Basic Information

Insect: Bombus sibiricus
Gene Symbol: zfh1
Assembly: GCA_014737505.1
Location: JACXIM010000175.1:3253572-3300172[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 1 1.2e+02 3.8 1.8 2 23 92 114 92 114 0.90

2 7 8e-05 0.009 16.8 0.6 2 23 133 154 132 154 0.96

3 7 5.2e-06 0.00058 20.5 7.8 1 23 163 185 163 185 0.99

4 7 0.0001 0.012 16.4 1.6 1 21 191 211 191 212 0.92

5 7 0.0002 0.023 15.5 4.5 1 23 657 679 657 679 0.94

6 7 6.6e-05 0.0073 17.1 7.1 1 23 685 707 685 707 0.98

7 7 0.0014 0.15 12.9 4.3 1 21 713 733 713 734 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	1	1.2e+02	3.8	1.8	2	23	92	114	92	114	0.90
2	7	8e-05	0.009	16.8	0.6	2	23	133	154	132	154	0.96
3	7	5.2e-06	0.00058	20.5	7.8	1	23	163	185	163	185	0.99
4	7	0.0001	0.012	16.4	1.6	1	21	191	211	191	212	0.92
5	7	0.0002	0.023	15.5	4.5	1	23	657	679	657	679	0.94
6	7	6.6e-05	0.0073	17.1	7.1	1	23	685	707	685	707	0.98
7	7	0.0014	0.15	12.9	4.3	1	21	713	733	713	734	0.96

