Basic Information

Gene Symbol
-
Assembly
GCA_027564075.1
Location
JANSTU010000001.1:103515-104819[-]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 7 3.3e-05 0.002 18.6 4.0 1 23 139 162 139 162 0.97
2 7 2.6e-05 0.0016 18.9 2.1 1 23 168 190 168 190 0.99
3 7 0.00011 0.0068 16.9 0.6 1 23 196 220 196 220 0.98
4 7 0.24 15 6.5 0.3 3 23 228 250 226 250 0.91
5 7 3.7e-07 2.2e-05 24.8 0.4 1 23 256 280 256 280 0.98
6 7 3.7e-05 0.0022 18.5 2.3 1 23 286 308 286 308 0.97
7 7 0.00042 0.026 15.1 0.9 2 23 315 337 314 337 0.94

Sequence Information

Coding Sequence
ATGTTCACGCTGCTATCACCCTCTACTTCAGCTACTGGATCACCGCTTGACATTGATCCACAACGATACATATCAATCACTTCCTTGCCAAAAGACGGTGAAATATTTGTTGTCTGTGATCCCGTATCCGAACAAAATTCTGTAGAATTTCTTGAGCCGGAGGATGAGACCCTAGGCACAAAAGTATTTGAATATTTCATTGAAAATGGATCTACCAGTACAACGTGTGAGCGAGGTGTATACCACCCTGTGCAGTTAGAAGATGGTACACAATTGGTTTGCCAATTGGTCGACACGGATGACATGATCATTGAAGAGACATGTAGCGATATAGTTAATCTCGACGAAGAAGATAATTATAGTTTATGTGATGTTCCATCTAATTCTAAACTGAAAACTAATAAAAAGCAGATTTATTCATGTGATGAATGTGATAAGGTTTTTAAATCGTCATCATCACGCAGAAGTCATCACCAGCGTACTCATCTCGGTATAAAACCATACTCTTGCGAAGAATGTGGCAATTGTTTTAATACTGGATACGCTCTTAAGATGCACACAAGAACCCACACTAACGAACGACCTTTTAAATGTACCTGGGATGATTGTGAATCAAGCTTCAAGACGTCCGGTGATCTGGGAAGACATTCAAGAACACACACTGGGGAGCGTCCCTTTCTCTGTTCATTCCCGGAATGCGGAAGCGCCTTCGCAACACAATCGATTCGCAAAAAGCACGAGATGACACACACGGGTCAGCGGCCGTACGTTTGTAGTTTTGATGATTGTGGAAAGACATTTAGAAGTTCCACGAACTTGGCAAACCACGAACGCATCCACAGCAAAGAGAAACCGTATTTCTGCACACTGTGCGATCGAACGTTCACCGAGTACTCGTCCCTGTACAAGCATACTCAGGTGCATCTTCCATCACGCTCAATATCGTGCCCAGTGTGTGAGAAGCAATACAAAACGACAAAGGCTCTTGTCAGGCACATTCACCAAAACCATCCTCAAATGCTTGAGTCAACTTTGTTAAATGACGAAGAAGATGAGGATGGCAATCATATATCCGTAACACAACCAGAATCCATACTCCCTGACATTGAATCAACGTTTTCTGCTGATACAACAAATGTTCCACTGTTTTACATTGAAAACGATGAATTAAATAGCGATTAG
Protein Sequence
MFTLLSPSTSATGSPLDIDPQRYISITSLPKDGEIFVVCDPVSEQNSVEFLEPEDETLGTKVFEYFIENGSTSTTCERGVYHPVQLEDGTQLVCQLVDTDDMIIEETCSDIVNLDEEDNYSLCDVPSNSKLKTNKKQIYSCDECDKVFKSSSSRRSHHQRTHLGIKPYSCEECGNCFNTGYALKMHTRTHTNERPFKCTWDDCESSFKTSGDLGRHSRTHTGERPFLCSFPECGSAFATQSIRKKHEMTHTGQRPYVCSFDDCGKTFRSSTNLANHERIHSKEKPYFCTLCDRTFTEYSSLYKHTQVHLPSRSISCPVCEKQYKTTKALVRHIHQNHPQMLESTLLNDEEDEDGNHISVTQPESILPDIESTFSADTTNVPLFYIENDELNSD

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
-
90% Identity
-
80% Identity
-