Basic Information

Insect: Bombus cullumanus
Gene Symbol: zfh1
Assembly: GCA_014737535.1
Location: JACXIX010000013.1:7620638-7630766[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.98 91 3.9 1.8 2 23 81 103 81 103 0.90

2 7 7.5e-05 0.007 16.8 0.6 2 23 122 143 121 143 0.96

3 7 4.8e-06 0.00045 20.6 7.8 1 23 152 174 152 174 0.99

4 7 9.7e-05 0.0091 16.5 1.6 1 21 180 200 180 201 0.92

5 7 0.00019 0.018 15.5 4.5 1 23 646 668 646 668 0.94

6 7 6.1e-05 0.0057 17.1 7.1 1 23 674 696 674 696 0.98

7 7 0.0013 0.12 12.9 4.3 1 21 702 722 702 723 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.98	91	3.9	1.8	2	23	81	103	81	103	0.90
2	7	7.5e-05	0.007	16.8	0.6	2	23	122	143	121	143	0.96
3	7	4.8e-06	0.00045	20.6	7.8	1	23	152	174	152	174	0.99
4	7	9.7e-05	0.0091	16.5	1.6	1	21	180	200	180	201	0.92
5	7	0.00019	0.018	15.5	4.5	1	23	646	668	646	668	0.94
6	7	6.1e-05	0.0057	17.1	7.1	1	23	674	696	674	696	0.98
7	7	0.0013	0.12	12.9	4.3	1	21	702	722	702	723	0.96

