Basic Information

Insect: Bombus difficillimus
Gene Symbol: -
Assembly: GCA_014737525.1
Location: JACXIT010000183.1:458266-462035[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 15 6.2e-06 0.00058 20.3 1.3 1 23 146 168 146 168 0.98

2 15 0.0008 0.075 13.7 1.0 3 23 176 196 175 196 0.99

3 15 7.4e-05 0.0069 16.9 0.0 1 23 318 340 318 340 0.98

4 15 0.52 49 4.8 0.1 1 23 346 369 346 369 0.96

5 15 2.8e-05 0.0026 18.3 2.0 1 23 395 417 395 417 0.98

6 15 1.6 1.5e+02 3.3 0.0 1 23 433 455 433 455 0.86

7 15 0.18 17 6.3 0.8 1 23 461 484 461 484 0.95

8 15 0.0036 0.34 11.6 3.0 2 19 492 509 492 513 0.95

9 15 0.00018 0.017 15.7 3.5 3 23 521 541 519 541 0.97

10 15 0.013 1.2 9.9 0.1 3 23 548 568 547 568 0.97

11 15 7.5e-06 0.0007 20.1 0.4 1 23 577 599 577 599 0.98

12 15 0.0032 0.3 11.8 0.2 3 23 607 627 605 627 0.97

13 15 0.0029 0.27 11.9 0.2 3 23 635 655 633 656 0.94

14 15 0.97 91 4.0 0.0 1 23 670 692 670 692 0.92

15 15 0.0023 0.21 12.3 0.0 1 20 1067 1086 1067 1089 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	15	6.2e-06	0.00058	20.3	1.3	1	23	146	168	146	168	0.98
2	15	0.0008	0.075	13.7	1.0	3	23	176	196	175	196	0.99
3	15	7.4e-05	0.0069	16.9	0.0	1	23	318	340	318	340	0.98
4	15	0.52	49	4.8	0.1	1	23	346	369	346	369	0.96
5	15	2.8e-05	0.0026	18.3	2.0	1	23	395	417	395	417	0.98
6	15	1.6	1.5e+02	3.3	0.0	1	23	433	455	433	455	0.86
7	15	0.18	17	6.3	0.8	1	23	461	484	461	484	0.95
8	15	0.0036	0.34	11.6	3.0	2	19	492	509	492	513	0.95
9	15	0.00018	0.017	15.7	3.5	3	23	521	541	519	541	0.97
10	15	0.013	1.2	9.9	0.1	3	23	548	568	547	568	0.97
11	15	7.5e-06	0.0007	20.1	0.4	1	23	577	599	577	599	0.98
12	15	0.0032	0.3	11.8	0.2	3	23	607	627	605	627	0.97
13	15	0.0029	0.27	11.9	0.2	3	23	635	655	633	656	0.94
14	15	0.97	91	4.0	0.0	1	23	670	692	670	692	0.92
15	15	0.0023	0.21	12.3	0.0	1	20	1067	1086	1067	1089	0.94

Sequence Information

Coding Sequence: ATGGATGTTGCTGGAGACTTAACACTACAGTGGGTGGAGGAGGTGGGAAATGTTATTCACGAAGAGGTAATATGTGGTTTAGAAGCACAACTTGTTGGAGCAGAAGAGGAAGTGATAGGAGCTTGCGAAGAAGTTACAATAGAAGAAACAGTAGAGTCAGTTCCCAATGTTACTTCTACGACAGGGTCAGAAATATTAATGGTACCACAATCCAACGACATGGAATCTATTTACATAGTTCCACAAGATCAAGGTCATGATTATTTGAACATACAGGTTACAGAAGAAGTAATTGCAGATAATTGGGATAGATCTGGTCCAGAAGATGGAGTTGAGATATCAGAAGTAAAAGTATCTCATGAAAATTTGCTGGAATATGATGATATGGAGATACCATTGCCAATTGATCAAGATTCGTATACAAATAGTAGACCTTATCCATGTGATTTCTGCAGCAGAAGGTTCAGAAAGAAAGCAAACTTAATGAATCATATGGTGACACATCAAACAGATCGACCTCATGGTTGTAATTTATGTGGAGCACGTTATGCAAGAAAATGTGATCTTATGAATCATTTAAAGATTCATGCTTATGCACCACCACGAGATGGTTTAGAGGATGATTTAAACGATGATGATTCATTGGCACCAGAAGAAGAGGAATCTACCAAAGGTAGACGTAAAAAGGTACAATCAAGTGTACCAAGAAAACGCAAAAATAATTCTATTTCAAAACGCAATATGGAAGATAATAAAATGGAAATGGGCAAGTACGTCAGTAAATCTTATGATTATGTTGATGAAGATATGCGTCTTTTGGAGGAAATGACTAGTAGAAATTCTGCGCGCAGTAGTAACTATGCTTCAAGCTCAAGATGGACTGAACAGATGTCACCTGTATCAAATGAAGTTCAAACACCACGGTGGCCTATAACTGATCCAACAAAACCATATGTGTGTCAGTATTGTGGTGTTGGTTTTGCAAGGGAAAAAGCACTTGCTTCTCATGCACGCATACATGGTGGTGATAGTCCATTTGAATGTACGTCTTGTGGTGATATGTTTTGGGATGTTAATAGTTTAAGAGAACATGTTCGTATCAAACATGGTGGTACAGTACAATCTGATACAGAGGAATATGATAATGATGCCACATATACAGGAGATGAAAGATTTGGGGAATTCTATTGTAATACTTGTGGTGTTCCTTTTCATCGTTTGGATTTACTTAAACGCCATCAAAAGATTCATGTCAAACAGGAGGCTGCTGATATGATGGAAGGTCCAAGTCGACTTCATGTTTGTAATGTTTGTGGTGAATGGTTTGAGGAAGCTTTGGCATTGTTAGCACATGCTGAACTTCATGCTAGATCACCCGGTCATCGATGTTTACTGTGTGGGGAAAGATGTCGTGATGATGCTGAAGTTGCTGAACATGTTCGACAAAATCATGCCCAAGATGCTCCACCAAATACATGTACTCTTTGTGGAAAAACGTGTAAAGATAAACGCAGTTTATTAAAGCATTCGTGGGTTCATAATGTCGATAAAACTTTTGGATGTACAAAATGTGGGAAACGTTTCCATAGCAAAGCTAGATTACGAAGACATATGGTATCACACCGCAATAAGATGGTAGCTTGTGACGAGTGTGGAGAAGAGTTTCCTGACGGTAGAGCTTTGGTTAGCCACCGTCATTCACATAATAAAGATCTAGGTGGTCGTTCTTTTCCGTGCCGAGAATGTGGAAAAACATTTGGTAGTCGTAGTTCACAACAAATTCATATTCGCATTCACACTGGAGAAAGACCATATGGTTGTAGATTTTGTTGGAAAGCATTTGCTGATGGTGGAACTTTAAGAAAACACGAACGTATCCACACAGGAGAAAAGCCATATGGATGCGCAATTTGTCCACGTGCTTTTAATCAAAGAGTTGTTCTTAGAGAACACGTTCGTGCTCATCATTCAGGTCCTGATCCAAAATGTGTAGGTAGTATTACACCATACTTATGTAAAGTATGTGGTGATGCATATGGAACATCGGAAGAAATAGTTGCTCATATTGTGCAACATTGTGATGATAATACCGCATTAAGACGTCAACCACAAACTGGACCACGTAAATATAAAAGAAGACGTAAATTAAAAACCCATGAAACCAATACGATGTTGCGTATGACTGAGCAGTATGATATGGAAGGAGGTTCTGATTCAGATGATAATACAAAAAGAAAGCTTGGAAGAAAAAATAAGCAACATCGATCGAACGTTGAAGAAGGTTATCAGAATGTTCTTAAAAGTTTTGAAAACTCTTTACAAAATATAAATTCAATCGTCAGCAATTCAAAGTTAAATCCTGGAAAATCGAAGCTTTCTAAGAAGAAGCTTAGGAAAGAAGAAAAAAAAAGTGAAGCTGAAGCTTCGTGTCAACCTGGTAGACCAAAAATGATTCATACGCAAAAAACAAGAGTGCCTGTAGAAATTGGTGGTGATGGAGTTAAAAAGGGACAGAAAACTAAAACAATGGTAACAAGGACACCTAAAATGATGCCACAAGAGCATAAGTTAGGTGTTTTCCCGGGCGGGGAAAGGAACAGACCAAGAACAAAAAACGTTAGTTATCACATTGAAGGGAAACTTCAACCAACACCTGCAACATTCCCAAAACAAAAGGAAGAAACTTTATTACCTCCAACACCAATACATCATCAATCGCCATTAACCAATATAAAAATAGAACCTAACTTACAAAAAACGTCAAATAATAATCACAGAAATAATAATGGCAATATTCTTGCTATTAATAATGAAAAAATGGAGCCAACACCTAGAAAAAAATCAGGTGTCTTGAGAAAAATTAAAAAACAGAAAGATGTAATTAAGCAAGAACCAATAGATATTGACCACGAGGAAATACAAAATAATAATAATACAGAAAATATGGATTCAGAAAGATTAATGGATCATTCAGTGGATGGAAGTAATTTAGAAGTCGCATTCGAGGCAAGTGTTACAACCGAGGAAGAAAATATACTTCCTGATGTAGGTGAAGCAAATAATACCGAAGATGTGGGTACTGGAAATGTAAAACTTAGTGTAAAAGTTGAGTCAACGCCTCAAAGAATGTTGGCTGTTCATAGCGTTATAGCCCCTGTGGATGATATTCCAGAAACTATAATACCAGATGCTGTAGAATATACATGCGAAATGTGTTCTGCAGTATTTTCCAGCCGAGCAGAATTATTGGTCCACGTTCCAATACACATTTGA
Protein Sequence: MDVAGDLTLQWVEEVGNVIHEEVICGLEAQLVGAEEEVIGACEEVTIEETVESVPNVTSTTGSEILMVPQSNDMESIYIVPQDQGHDYLNIQVTEEVIADNWDRSGPEDGVEISEVKVSHENLLEYDDMEIPLPIDQDSYTNSRPYPCDFCSRRFRKKANLMNHMVTHQTDRPHGCNLCGARYARKCDLMNHLKIHAYAPPRDGLEDDLNDDDSLAPEEEESTKGRRKKVQSSVPRKRKNNSISKRNMEDNKMEMGKYVSKSYDYVDEDMRLLEEMTSRNSARSSNYASSSRWTEQMSPVSNEVQTPRWPITDPTKPYVCQYCGVGFAREKALASHARIHGGDSPFECTSCGDMFWDVNSLREHVRIKHGGTVQSDTEEYDNDATYTGDERFGEFYCNTCGVPFHRLDLLKRHQKIHVKQEAADMMEGPSRLHVCNVCGEWFEEALALLAHAELHARSPGHRCLLCGERCRDDAEVAEHVRQNHAQDAPPNTCTLCGKTCKDKRSLLKHSWVHNVDKTFGCTKCGKRFHSKARLRRHMVSHRNKMVACDECGEEFPDGRALVSHRHSHNKDLGGRSFPCRECGKTFGSRSSQQIHIRIHTGERPYGCRFCWKAFADGGTLRKHERIHTGEKPYGCAICPRAFNQRVVLREHVRAHHSGPDPKCVGSITPYLCKVCGDAYGTSEEIVAHIVQHCDDNTALRRQPQTGPRKYKRRRKLKTHETNTMLRMTEQYDMEGGSDSDDNTKRKLGRKNKQHRSNVEEGYQNVLKSFENSLQNINSIVSNSKLNPGKSKLSKKKLRKEEKKSEAEASCQPGRPKMIHTQKTRVPVEIGGDGVKKGQKTKTMVTRTPKMMPQEHKLGVFPGGERNRPRTKNVSYHIEGKLQPTPATFPKQKEETLLPPTPIHHQSPLTNIKIEPNLQKTSNNNHRNNNGNILAINNEKMEPTPRKKSGVLRKIKKQKDVIKQEPIDIDHEEIQNNNNTENMDSERLMDHSVDGSNLEVAFEASVTTEEENILPDVGEANNTEDVGTGNVKLSVKVESTPQRMLAVHSVIAPVDDIPETIIPDAVEYTCEMCSAVFSSRAELLVHVPIHI

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_01424531;
90% Identity: iTF_01420417;
80% Identity: -