Basic Information

Insect: Bombus confusus
Gene Symbol: Bcl11b
Assembly: GCA_014737475.1
Location: JACXIV010000033.1:2788798-2794224[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 6 0.0048 0.37 11.1 0.2 2 23 21 43 20 43 0.95

2 6 1.5e-07 1.2e-05 25.3 1.5 1 23 356 378 356 378 0.98

3 6 0.0033 0.25 11.7 0.2 2 23 399 421 398 421 0.96

4 6 8.4e-08 6.5e-06 26.1 2.9 2 23 624 645 623 645 0.97

5 6 6e-06 0.00046 20.3 3.3 1 23 651 673 651 673 0.99

6 6 2.7e-05 0.0021 18.2 0.4 1 22 681 702 681 702 0.97

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	6	0.0048	0.37	11.1	0.2	2	23	21	43	20	43	0.95
2	6	1.5e-07	1.2e-05	25.3	1.5	1	23	356	378	356	378	0.98
3	6	0.0033	0.25	11.7	0.2	2	23	399	421	398	421	0.96
4	6	8.4e-08	6.5e-06	26.1	2.9	2	23	624	645	623	645	0.97
5	6	6e-06	0.00046	20.3	3.3	1	23	651	673	651	673	0.99
6	6	2.7e-05	0.0021	18.2	0.4	1	22	681	702	681	702	0.97

