAAAAGATAAATGTTTCAAATGTTGTTACTGTGAAAAAACATATCATTTGAAAGATCAATGTTATAGACATATAAAAACTCATATTAAAGTGTCAAATACAAATGTCGAATCTGTGAAAAAAAGACAAATAGATGATGGTGGCAGCGGAACAATTGAAATACAAAAACAATCAGAGATTCAGATATCATTAACGTCCAATGGGCAACAAAATCATGAAAATGAAATGAACTGTAACATAGAAATTGATTCAAACAATCAACAAAATCACAATTTGTTCATAAATAATATTTCAAATGAAGAAACGACTACGAGCACAGAGAACATTGAACTATACGACCATACTGTATCACAAGAAAATTTCACAATAATTCCATATAATACCAATGATACTTCTAGTTTATCAAATACAGTCAAAAATGATGAACCGTGTATCATATTACCCACTTCAAATGAATCTTTTATACATCAAAATACATATTATCCTGAAACAATAACACCATCAAGAGAACCTATCTGCTCAAAATTTCTCAAACTTGACAATGCTTTGTATGAAAATATCCAACTTCCAAAAAATATTATAATTGAGGAATTAGAAAGGAATACAAACTGTTCTACAGTAGCTGAAAATACACCAAAAATTCTCAAACTTGACAATGCTTTGTATGAAAATATCCAACTTCCAAAAAATATTATAATTGAGGAATTAGAAAGGAATACAAACTGTTATACAGTAGCTGAAAATACACCAAAAATTCTCAAACTTGACAATGCTTTGTATGAAAATATCCAACTTCCAAAAAATATTATAATTGAGGAATTAGAAAGGAATACAAACTGTTCTACAGTAGCTGAAAATACATCAAAAATTCCATTATTGACAAATAATCAAACTATTGTCGAAACGAATGATAAACAAGCAAAACCAATCAAAATTAAAAAATCCTCTAAACAACTGTCATCAATTTCTACAGTTTCTTCCAAtgaaaaaacaaataatacatcttctaaaggtaaatcacgttttagctgttcatattgtggtaaaggtttcaaaaaaccaagtgatttaatacgtcatatgagaatacatacaaatgataaaccatttaaatgtgatatatgttcaaaagcatttacattgaagaaaacacttgaaaatcataaaaacacacatgataataatcgtcggtatttcaattgtaatgtttgtggaaaaaaatatgcatcaaatgatatattaaatgtacatttacgaatacatactggtgaaaaaccatataattgtgaattttgttcaaatacatttcgtacacttggacatcgtaatgctcataaaaaagttcatCAAAAAGAAAATTTAAAAATGATGAATTTTAGAAAAAACAGTTAA
Protein Sequence
MNSVEGIFPQQKTTQKYGPLENTATTTKTNGFNEKDVQFLMSNNFLILDFDNFLHGKSDKNLPKITPPIQQSINTNDISIPLEKPMNNNDIPVQLVENNNKEDKTNISVNSRRRKGKNPRKINQNESKKNPTKCDICNEVFYDLKSLKSHKNNVHIFKKQFKCNECLQEFNLKVNYIAHIAIHQSDSIIKLCPICNCEFQRQASFLGHLKTHFINDNFKCDNCQEEFEYREYFDKHLENYQNKTLKDDENLEEIIKPKKRLLSPNSKRGRKYACNTCDMTFTKPTFLRRHQLSHANIKPYECQECNQKFTQKSSLDRHKSVHTGDKRFKCPKCSFRFSQKSNLVFHIKRVHFNSLSNIKIPEKIYPCKDCSCVFRKINSLSRHRTQMHSTIIQNYSDNNNQRQQQLKTDDIDEITIKNVMNELKSWQQFMESQETLSEPESSNQNSPIQTTEEIQNNINEILLEQEITENQNESYEIHEAVKDVEIVEEKKVELTYEFLKHEIIEGIKYYICLYCDKKSTRSNTIIRHLRTHTKIKNFKCEICGKHFGLKFNLKSHMKIHQSKSFSTPRKLYHCYICSERFSSLKRRDFHNKSVHNNQNIFKCTICDNSFKTFSYLRIHTLKHLNNEFTEDIDKSLLEPIFIGSPSLEQKLKTTTDDDNTSSIRKYQCLYCGLSFKKMYDLIKHEETHSSTESHKCIVCEKKFSSSVTLYAHSKLHIDTKKFNCYLCDANFTRKASLNRHLDVKHSAKDKCFKCCYCEKTYHLKDQCYRHIKTHIKVSNTNVESVKKRQIDDGGSGTIEIQKQSEIQISLTSNGQQNHENEMNCNIEIDSNNQQNHNLFINNISNEETTTSTENIELYDHTVSQENFTIIPYNTNDTSSLSNTVKNDEPCIILPTSNESFIHQNTYYPETITPSREPICSKFLKLDNALYENIQLPKNIIIEELERNTNCSTVAENTPKILKLDNALYENIQLPKNIIIEELERNTNCYTVAENTPKILKLDNALYENIQLPKNIIIEELERNTNCSTVAENTSKIPLLTNNQTIVETNDKQAKPIKIKKSSKQLSSISTVSSNEKTNNTSSKGKSRFSCSYCGKGFKKPSDLIRHMRIHTNDKPFKCDICSKAFTLKKTLENHKNTHDNNRRYFNCNVCGKKYASNDILNVHLRIHTGEKPYNCEFCSNTFRTLGHRNAHKKVHQKENLKMMNFRKNS

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
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