Sequence Information

Coding Sequence: ATGTTTATGGTATATCTGAGTCGTATAAAGTGCAGTCTTCAAGGTTGCAGCGAGGACGAGGCAGCAGGTGTCGTGAACGCGGAGGTGGGCGGAGGTTGCGCGGCCGGGGCGCCAACCACAGGAAGTGGCGTTGGAGGTGGTAGCGGCACAGGAACAGGAACAGGAGGAGGCGGAGGAGGCGTTCGTGGTGGCGGCTGCAGCGGTGGCGGCGAGGGCGGATCGACGAAGCAGGGTGGCGAGAAGTGTCCCCAGTGCGGCTTCCTCTGTCGGGACGTCCACGTGCTTCAGCTCCATCTCGAGGACACGCACAAGACCCCGTACGCCATCGACAAGAACGATCTCAACGCTCAATTCCCTCAAGTGTCCTGCAGGGTGTGCAGCAAGACTTTTGCTAACGTCTACCGACTCCAGAGGCACATGATCAGCCATGATGAGAGTGCCGTGCTTCGTAAGTTTAAGTGTCCCCATTGCGAGAAAGCCTTCAAGTTTAAGCATCACCTCAAGGAGCACCTCCGCATTCACAGCGGTGAAAAGCCATTCCTATGCAACAACTGCGGCAAGCGTTTTTCCCATTCGGGCTCGTATTCGAGTCATATGACCTCGAAGAAGTGCCTGATAGTAAATTTAAAAAAATCCAGGCATACGAATGTGAGCAACGTGGATCGCGGGCCGAAAAAGGCGCAACAACCCCTGCCGCCGGGGCGGCGCGAGGTCGATCTGCTCGCGGCGAATAATAACACTTTCCTCCCTATTCTGCCGAAGCTTTCACCCTCGGATTATCAGGAGATACAACGGGAAGGAGCGGGCATTTACGATATGCCGACCCTTCTACCACAAATGATGGGCTTCGGCAGCTACTTTCTGCAGGCATCTTTGGGCAAGATCTTAAATCAGCTACATTCCAAGAGATTGGACGAGGTAGCCGAGAAATTCGAATCTCATCGGGAGCTCATGAGCCCGTCGACGGCGGACTCTGAGGGCACAGAAGGCACAGAGGGTAAAGAATCACCAGCACCGACCGATCCTCAGGGTCTTGACGCGGTTCGACGTATCCTTGAAACGGTGAACACCTCCGTCACGAAGCAACTGCTCGAGGCGAACGTGAGGAAATTGTCCACCTCGCCGGCCACGATGAAACGAGAGTTCGAGGAGGATTATCAAGATCAAGACAGCGAGATGTCCAGCGAGATGGCACATTATCCAGACTGGTCAGCAGCGGATCAATATGACTCGCAGAGTGAAGGTTTGGCGGCGAAGCTCGAGGACGTGAATCAACCCAATGCGAAATCAGGTTACAAGAGAAAAACGGAGGATAGCTCGGAGGCGGACTCGGAGGACGAGGAGGATGGTACACAGACGCACAATGATAACGGAAGGAGAGTCAGGGCTAGATCGTTGATAGACGATGAGCAATTGGCTGTTCTCAAGGGTTACTATGCCATTAATCCTCGACCCAAGAAGGAGGAGATCATCATGATCGCTAATTACATCAATTTTCCTACTCGTGTCGTACAGGTTTGGTTCCAAAATTCCCGAGCAAGGGACCGACGAGAATCGAAGATACCACCTCTAGTACCATTAGCAAATCCGACCAGTCAGACCGCGTACGAACAACCATTAGATTTATCGAAGAAAGAAGCTCTCACAGAGACGGCGTGCAAAGACAGTGAAACTGCCTGTGCAAAATTCACATCATCGTCTCCCGTTGAACCGAAAAACGATAATGCGCCGTCGCATAATCAAGACGCGGATGATCTGGAGGATTCGCCACTCGTTATTGACGAAGAGACCACCGATTCTGTAGAAACGAAACGTACGGCCCCAATGGGGGGAGAAATTGTTCCGAAGAGTCAACCTCAGACAAATGTAAAGAACGAAAGTGAAAACGCGAGTCAACCAGAGGCTTCGCCAGCAGCGGAGATCGAGCAGGGTGTCTACTTCTGTGATCGGTGTGACAAAACATTCTCCAAGCACAGTTCCCTAGCAAGACACAAATATGAACATTCCGGGCAAAGGCCGTACAAATGCGTGGAGTGCCCAAGGGCGTTCAAGCACAAGCACCATCTGACCGAACACAAGCGACTGCACAGCGGCGAAAAGCCCTTCCAGTGCTCCAAGTGCCTCAAGCGCTTCTCTCACTCCGGCTCCTACAGCCAACACATGAATCATCGTTACTCTTACTGCAAGCCGTATAGAGAATAG
Protein Sequence: MFMVYLSRIKCSLQGCSEDEAAGVVNAEVGGGCAAGAPTTGSGVGGGSGTGTGTGGGGGGVRGGGCSGGGEGGSTKQGGEKCPQCGFLCRDVHVLQLHLEDTHKTPYAIDKNDLNAQFPQVSCRVCSKTFANVYRLQRHMISHDESAVLRKFKCPHCEKAFKFKHHLKEHLRIHSGEKPFLCNNCGKRFSHSGSYSSHMTSKKCLIVNLKKSRHTNVSNVDRGPKKAQQPLPPGRREVDLLAANNNTFLPILPKLSPSDYQEIQREGAGIYDMPTLLPQMMGFGSYFLQASLGKILNQLHSKRLDEVAEKFESHRELMSPSTADSEGTEGTEGKESPAPTDPQGLDAVRRILETVNTSVTKQLLEANVRKLSTSPATMKREFEEDYQDQDSEMSSEMAHYPDWSAADQYDSQSEGLAAKLEDVNQPNAKSGYKRKTEDSSEADSEDEEDGTQTHNDNGRRVRARSLIDDEQLAVLKGYYAINPRPKKEEIIMIANYINFPTRVVQVWFQNSRARDRRESKIPPLVPLANPTSQTAYEQPLDLSKKEALTETACKDSETACAKFTSSSPVEPKNDNAPSHNQDADDLEDSPLVIDEETTDSVETKRTAPMGGEIVPKSQPQTNVKNESENASQPEASPAAEIEQGVYFCDRCDKTFSKHSSLARHKYEHSGQRPYKCVECPRAFKHKHHLTEHKRLHSGEKPFQCSKCLKRFSHSGSYSQHMNHRYSYCKPYRE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00086058;
90% Identity: iTF_00982854;
80% Identity: iTF_00217646;