Sequence Information

Coding Sequence: ATGTTGCAGGTATTTAACCGAGACCGTCTACATTATCCTGTTTCAGAACCACGATGGCTGCAGTGCTCGCAGTGTTCCAGAAGACTATCCTCAGCGTGGGAGCTGCTCCAGCACGTACAAAGCGTCCACGGCGCCCGTCTTTACACTTCCCCGTCGTCATCGACGAACTCCTCGTCGAACACACCCGCGCCAAGTCCACCAACGCCCACACCCACCCACACGCATCACCTGAGCCCACCCAACCACCTGAATCTAAGCAGTAAATCCACCGGAAGCTCATCCACGGGAAACTCATCTGGCGGCACGAGTTCCAGCGGTAACAGCAGTGGACGACAACAACTTCAATCCTCGGCGTCCCTTGTTGGCGATCCGCTTCACAGTTTTCTAAGGTTACCTCAGCATCTCGAGCGAAGCTTCCCACCCATGTTTAGGCCAGACTTTTTGGCCTTGAATCCTCTGGCCGGGTATAGAGGCCTTCAAGAGCTACAGACTGCCACGAGAAACCTGCAAAATCTTGGTGACCCGCTTCGAGGTATGGATGGTTTAAATTTGGGAGATCCTTTGGTCCGTAGCTCGTTGGACTCCTTGAACAATGCCCGGAATCTGGCGAACCTGGCCGAACTGTCGCACGGCCGTGGCCTCGGCGGTCAGGCGCATCCTCCTCCACTCGAGGCCAACCTGGATTTTTACTCGGCGCGCCTAAGGAGCCTCGCTAATCCGTCCTTAGGCGCGGCTCCACCTAGTAGCGGTAATTCGACGACGAATTCGAACCCACCCGCCCCGGTACCGCCTGTACCTGTACCGAGCACCGTCCAGCAGCAGCAGCAGCAGCAACAGCAACAGCCAGCAGCACAAAATCACAGTCAACCTGTCGAACCTCCCAGTCCAGCGTCGAACAACGCTACAATACTGACACATAACAATCACCAAAAGGAGAATTCGCCGCCCTGCTACAGTCAGAGCCCGGTTGGTCATCATAACAACAATAATTCGACTGATAGCGAGAAGACCAGTCCACCTGTCGCCTCGACGCCCATCATCGCAGATTCCGTGTCAGAAACCATTTACTCGTGCGAGGTCTGTGACAAGAAGTTTCGTTTCCAGTCGAATCTCATCGTGCATCGAAGAAGTCACAGGGATAAGGAGAGACAGTATGGACAAGATGGAACGCAGGATGGACAAACGACGCCGACGAGGTGCGAAGTTTGCGAAATGGAGATTCCAAGCTTCGCCGAGTTGAGGAAACACATGAGAAAAGAACACCAGGAGAATCTGAACGCGGCTAGTCCTCAAGGGAGCGTGGAAACCGTTCCGGACGATGGTTCCAGTTGCGATGAGAATATGGATCTCGATGAAGCGGATGAGAACGAACAGAAAGGAGAAAGGGAAGATACCGAGGAGAATACACCAGAGGATCTGAGTACTACTCAAGGCCAAAGCGGAGAAGAAAGCGGCGGTAGAATAGAGCAGAAACCAGCCAGTTTAGTCGGTGATCTGATGGAAAAGTTTGGATTAAGTAACATCGCGCAATACTCGGAGGCTTATAGGCAGGCTCTACAGGAGAACCATCGGGGCGGTTTCATTAAAACGGAATCTCCGTCTAACATGACCAACTCTTTGAACAACAACAAGGAGAAAGACAGCGCGTTATCGCCCACGAACTTCAATTCCTCAACCACACCCAATATATTTTCAGGTCAGGGTTTTCCCAGATCTTCGGGGCCGGACTTCGGTGGCCTCTGGCTACCTAGTCCCCATTATCTAGAAAACAATGAATTCCGTAAAGCAACGAAGGCTACCACGTCCAGTTTAGCTCTTCAAGGTCTACCAAGTCCCTTATTGAAAAAGGAACGAAGTGGTAGGAACGATACATGCGAGTATTGCGGCAAAGTATTCAAGAATTGCTCGAACCTAACGGTACACAGGCGATCTCACACAGGAGAGAAACCATACAAGTGCGAATTGTGCTCGTACGCGTGTGCACAGAGTTCGAAACTGACCAGGCACATGAAGACACACGGTAGACACGGGAAAGACACGTACAAATGTCGCTTCTGCGAGATGCCATTCTCGGTGCCAAGCACGCTGGAGAAGCACATGAGAAAGTGCGTGGTTGTGGTGCAACAAGGTCCAAAATTAGGCATGCCATATCCCGGTAGCCAGGATGAGGACTCTTCGTTGAGTACCAAGGACACTTGA
Protein Sequence: MLQVFNRDRLHYPVSEPRWLQCSQCSRRLSSAWELLQHVQSVHGARLYTSPSSSTNSSSNTPAPSPPTPTPTHTHHLSPPNHLNLSSKSTGSSSTGNSSGGTSSSGNSSGRQQLQSSASLVGDPLHSFLRLPQHLERSFPPMFRPDFLALNPLAGYRGLQELQTATRNLQNLGDPLRGMDGLNLGDPLVRSSLDSLNNARNLANLAELSHGRGLGGQAHPPPLEANLDFYSARLRSLANPSLGAAPPSSGNSTTNSNPPAPVPPVPVPSTVQQQQQQQQQQPAAQNHSQPVEPPSPASNNATILTHNNHQKENSPPCYSQSPVGHHNNNNSTDSEKTSPPVASTPIIADSVSETIYSCEVCDKKFRFQSNLIVHRRSHRDKERQYGQDGTQDGQTTPTRCEVCEMEIPSFAELRKHMRKEHQENLNAASPQGSVETVPDDGSSCDENMDLDEADENEQKGEREDTEENTPEDLSTTQGQSGEESGGRIEQKPASLVGDLMEKFGLSNIAQYSEAYRQALQENHRGGFIKTESPSNMTNSLNNNKEKDSALSPTNFNSSTTPNIFSGQGFPRSSGPDFGGLWLPSPHYLENNEFRKATKATTSSLALQGLPSPLLKKERSGRNDTCEYCGKVFKNCSNLTVHRRSHTGEKPYKCELCSYACAQSSKLTRHMKTHGRHGKDTYKCRFCEMPFSVPSTLEKHMRKCVVVVQQGPKLGMPYPGSQDEDSSLSTKDT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00086621;
90% Identity: iTF_00088302;
80% Identity: -