Basic Information

Insect: Bombus breviceps
Gene Symbol: Trl
Assembly: GCA_014825925.1
Location: CM026187.1:1291300-1320290[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 1.4e-07 1e-05 25.5 2.0 1 23 638 660 638 660 0.98

2 8 1.5e-05 0.0011 19.1 3.0 1 23 666 688 666 688 0.98

3 8 1.7e-06 0.00012 22.1 0.3 2 23 697 718 697 718 0.98

4 8 5.6e-05 0.0041 17.3 0.1 3 23 726 746 724 746 0.97

5 8 1.8e-07 1.3e-05 25.2 3.0 1 23 752 774 752 774 0.98

6 8 3e-06 0.00022 21.3 0.7 1 23 780 802 780 802 0.98

7 8 6.4e-05 0.0047 17.1 7.5 1 23 808 830 808 830 0.98

8 8 2.1e-05 0.0016 18.6 1.1 1 21 836 856 836 857 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	1.4e-07	1e-05	25.5	2.0	1	23	638	660	638	660	0.98
2	8	1.5e-05	0.0011	19.1	3.0	1	23	666	688	666	688	0.98
3	8	1.7e-06	0.00012	22.1	0.3	2	23	697	718	697	718	0.98
4	8	5.6e-05	0.0041	17.3	0.1	3	23	726	746	724	746	0.97
5	8	1.8e-07	1.3e-05	25.2	3.0	1	23	752	774	752	774	0.98
6	8	3e-06	0.00022	21.3	0.7	1	23	780	802	780	802	0.98
7	8	6.4e-05	0.0047	17.1	7.5	1	23	808	830	808	830	0.98
8	8	2.1e-05	0.0016	18.6	1.1	1	21	836	856	836	857	0.94

