Basic Information

Insect: Bombus difficillimus
Gene Symbol: zfh1
Assembly: GCA_014737525.1
Location: JACXIT010000193.1:652253-661237[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 1.1 1e+02 3.8 1.8 2 23 91 113 91 113 0.90

2 7 8.2e-05 0.0077 16.8 0.6 2 23 132 153 131 153 0.96

3 7 5.3e-06 0.0005 20.5 7.8 1 23 162 184 162 184 0.99

4 7 0.00011 0.01 16.4 1.6 1 21 190 210 190 211 0.92

5 7 0.00021 0.02 15.5 4.5 1 23 656 678 656 678 0.94

6 7 6.7e-05 0.0063 17.1 7.1 1 23 684 706 684 706 0.98

7 7 0.0014 0.13 12.9 4.3 1 21 712 732 712 733 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	1.1	1e+02	3.8	1.8	2	23	91	113	91	113	0.90
2	7	8.2e-05	0.0077	16.8	0.6	2	23	132	153	131	153	0.96
3	7	5.3e-06	0.0005	20.5	7.8	1	23	162	184	162	184	0.99
4	7	0.00011	0.01	16.4	1.6	1	21	190	210	190	211	0.92
5	7	0.00021	0.02	15.5	4.5	1	23	656	678	656	678	0.94
6	7	6.7e-05	0.0063	17.1	7.1	1	23	684	706	684	706	0.98
7	7	0.0014	0.13	12.9	4.3	1	21	712	732	712	733	0.96

