Basic Information

Insect: Bombus waltoni
Gene Symbol: mecom-b
Assembly: GCA_014737395.1
Location: JACXII010000032.1:7466913-7477306[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0013 0.1 13.0 0.3 2 23 122 144 121 144 0.96

2 9 0.12 9.4 6.8 0.1 1 23 151 174 151 174 0.93

3 9 1.3e-05 0.001 19.2 1.7 1 23 180 207 180 208 0.93

4 9 3.7e-06 0.00029 21.0 2.6 1 23 214 236 214 236 0.95

5 9 2.3e-05 0.0018 18.5 5.0 1 23 242 264 242 264 0.99

6 9 0.00045 0.035 14.4 0.7 2 21 272 291 271 292 0.95

7 9 5.3e-09 4.2e-07 29.9 1.2 1 23 647 669 647 669 0.99

8 9 2.8e-07 2.2e-05 24.5 1.7 1 23 675 698 675 698 0.97

9 9 7.9e-06 0.00062 19.9 3.4 1 23 704 726 704 726 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0013	0.1	13.0	0.3	2	23	122	144	121	144	0.96
2	9	0.12	9.4	6.8	0.1	1	23	151	174	151	174	0.93
3	9	1.3e-05	0.001	19.2	1.7	1	23	180	207	180	208	0.93
4	9	3.7e-06	0.00029	21.0	2.6	1	23	214	236	214	236	0.95
5	9	2.3e-05	0.0018	18.5	5.0	1	23	242	264	242	264	0.99
6	9	0.00045	0.035	14.4	0.7	2	21	272	291	271	292	0.95
7	9	5.3e-09	4.2e-07	29.9	1.2	1	23	647	669	647	669	0.99
8	9	2.8e-07	2.2e-05	24.5	1.7	1	23	675	698	675	698	0.97
9	9	7.9e-06	0.00062	19.9	3.4	1	23	704	726	704	726	0.99

Sequence Information

Coding Sequence: ATGCTGGAGCGGCAAGCAACACTGGGTGATGAGAGGGCGATATCCGTTCGTACAGCTGGAAGTGGAGTCAGGGGATGGTTGGACGCATCCCACGAAACAAATAATTGGTTGAAGTATGTTCGAAGCACTAGCAGTCCGCACACCGTTAATATGCGACACGTGCTTATTGGTGGACAGATGGTGTACGAAGCGGTGCGGGACATAGCGGCGGGTGAAGAGCTGCTTCTCGGTGTTCGAGAGCCTCTCCAACTTCAGGATATGCTTGGCGAAAATACTACCGAGGACAGAAGCGATCGAGAGACCGCCTCGCAACATAGTGGGACCGTAGACGAAGATAAAGAAGACGAGGAGGAAGGGGAAACCAGATGCCCCGTCTGCGACAAACCGTTTCAAGATATTGAACTATTGGACAGTCACCTGATAACGTGTCACAGATATCCAGCGGAACAGCATCGCTGCGACAATTGTCCCCGTGCGTACGCCTGGCGACCACTGTTGGTTCGTCATCGTGCGATCGTTCACGGCGATCTTCGAAACTATCCCTGTGAGAACTGTCCGAAGTCGGACAAACCGCAGGTCTTCACGGACCCGTCGAACCTCCAGCGTCACATCAGGACCCACCACGTGGGCGCGAGGAGTCACGCGTGCACCGAATGCGGAAAGACGTTCGCCACCAGCTCCGGTCTCAAGCAGCACACTCATATCCACAGCAGCGTGAAACCGTTCCAGTGCGAGGTCTGCTTCAAGGCATACACGCAGTTCTCGAACTTATGCCGACACAAACGCATGCACGCCGATTGTCGTATGCAGATCAAGTGCGTTAAATGCGGACAGTCCTTCAGCACGGTCACCTCGTTATCAAAGCATAAGCGATTTTGCGATTCGACACCGCCGACCGGTCCACCTGGCGCTATGCCTCAGTTACCAACCCCAGCGCCGAGTCCTTTTCTGGTCTATCCCAGACCTCCGGTCAGTCTACCAGGAGGTTTACCTTTCTATCCACCGAGTTTGATGGGACCCTATCCGGGAATTTTTCCGAACGCTCCTAACTTTTTGAACACTCCGCTCTTGTTCCCGCCGAAAGTCGAGGAAGCTGAGAAAAGGAGCGACAGTCCGAAGAAAGAGCGATTCACCCCGCCGAGGGTGCTGCCGCAGCATAGTAAAGTATCTCCATCCACTGCGGAGGAGGCTACGTCCTCGTTCAGACCATCCCCAGCTAGGCCGCCTGTCCAGCCAACTCCCGAGAGCGATGACGATCCCTCTAAGAAACGGGAGATCAACAGAAACAACGAGAAAAAGACGGATTCTGAACATGCCCCGGCAACCACGAACGAAGAGACGACGGACCAACCTTTAGATCTGAGAGTCCAAACGAAGAAGCAACGAACGAATTCGAACATCGCCGAGAGAAAGAGTCGTAGCCCGTCACCAACGCCAGCGCCGATGGAGGAAGCACCACCTCCTCCAGATCCTCCAAAACCTGAGGAAGAGACGCCTGTGCCAATGGAGGTCGATACCAAGGATGTGCCCAACAGTCCGCAGCTGAGAACCAGTCTACCCACGGAACAACCACCTACCACCACACCACCGCACATGGCGTATCCCAGACCGATTCATCCAATGTTGCTGGAGGCCATGTATCGCGGACCAACCAGTTCCTTCCCAGGATTTCCAGGTGGACCACCGCCTCCTGGAGGTGCAACCCCGGAATCCAGACTGCTACCACCGCTACCACCGTTTGGACCACCGCGTGGGCTTCCTTTTTTAGGGACATTTATGAACGGGCTCAGCGGCGCTAGGCCAGGAGGTGGAGGATTCGACCTGCTTGCCAGGCCGCCGCTGGGACCGTTCCCCGGCGTGAAGCCGTTCCAAGAGGCTGTGATCGCGCCCCATCACCATCATCACCATCATCACGCCCACGGCAAAATGAAAGACCGATATTCCTGCAAGTTCTGCGGGAAGGTGTTCCCCAGATCCGCTAATTTGACCAGACACTTGCGCACACATACCGGCGAACAACCTTACAAATGCAAGTATTGCGAGCGGTCCTTCAGCATCTCCAGTAATCTTCAGCGGCACGTGAGGAATATCCACGACAAACAGAGACCTTTCAAGTGTCCACTTTGCGAGAGATGCTTCGGCCAACAGACAAATTTAGACAGACATCTGAAGAAGCACGAAGCCGACGATGGTAGTGGCGTTGTTTCCGTGGCGGATTCACCTGGAAGCAGCAACGAAAACGAACGAGAGGACACGTACTTCGACGAAATCAGATCGTTCATGGGAAAGGTGACTTACGGTGGCGAGGCTGGCTATGGATTACCGCCTCACCCGGCCTATTTACCTAGTCGACTTCACGAGATGCACGAGTCCAAGATGGAAACGGAGTACGACGAAGACGAGGATAGCGAGGAAGGAGTCTCCCCTTTGGACGAAACGGATGGCTTGTCACCCGCAGAGGCTAAAGAATCCACTCCACCACCGCAATACGATCTGAAGCTGAGGGAGAAGCAGGAACTGCTCAACAACAACACGGCCGAGCCCGTCATCGAGATTTCCACATAG
Protein Sequence: MLERQATLGDERAISVRTAGSGVRGWLDASHETNNWLKYVRSTSSPHTVNMRHVLIGGQMVYEAVRDIAAGEELLLGVREPLQLQDMLGENTTEDRSDRETASQHSGTVDEDKEDEEEGETRCPVCDKPFQDIELLDSHLITCHRYPAEQHRCDNCPRAYAWRPLLVRHRAIVHGDLRNYPCENCPKSDKPQVFTDPSNLQRHIRTHHVGARSHACTECGKTFATSSGLKQHTHIHSSVKPFQCEVCFKAYTQFSNLCRHKRMHADCRMQIKCVKCGQSFSTVTSLSKHKRFCDSTPPTGPPGAMPQLPTPAPSPFLVYPRPPVSLPGGLPFYPPSLMGPYPGIFPNAPNFLNTPLLFPPKVEEAEKRSDSPKKERFTPPRVLPQHSKVSPSTAEEATSSFRPSPARPPVQPTPESDDDPSKKREINRNNEKKTDSEHAPATTNEETTDQPLDLRVQTKKQRTNSNIAERKSRSPSPTPAPMEEAPPPPDPPKPEEETPVPMEVDTKDVPNSPQLRTSLPTEQPPTTTPPHMAYPRPIHPMLLEAMYRGPTSSFPGFPGGPPPPGGATPESRLLPPLPPFGPPRGLPFLGTFMNGLSGARPGGGGFDLLARPPLGPFPGVKPFQEAVIAPHHHHHHHHAHGKMKDRYSCKFCGKVFPRSANLTRHLRTHTGEQPYKCKYCERSFSISSNLQRHVRNIHDKQRPFKCPLCERCFGQQTNLDRHLKKHEADDGSGVVSVADSPGSSNENEREDTYFDEIRSFMGKVTYGGEAGYGLPPHPAYLPSRLHEMHESKMETEYDEDEDSEEGVSPLDETDGLSPAEAKESTPPPQYDLKLREKQELLNNNTAEPVIEIST

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01539779;
90% Identity: iTF_00118172;
80% Identity: -