Bger017724.1
Basic Information
- Insect
- Blattella germanica
- Gene Symbol
- lola
- Assembly
- GCA_003018175.1
- Location
- PYGN01004483.1:2326-86811[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 15 0.026 1.5 10.1 1.5 2 21 114 133 113 134 0.94 2 15 0.0015 0.084 14.0 4.9 2 23 143 165 142 165 0.96 3 15 4.9e-05 0.0028 18.6 1.8 1 22 307 328 307 328 0.97 4 15 0.00085 0.049 14.7 0.8 1 22 398 419 398 419 0.95 5 15 3.6 2.1e+02 3.3 0.0 5 23 437 456 436 456 0.91 6 15 0.0048 0.28 12.4 0.7 1 22 473 494 473 494 0.94 7 15 0.00016 0.0092 17.0 0.6 1 21 520 540 520 541 0.95 8 15 0.01 0.59 11.3 0.8 1 21 605 625 605 626 0.96 9 15 0.13 7.3 7.9 0.6 1 17 634 650 634 651 0.93 10 15 5.9e-05 0.0034 18.4 1.1 1 21 698 718 698 719 0.96 11 15 1.3 76 4.7 2.3 1 13 754 766 754 767 0.92 12 15 9.3e-05 0.0054 17.7 0.4 1 21 853 873 853 874 0.95 13 15 0.0012 0.068 14.3 0.5 1 21 941 961 941 962 0.94 14 15 2.1e-05 0.0012 19.8 0.2 1 21 1022 1042 1022 1043 0.95 15 15 0.0015 0.084 14.0 5.5 1 23 1051 1074 1051 1074 0.98
Sequence Information
- Coding Sequence
- ATGTGTGGAGGTGTATGGACTGTGGGATCAAGCCATTCTTCAAAATCCCCATCGTTGTGTTTGGAATCTGTTGTTACATCCACAAAAATTTCAGTACTGCCTCCTTCATACAGAGTGACCGGCTCCATCCTGAACAACTGTATGCCGTCGTCCAGAAGCTCTACTATAAGGTTTGATagaaataaaatgtcaaattattCATCTACTTACTCGTCTTCCACTAAGAGTAATGCCACAGTTGATCTTGAATCGTTAATGCCTAATttggattttaataatttatctttATCTGCCCAACTATATGCAGATAATACTCCTGCTTTAACTGCAGGACTGCTTAATTGTGAACAGTGTGGACGTACATATACATGCGAGTACACTCTTAGGAGACATTTGAGACTTGAATGTGGTAAAGAAGCCACACTCCAGTGCCCAGTATGTTCCAgacgaacaaaacataaacataGTCTAGTCAGACATATAAACAAATTTCATCCAGGAGCAGATGAAGTTTGGACCATCCCTGACTGGTCAGCTGACTCTTTTCAAGTAAACGAAGCTTCACGATGTGAAGAAGACATTATACCTTCATCTGTTGATGCAATAAACACTAATAATTTGCAAACAATAAATGAACGTTTTGTATGTTGTAATTGTGGAGCATCGTATAATATTAATATGGAACATTTATTTGATCAAATTCCATTGAAGAAATCTTCTACTGATATCGTTGAAATACCTGGGCAATCGTCAACACATTGGCAATTCCAAACCAGAGGAAATAGAAATATCATGAATACAAGTGAAAATCTAGAGACAGACGAATTAGAACTTTTAGAAAACTGGAATGCAGTAGATGTAACGCAGACTTTTTCAGCAGATAATATAGATACCAGAAATGTGAATCAGCATAatgtatataaatgtaaattttgtaacAAAAGCTATTCAGATAGAGCAAAGCTTTCTGCACATCAGCGTAAAGATTGTAGCATTGGACCTAGATATGATTGTCCTTATTGCATTGCTTCTATTAGAAGAAAAGGTATTGGCTCAGCTGATATATGGATACTGAACAGTGAAGATATGAATTGTAATGAAAATGCATGGACAACTGACAACTTATTGTACCAAAATGAAGTTCACAATTATAATTTGTCACATAACAGATCTTTACAGAATCCAAAGGAATTTCCTTGTAATGATTGTGGACGTTCATATCGATGGTCCTATCATTTAATGGCACATAAGCGAAGAGAGTGTGGTCTTAATTCAGCTGACATATGGTTGATAAACAGTGAAGATAATATTTGTGATAAAGAAACATGGACAGCTGAAAATTTATTATGGCACCAAAATGaagttcataattttaatttctcgGATTGCAGAGGATATTCACAGAAGTCAAAAGAATTTTCATGTAACGATTGTGGACGTTCATATAGTTGGCTTAAACATTTAGTGGCACACAAACGAAGAGAATGTGaaatgtattttgaCAGCTTCAATTTAAACATCACTGGAGCATGGACTCTCAAAGATCTAGCTGCAGGATTTGTCTGCGAGagatgtggaaaattatataaacGCAAGAGTTCCCTTCGTAACCATGAACGCGATGAATGTGGCAGAGAGCCTCGAAAACATGGAGAAGTAAAGATTGAATCATGGAGATCTCCATGGAGGTGGGTGAATTGTGTTTTGGATGGAAAAGCTACACAAAAACCTGAAACTGATGCTGATTCTTTGACGACTTTAAGGAGACCCGGACAAATCCCAGTGTCTTGGTTTTCAAAtgcgaataataattataaatgtgaaAGTTGTGGAAAGAATTATAAATGGAAAGGTTCTTTGCGGAACCACAAGAGATTAGAGTGTGGCAAGGAACCTCAATTTCAATGCCATATTTGTCCACATAGAACATACCAGAAAGGAAATCTTCACCAAAAGATAGAAGTTACAGCTTTGGAACATCTCTTCAAATTTGAAGAATCTGGAATTTGGAGTCAGTGTGTTTATGCTAATAATGATAGCACCTACAGAGAGAGTGAGATGAACCATGGACGAATTCAAGGTGTTAAAAAGTATAAGTGCAATGAGTGTGGTAAAAGTTACTCACGAGAGCATAGGTTGCTTAATCATTTGAAGTGGGAATGTGAATCTGGGAAATGGAATCAGAATCTGTTGAACAGTGGTTGTTCTAATGTAACACAAGGGGAAATAAACCCAGCAAGATATAAACTTAATAAaccatttaaatgtaaaaattgttataaaacatattcTCAATCAGTGGTAAACGTTGGAACACTGGCGAATCTACTAAATTTTCAAGAAACTGGAAACTGGGATCAGAATGTTTTTATGAACAATGATAATTCTTATGTAACACAGATGGTAGATGTTGCAACACTGGCGAATCAACTCCATTTTCAAGAAACTGGAAAGTGGAATCAGAATGTTTTTATGAACAATGATAATAATTCTTATGTAACACAGAGTGAAATAAATTTCATACAAAACCCAGGGCGACCTCAACCTTGCAGAAAACAcaaatgtgaaaaatgtggtaAAATGTATGCTCGTAAAGAAGGTTTAAATACTCATGTGAAATGGGAGTGTGGGAAGGATCCTCAATTTTCTtgtcagtattgtttatttaaaacTCATCTGGTTGATGTTAAAGCTTTGGAACAACTCTTCGGTTTTGGACAATCGGCAAACTGGAATCAGAATTTTGATCACAGTGCTTTTACCAATGCTGTTCAAGGAGAAATAAATGCAGCGCAAAAACGAAGGATCCGTATTAAGCCTCATAGGTGTGCAAAATGTGGTAGAATGTATTCTCGAAGAGAGGGATTATTTACGCATGTGAAATGGGAATGTGATAGTAGCAGTGATGGGGACACTAAGCGCTGGTCAGGGTGGTCTATGACTCGTGGAGAAGTACTGACTAGTTTAGACTCGCCAGATTTTATTGCTatcaagaaagaaaagaaatcaCCATCATCAAAGAGAAGTAGTCGTAGAAGTACATCAACACGTGCCCGTGGAGTTTTCCCCTGTGATCGCTGTGGACGATCCTATGTGCGCAAAGACTCTCTTCAGCGTCATTTGCAATGGGAGTGTGGTAAAGAACCAACTTTTCAATGTCCATTCTGTCCACAACGTTGCAAACGTAAAGCACATCAGATTCGGCATATTCGCAGGCAACATAGTGATATGATACAGCTTGTTGATCCCAAAGATAATTCAGCAATCATGGAAGTTATTCATGACTAG
- Protein Sequence
- MCGGVWTVGSSHSSKSPSLCLESVVTSTKISVLPPSYRVTGSILNNCMPSSRSSTIRFDRNKMSNYSSTYSSSTKSNATVDLESLMPNLDFNNLSLSAQLYADNTPALTAGLLNCEQCGRTYTCEYTLRRHLRLECGKEATLQCPVCSRRTKHKHSLVRHINKFHPGADEVWTIPDWSADSFQVNEASRCEEDIIPSSVDAINTNNLQTINERFVCCNCGASYNINMEHLFDQIPLKKSSTDIVEIPGQSSTHWQFQTRGNRNIMNTSENLETDELELLENWNAVDVTQTFSADNIDTRNVNQHNVYKCKFCNKSYSDRAKLSAHQRKDCSIGPRYDCPYCIASIRRKGIGSADIWILNSEDMNCNENAWTTDNLLYQNEVHNYNLSHNRSLQNPKEFPCNDCGRSYRWSYHLMAHKRRECGLNSADIWLINSEDNICDKETWTAENLLWHQNEVHNFNFSDCRGYSQKSKEFSCNDCGRSYSWLKHLVAHKRRECEMYFDSFNLNITGAWTLKDLAAGFVCERCGKLYKRKSSLRNHERDECGREPRKHGEVKIESWRSPWRWVNCVLDGKATQKPETDADSLTTLRRPGQIPVSWFSNANNNYKCESCGKNYKWKGSLRNHKRLECGKEPQFQCHICPHRTYQKGNLHQKIEVTALEHLFKFEESGIWSQCVYANNDSTYRESEMNHGRIQGVKKYKCNECGKSYSREHRLLNHLKWECESGKWNQNLLNSGCSNVTQGEINPARYKLNKPFKCKNCYKTYSQSVVNVGTLANLLNFQETGNWDQNVFMNNDNSYVTQMVDVATLANQLHFQETGKWNQNVFMNNDNNSYVTQSEINFIQNPGRPQPCRKHKCEKCGKMYARKEGLNTHVKWECGKDPQFSCQYCLFKTHLVDVKALEQLFGFGQSANWNQNFDHSAFTNAVQGEINAAQKRRIRIKPHRCAKCGRMYSRREGLFTHVKWECDSSSDGDTKRWSGWSMTRGEVLTSLDSPDFIAIKKEKKSPSSKRSSRRSTSTRARGVFPCDRCGRSYVRKDSLQRHLQWECGKEPTFQCPFCPQRCKRKAHQIRHIRRQHSDMIQLVDPKDNSAIMEVIHD
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -