Bdif004768.1


Basic Information
Transcription Factor Domain
Sequence Information
Similer Transcription Factors

Basic Information

Insect
Bombus difficillimus
Gene Symbol
gtf3a
Assembly
GCA_014737525.1
Location
JACXIT010000119.1:82134-84965[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 16 3.8e-05 0.0036 17.8 0.1 2 23 233 254 232 254 0.97
2 16 1.2 1.2e+02 3.6 0.9 1 23 286 308 286 308 0.96
3 16 0.00015 0.014 16.0 1.2 3 23 317 338 316 338 0.98
4 16 0.0015 0.14 12.8 2.0 1 23 345 368 345 368 0.95
5 16 5.3e-05 0.005 17.4 0.7 1 23 374 397 374 397 0.94
6 16 0.73 68 4.4 2.5 2 23 405 425 405 425 0.94
7 16 7.8e-08 7.3e-06 26.3 2.1 2 23 431 452 430 452 0.97
8 16 1.3e-06 0.00012 22.5 0.2 1 23 458 480 458 480 0.99
9 16 0.00031 0.029 15.0 2.4 2 23 492 514 491 514 0.95
10 16 0.0044 0.41 11.3 2.5 1 23 520 543 520 543 0.96
11 16 0.014 1.3 9.8 3.8 3 23 565 586 564 586 0.95
12 16 0.00065 0.061 14.0 1.4 2 23 593 615 592 615 0.96
13 16 5.6e-05 0.0052 17.3 2.4 2 23 623 644 622 644 0.97
14 16 0.00067 0.063 13.9 2.3 1 23 650 673 650 673 0.96
15 16 0.18 17 6.3 3.2 2 23 680 701 679 701 0.96
16 16 0.0053 0.5 11.1 2.6 1 23 707 729 707 729 0.98

