Basic Information

Insect: Bombus consobrinus
Gene Symbol: zfh1
Assembly: GCA_014737455.1
Location: JACXIU010000030.1:2553519-2583775[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.98 79 3.9 1.8 2 23 61 83 61 83 0.90

2 7 7.5e-05 0.006 16.9 0.6 2 23 102 123 101 123 0.96

3 7 4.8e-06 0.00039 20.6 7.8 1 23 132 154 132 154 0.99

4 7 9.7e-05 0.0078 16.5 1.6 1 21 160 180 160 181 0.92

5 7 0.00019 0.015 15.6 4.5 1 23 626 648 626 648 0.94

6 7 6.1e-05 0.0049 17.1 7.1 1 23 654 676 654 676 0.98

7 7 0.0013 0.1 13.0 4.3 1 21 682 702 682 703 0.96

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.98	79	3.9	1.8	2	23	61	83	61	83	0.90
2	7	7.5e-05	0.006	16.9	0.6	2	23	102	123	101	123	0.96
3	7	4.8e-06	0.00039	20.6	7.8	1	23	132	154	132	154	0.99
4	7	9.7e-05	0.0078	16.5	1.6	1	21	160	180	160	181	0.92
5	7	0.00019	0.015	15.6	4.5	1	23	626	648	626	648	0.94
6	7	6.1e-05	0.0049	17.1	7.1	1	23	654	676	654	676	0.98
7	7	0.0013	0.1	13.0	4.3	1	21	682	702	682	703	0.96