Sequence Information

Coding Sequence: ATGAGCATGACTCTCGTCCGCAATACGTTCAAAGGTTGCAGCGAGGACGAGGCAGCAGGTGTCGTGAACGCGGAGGTGGGCGGAGGTTGCGCGGCCGGGGCGCCAACCACAGGAAGTGGCGTTGGAGGTGGTAGCGGCACAGGTAGCGAAGCCGGTGGTGGTGGTGGAGGCGGTGGTGGAGCAGGAACAGGAACAGGAGGAGGCGGAGGAGGCGTCCGTGGTGGCGGCGGCAGCGGTGGCGGCGAGGGCGGATCGACGAAGCAGGGTGGCGAGAAGTGTCCCCAGTGCGGCTTCCTCTGTCGGGACGTCCACGTGCTTCAGCTCCATCTCGAGGACACGCACAAGACCCCGTACGCCATCGACAAGAACGATCTCAACGCTCAATTCCCTCAAGTGTCCTGCAGGGTGTGCAGCAAGACTTTTGCTAACGTCTACCGACTCCAGAGGCACATGATCAGCCATGATGAGAGTGCCGTGCTTCGTAAGTTTAAGTGTCCCCATTGCGAGAAAGCCTTCAAGTTTAAGCATCACCTCAAGGAGCACCTCCGCATTCACAGCGGTGAAAAGCCATTCCTATGCAACAACTGCGGCAAGCGCTTTTCCCATTCGGGCTCGTATTCGAGTCATATGACCTCGAAGAAGTGCCTGATAGTAAATTTAAAAAAATCCAGGCATACGAATGTGAGCAACGTGGATCGCGGGCCGAAAAAGGCGCAACAACCCCTGCCGCCGGGGCGGCGCGAGGTCGATCTGCTTGCGGCGAATAATAACACTTTCCTCCCTATTCTGCCGAAGCTTTCACCCTCGGATTATCAGGAGATACAACGGGAAGGAGCGGGTATTTACGATATGCCGACCCTTCTGCCACAAATGATGGGCTTCGGCAGCTACTTTCTGCAAGCATCTTTGGGCAAGATCTTAAATCAGCTACATTCCAAGAGATTGGACGAGGTAGCCGAGAAATTCGAATCTCATCGGGAGCTCATGAGCCCGTCGACGGCGGACTCTGAGGGCACGGAAGGTACAGAGGGTAAAGAATCACCAGCACCGACCGATCCTCAGGGTCTTGACGCGGTTCGACGTATCCTTGAAACGGTGAACACCTCCGTCACGAAGCAACTGCTCGAGGCGAACGTGAGGAAATTGTCCACGTCGCCGGCCACGATGAAACGAGAGTTCGAGGAGGATTATCAAGATCAAGACAGCGAGATGTCCAGCGAGATGGCACATTATCCAGACTGGTCAGCAGCGGATCAATATGATTCGCAGAGTGAAGGTTTGGCGGCGAAACTCGAGGACGTGAATCAACCCAGTGCGAAATCAGGTTACAAGAGAAAAGCGGAGGATAGCTCGGAGGCGGACTCGGAGGACGAGGAGGATGGTACACAGACGCACAATGATAACGGAAGGAGAGTCAGGGCTAGATCGTTGATAGACGATGAGCAATTGGCTGTTCTCAAGGGTTACTATGCCATTAATCCTCGACCCAAGAAGGAGGAGATCATCATGATCGCCAATTACATCAATTTTCCTACTCGTGTCGTACAGGTTTGGTTCCAAAATTCCCGAGCGAGGGACCGACGAGAATCGAAGATACCACCTCTAGTACCATTAGCAAATCCGACCAGTCAGACCGCGTACGAACAACCATTAGATTTATCGAAGAAAGAAGCTCTCACAGAGACGGCGTGCAAAGACAGTGAAACTATCTGTGCAAAATTCACATCATCGTCTCCCGTTGAACCGAAAAACGATAATGCGCCGTCGCATAATCAAGACGCGGATGATTTGGAGGATTCGCCACTCGTTATTGACGAAGAGACCACCGATTCTGTAGAAACGAAACGTACGGCCCCGATGGGGGGAGAAATTGTTCCGAAGAGTCAACCTCAAACAAATGTAAAGAACGAAAGTGAAAACACGAGTCAACCAGAGGCTTCGCCAGCAGCGGAGATCGAGCAGGGTGTCTACTTCTGTGATCGGTGTGACAAAACATTCTCCAAGCACAGTTCCCTAGCAAGACACAAATATGAACATTCCGGGCAAAGGCCGTACAAATGCGTGGAGTGCCCAAGGGCGTTCAAGCACAAGCACCATCTGACCGAACACAAGCGACTGCACAGCGGCGAAAAGCCCTTCCAGTGCTCCAAGTGCCTCAAGCGCTTCTCTCACTCCGGCTCCTACAGCCAACACATGAATCATCGTTACTCTTACTGCAAGCCGTATAGAGAATAG
Protein Sequence: MSMTLVRNTFKGCSEDEAAGVVNAEVGGGCAAGAPTTGSGVGGGSGTGSEAGGGGGGGGGAGTGTGGGGGGVRGGGGSGGGEGGSTKQGGEKCPQCGFLCRDVHVLQLHLEDTHKTPYAIDKNDLNAQFPQVSCRVCSKTFANVYRLQRHMISHDESAVLRKFKCPHCEKAFKFKHHLKEHLRIHSGEKPFLCNNCGKRFSHSGSYSSHMTSKKCLIVNLKKSRHTNVSNVDRGPKKAQQPLPPGRREVDLLAANNNTFLPILPKLSPSDYQEIQREGAGIYDMPTLLPQMMGFGSYFLQASLGKILNQLHSKRLDEVAEKFESHRELMSPSTADSEGTEGTEGKESPAPTDPQGLDAVRRILETVNTSVTKQLLEANVRKLSTSPATMKREFEEDYQDQDSEMSSEMAHYPDWSAADQYDSQSEGLAAKLEDVNQPSAKSGYKRKAEDSSEADSEDEEDGTQTHNDNGRRVRARSLIDDEQLAVLKGYYAINPRPKKEEIIMIANYINFPTRVVQVWFQNSRARDRRESKIPPLVPLANPTSQTAYEQPLDLSKKEALTETACKDSETICAKFTSSSPVEPKNDNAPSHNQDADDLEDSPLVIDEETTDSVETKRTAPMGGEIVPKSQPQTNVKNESENTSQPEASPAAEIEQGVYFCDRCDKTFSKHSSLARHKYEHSGQRPYKCVECPRAFKHKHHLTEHKRLHSGEKPFQCSKCLKRFSHSGSYSQHMNHRYSYCKPYRE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00086058;
90% Identity: iTF_00982854;
80% Identity: iTF_00227167;