Bdis002952.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Bombylius discolor
Gene Symbol
L
Assembly
GCA_939192785.1
Location
CALNDV010000167.1:335902-351693[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 18 6.8e-06 0.00039 20.7 1.7 1 23 231 253 231 253 0.98
2 18 0.54 31 5.3 5.7 1 23 259 281 259 281 0.98
3 18 2.9e-07 1.7e-05 25.0 3.1 1 23 287 309 287 309 0.99
4 18 2.4e-05 0.0014 18.9 0.2 1 23 315 337 315 337 0.98
5 18 1.1 62 4.3 0.3 10 23 404 418 395 418 0.87
6 18 0.0042 0.24 11.9 0.3 2 23 452 474 451 474 0.96
7 18 0.048 2.8 8.6 0.3 1 23 580 602 580 602 0.95
8 18 0.01 0.6 10.6 1.8 2 23 612 634 611 634 0.94
9 18 0.00034 0.02 15.3 0.9 1 23 642 666 642 666 0.91
10 18 7.5 4.3e+02 1.7 0.1 1 19 671 689 671 691 0.82
11 18 0.12 7 7.3 0.9 1 23 701 724 701 724 0.98
12 18 0.0027 0.16 12.5 2.1 1 23 758 780 758 781 0.96
13 18 0.0019 0.11 12.9 4.9 2 23 983 1005 982 1005 0.97
14 18 0.15 8.6 7.0 0.1 1 23 1011 1033 1011 1033 0.92
15 18 1.3 75 4.1 1.0 2 23 1041 1062 1040 1062 0.96
16 18 2.1 1.2e+02 3.4 0.2 2 23 1156 1177 1156 1177 0.95
17 18 0.44 25 5.5 0.4 1 23 1187 1210 1187 1210 0.94
18 18 0.037 2.1 8.9 0.4 1 23 1217 1239 1217 1239 0.96

Sequence Information

Coding Sequence
ATGGCATTAAAAATGCTTTATCGTGGTCCTAGTTCGAGATTAGAAACATTAATTGAAAAAATACAACAAACCAAAGAAGTTGGAAGTGATTTATATTCAACTCATACCTCATCAAGTTATTCACCCTCAATGTCAGAAGGagcagcaacaccaaattcattattaaattcacaccaccatcaacaccacctacatcataataatgagcatcattcacaagaagtaacagcacatgaaggtgatgcttgtgataatggtgatggtgaaggtggtactaatagtcgttacagaaaacgtcgtcaacttaataatgatgatgatgatgttaatgttgatgaagatgtaggtggtattaaaataacagcaaatggatgtttaaaaaattctgatggtattaataataataatgatgataatcacaatggtgataatggtggtggtgatgatgaaattgttgattcaaataatgaaaaaagggttattgttgaaaaaataataaaatatcgtcgtaatcataaaaataataatgatgatgagattaataatgtttgtaatgatgttgttgataataatggaatattatcaacaaaattacgtaaaattgatagagatttagttaaaacagaaaagatgacaaGTAACAGTATTAAATCTGGTACACAAACAACAGTAAATACATCAGATGGTTCATATCAATGTCAATTTTGTGATAAATCATTTCCACGTCTTGGTTATCTTAAAAAACATGAACAGAGTCATGCAGAACATCTACCTTTTAAATGTGAATACTGTGCAAGATTATTTAAACATAAGCGTTCACGAGATCGTCATACAAAATTACATACAGGTGACCGTCGTTACAGATGTCCACATTGTGAAGCAGCATTTTCAAGAAGTGACCATCTTAAGATTCATATGAAGACACATGATAATCAAAAACCATTTCAATGTACCGTTTGTAATCGAGGATATAATACAGCAGCAGCATTAACATCACATATGCAAAATCATAAGAAACAAGCAGCACTTTTAGGAACTGGTCTGGGTCCCCTAAATTATAGTCCTCGTTCGACTGGTTCTGGTTCAAGTAATGGAAGTTTCAATCATAAGAGACGTTATGCAACCGCTGATAATAGTCCAAATCGTATTGATTACCGAAAACATGGACGGAATTCTTTTATATCATGTATCTATTGTACTAAATCAGATTTTACATCTTTAGAACAACTTAACAATCATATTCAATCAATGCATGAAAATAATCAACAACCTACAAAAGACACTCTCGCAATCAATCATCCTGCTGCTGCTGCTGTTGCTGCTGTTTCAAATGTTTCATCAATATTTCAATTATCTTGTGAATATTGTACTATGAAATTCCCAAGTATACCAGCAATGTTTCAACATATGAGAACAACACATATTGATCGTTTAACAAGTCCAAATTCATATTTTGAACATTTTAATAGACTTGCAGCATCTGGTACATTTAGTCCAAGACTTGCAACAACAACAACAACAGCAACTACAAATCGTTTTGGAGAAGAAACAAATGGAACAAAACAAATAAAAACTGAAGAACCTAGTCCAAAATTAATTGAAAGAAATTCATTGGAAACAGAAACAAAAGATGAAGAACAAATTAGTCCAACAGATTTAAGTCAACCAAAAAGACGTTCACAAACACCATCATTACAAATTCAATCAGAACCTTCAGTCATTGAAAAACCAGGAACATTTTTATGTAATCAATGTAATGCTGGTCTTCCTGATTTCGATACATTCCGTGCACATTTAAAAACTCATATAACACAAGGAATGACAACAAATTTGATATGTCATCATTGTGGAATTTCATCATTCCGAGATCAAACCGAATATGAAAGGCACATTATATCACATTTTCTATTAACCAGTTCTGAATATAATTGCTCAAATAATTGTAATAAAGTTTACACGAAACCAGATGATTTACAAAAGCATTTATTTGAAAATCATGTTCTAACTTTATACAAATGTTCAATATGTTCAGATTTATTTGATACAAAAGTTGCAATTCAAGTACATTTTGCATGTATTCATTCAACAGAAACAAAAATATTTCGTTGTTCAGCTTGTATGGAAACATTTCGTATTGAAAAAGATTTTATATCTCATATAAGAACACGTCATTTAAATACAACAAATACAACAATTCAATGTATGTTTTGTCGTGCAATTTGTTCATCTGAATTAGAAATGCATTTTCATTTAGCAGCACATGCACGACAATTTCGTTGTCCAGCATGTCCTGAAACATTTCATGTTGAATTCCTTTTAGATCGTCACATGCAAACGCATCATTCACAAAAGGATAATTCACAAACTGTATCAACATATCATTCACATTATGGTAAAACAACAACACAAACAACATCCACAACACCACAATCATCGAATAACAACAATAACGTCCTTGATTATCATGCTTTTGCAACAGCAACCGGAAAAAATCTTTTCCAATTGCCTGGAACAAAATTTTATAATCCTATACAAGTTGATACAAATTCAAATAAACATGCTGCATTCATGTATGGATTAGGACAACGTTATTTTGATACAAGTAAAACTTTAATGGACATGTacaataattatcatcatcaacaacaacaacagcatcaacaggataaagtcgattcaaattatttcatcaacaattcaaacaacagcagcaacaacaacagtaataatttcgataaccatcatcatcatcgAACAAATAAAATTCAAAATAACACCAATAAATTATTATCATCATCATCATCATCGAACACTGATAGAATACAAAATAATACAAATAACAGTGGTTTCAGTTGTGGAATATGTGAAAGAAATGATTTTCGTACTGAAAATGAAGTACATTCACATCGTAAAATTGTTCATAATTTAAAAACTGGTGTTAGTTTAAAATGTGCCTATTGTAATGGAAATTTTAAATCACGTAATGAATTAGAACATCATATGAAAACATGTCATAATTCAACTGGTAAACATAAATGTTTAATATGTGATGAAATATTTCCATCACCAGCAATATTAGCTGAACATAAATTACAACATTCAAAAGTTGGACAATCTGGTAAATGTTCACATTGTTCATTTGCATTAAATGATATTAATGCATTTAAATCACATTTATCTGAACATAATGTATCACAAGAAGGACAAATACCAGTTCAATGTATTTGTTGCCGGCAAACACTTAATTCAGATTTTGAAATAAGTCTTCATGCAAAATTTCATACAAAATCATCAAATTTACAAGAAAATGTATGTGCTTTATGTTTAGAACCGATATCAATAACAACAACAACAACATCAGAAACAGCAAAAGTATGTGAAAAATGTTGCCGTAAACATAATTTAACAACAAAATTTAATATACGTTTTGATAATGTTAATTCACGTTTAACATTAATTGAAAATCGTTGTAATTTATGTAAAATGATATTACCAAATTTACAACGTTTACAAGAACATTTAATTGAACATACATTTATTGGTTGTGAAGAAAGAGGTTATTCATGTTATATTTGTTCATCAGTATTTACAGTACCAGCTGGTTTATTATGTCATATGAATGAACAACATGGACAAAATTCAAGACCATATGATTGTAATTTATGTACAGAGAAATTTTTTTTTAGAGCTGAATTAGATAATCATTTAATTGAACATGAATATAATAATAATAAAAATTCAAATAATAATTTAATTAATAATAATTGTAATATTAATTTAACACATGATAATAATGATGATAATAATATGAAAAAATCGAAAAATGATGAAACGATTAGAGAAAAAAATTCATTTAATGAAAATAATAATACTGCAGCAAAAGAAACAATTAATAAAATATCGAAATTAGAAGTTAAAACAGAAATTTTAGATGATGTGAGACCAGATGATGATGAAGAATATATTGAAGTTGAAAAAGTTGCAGAAACTATTGATAATGTAAATAGAGATGATAGTAAAGATGAAAATTAA
Protein Sequence
MALKMLYRGPSSRLETLIEKIQQTKEVGSDLYSTHTSSSYSPSMSEGAATPNSLLNSHHHQHHLHHNNEHHSQEVTAHEGDACDNGDGEGGTNSRYRKRRQLNNDDDDVNVDEDVGGIKITANGCLKNSDGINNNNDDNHNGDNGGGDDEIVDSNNEKRVIVEKIIKYRRNHKNNNDDEINNVCNDVVDNNGILSTKLRKIDRDLVKTEKMTSNSIKSGTQTTVNTSDGSYQCQFCDKSFPRLGYLKKHEQSHAEHLPFKCEYCARLFKHKRSRDRHTKLHTGDRRYRCPHCEAAFSRSDHLKIHMKTHDNQKPFQCTVCNRGYNTAAALTSHMQNHKKQAALLGTGLGPLNYSPRSTGSGSSNGSFNHKRRYATADNSPNRIDYRKHGRNSFISCIYCTKSDFTSLEQLNNHIQSMHENNQQPTKDTLAINHPAAAAVAAVSNVSSIFQLSCEYCTMKFPSIPAMFQHMRTTHIDRLTSPNSYFEHFNRLAASGTFSPRLATTTTTATTNRFGEETNGTKQIKTEEPSPKLIERNSLETETKDEEQISPTDLSQPKRRSQTPSLQIQSEPSVIEKPGTFLCNQCNAGLPDFDTFRAHLKTHITQGMTTNLICHHCGISSFRDQTEYERHIISHFLLTSSEYNCSNNCNKVYTKPDDLQKHLFENHVLTLYKCSICSDLFDTKVAIQVHFACIHSTETKIFRCSACMETFRIEKDFISHIRTRHLNTTNTTIQCMFCRAICSSELEMHFHLAAHARQFRCPACPETFHVEFLLDRHMQTHHSQKDNSQTVSTYHSHYGKTTTQTTSTTPQSSNNNNNVLDYHAFATATGKNLFQLPGTKFYNPIQVDTNSNKHAAFMYGLGQRYFDTSKTLMDMYNNYHHQQQQQHQQDKVDSNYFINNSNNSSNNNSNNFDNHHHHRTNKIQNNTNKLLSSSSSSNTDRIQNNTNNSGFSCGICERNDFRTENEVHSHRKIVHNLKTGVSLKCAYCNGNFKSRNELEHHMKTCHNSTGKHKCLICDEIFPSPAILAEHKLQHSKVGQSGKCSHCSFALNDINAFKSHLSEHNVSQEGQIPVQCICCRQTLNSDFEISLHAKFHTKSSNLQENVCALCLEPISITTTTTSETAKVCEKCCRKHNLTTKFNIRFDNVNSRLTLIENRCNLCKMILPNLQRLQEHLIEHTFIGCEERGYSCYICSSVFTVPAGLLCHMNEQHGQNSRPYDCNLCTEKFFFRAELDNHLIEHEYNNNKNSNNNLINNNCNINLTHDNNDDNNMKKSKNDETIREKNSFNENNNTAAKETINKISKLEVKTEILDDVRPDDDEEYIEVEKVAETIDNVNRDDSKDEN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-