Basic Information

Insect: Bombus impatiens
Gene Symbol: mecom-b
Assembly: GCA_000188095.4
Location: NT:4982-33422[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.0012 0.077 12.7 0.3 2 23 317 339 316 339 0.96

2 9 0.12 7.2 6.5 0.1 1 23 346 369 346 369 0.93

3 9 1.1e-05 0.00069 19.1 1.5 1 23 375 402 375 403 0.93

4 9 3.6e-06 0.00022 20.7 2.6 1 23 409 431 409 431 0.95

5 9 2.2e-05 0.0014 18.2 5.0 1 23 437 459 437 459 0.99

6 9 0.00044 0.027 14.1 0.7 2 21 467 486 466 487 0.95

7 9 5.2e-09 3.2e-07 29.6 1.2 1 23 842 864 842 864 0.99

8 9 2.7e-07 1.7e-05 24.2 1.7 1 23 870 893 870 893 0.97

9 9 7.6e-06 0.00048 19.6 3.4 1 23 899 921 899 921 0.99

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.0012	0.077	12.7	0.3	2	23	317	339	316	339	0.96
2	9	0.12	7.2	6.5	0.1	1	23	346	369	346	369	0.93
3	9	1.1e-05	0.00069	19.1	1.5	1	23	375	402	375	403	0.93
4	9	3.6e-06	0.00022	20.7	2.6	1	23	409	431	409	431	0.95
5	9	2.2e-05	0.0014	18.2	5.0	1	23	437	459	437	459	0.99
6	9	0.00044	0.027	14.1	0.7	2	21	467	486	466	487	0.95
7	9	5.2e-09	3.2e-07	29.6	1.2	1	23	842	864	842	864	0.99
8	9	2.7e-07	1.7e-05	24.2	1.7	1	23	870	893	870	893	0.97
9	9	7.6e-06	0.00048	19.6	3.4	1	23	899	921	899	921	0.99

