Basic Information

Gene Symbol
-
Assembly
GCA_034509555.1
Location
CM067411.1:3133637-3135110[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 9 0.0012 0.097 13.3 3.4 2 23 79 100 78 100 0.97
2 9 1.7e-05 0.0013 19.2 1.9 1 23 102 125 102 125 0.96
3 9 0.0011 0.089 13.4 0.9 1 23 130 153 130 153 0.96
4 9 0.00013 0.01 16.4 2.2 1 23 159 182 159 182 0.95
5 9 0.00048 0.038 14.6 2.0 2 23 189 211 188 211 0.95
6 9 0.0031 0.25 12.0 0.3 1 23 216 238 216 238 0.96
7 9 0.00028 0.022 15.3 0.5 3 23 246 265 245 265 0.98
8 9 2.5e-06 0.0002 21.8 0.1 1 23 271 293 271 293 0.97
9 9 0.00022 0.017 15.7 0.4 1 23 299 321 299 321 0.97

Sequence Information

Coding Sequence
ATGGCTACGACTGTTCTGGATCGCATTAGAAGAGCGAGAAGaATCTTGGATCCTTTGAGCGAAGAATTCAAGACCGACTCGCAGGCTCACTTACAGTTAGAGCTCCCCGAGGTATACGAGAATTGGATCGACAAAGAAAACTTCGAGATCATGTCCGCTAGCCAAGAGGAAGCCGCGGTATCTCCTCAAAACAATCCCAGCCAACGATCCAAAAAGAAAACCTTGACTCGTCTAGAATGCGATCACTGTCGACGAAAATTCTTGAAGAAGAGCAACTTGGCGGAGCATTTGAAGAAACACAGACACAAGTGTTCAGACTGTCCGAAGACCTTCAGACTTCGTCGATACCTAGCTTCTCACATAGAGAAGATCCATCGACGTCAAGTGTACGATTGCAGTGTTTGCGAATACAAAAGCAATAACAAGGGAACACTGAAGAATCACTACATTCGTCTGCACACGACTAATTACAATTTCGCTTGCGACACTTGTGGCAAACAATTCAAGATAAAGAAAGCACTGAACCATCACGTGAAACAGAATCATAGCGACGCGCCACCGATAGTGTGCGACGTTTGCGGCCACTTCAGCAAGAATCTTCATGCTCTCAAGGCTCATATGAAGTACAGACACTATAAGCCTGAGTTTATCTGCAGAATCTGCAGAAGAGGGATGACGACTCAAGAGAATTTGGAGCAACACTTAACCTGGCACGAGACCAGGGAAAAGGTGCTGTGCCCCACGTGTGGAAAGAGATTTCGAGGTCGGGATTTGGACTCTCATATGCGAGTGCATACAGGAGTCAAGCCTTTTCCTTGTCCTGTTTGTGGAAAGACATTCAGAAGGCAGACTGCCCAAGAGCAGCATGTTCTCATTCATACGGGAAAGAGACCGTATGTTTGCGATATCTGTGGGCAAGCGTTTGCTCAGAAACCTGGGCTGATTTGCCATAGGAAGCGCCATCCTGGACCTCTGCCTCCATTACCTGTCGTATCCATCAAGAATATCGTCACGGAGTTCACTAAGGAGTACACTATGAAGaatacgattattaaaatcgaataa
Protein Sequence
MATTVLDRIRRARRILDPLSEEFKTDSQAHLQLELPEVYENWIDKENFEIMSASQEEAAVSPQNNPSQRSKKKTLTRLECDHCRRKFLKKSNLAEHLKKHRHKCSDCPKTFRLRRYLASHIEKIHRRQVYDCSVCEYKSNNKGTLKNHYIRLHTTNYNFACDTCGKQFKIKKALNHHVKQNHSDAPPIVCDVCGHFSKNLHALKAHMKYRHYKPEFICRICRRGMTTQENLEQHLTWHETREKVLCPTCGKRFRGRDLDSHMRVHTGVKPFPCPVCGKTFRRQTAQEQHVLIHTGKRPYVCDICGQAFAQKPGLICHRKRHPGPLPPLPVVSIKNIVTEFTKEYTMKNTIIKIE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00360409;
90% Identity
iTF_00015577;
80% Identity
-