Sequence Information

Coding Sequence
TTAAAACGATATGAAACATTAGTTACAAAAGAAAAAGATTTATTTCCAGAACGAACAAAAAAGTTAGAAATAAGAGAGCAGATTATAGAAGAACAAATAGAAGAATACAAGAAAAAGCGAGAAAAAGTATTAGGTGGACACGCCAATATTGTTGCACCTCCAAAATTTGAGGAATCTCGTTACTTTAAGCGTAATGAAAGTCAAGATAATCAAAGATCTTTTACACATATAGAAAATGATTCTGCTGTAAACATACAGTTTAATAAAGATGATAGCGAATTTAATGCAACTATTACAATTGAAGATGATGCTATAGAAATTGCAGAATCAGCCAAAGAAAAGTCTACAAATGAAAAAGCATATGTAAATACTGAAGAATATTTATCACGTTTGGCAAAGCTTAAATTGAAATGGGAAGAAGCAAAAAAGAAAAAAGAATATCTTCAAAAAGAACTTGATGAATCTTATACAGAAGGAAATATTGAAAAGTTAGCAAGAATTTTAGGGGAAAAAAAGAAAAATTTGCAAGACTTTCAAGATTATTTAAAACAACGTAAAATTGTAATTACAAGATTAAAAGATGAGGATATTATTTCTCTTTATGAAGACAGAAATAATGCAGTCCTTAAAAACAACTTACCTGACTTAATAGATGAAAGTCAACCAGCAGATTATATTCCAGAAGAACATTATTTAGAATGTGATTATTGTCCAGAAACATTTGCATCTAAAGAAGTTCTTGAAGAACATTTGAGATCGCATGACTATAAAATTATGCATTTTTGTGAAGATTGCATGCAAGAATTTCCAACAAATAAAGCAAAACGAAATCATAATGTGCTTTGTCCAAAAAAATTCGTATGTCAACAATGCAACTTGGAGTTAGGTTCAAAAGGAAAAAAGCGTCAGCATGAACAAAAACATTGTGATAATAAGTTTGGACAATTATGTGATGTATGTGGTGAAAAATTTAAACATCAAGGAACATTAGATCAACATGTCAAAACACAACACATGAATTGGGAGAAAATATATCAATGTCCAAAGTGTCCTAAAAAGTTTGCATTCAAACAAAAACTTAGCTTTCATTTGAAATCTGTACACACAACTTTAAGAGCCTATTTGTGTGAAGACTGTGGAGCTGATTTTAAAAATCCTGCAAGTCTTAGACATCATAGAATACGTAAACATCAACCTGTAAGTAATAAGAGAGAATGCCCAGTTTGCCATAAATTAGTACCATTTTATAGCCTTTCTAAACATATGCATACTCATAAAGCATATACTATTCAGTGTCCACATTGTGACAAAATGTTTAAAAATAGTTCAACTTTAAAGCAACATGTAAGAATTCATGAAGATCAACGTCAATATCGATGTGATACTTGTGGTGTTGGATTTAATAGAAGAGATGGATTAAGGTTACACATGAGAGTACATGAAAAGACCGATAGTAGAGGATTAAAAGAATGTTCATGTCAAGTATGTGGTGAAAAGTTTCCAAATCATTCAACACTTGTTATACATAGGAACCGAGTTCATAAGGATGGTAGACAATACACTTGTCATATATGTAATAGATCAATGATTTCAACTAGATCATTAGAGTGGCATATGTCTCATATACACAATGAAACACTTCCTGGTGTAAAGGAAGGGATAGATGGGGCACCAGAAAAAAGAAGGGCATCATGTTATCATTGTAATAAGACATTCAAAACAGAAATGATTTTGAGAACACATATTAAAAACACACATATGGAGAAAGATCCTATGAAATGTTTAGATTGTGAATTAACATTTACTTCCGAAGTGAGGTTAAGACATCATATGATGGTCACACATAACAGATTAGAAGGAACTTTACAGTGCCCACATTGTTCAAAGAGATTTGTGAATCAACTCAGATTAAAAACTCATATGATATCTCATTCTGAAGAAAGGCCATACACTTGTGAAATCTGTGGGTTTAATTTGAAAACTAAGATACAGTTGATTAAACATCATCAAAATAGGCACAGCGATGAAAGACCTTTACAGTGTAGATATTGTCCTTGGAGATGTAAACAAGTTAGTGCACTTGTATGTCATGAAAGAACTCATACAAATGAACGACCATATTCTTGCAGTGTATGTAGGCAACGTTTTAAATATTTAGGTGATAAAAATAAACATGAAAGACGACATGAAAGCTTAGGAGGATCTGGATTTAAAAGGATAATACTTAGTCGAAATAGTAAACCTAAACTATTAGAAGATTCTTCTTGTTCTGAACATGAAAGTTTACATAATATAAAGTGTCAAGTTCCTGAAAGTGAATATCAAGAACAGACAGATCAACAATTTGAAGAAGAACAAATAGTTAAGTTTGAAGAAGAACAAATAGTTAAATTTGAAGAAGAACAGATTAAATTTGAAGAACAAGAAATAACAGAAGAATATGAACAAGTATATGAACAGGAATATGAAGAGACATCCAGAGAAGCTTCTGATGCAGCGGAAGTTATAATGAATATGGAAGATACAACAGTTTACACAGAAGAAGTGACTGCAGATAACATTGAACCTACAGAAATTATGGCAGATGAAATAATGACAAATGAAATATTACAATCAGGTGCTGTAGTTCACTTGCAACAAGAAGATGATTCAGGGAAAATACAAGTGATTCCAGTGATGTTATCTTTACCTGATTTATCCGATGCAAATACAGAGGTCAATTTAGCTACTGCATCCATTATGTATAATAATTGA
Protein Sequence
LKRYETLVTKEKDLFPERTKKLEIREQIIEEQIEEYKKKREKVLGGHANIVAPPKFEESRYFKRNESQDNQRSFTHIENDSAVNIQFNKDDSEFNATITIEDDAIEIAESAKEKSTNEKAYVNTEEYLSRLAKLKLKWEEAKKKKEYLQKELDESYTEGNIEKLARILGEKKKNLQDFQDYLKQRKIVITRLKDEDIISLYEDRNNAVLKNNLPDLIDESQPADYIPEEHYLECDYCPETFASKEVLEEHLRSHDYKIMHFCEDCMQEFPTNKAKRNHNVLCPKKFVCQQCNLELGSKGKKRQHEQKHCDNKFGQLCDVCGEKFKHQGTLDQHVKTQHMNWEKIYQCPKCPKKFAFKQKLSFHLKSVHTTLRAYLCEDCGADFKNPASLRHHRIRKHQPVSNKRECPVCHKLVPFYSLSKHMHTHKAYTIQCPHCDKMFKNSSTLKQHVRIHEDQRQYRCDTCGVGFNRRDGLRLHMRVHEKTDSRGLKECSCQVCGEKFPNHSTLVIHRNRVHKDGRQYTCHICNRSMISTRSLEWHMSHIHNETLPGVKEGIDGAPEKRRASCYHCNKTFKTEMILRTHIKNTHMEKDPMKCLDCELTFTSEVRLRHHMMVTHNRLEGTLQCPHCSKRFVNQLRLKTHMISHSEERPYTCEICGFNLKTKIQLIKHHQNRHSDERPLQCRYCPWRCKQVSALVCHERTHTNERPYSCSVCRQRFKYLGDKNKHERRHESLGGSGFKRIILSRNSKPKLLEDSSCSEHESLHNIKCQVPESEYQEQTDQQFEEEQIVKFEEEQIVKFEEEQIKFEEQEITEEYEQVYEQEYEETSREASDAAEVIMNMEDTTVYTEEVTADNIEPTEIMADEIMTNEILQSGAVVHLQQEDDSGKIQVIPVMLSLPDLSDANTEVNLATASIMYNN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
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90% Identity
-
80% Identity
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