Bhor012286.1
Basic Information
- Insect
- Bombus hortorum
- Gene Symbol
- -
- Assembly
- GCA_905332935.1
- Location
- HG995192.1:3267525-3271570[-]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 13 2.4e-05 0.0026 18.4 1.7 1 23 91 113 91 113 0.98 2 13 7.2e-07 7.7e-05 23.2 0.6 1 23 119 141 119 141 0.98 3 13 0.00035 0.037 14.7 1.7 1 23 146 169 146 169 0.97 4 13 3.3e-05 0.0036 18.0 0.5 1 23 175 197 175 197 0.97 5 13 5.4e-05 0.0058 17.3 0.2 1 23 203 226 203 226 0.97 6 13 1e-06 0.00011 22.7 0.4 1 23 236 258 236 258 0.94 7 13 4.4e-05 0.0047 17.6 1.8 1 23 262 284 262 284 0.95 8 13 1.5e-05 0.0016 19.0 0.1 1 23 290 312 290 312 0.98 9 13 0.017 1.8 9.5 0.2 5 20 530 545 529 547 0.91 10 13 6.5 7e+02 1.3 0.4 15 23 567 575 559 575 0.87 11 13 0.11 12 6.9 0.1 1 17 581 597 581 598 0.92 12 13 4.2e-05 0.0045 17.6 1.8 1 23 668 691 668 691 0.96 13 13 1.9 2e+02 3.0 0.1 6 21 705 720 703 721 0.91
Sequence Information
- Coding Sequence
- ATGTTGAAAAATCACGTTGTTGATTGCAGAACTCTCGGGGTCGTACAGTGGGACGCGAAATCCAAAGACTGCGGTGACCAGGCCATCAAGATCTTCGAATCAAGATCACCCATATCGTCAGAATCATCGCCAGAGCAAGTGAATCCTTCGTCTGATAGAAAAGATCGTACATCGAGGGAGCTAAATTACCTTACAAATTCTGACAACGATTCACTGACAAATTCGTCTACAAAGAGGAGGAAGAATAAAAGATTCGAAGATCAAGAACAATACATCTGCTCCACCTGCAAGTTACGTTTTGACAGACAAGGAGACTACAAGCGTCACATGATCAAGCACAGCGATCTTCGTCCTTACAAATGCGAAATCTGCGACAAGGCGTTTAAACGTTCCTCGGAGGTGTCCAACCACACTCAGATCCACCGTGGTATCGAATACGCGTGCGAAGTATGCGGTTTCACCACGATAAATAAATTCTCTTTAAGAATGCATCATCGTCGAGTTCACCAGCGTGACTTTCGTTATCGTTGCGATCAATGTGACAAGGGTTTCATGTCTAATTACGATCTGGAGGACCACAAGGCCAGTCATCTAGGCAGGAAGACCTTCATCTGCGAATTCTGTGGCAACGCCTACTCCCAAAAATCCTACTTGGTAGCACACAAACGGGTAATCCATAGGATTCAAAAAAGCGCGCCGAAGGAGTACCAGTGCAATATCTGCAACAAGAGTTTCGCCACCGAGCAGAATCTTCGTAATCACGTTGGTCTACACTCGCAGATGTTCCTGTGCGCCCAGTGCGGCAAAAAATTCGCAACCAATCACGCTTTGAAGCTTCACGGTCGAAAACACACAGGGGAGAGACCTTACGAGTGTATGGTTTGCTCGAAAGCTTTCGCCAGATCGGCCGCGCTCAGAGTGCATAAATTAACACACACGGGCGAGAGGCCGAGGTGTACGATCGCAGAAACGTCCCTGGGCCAGGATAGAAATGATCGACTGCAGTTCCAAGATATTGTTCCAGCTTCCAATCCCACGATACAGAATTCCATGTGCCTCAATGTTGATATAGATTCCGACGAGAACAGTCAGATGACAGTCACAAACAACGAAGACGAAGTTAACGATAGTACTTCCACTTTAGGAAGAGAAATAGTTGATGATTCGATCGTGGAGCCGCTGAAATCTGTTTTGGTGCCTGTTAGAGTTCCAGTGACGAAGAAAATTAACCATATGTCGGTACCTTTTGAAACGAGGGACGAGTCTGGATTAAACACAATCAAAAGTATATTAATTCCTTTTCGAGCAGAGGATGGATCGGCGTCTCACGAAATTAAAAGGATCATTGTACCTATGAAGTCGGAATCGAGTTTATCGTCAGAAGAGGAAATTGCGAAAAAAACTTTATTAACAAATGAAGCTAGAAGTAAGCAGGTGAATTGTAAGGAAGAAAAGGAGAAAGAAAACGAAAAAAATCAGGAGACGTCATTGGGAAAAAGGACAAGGAGCCGAGAAAGGGAAAAGGAGGAACAAAAGAAAAAGAAGGTAGAAAATGAAATATTGGATACTTTAAAGAACATTTACCCATTCTGTCAGAAGTGTTTCAAAGACGAGGACGAAATGCAAAAACACGTCCTCCAGACACGTAAGAAACCATATAGTTGCGACAAGTATCATAAAAGCTACTTGTCCGACGTTACTCTAGAAGAACACCAGAGAACACACGATGTGGTTTTATTTTATCGGTGTTCCATCTGTCAGATACAGTACAAAACCGCGACAGGATTAAAGAATTATCAGACCCGTGAACACAGTGACATAGAGCCCAAATATACGTGTTATTGCTGTAAAAAGCAATTCAAATTAAAATTTGACCTAAACATTTACATCCACAAATTGCACATGAACACAAATTACATTTGCAGATTCTGTAGCATGGCAGTGCCGAGTATCCTGTATCACGAACTAAAGCACAAAAAGAGCAAGAAAATCAGTAATCTGCATCGTTGCAGTATCTGTTCTAAGGCATTCAAAGCTTGGAACAGTTTGAAGAATCATTTATTAATGAAGCACAAAGCTCCTAAGAAAAGATTAGACATGTTAAGGGCACTGTGTGAAATGAAATTTCAATCTAGAAGTGATTTTTATCAGCATTTACTTAGCCAATCGAAGGCCAAGCAGCGCAAGNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNNACGTCGCTCCACACTCGCATACTTAG
- Protein Sequence
- MLKNHVVDCRTLGVVQWDAKSKDCGDQAIKIFESRSPISSESSPEQVNPSSDRKDRTSRELNYLTNSDNDSLTNSSTKRRKNKRFEDQEQYICSTCKLRFDRQGDYKRHMIKHSDLRPYKCEICDKAFKRSSEVSNHTQIHRGIEYACEVCGFTTINKFSLRMHHRRVHQRDFRYRCDQCDKGFMSNYDLEDHKASHLGRKTFICEFCGNAYSQKSYLVAHKRVIHRIQKSAPKEYQCNICNKSFATEQNLRNHVGLHSQMFLCAQCGKKFATNHALKLHGRKHTGERPYECMVCSKAFARSAALRVHKLTHTGERPRCTIAETSLGQDRNDRLQFQDIVPASNPTIQNSMCLNVDIDSDENSQMTVTNNEDEVNDSTSTLGREIVDDSIVEPLKSVLVPVRVPVTKKINHMSVPFETRDESGLNTIKSILIPFRAEDGSASHEIKRIIVPMKSESSLSSEEEIAKKTLLTNEARSKQVNCKEEKEKENEKNQETSLGKRTRSREREKEEQKKKKVENEILDTLKNIYPFCQKCFKDEDEMQKHVLQTRKKPYSCDKYHKSYLSDVTLEEHQRTHDVVLFYRCSICQIQYKTATGLKNYQTREHSDIEPKYTCYCCKKQFKLKFDLNIYIHKLHMNTNYICRFCSMAVPSILYHELKHKKSKKISNLHRCSICSKAFKAWNSLKNHLLMKHKAPKKRLDMLRALCEMKFQSRSDFYQHLLSQSKAKQRKXXXXXXXXXXXXXXXXXVAPHSHT
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -