Blap009536.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Bombus lapidarius
Gene Symbol
-
Assembly
GCA_936014575.1
Location
CAKXZU010000033.1:730868-734026[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 6 0.031 2.2 8.8 0.0 2 23 122 144 122 144 0.92
2 6 0.00026 0.018 15.4 1.6 1 23 154 177 154 177 0.94
3 6 0.00012 0.0083 16.4 2.7 1 23 187 209 187 209 0.97
4 6 1.4e-06 9.5e-05 22.5 2.1 1 23 345 367 345 367 0.97
5 6 1.7e-06 0.00012 22.2 0.2 1 23 373 395 373 395 0.98
6 6 1.6e-06 0.00011 22.3 4.1 1 23 401 423 401 423 0.98

Sequence Information

Coding Sequence
ATGGGAAGCAGCCAGAGGATAGAGATAAATAAAGGGAACACGAAAGAAGAAGAAATGGAAAAGAAAAATAGAAATGGTGCTCCGAAAGCTTATGCGTCTTTCTGGCGTTCGTTGTACTCGCGATTCCCGCCGTTCTATCGTCTCCGGATGTTAAAAGAAAAACATCTCACATCCACATCGCTATATACACGAATCAACCGTAACGGAATTCCATCTAACAGACCACGATCATTTCAGGTGTCGCTGGCCCTCGGTTTGGATGCAGGAGGTTGGGGTGCCCTGGTGGAACGCACGAGTGGCGGCGGCGGAAGCGGTTCCCTGCTAGGTCACGGCGGTTTCGCCGGTCTGGCGGGGTTGGCGCGTCGCTGCGGCGTCTGTCTGGCTACGTTTCCTTCCGCCTGGTTGCTGGAACGGCACGCGTTGCTTCAGCACGCCGGCCAGGCTAGCGACGACAAACCATTCACCTGCGAGCAATGCGGCCAACGCTACCGTTACCGATCCGCTTACGTGAAACACCGGGAGCAAAACCATCGGGCCCGCCTACcggccgataagcttttcacctgcgacgtctgcggcatgcagttcaggtacctaaagtccttcaagaagcacCGACTGAACCATGCGTTGGAACGATTGCAACGAGCTCCGGAGCCTCAGAGCAGCGCGATGACGGTGTCCGCGGCTGCAGAGAGGAGCGACCAGGTGTCCAGCACCGGGGAACCATCGCAGGTGGAGACAGGCAGCGACACCACTACCAATCCAGGTGAGGAAGAGACGCGGGGAACCTTCAATGAAAATGCTCGCGAAGAGAGCATCTCTGAGACAGCCAGCGTGCAGGAGAACCCTGGCGAGGCTGTCGAGGTTCAGATGACAGAGGCTCCTACAGGAAACAGCAGATCAGCCGGTGGTACCAGCGAGGTCGGCGACACGGATGACAACGCTGTGGACGACGATCGTTCCGAACACACGGATCCTGTGATCAGCCTGGctcgcagcagtcacgaggttgacaggcgtgaacgtcgcttcgcctgccccttttgcggtaagtgcgtccgttcgaaggagaacctgaaactccacgtacgtaagcacaccggcgaacgaccgttcgtctgtctcttctgcggacgcgcgttcggcggaaaaagcgaccttactaggcatcttcgtatccataccggagagaggccgtatcactgcgaaatgtgcggcaaatgtttcgccagggcggattatttgtccaagcatctcaccacccatatacaccaacgcTAA
Protein Sequence
MGSSQRIEINKGNTKEEEMEKKNRNGAPKAYASFWRSLYSRFPPFYRLRMLKEKHLTSTSLYTRINRNGIPSNRPRSFQVSLALGLDAGGWGALVERTSGGGGSGSLLGHGGFAGLAGLARRCGVCLATFPSAWLLERHALLQHAGQASDDKPFTCEQCGQRYRYRSAYVKHREQNHRARLPADKLFTCDVCGMQFRYLKSFKKHRLNHALERLQRAPEPQSSAMTVSAAAERSDQVSSTGEPSQVETGSDTTTNPGEEETRGTFNENAREESISETASVQENPGEAVEVQMTEAPTGNSRSAGGTSEVGDTDDNAVDDDRSEHTDPVISLARSSHEVDRRERRFACPFCGKCVRSKENLKLHVRKHTGERPFVCLFCGRAFGGKSDLTRHLRIHTGERPYHCEMCGKCFARADYLSKHLTTHIHQR