Basic Information

Gene Symbol
-
Assembly
GCA_014825855.1
Location
CM026142.1:3310919-3313785[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 13 0.38 37 5.2 0.5 2 19 105 122 104 125 0.90
2 13 0.0052 0.5 11.1 0.9 1 22 131 152 131 152 0.95
3 13 0.012 1.1 9.9 6.7 1 23 162 185 162 185 0.93
4 13 1.1e-05 0.0011 19.5 4.5 1 23 501 524 501 524 0.97
5 13 1.4 1.4e+02 3.4 0.3 5 23 531 550 530 550 0.94
6 13 0.00012 0.012 16.2 1.3 2 23 557 578 557 578 0.96
7 13 0.88 84 4.1 3.7 1 20 604 623 604 625 0.89
8 13 0.016 1.5 9.5 2.9 1 22 726 747 726 747 0.96
9 13 4.9e-05 0.0047 17.5 1.2 2 23 755 777 755 777 0.95
10 13 0.07 6.7 7.5 4.8 1 23 787 810 787 810 0.95
11 13 0.19 18 6.2 0.6 3 19 831 847 830 850 0.93
12 13 0.29 28 5.6 1.7 1 21 857 877 857 880 0.74
13 13 0.0076 0.73 10.5 5.8 1 23 891 914 891 914 0.94

Sequence Information

Coding Sequence
ATGATATTTATGGCACGATTGACTTCAATTACTAGACTAGGACTGTTTCATAGATTTTTCCCTTTTGAATATGAAATAAATATAAAGGATGAGCCAATCGATCCAGAGATCTGCAATGATTTGTCGCCAGTTGATACGAATACAGGGAATGAAAATGGAACAGCAACGTTTAAAAGTGAATATTTGGATGACGTTTATTGTAAGAATGAAGAATCCGCGTTTCCTCAAGAAAGTACGCATTTAGAAAATAACAAATTGGAAAATACTGATAAACGAAAAAGTAAACATAATATACCTCCAAACAACAGAATAAGCTGCAATGTTTGTTTCTTAACTTTTCAAACTAAACATTTATTGGGACTGCATAATAAATTATATAGCTGTAATGCATTTAAGTGTAATAATTGCTCTGCGATCTTCACTATGCATATTTCGTTGATCCGTCATTTAAAGAAGCAATGTTATACGAGAAAATTGTCTGGATATAGATGTAATTTTTGTAACCGGATGTTTTCCTATAAAAGACACATCCAATCTCATTTATTCCATGCGCATGGGAACGAAATATTTTCTAGTGAAAGCAAAATTACGAAAACATCTCCTGAATCGTTAGGAAAGTCGAATCATTCGAATGATATAGTCATGGCAGAATCAAATACTTCACACAGTCCCTCCCCAAAAAACGTAAATAGCTCAATAAATATATCTTTGGAACTATCTAATAGTTCAAACAATACACTCACCGAGGGTTCGAGCAGCAAGATCAAGTCTACGCATCCGAAATTGTTAAACGATTCGCATGGTACATCTTCGAAAAGGACGAAGCTGACTTCAACGCTCGAGACATTTGGTAACAAGACATCAACGGCTGCAGAAGTTATTCAGATGTCTACTTCTGTTAAGCGAATCGAATCTCCTGTTAGGAAAATCCCATTTGTTCAAATTTATGTGAATTTAAAAACAATGACATCTTCATTAAGGAACGAAATAAAAGCTGAATCTGAAAGCTCTAATACCTCGCACAATATGTCTTACAACCTTAGGCCAATGAAAAGATGTTCCTCTTCTTTATATGATCTTTACGATAACGAGACCTTTGAAAGATCAAGAAAATCTTTTAAAAGAAACAATTCTCCCTATATATTTAATCAAAGTAGAAAATCTGTACCTGAAACTAAGCGTAAAGAATGTGTGGTCTGTTTGGAGAAATACGACAAATTCTCCGAGCCTACTAGTTTTGTGTCAAACGAAGACGAAGATGAAAACGAAAAGGAAAACGAAAACGAAGACGCTTTCAAACAAGCAGTATCGAACAATGTGAAAGAGAAATTTGAAGGTTTTCGTGAAACAAGCTCGGCATGTAACTTGCCTTCGAAAGCTGATACGATTGCGTCAAAGCGATTCAATGAATTTGTAAAATCTTCCACTGATAGATTAATCGTACCTCAACAAGAATCGGTCGAATTTCAGAAGAACTTTAAGGTTAATCAGAAGAAAATATTTCAATGTTGTATTTGTAAAAAATCGTTTTCTTTGAAGGAGAACCTGCGCGAGCACATGAAATTGTTCCATACGATTTACATATCGAGCATATGCAACGCGCGTTACACGTCCATGAATAAGTTACTAACTCACTATCTACGTCAGCATATTGTGTTTAAACGAAGGGAATGTTGCGTGTGTAATGAGAAGTTTGACACGTCGGCATTGTTGAAACGGCACATGATTTTGCATTGTTTAAAGACCATAGGATCAGAAAAGAAAGCTCCGGTTGACGTTGAAATAAATTGCAATGCATTCAAGAAACAACACAAATGCAAAGGTTGTCGCAAACGATTTTGGCTATACTCATGTTTGAAACAACATGAGAACGTATGTCGTCGAATGAAAGTCTTAATAAATAAACAACGTGTACCTTGTGTAAACCATTTGTCTCGGTCCTTGGAAGAATCAAGTGACATGGAACTCGGCATAATACAATCACCTGATTTGGAACAAACGTTGGATGTTTCGGATGAGACGACAAGATCTGTGGAAAATTATTTGGCTCCGAGTACGTCTATTACGGATAATACTTCCTCTTCGTCATTCGATACAGCTGCAGAGAACAAAAGGTTACTTAATGAGATTGCATGTGTAAAGGGTTACCAAGCGGACAAGATGAACAGAACAAAGTTTCCTTGCACTACTTGTGGAACACAATTCCAAACATTTAAAAATTTCTGCATACACGAGCGCACCTATTGCCAAACAGCCACAGAAAAGTGTAACGTTTGTAACACGATGTTTTCCACTAAAAGATTATTACAGTATCACATGCTTGCTACTCATATGCCTTCGTGCTCGGTGAACTACAAATTCTTTTGTAAGTTCTGTAATCAAGGATTTCTTAAGAAATCGAATCTTCAAATTCACGAACGACACTTTCATATCAGGCAGGATTCTAGACTGGTGCTAAATTCCGATTGCGTTTTGAAAGATAAACCAATCTGTAATATATGCCATTTGTTATTCGAATCCTACGAACATTTATTTGAGCATAACATGTATTATTACAAGGGCAATGTTTTTTTATGTACAATGTGTGGTAAGTCGTTTCAAGGAATGTACAAGTTTGATTATCACAACAAGTTGAAGCATTATGTGGACGAACCATCGAAATTATACCCTTACAAATGCGATACTTGTAACGAAGGCTTCAGCTACGAATCACATTTCCACGCACATAAGCTGCACGTTCATTTGCACGATTCGCCCGCTAACGAGACGCGCGATCGCGATACATCGAATCAGACTTTTCGCATGTATTCACGATTCTTTGAATAA
Protein Sequence
MIFMARLTSITRLGLFHRFFPFEYEINIKDEPIDPEICNDLSPVDTNTGNENGTATFKSEYLDDVYCKNEESAFPQESTHLENNKLENTDKRKSKHNIPPNNRISCNVCFLTFQTKHLLGLHNKLYSCNAFKCNNCSAIFTMHISLIRHLKKQCYTRKLSGYRCNFCNRMFSYKRHIQSHLFHAHGNEIFSSESKITKTSPESLGKSNHSNDIVMAESNTSHSPSPKNVNSSINISLELSNSSNNTLTEGSSSKIKSTHPKLLNDSHGTSSKRTKLTSTLETFGNKTSTAAEVIQMSTSVKRIESPVRKIPFVQIYVNLKTMTSSLRNEIKAESESSNTSHNMSYNLRPMKRCSSSLYDLYDNETFERSRKSFKRNNSPYIFNQSRKSVPETKRKECVVCLEKYDKFSEPTSFVSNEDEDENEKENENEDAFKQAVSNNVKEKFEGFRETSSACNLPSKADTIASKRFNEFVKSSTDRLIVPQQESVEFQKNFKVNQKKIFQCCICKKSFSLKENLREHMKLFHTIYISSICNARYTSMNKLLTHYLRQHIVFKRRECCVCNEKFDTSALLKRHMILHCLKTIGSEKKAPVDVEINCNAFKKQHKCKGCRKRFWLYSCLKQHENVCRRMKVLINKQRVPCVNHLSRSLEESSDMELGIIQSPDLEQTLDVSDETTRSVENYLAPSTSITDNTSSSSFDTAAENKRLLNEIACVKGYQADKMNRTKFPCTTCGTQFQTFKNFCIHERTYCQTATEKCNVCNTMFSTKRLLQYHMLATHMPSCSVNYKFFCKFCNQGFLKKSNLQIHERHFHIRQDSRLVLNSDCVLKDKPICNICHLLFESYEHLFEHNMYYYKGNVFLCTMCGKSFQGMYKFDYHNKLKHYVDEPSKLYPYKCDTCNEGFSYESHFHAHKLHVHLHDSPANETRDRDTSNQTFRMYSRFFE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00222771; iTF_00222768;
90% Identity
-
80% Identity
-