Sequence Information

Coding Sequence: ATGAACGGTCTCGATTTGTCTCGACCCACGGTCGACTCCAAGATGAACGGAAGCAGTGACGAAGGCGAGTCGATGTCAGGCACGCCGGCCGGTGGAGGTACGGGGGGAACCGGCGAAAATCAAGAAATGGAGGAAAACGGTTCGATTCGTGGCGGCAGCAACTCTGCCAATAATCTAGTATACAGAGATCTGAAGGCTCTTCACGCGACCAGTGTCCACGACGTGTCTCAGGATTATAATCCGCAATCGAGGCCGGCTTATCAATGTGGCTATTCGCCCGCCATGGACAAACAACATCAGAATTACGAAAAGGAACAGCACAGACCACCTTCATCCAGAGACGAGGAGAAATCTTCGTGGGAATACGGCGAGAAGGCTGACAGGAAGGAGTATTTGAGATCACGAGACGCCGTCTACAGGAACGAAGCGTATCAGGACGCGACCAAACAGGAACAAAAGGAGCAATCTAACCGCGAGTGGGTATCACCGGTACCGGAAGTGGAGGTGGGAGGTTCGGCACCGGGTGGCCCTCAGGTTCGAGCGCGGAAGGACATTCCACGGGGTGCGAGATTCGGACCTTTTCTTGGAAAATGGGCGAGCGAGCCTTTCAACCCCCGTTACGCGTGGGAGGTTCGTACAGCTGGAAGTGGAGTCAGGGGATGGTTGGACGCATCCCACGAAACAAATAATTGGTTGAAGTATGTCCGAAGCACTAGCAGTCCGCACACCGTTAATATGCGACACGTGCTTATTGGTGGACAGATGGTGTACGAAGCGGTGCGGGATATAGCGGCGGGTGAAGAGCTGCTTCTCGGTGTTCGAGAACCTCTTCAACTTCAGGATATGCTTGGTGAAAATACTACCGAGGACAGAAGCGATCGAGAGACCGCCTCGCAACACAGTGGGACCGTAGACGAAGATAAAGAAGACGAGGAGGAAGGGGAGACCAGATGCCCTGTCTGCGACAAACCGTTTCAAGATATTGAGCTATTGGACAGTCACCTGATAACGTGTCACAGATATCCAGCGGAACAGCATCGCTGCGACAATTGTCCCCGTGCGTACGCCTGGCGACCACTGTTGGTTCGTCATCGTGCGATCGTTCACGGTGATCTCCGCAACTACCCCTGCGAGAACTGTCCGAAGTCGGACAAACCGCAGGTCTTCACGGACCCGTCGAACCTCCAACGTCACATCAGGACTCACCACGTGGGCGCGAGAAGCCACGCGTGCACCGAATGCGGAAAGACGTTCGCCACCAGTTCCGGTCTCAAGCAGCACACTCATATCCACAGCAGCGTGAAACCGTTTCAGTGCGAGGTCTGCTTCAAGGCATACACGCAGTTCTCGAACCTATGCCGACACAAACGAATGCATGCTGATTGTCGTATGCAGATCAAATGCGTTAAATGCGGACAGTCCTTCAGCACGGTCACCTCGTTATCAAAGCATAAGCGATTCTGCGATTCGACACCGCCGACCGGTCCACCTGGCGCCATGCCGCAGTTACCAACCCCAGCGCCGAGTCCTTTTCTGGTCTATCCCAGACCTCCGGTCAGTCTCCCAGGAGGTTTGCCTTTCTACCCACCAAGTTTGATGGGACCCTATCCAGGAATTTTCCCGAACGCTCCTAACTTTTTGAACACTCCGCTCTTGTTCCCGCCAAAAGTTGAGGAAGCTGAGAAAAGGAGCGACAGTCCAAAGAAAGAGCGCTTCACCCCGCCGAGAGTACTGCCGCAGCATAGTAAAGTATCTCCATCCACTGCTGAGGAGGCTACCTCCTCGTTCAGACCATCTCCAGCTAGGCCACCTGTCCAGCCAACTCCCGAGAGCGACGACGATCCCTCTAAGAAACGGGAGACCAATAGaaacaacgagaaaaagaCGGATTCTGAACATGCCCCGGCGACCACGAACGAAGAGACGACGGATCAACCTTTAGATCTGAGAGTCCAAACGAAGAAGCAACGAACGAATTCGAACACcgcagagagaaagagtcGTAGCCCGTCACCAACGCCAGCGCCGATGGAAGAAGCACCACCTCCTCCAGATCCTCCAAAACCCGAGGAAGAGACGCCCGTGCCAATGGAGGTCGATTCCAAGGATGTGCCCAGCAGCCCGCAGCTGAGAACCAGCCTACCCACGGAACAACCACCTACCACCACACCACCGCACATGGCGTATCCCAGACCGATTCACCCGATGTTGCTGGAGGCCATGTATCGCGGACCAACTAGTTCCTTCCCAGGATTTCCAGGTGGACCACCGCCTCCTGGTAGTGCAACCCCGGAATCCAGACTGCTACCACCGCTACCGCCCTTCGGACCACCGCGTGGGCTTCCTTTTTTAGGGACATTTATGAACGGGCTCAGCGGCGCTAGGCCAGGAGGCGGAGGATTCGACCTGCTTGCCAGGCCGCCGTTGGGACCGTTCCCCGGCGTGAAGCCGTTCCAAGAGGCCGTGATCGCGCCccatcaccatcatcatcatcatcacgCCCACGGCAAAATGAAAGACCGATATTCCTGCAAGTTCTGCGGAAAGGTGTTCCCCCGATCCGCTAATTTGACCAGACATTTGCGTACACATACCGGTGAACAACCTTACAAATGCAAGTATTGCGAGCGGTCCTTCAGCATCTCCAGTAATCTTCAGCGGCACGTGAGGAATATCCACGACAAACAGAGACCTTTCAAGTGTCCGCTTTGCGAGAGATGCTTTGGCCAACAGACAAATTTAGACAGACATCTGAAGAAACACGAAGCCGACGACGGTAGTGGCGTTGTTTCCGTGGCGGATTCACCGGGAAGCAGCAACGAAAACGAACGAGAGGACACGTACTTCGACGAAATCAGATCGTTCATGGGAAAAGTGACTTATGGTGGCGAGGCTGGCTATGGATTGCCCCCACACCCGGCCTATTTACCTAGTCGACTTCACGAGATGCACGAGTCCAAGATGGAAACGGAATACGACGAAGACGAGGATAGCGAGGAAGGAGTCTCTCCTTTGGATGAAACGGATGGCTTGTCACCCGCAGAGGCTAAAGAATCCACTCCACCACCGCAATACGATCTGAAGCTGAGGGAGAAGCAGGAACTGCTCAACAATAACACGGCCGAGCCTGTCATTGAGATTTCCACATAG
Protein Sequence: MNGLDLSRPTVDSKMNGSSDEGESMSGTPAGGGTGGTGENQEMEENGSIRGGSNSANNLVYRDLKALHATSVHDVSQDYNPQSRPAYQCGYSPAMDKQHQNYEKEQHRPPSSRDEEKSSWEYGEKADRKEYLRSRDAVYRNEAYQDATKQEQKEQSNREWVSPVPEVEVGGSAPGGPQVRARKDIPRGARFGPFLGKWASEPFNPRYAWEVRTAGSGVRGWLDASHETNNWLKYVRSTSSPHTVNMRHVLIGGQMVYEAVRDIAAGEELLLGVREPLQLQDMLGENTTEDRSDRETASQHSGTVDEDKEDEEEGETRCPVCDKPFQDIELLDSHLITCHRYPAEQHRCDNCPRAYAWRPLLVRHRAIVHGDLRNYPCENCPKSDKPQVFTDPSNLQRHIRTHHVGARSHACTECGKTFATSSGLKQHTHIHSSVKPFQCEVCFKAYTQFSNLCRHKRMHADCRMQIKCVKCGQSFSTVTSLSKHKRFCDSTPPTGPPGAMPQLPTPAPSPFLVYPRPPVSLPGGLPFYPPSLMGPYPGIFPNAPNFLNTPLLFPPKVEEAEKRSDSPKKERFTPPRVLPQHSKVSPSTAEEATSSFRPSPARPPVQPTPESDDDPSKKRETNRNNEKKTDSEHAPATTNEETTDQPLDLRVQTKKQRTNSNTAERKSRSPSPTPAPMEEAPPPPDPPKPEEETPVPMEVDSKDVPSSPQLRTSLPTEQPPTTTPPHMAYPRPIHPMLLEAMYRGPTSSFPGFPGGPPPPGSATPESRLLPPLPPFGPPRGLPFLGTFMNGLSGARPGGGGFDLLARPPLGPFPGVKPFQEAVIAPHHHHHHHHAHGKMKDRYSCKFCGKVFPRSANLTRHLRTHTGEQPYKCKYCERSFSISSNLQRHVRNIHDKQRPFKCPLCERCFGQQTNLDRHLKKHEADDGSGVVSVADSPGSSNENEREDTYFDEIRSFMGKVTYGGEAGYGLPPHPAYLPSRLHEMHESKMETEYDEDEDSEEGVSPLDETDGLSPAEAKESTPPPQYDLKLREKQELLNNNTAEPVIEIST

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01539779;
90% Identity: iTF_00118172;
80% Identity: -