Sequence Information

Coding Sequence: ATGATGGGAGAGGTGATCAGAGTTTCTGGGAGGGCACCGGATGTCGGGGAATTCCTCAAGGAGGCGATGCTGTCCCAACGGTTCGCCGATGTAGCTCTCTGTTGTACTGGCGGACAAAGATTTTTGGCGCATCGTTTGGTTCTCTCTGCGGCCAGCCCTTATTTGCAGGAAGTGTTGCTGGCGCACAGTAGAACGTCGATGCATTGCGAGCCTATCACAGTGATCCTGGCCGGGGTAGAGGCACCAGAATTGGCGGCGATCCTCGGTTTCGTGTACACAGGAAGCGCGACGGTACCTCGTCCTCGTTTGAATGCGTTTCTGCACGCTGCCGAAGCTCTTCACATTAGACTTCCGCCGGTGCCTGTCGTGATGACCTGCACGCAGGCTGACTGCAAGCAGGAAGACATCAAGGACGTGAAGATCAGTCCAAAGTACCTTCAGTGCGACCGGTATCCGCGCTGTGACCGCTGGTGCCATCCACGTAGGAATCAAGATGGAGATTCCGCGGGCAAGGAGGAATCCTATCCGGCGATCGAGTCCTTGCAAACCGCAAGAGAAATCAGACCGCTTCCTGAATCGATGAACTTTGCCGGATCGAGATATGGACCAAGACCAAGTAGATATTGCTCTACAACGTGGCCCGTTGCTCCTTTCCCGAGCGCGGCTCAAGAAAAGACTATTCACGGTCTAGATCAACGTATGGATAAGGACAAGTTGAATCAGACAGATGTCAGTCGGTATCAACCAATCAGCGTGGTTCCTAGGATCGATAGGATTAGCGACGTAGCCAATGCACACTCGGAAAATCCGTTTGTCGGTTGCGACTCTTCGGAAAAGTCTCGTCAGCAGGAATTTTGCTTTTCCAGGAGCTTGTACGATCTTCGTAGCATGCAATCGAATCCACTGGAGGCGAGAATGAAAGGTGATCACGATCGTTTCCAGGCTACGAACGAAGAAGATATCTCCGGGAGAAATTTATCCCAATACGGTAGCTGTTTCGAGCAAGAGAGGATTCCTGCTGATCGTCTCAGCGTAATTCGTTCTCGAATCGATCCCTGTCAGGGCAAAACCGTGGCTCTACAGTTACCGGCAAGTACCAGATCGTACGAAAATTTGGACGTTGGTGAAGATTTGACTTGTCGTGATCACTGTTTCGTATGGAAATCGCCGAGAAGACAAGTGGCTAATAGAGTCATAGCCTCGCCGTGGAAGCAAACTGTCAGGCCTTACCATTTGCCCAAGTTGCAGCCGATAGTCCTTCAGCCCCACGTCGACGATGCCAAAACCGGGGAAAATCTACGTGTGCCAGAAGTCACGCGATCTCCATCGATCTCTACCAGTCCTAATCGACAGCTCCCCAAAAGTTCCACGCCTGCGGATCATTATTATGGTATCGAAGTTCCTACCACCCACGAAGTTACGTACAATAACGATAAGAAGTTACTGGAAGCGAGCCCTACTTTGGGACCGAGGCCTCAAGAATTATATTCGTCTCAAATTGCATCGTTAACGATCGGTCAAATCGCTCCATCGTTGAATAACGATGGCAGAAACAACGAGACTATCGTGCAATCTCAAAATAACGTAATTTCTACGACAACGAGATCGTTGCCAAGTACCTCGGAGAGTAGTCGTATgaatatcaataaaaagggTAGTTATTTCGGTCAAGCGTTACCTCAGTCGCCGCAGAAGCTGGAAATTTCTCATCCTGTTAGCAGATTGTGCGATACGATCGAGTCGATCGgtaaaatcgatcgtttcgccAACGTGGAAGCCGAGAAGCTGGAGAACGAGACGAGGATCGAGGATAAACTCGCTGAAAGAGTTATTATCAAcagtgataataataataacgatgcTGTAGTTAGTCAGGACGGTGTTCAACGCGGCAAAGGAGCGCAAGAGAATCATAGGTGCGATCAGTGTGGCAAGACTTTCGTTACCAAAGCTTCCCTGAAGGTGCACGTTAGAACGCACTCAGGAGAGAAGCCATTCCGTTGTACCGACTGCGGCAAACAATTCTCCCAACTACGAAATTACAAGTACCACCGAAGCGTTCACGAGGGCACCAGGGAATTCGCAGCCACCTGTCCAGAATGTGGCAAATACTTCAACGACCGCGGCTACCTGAGCTCCCATATGAAGATTCATCGTAACCGTAAGGAGTATGGCTGTGCGGAATGTGGCAAGAGTTTCAATCAACGGGTCGCCTACAACATGCACGTTAGAATCCACACTGGAGTGAAACCGCATCAGTGTGAACAGTGTGGAAAAGCATTTTCCAGGAAGATGTTGTTGAAGCAGCATCTTAGAACCCACTCGGGAGAACGGCCGTATCAGTGTCAGGTCTGCCAGAAAGCCTTCGCTGATAGATCGAACATGACGTTACACACAAGATTACATTCCGGTTTAAAGCCTTATCAATGCACGTTATGCTCGAAGGCGTTCACGAAGAAGCATCACCTAAAGACTCATCTGAATTATCATACAGGAACTAAACCGTATTCCTGTCCAAACTGTGGCTTGAGATTTTCTCAAAGTAGCAACATGAGGACTCATTTCAAGAAGTGTACCGTTAGTAATCCGATAGAAGCAAAGGATTCGCAGATGGAAGGTACTGTGATAGATTCTTCGAAGGTTATACAAGCGAGAATAATATCGAGGACACCTACAGACACGTTAACGCCTCCCAATTCTGACCAGGAATTAAGCATTCTAACGCCGATTTCGAAAAACAACGGAATAGAAGCGATTGGTACGTAG
Protein Sequence: MMGEVIRVSGRAPDVGEFLKEAMLSQRFADVALCCTGGQRFLAHRLVLSAASPYLQEVLLAHSRTSMHCEPITVILAGVEAPELAAILGFVYTGSATVPRPRLNAFLHAAEALHIRLPPVPVVMTCTQADCKQEDIKDVKISPKYLQCDRYPRCDRWCHPRRNQDGDSAGKEESYPAIESLQTAREIRPLPESMNFAGSRYGPRPSRYCSTTWPVAPFPSAAQEKTIHGLDQRMDKDKLNQTDVSRYQPISVVPRIDRISDVANAHSENPFVGCDSSEKSRQQEFCFSRSLYDLRSMQSNPLEARMKGDHDRFQATNEEDISGRNLSQYGSCFEQERIPADRLSVIRSRIDPCQGKTVALQLPASTRSYENLDVGEDLTCRDHCFVWKSPRRQVANRVIASPWKQTVRPYHLPKLQPIVLQPHVDDAKTGENLRVPEVTRSPSISTSPNRQLPKSSTPADHYYGIEVPTTHEVTYNNDKKLLEASPTLGPRPQELYSSQIASLTIGQIAPSLNNDGRNNETIVQSQNNVISTTTRSLPSTSESSRMNINKKGSYFGQALPQSPQKLEISHPVSRLCDTIESIGKIDRFANVEAEKLENETRIEDKLAERVIINSDNNNNDAVVSQDGVQRGKGAQENHRCDQCGKTFVTKASLKVHVRTHSGEKPFRCTDCGKQFSQLRNYKYHRSVHEGTREFAATCPECGKYFNDRGYLSSHMKIHRNRKEYGCAECGKSFNQRVAYNMHVRIHTGVKPHQCEQCGKAFSRKMLLKQHLRTHSGERPYQCQVCQKAFADRSNMTLHTRLHSGLKPYQCTLCSKAFTKKHHLKTHLNYHTGTKPYSCPNCGLRFSQSSNMRTHFKKCTVSNPIEAKDSQMEGTVIDSSKVIQARIISRTPTDTLTPPNSDQELSILTPISKNNGIEAIGT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00230793;
90% Identity: iTF_00230793;
80% Identity: iTF_00215137;