Sequence Information

Coding Sequence: ATGACCTTCGTCAGAAGGAATTTTCGTGAACGTTGCAGCGAGGACGAGGCAGCAGGTGTCGTGAACGCGGAGGTGGGCGGAGGTTGCGCGGCCGGGGCGCCAACCACAGGAAGTGGCGTTGGAGGTGGTAGCGGCACAGGTAGCGAAGCCGGTAGTGGTGGTGGAGGCGGTGGTGGAGCAGGAACAGGAACAGGAGGAGGCGGAGGAGGCGGCCGTGGTGGCGGCGGCAGCGGTGGCGGCGAGGGCGGATCGACGAAGCAGGGTGGCGAGAAGTGTCCCCAGTGCGGCTTCCTCTGTCGGGACGTCCACGTGCTTCAGCTCCATCTCGAGGACACGCACAAGACCCCGTACGCCATCGACAAGAACGATCTCAACGCTCAATTCCCTCAAGTGTCCTGCAGGGTGTGCAGCAAGACTTTTGCTAACGTCTACCGACTCCAGAGGCACATGATCAGCCATGATGAGAGTGCCGTGCTTCGTAAGTTTAAGTGTCCCCATTGCGAGAAAGCCTTCAAGTTTAAGCATCACCTCAAGGAACACCTCCGCATTCACAGCGGTGAAAAGCCATTCCTATGCAACAACTGCGGCAAACGCTTCTCTCATTCGGGCTCGTATTCGAGTCATATGACCTCGAAGAAGTGCCTGATAGTAAACTTAAAAAAATCCAGGCATACGAATGTGAGCAACGTGGATCGCGGGCCGAAAAAGGCGCAACAACCCCTGCCGCCGGGGCGGCGCGAGGTCGATCTGCTCGCGGCGAATAATAACACTTTCCTCCCTATTCTGCCGAAGCTTTCACCCTCGGATTATCAGGAGATACAACGGGAAGGAGCGGGTATTTACGACATGCCGACCCTTCTGCCACAAATGATGGGCTTCGGCAGCTACTTTCTGCAGGCATCCTTGGGCAAGATCTTAAATCAGCTACATTCCAAGAGATTGGACGAGGTAGCCGAGAAATTCGAATCTCATCGGGAGCTCATGAGCCCGTCGACGGCGGACTCTGAGGGCACGGAAGGCACAGAGGGTAAAGAATCACCAGCACCGACCGATCCTCAGGGTCTTGACGCGGTTCGACGTATCCTTGAAACGGTGAACACCTCCGTCACGAAGCAACTGCTCGAGGCGAACGTGAGGAAATTGTCCACCTCGCCGGCCACGATGAAACGAGAGTTCGAGGAGGATTATCAAGATCAAGACAGCGAGATATCCAGCGAGATGGCACATTATCCAGACTGGTCAGCAGCGGATCAATATGATTCGCAGAGTGAAGGTTTGGCTGCGAAGCTCGAGGACGTGAATCAACCCAGTGCGAAATCAGGTTACAAGAGAAAAACGGAGGATAGCTCGGAGGCGGACTCGGAGGACGAGGAGGATGGTACACAGACGCACAATGATAACGGAAGGAGAGTCAGGGCTAGATCGTTGATAGACGATGAGCAATTGGCTGTTCTCAAGGGTTACTATGCCATTAATCCTCGACCCAAGAAGGAGGAGATCATCATGATCGCCAATTACATCAATTTTCCTACTCGTGTCGTACAGGTTTGGTTCCAAAATTCCCGAGCGAGGGACCGACGAGAATCGAAGATACCACCTCTAGTACCATTGGCAAATCCGACCAGTCAGACCGCGTACGAACAACCATTAGATTTGTCGAAGAAAGAAGCTCTCACAGAGACGGCGTGCAAAGACAGTGAAACTGTTTGTGCAAAATTCACATCATCCTCTCCCGTTGAACCGAAAAACGATAATGCGCCATCGCATAATCAAGACGCGGATGATCTGGAGGATTCGCCACTCGTTATTGACGAAGAGACCACCGATTCTGTAGAAACGAAACGTACGGCCCCGATAGGGGGAGAAATTGTTCCGAAGAGTCAACCTCAGACAAATGTAAAGAACGAAAGTGAAAACGCGAGTCAACCAGAGGCTTCGCCGGCAGCGGAGATCGAGCAGGGTGTCTACTTCTGTGATCGGTGTGACAAAACATTCTCCAAGCACAGTTCCCTAGCAAGACACAAATATGAACATTCCGGGCAAAGGCCGTACAAATGCGTGGAGTGCCCAAGGGCGTTCAAGCACAAGCACCATCTGACCGAACACAAGCGACTGCACAGCGGCGAAAAGCCCTTCCAGTGCTCCAAGTGCCTCAAGCGCTTCTCTCACTCCGGCTCCTACAGCCAACACATGAATCATCGTTACTCTTACTGCAAGCCGTATAGAGAATAG
Protein Sequence: MTFVRRNFRERCSEDEAAGVVNAEVGGGCAAGAPTTGSGVGGGSGTGSEAGSGGGGGGGAGTGTGGGGGGGRGGGGSGGGEGGSTKQGGEKCPQCGFLCRDVHVLQLHLEDTHKTPYAIDKNDLNAQFPQVSCRVCSKTFANVYRLQRHMISHDESAVLRKFKCPHCEKAFKFKHHLKEHLRIHSGEKPFLCNNCGKRFSHSGSYSSHMTSKKCLIVNLKKSRHTNVSNVDRGPKKAQQPLPPGRREVDLLAANNNTFLPILPKLSPSDYQEIQREGAGIYDMPTLLPQMMGFGSYFLQASLGKILNQLHSKRLDEVAEKFESHRELMSPSTADSEGTEGTEGKESPAPTDPQGLDAVRRILETVNTSVTKQLLEANVRKLSTSPATMKREFEEDYQDQDSEISSEMAHYPDWSAADQYDSQSEGLAAKLEDVNQPSAKSGYKRKTEDSSEADSEDEEDGTQTHNDNGRRVRARSLIDDEQLAVLKGYYAINPRPKKEEIIMIANYINFPTRVVQVWFQNSRARDRRESKIPPLVPLANPTSQTAYEQPLDLSKKEALTETACKDSETVCAKFTSSSPVEPKNDNAPSHNQDADDLEDSPLVIDEETTDSVETKRTAPIGGEIVPKSQPQTNVKNESENASQPEASPAAEIEQGVYFCDRCDKTFSKHSSLARHKYEHSGQRPYKCVECPRAFKHKHHLTEHKRLHSGEKPFQCSKCLKRFSHSGSYSQHMNHRYSYCKPYRE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00086058;
90% Identity: iTF_00982854;
80% Identity: iTF_00219002;