Basic Information

Gene Symbol
-
Assembly
GCA_014737485.1
Location
JACXIP010000021.1:3262276-3266998[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 9 0.35 35 5.3 1.6 1 23 597 620 597 620 0.98
2 9 8.8e-05 0.0089 16.6 0.3 1 23 626 648 626 648 0.97
3 9 0.9 90 4.0 0.8 1 23 654 676 654 676 0.86
4 9 3.7e-06 0.00037 21.0 0.4 2 23 683 704 682 704 0.96
5 9 0.09 9.1 7.2 0.3 2 23 711 733 710 733 0.95
6 9 4.1e-05 0.0041 17.7 3.7 1 23 737 759 737 759 0.98
7 9 0.013 1.3 9.8 0.7 1 23 764 786 764 786 0.98
8 9 1.4e-07 1.4e-05 25.5 0.5 1 23 792 814 792 814 0.98
9 9 3.3e-05 0.0033 18.0 0.7 1 21 819 839 819 840 0.94

Sequence Information

Coding Sequence
ATGATAAAGAAGAACGATGGGCTGCCGCAGATTGTTTGTTTGCGATGTTTGGGTATCCTGGAATTCTTCTGCGACTTTTATGATCGCTGTCATCTGGTACAACAGCAGTTCTTGCAGGCTAGTCAAAATACAACAGATGAGAAGTTCCAGCAAGATAGCGATGCTGAATCTGATAAGGAGAACGCTATTCCATCTGCGAATGAGATGAAACGGAAAGCTAAGGCATTATCACCTGAAAGTTTAAAGAGTACAAAAAATTATCTGTCCGAAAATAATACGTCGTACCGCAGGGCTGAAAGAAAAGAAGAAAACGTCAATCTCGTAAATAATTCCCCTATTAATGATGTTCACTCGGTTACACAAACTACGGTACATATAAGCAATGTAATTTCATGTGAAAAAATATCGGGGAGCGACCAGCGTGATGCTAGTAATTTAGAAGAGAATACAAACAATTTAAAACATAAAAAATTAAATGACAATATATCAAGAAAGACTGCAGTTCGTACAAGATCAATGAATAACTTGAACTCGCCGCAAAAAGATGAGGAGGACATTAGTATAAATAATACACATCAGCCTGTAGGACGTAGAAAAGGACGGAAAAACAAATTGGAGAAGATGAGAGGAGCCAGTTTCTCAGCAGGCAGCAGAAAAAAGAAAAAGACGGAAGAAGAACAAGAAAAGATAATCCAAAATGATATGGGTAAGAGTGATACTTTAAATAGTAGTTTAAAAAATTTGGATAACAAATGCAAAAGCAGCTGCCTGCATGTTATTTATGATAATGATAAGTCCAATAGTGTGATTAATAATATTGAAAACTCCCCCAAACCACAAGTTGAGCAAGAGGCAATGAAGGAACAGGTGGCAGTGGTGGACACATCCTCAAATATAATTTATACCAAAGTTAAGGAACCTGATATTGTATACATAAATAATGAAAATCATCATATTGGTGATGATTTAGTAATTAATAAATTAAGAGAAATGAAATCTGATGGTAAAAGCACAGAAAAACCTGGCAGCTGTTTGAACAATACAGGAGATAGGTCTGTAAAAAGTAAAGCAATATCAGTTATTGTAAAGCAAGAGAAAGGAGAAGCAGGAAGTACTCCACCTAGCAAGACTGAAAAGACAAATCAGCTTGTTCTGATTCCTAATAAGATACTAATACAGAAAGATAAAAGTAGTGTAGTGAAGAATCATGATCAAAAAGGAAAAAAGTTAGATTTAACGCAGACATCTTGTACATTGGTGGAGGAATCTGAGAAAACTGAAAATAGTGAGACTAATTTAGTAACAGTACAAAATATTATTAAGCATTCTGATGTTTCTTATAATCCGCAATCAAAAATATTTACAGAACAAAATCGTGTGACCGTTATAAGGTCTTCGCAATCTAATGAATTATCAAATCCAAAGATGATGCAGGAAGATTCCACAGAACCGTGCATTGCAATAGATGTAATAGACCAAAGTACTACAAATGAGATAGAATGCAACCTCAGCAAACATTCATTATCTCGACTCAGTGAAGATAGTTTTAATAAAATTAAAAGTAAAGATAGATCGTTTGGAAAAATCTCCGAATTGATAAGTGATGAACAAAAACGAGCTATTGAGACTTATTACACGGTGGACATGTCGATAGTAAATTCAGAAGAAGTACAGAAAAACATAACGATAATTAATAAAAAGAATATACGCTGCAATATTTGTGGCTCCATTTATCTCAGGATGGATAAGTGTCATGTACATATTTGGGGACATTTACAAATGAAGCCCTATCAATGCAAAGCTTGTGACTTTGCCACAGTTACTGTTAGCAATGTTCGATGCCATATCAGAAAAAGTCATTTAAAAATTAAACCATTCGCGTGCCATCTATGTGAAAAACGATATGTAAATGCCATTTTATTAGAAGAGCATATTAATACTCATACAGGTGCCCGTCCATACAAGTGCAAGCTCTGTGATTTTGCAAGTTCCAGTAGACAAATATTAAGTTATCATAATGCCACTCATAAACCATTGAAGGATATTAGCTGTAAACTTTGTGGAAAAGAGTTTTATTCAAAAAGCAGACTGCGTGCACACATGATCGTACACAACAAAGATAAAGCTGTTATGTGTAAACTATGTTCTGCTTATTTATCTAATGCAGAAGCATTAGAAACGCATCATAGAAACATTCACATGCAAGATTATGTATGTAACATATGCGGTAAACACACCAAGTCAAGAAAAGCTTTACATAATCATCAAAATGTTCACGCTGCTGCAAAATACAAATGTACTCTATGCCCAAATGTGTATAAGAGTAGTCAAATACTAAAAGAACATCTTTTAAAACATGAAGGTATTAGAAAGTACAAATGTAATGTCTGTGAAAAGTCGTTTGGTCAGCAGTCTCATTTAGCTGCTCACATGGCAGTACATAGCAAAATTAGATTTCATTGTCCTGGATGTGACAAACCTTTCAATCGTCTGGACAATATGAAGATACATACTAAACGATGTAAACCATTTTTGGCAAATCCAGAGCTAAAAAATCTTTTAAGTAGGAGAGAAAGGACTATATCGTTCAATAATATAGCAGAATTAACTGCAGAACTAAAGACTGGTAATATGACAAATTCTATGTCTCAAGTTTCTTTAGAAAAGCAGAATGATGAAATGTTAGTAGTAAAGACTGTGGAGCATGAACAAAAGACTGCATTGAATCTTCGCAAATTAGGGCTAAATATTTCTTGCATTGAACCAACAGAAAAAACATGGAATTCTGATAAGATGTATAATGAAAAAGAAGTAATGAAATCTTCTGAAAACATTGCAATTAACGTTACAAATATCGATGACAGATTAGTTCCAGAAAATGAAAATGTGTCAATTCTTGAAAACGTCTTAGGACCAGAAAATTATTAA
Protein Sequence
MIKKNDGLPQIVCLRCLGILEFFCDFYDRCHLVQQQFLQASQNTTDEKFQQDSDAESDKENAIPSANEMKRKAKALSPESLKSTKNYLSENNTSYRRAERKEENVNLVNNSPINDVHSVTQTTVHISNVISCEKISGSDQRDASNLEENTNNLKHKKLNDNISRKTAVRTRSMNNLNSPQKDEEDISINNTHQPVGRRKGRKNKLEKMRGASFSAGSRKKKKTEEEQEKIIQNDMGKSDTLNSSLKNLDNKCKSSCLHVIYDNDKSNSVINNIENSPKPQVEQEAMKEQVAVVDTSSNIIYTKVKEPDIVYINNENHHIGDDLVINKLREMKSDGKSTEKPGSCLNNTGDRSVKSKAISVIVKQEKGEAGSTPPSKTEKTNQLVLIPNKILIQKDKSSVVKNHDQKGKKLDLTQTSCTLVEESEKTENSETNLVTVQNIIKHSDVSYNPQSKIFTEQNRVTVIRSSQSNELSNPKMMQEDSTEPCIAIDVIDQSTTNEIECNLSKHSLSRLSEDSFNKIKSKDRSFGKISELISDEQKRAIETYYTVDMSIVNSEEVQKNITIINKKNIRCNICGSIYLRMDKCHVHIWGHLQMKPYQCKACDFATVTVSNVRCHIRKSHLKIKPFACHLCEKRYVNAILLEEHINTHTGARPYKCKLCDFASSSRQILSYHNATHKPLKDISCKLCGKEFYSKSRLRAHMIVHNKDKAVMCKLCSAYLSNAEALETHHRNIHMQDYVCNICGKHTKSRKALHNHQNVHAAAKYKCTLCPNVYKSSQILKEHLLKHEGIRKYKCNVCEKSFGQQSHLAAHMAVHSKIRFHCPGCDKPFNRLDNMKIHTKRCKPFLANPELKNLLSRRERTISFNNIAELTAELKTGNMTNSMSQVSLEKQNDEMLVVKTVEHEQKTALNLRKLGLNISCIEPTEKTWNSDKMYNEKEVMKSSENIAINVTNIDDRLVPENENVSILENVLGPENY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00220808;
90% Identity
iTF_00227489;
80% Identity
-