Sequence Information

Coding Sequence: ATGAGCATGACTCTCGTCCGCAATACGTTCAAAGGTTGCAGCGAGGACGAGGCAGCAGGTGTCGTGAACGCGGAGGTGGGCGGAGGTTGCGCGGCCGGGGCGCCAACCACAGGAAGAGGCGTCCGTGGTGGCGGCGGCAGCGGTGGCGGCGAGGGCGGATCGACGAAGCAGGGTGGCGAGAAGTGTCCCCAGTGCGGCTTCCTCTGTCGGGACGTCCACGTGCTTCAGCTCCATCTCGAGGACACGCACAAGACCCCGTACGCCATCGACAAGAACGATCTCAACGCTCAATTCCCTCAAGTGTCCTGCAGGGTGTGCAGCAAGACTTTTGCTAACGTCTACCGACTCCAGAGGCACATGATCAGCCATGATGAGAGTGCCGTGCTTCGTAAGTTTAAGTGTCCCCATTGCGAGAAAGCCTTCAAGTTTAAGCATCACCTCAAGGAGCACCTCCGCATTCATAGCGGTGAAAAGCCATTCCTATGCAACAACTGCGGCAAGCGCTTCTCCCATTCGGGTTCGTATTCGAGTCATATGACCTCGAAGAAGTGCCTGATAGTAAACTTAAAGAAATCCAGGCATACGAATGTGAGCAACGTGGATCGCGGGCCGAAAAAAGCGCAACAACCCCTGCCGCCGGGGCGGCGCGAGGTCGATCTGCTCGCGGCGAATAATAACACTTTCCTCCCTATTCTGCCGAAGCTTTCACCCTCGGATTATCAGGAGATACAACGGGAAGGAGCGGGTATTTACGACATGCCGACCCTTCTGCCACAAATGATGGGCTTCGGCAGCTACTTTCTGCAGGCATCCTTGGGCAAGATCTTAAATCAGCTACATTCCAAGAGATTGGACGAGGTAGCCGAGAAATTCGAGTCTCATCGGGAGCTCATGAGCCCGTCGACGGCGGACTCTGAGGGCACGGAAGGCACAGAGGGTAAAGAATCACCAGCACCGACCGATCCTCAGGGTCTTGACGCGGTTCGACGTATCCTTGAAACGGTGAACACCTCCGTCACGAAGCAACTGCTCGAGGCGAACGTGAGGAAATTGTCCACCTCGCCGGCCACGATGAAACGAGAGTTCGAGGAGGATTATCAAGATCAAGACAGCGAGATGTCCAGCGAGATGGCACATTATCCAGACTGGTCAGCAGCGGATCAATATGATTCGCAGAGTGAAGGTTTGGCGGCGAAGCTCGAGGACGTGAATCAACCCAGTGCGAAATCAGGTTACAAGAGAAAAGCGGAGGATAGCTCGGAGGCGGACTCGGAGGACGAGGAGGATGGTACACAGACGCACAATGATAACGGAAGGAGAGTCAGGGCTAGATCGTTGATAGACGATGAGCAATTGGCTGTTCTCAAGGGTTACTATGCCATTAATCCACGACCCAAGAAGGAGGAAATCATCATGATCGCCAATTACATCAATTTTCCTACTCGTGTCGTACAGGTTTGGTTCCAAAATTCCCGAGCAAGGGACCGACGAGAATCGAAGATACCACCTCTAGTACCATTGGCAAATCCGACCAGTCAGACCGTGTACGAACAACCATTAGATTTGTCGAAGAAAGAAGCTCTCACAGAGACGGCGTGCAAAGACAATGAAACTGTTTGTGCAAAATTCACATCATCGTCTCCCGTTGAACCGAAAAACGATAATGCGCCGTCGCATAATCAGGACGCAGATGATCTGGAGGATTCGCCACTCGTTATTGACGAAGAGACCACCGATTCTGTAGAAACGAAACGTACGGCCCCAATGGGGGGAGAAATTGTTCCGAAGAGTCAACCTCAGACAAATGTAAAGAACGAAAGTGAAAACGCGAGTCAACCAGAGGCTTCGCCAGCAGCGGAGATCGAGCAGGGTGTCTACTTCTGTGATCGGTGTGACAAAACATTCTCCAAGCACAGTTCCCTAGCAAGACACAAATATGAACATTCCGGGCAAAGGCCGTACAAATGCGTGGAGTGCCCAAGGGCGTTCAAGCACAAGCACCATCTGACCGAACACAAGCGACTGCACAGCGGCGAAAAGCCCTTCCAGTGCTCCAAGTGCCTCAAGCGCTTCTCTCACTCCGGCTCCTACAGCCAACACATGAATCATCGTTACTCTTACTGCAAGCCGTATAGAGAATAG
Protein Sequence: MSMTLVRNTFKGCSEDEAAGVVNAEVGGGCAAGAPTTGRGVRGGGGSGGGEGGSTKQGGEKCPQCGFLCRDVHVLQLHLEDTHKTPYAIDKNDLNAQFPQVSCRVCSKTFANVYRLQRHMISHDESAVLRKFKCPHCEKAFKFKHHLKEHLRIHSGEKPFLCNNCGKRFSHSGSYSSHMTSKKCLIVNLKKSRHTNVSNVDRGPKKAQQPLPPGRREVDLLAANNNTFLPILPKLSPSDYQEIQREGAGIYDMPTLLPQMMGFGSYFLQASLGKILNQLHSKRLDEVAEKFESHRELMSPSTADSEGTEGTEGKESPAPTDPQGLDAVRRILETVNTSVTKQLLEANVRKLSTSPATMKREFEEDYQDQDSEMSSEMAHYPDWSAADQYDSQSEGLAAKLEDVNQPSAKSGYKRKAEDSSEADSEDEEDGTQTHNDNGRRVRARSLIDDEQLAVLKGYYAINPRPKKEEIIMIANYINFPTRVVQVWFQNSRARDRRESKIPPLVPLANPTSQTVYEQPLDLSKKEALTETACKDNETVCAKFTSSSPVEPKNDNAPSHNQDADDLEDSPLVIDEETTDSVETKRTAPMGGEIVPKSQPQTNVKNESENASQPEASPAAEIEQGVYFCDRCDKTFSKHSSLARHKYEHSGQRPYKCVECPRAFKHKHHLTEHKRLHSGEKPFQCSKCLKRFSHSGSYSQHMNHRYSYCKPYRE

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00086058;
90% Identity: iTF_00982854;
80% Identity: iTF_00216966;