Bger012590.1
Basic Information
- Insect
- Blattella germanica
- Gene Symbol
- lola
- Assembly
- GCA_003018175.1
- Location
- PYGN01001770.1:15576-98771[+]
Transcription Factor Domain
- TF Family
- zf-C2H2
- Domain
- zf-C2H2 domain
- PFAM
- PF00096
- TF Group
- Zinc-Coordinating Group
- Description
- The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
- Hmmscan Out
-
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc 1 23 0.00047 0.027 15.5 1.4 1 21 82 102 82 103 0.96 2 23 8.3 4.8e+02 2.2 3.6 1 13 111 123 111 124 0.93 3 23 0.75 43 5.5 1.6 1 20 166 185 166 187 0.93 4 23 0.074 4.3 8.6 0.1 3 21 242 260 240 261 0.94 5 23 0.0011 0.065 14.3 3.2 1 23 269 292 269 292 0.94 6 23 0.24 14 7.0 0.3 1 12 359 370 359 376 0.81 7 23 0.48 28 6.1 0.9 1 21 440 460 440 461 0.93 8 23 0.00077 0.045 14.9 1.8 1 23 469 492 469 492 0.97 9 23 0.079 4.6 8.5 0.8 1 21 578 598 578 599 0.91 10 23 4.9 2.8e+02 2.9 0.3 1 11 607 617 607 624 0.75 11 23 0.015 0.86 10.8 0.8 1 21 667 687 667 688 0.95 12 23 0.1 5.8 8.2 0.5 1 21 746 766 746 767 0.87 13 23 0.0022 0.12 13.4 3.6 1 23 775 798 775 798 0.97 14 23 0.27 16 6.9 0.8 1 21 863 883 863 884 0.96 15 23 0.0055 0.32 12.2 1.5 1 23 892 915 892 915 0.97 16 23 0.014 0.82 10.9 0.9 1 21 976 996 976 997 0.95 17 23 3.4e-05 0.002 19.1 0.2 1 23 1005 1028 1005 1028 0.98 18 23 0.038 2.2 9.5 0.9 1 21 1103 1123 1103 1124 0.92 19 23 0.00014 0.0083 17.2 1.1 1 21 1132 1152 1132 1153 0.96 20 23 0.021 1.2 10.3 0.4 1 21 1290 1310 1290 1311 0.96 21 23 0.0016 0.095 13.8 1.3 2 20 1320 1338 1319 1340 0.93 22 23 0.00032 0.018 16.1 3.4 1 21 1427 1447 1427 1448 0.95 23 23 1.2e-05 0.00071 20.5 2.7 1 23 1456 1478 1456 1479 0.96
Sequence Information
- Coding Sequence
- ATGCATGAATTATTCCCATGGGGAAGTTATGATGATCCTGTACCATCTTTGCAAGAAGATAAGTTTTCAAAAAATGGTTCTTGTTCTTTGCAGACTTCTGAAATTCCTAGTTCAATACAATTAATTGAAGATCAGTTTGGTAGTaccaattattataataatggtaATCATTTCCAGTCTCAAAGTACGTTTAGCTCACCTGGTGATAAGAGAACTGTTCATGAATGTGCAGAAGTGCCATGTTATAGTTGTCCTAACTGTTTTAAGAAGTATGcaacaaaatatacattattgaGGCATATTAAGTTTGAATGTGGTAAGGAACCACAATTCCAGTGTATGCAATGTTTCAAACGTTTCAAACATAAAAAAATTACTTATGAAAATGGTTGGTTTCCATCTGATGGGCAGGATTTAGAAATTTATGAGCGGAATCAAAGAGTGGGGGCATTTCGTACATCACTTTCACAATCACATTGTGAAACTAGTGGAGCTTATAAGTGCTTAAAGTGTAGCCGAACTTACAGCTGGAAAAAATCCTTGGTACTCCATCTGCACTCATCTTGGGAGAGTTATTATTCAGATAGGCAATTTTTTCCGGGTTCAAGTTTTCACACTGATCCCatagtaataataaatgaagACGTTCAGGACACCAACAGCACAATGAAGTCGTCAAGcactaaaaattcaaataaatgggTTTCAGACAATGGGTTTGGATGTCCTGCTTGTGGTAAAGTGTATCGTTGGAAAAACAACTTATACAGGCATTTGAAATTGGAATGTGGGAAGGAACCTCAATTTCATTGTCCTTATTGTCCACACCGTGCAAAACGCAAGGGAAACCTTCAGAAACATATAGAATTGAAGCACCTACGTATAAAAGAAACCAATGTCCAGCAACAAGCTATCTTCTCAGAAGAAAATCAAAAGAaacatttattgaaaattgaagaCCATCAAGACACTGGTATGGTTTTATTTCATCAAAGCTCTTACCAAGGAGGAAGTTCATATACACCTTCACCAACAAAAATGGATGGCTCAGGAAATAATTTAGCACAAGATGGTCACAGGTGTACCCAATGTGGTAAATCGTACAGATGGAAAAAGCAGCTTAGTTGGAGTGGACAAGATTCTTCAAGGGTTTTAAATCCTGAATTTTTGGAAAGATTATTTGAGTCTACTTCAAGTTTTAACCAACAACTCCCAGATTTTGCTGGTGGAGGAAAATCTGATCTACAGCAAAGCCATTTACAGTCTGCAAGAGGTCTAGCCAAGATCATATCAGAAGATCAACAGTCTGAAAATGGGTTCAAATgtagaaattgtggaaaactgtATCGATGGAAAAATTCTCTTTATACTCATGTTCGATTAGAATGTGGTAAAGAACCTCAGTTCCAATGTCCTTACTGTCCACATCGAGCGAAACTCAAAGGGaatttgcaaaaacatataaagttaaaacattttcaagattatATTTTTACTATCTTCATTAATTTCCTTTCAGACTTGGATTTTTGGACTAATCAACATCATTCAAGAAAGTATAGTGTAGGAAGGTTCACTAATTTTGAGACACTAGAACCTGCTTTCCAAAATACAAGATTTAATCAACAGAGAGAACTGCAACATCAATCAACTGTATGTGCTTCACAGCCAATAATGATGGACCAACGTTTCTATGATACGACTGCAAATTCACGATTTTCTAATGAAGGATTTCTATGCACTAACTGTGGTAAAACTTATCGATGGAAGAAATCCTTATACAATCATGTTAAACTGGAATGTGGCAAAGAACCACAATTTCAGTGTCCATATTGCCCACATCGAGCCAAACTGAGACAATATTTGCAATCAAGTTTTACAGAAGAAATGGACTTGGGAACGTGTTATACATATGGAAGTTATATTCAACCTCAAGAAGAGAGATATGCATTTACCTCTATCAAGGAAAACAAGAAAACATTTAGTTCAAACAAAGAATTTCAGTGTGGAAAATGCGGGAAAAATTATCGTTGGAAAGAATCTCTTTATAACCATCAAAAATTGATGTGTGAGATATTACTATGGTCTCATCATCTACTAGCAAAGCCCAGTGAAGCATTGGATACTATTTTGCTTGAAGAAGGATCTGAACCCCTTCAATTTAATAAAGATATCGACTATCAAGGAGACAAAAAAGGAAGTCGAGTTAGACAGCGAGATGCATCACATAGAgcatttaattgtaaaaattgtggaAAATCATATAGGTGGATAAATTCTCTCTATAAACATTTGCAACTTGAATGTGGGAAAGAACCACAGTTTCATTGCCCATTTTGTCCACATAGAGCAAAACGAAAATGGAATCTCCAAACACATATTAGAGTGAGGCATGCCTCATTGGTAcagtttatTGACGAAGTTAGAAATATGACTTCATTTCTGTATGGAACAATAGTTGATACAGTTGGTGAACTTCAGCAACATCATGTTCAGGGCACCCCTACTTGCCCCAGTAATTCAGAGATACAAATGTATAATTATTGTTCAGTTAGTGGTGATAATGGAACCAATGAGCAGGACTTATTTCCTTGTCCCTCATGTTTAAAAGTATATCGTTGGAAAAAGTCATTGCATCTTCACATGAGATATGAGTGTGGTAAAGAACCACAATTTCATTGCCCATACTGTCCTTATAAGGCAAAGATAAAGGGTAATCTCATTACACACATAAAGAGAAAACATATTTGTGGAAATGATACAAGGGAAAGAGTCCTTAGTAGTTCGTGGAGTAAATCTTTTGGTGCTACAAATTTTCGTGTTTTCAGTATGGAAATGAATAACCAGCGGAATAATCCTAGATCTTCAAATGTTGTGAGCTGTGCACTACAAAACTCAGCCAAATCTAGTCCAACAAGTGAAGAACATCAGTGTAATCGATGTGGAAAGATTTACCGCTGGAAAAAATCATTGAATCTTCATCTACGTGTGGAATGTGGGAAAGATCCACAGTTTCAATGTCCTATATGCCCTTATAAAGCAAAACAGAAAGGCAACTTAAAAAGTCATGTGAGAGTATTGCATAGTGACCAGGTAAAAACACTTAGTGCAAAACTGGAATTACTTTGGGTCAATAAATCTCGCCACTTCTCCACACAGAATCGTCCTTCAGAAGATGATGAAAGAAAGTTCCAGAATATTGGTGATGCAaataatcatgatcagagggagaATATCTCTAAAGAAACTGTAGCAATAAAAAGTTTATGGCAACATCAGCAGAATTGCAAAACATATATTGGAGCCTTTAAATGCCCTAGCTGTGGAAAAACTTATCGTTGGAAACAATCTATGATGTCTCATTATCGCAATGAATGTGGAAAGGATCCTCGGTTCTCTTGTCCCTTGTGTCCTTATAAATGCAAGCAGAAAGGAAATTTGAAGAGCCATATCCGAgggttagTTCGGGACAAATCTGGTCGATTACATCAACCATGGCACCTTTCTTCAGTCCAAAAGTTGCTAGGGAAGAATACCTCAATAGCTGGTAGTTCAGCTTTAACGGGCTCAAAGCTGAAAGAAGCTGCAATGCGGTTATCAAATTGGCAGCTATATGGAGGATTAAGAAAATCTAATATTCGTAGTAATTCTACAGCCTCTGAAGGTAGATCGTCTTCAAGTGTAAAGGTTAGCATCATGAGAGATGCTTCTCTTACTTCATCTAGTTCATTATCTGGCAGTAACCTTCTGTCATCTGGGACATCTGGGTCTCGAAGCAATCTCCTTTTAGGATCTCATCTATCAAGCATTCGACCTGTTTTTCAGTCACAGAAATATACAGCTTCAGATTGGAAAAAACCTGGAGCTTATAGATGCCCTTCCTGTGGTAAACTTTATCGTTGGAAAAAGAACTTGATATCTCATAGAAGATTGGAATGTGGAAAAGAACCCCAGTTACAGTGTCCATATTGTCCACACCGCACTAAACATAAAAGCAGCCTTATTAAACATGTTGATAGaaatgatgATAAAAAACTTGGGATGGAAGAAGAATTAGTGACTGAGTTTGATGATAGTGTATTTACCACAGATGGAAGTGTACTGTTTTGTAAGTTGTATGAAGTTAAAGTAAGTGCAGAAAAACAGTTAGTGGGAACCTGGAGTGACACAAATGAAAATAGCCCTGCTACTATTGTTTGGCAACAACCTGCATTCTTCCAAACTGATATTCCGATAATCACCAGGACTTATAGTACTATGGAGAAACAGACCCGCCCTTATGCATGTTCAACATGTCATAAAACTTACACTCACAAATCAAATCTGGGTCGTCATAAAAGACTAGAATGTGGCAAGGAACCTCAATTCCAATGTCCATATTGCCCTCAACGCACAACACAGAATTCTTCTCTTCGGAAGCATATAGATAGGCACCATACTGTGAAGATGTTAGATGCTTAG
- Protein Sequence
- MHELFPWGSYDDPVPSLQEDKFSKNGSCSLQTSEIPSSIQLIEDQFGSTNYYNNGNHFQSQSTFSSPGDKRTVHECAEVPCYSCPNCFKKYATKYTLLRHIKFECGKEPQFQCMQCFKRFKHKKITYENGWFPSDGQDLEIYERNQRVGAFRTSLSQSHCETSGAYKCLKCSRTYSWKKSLVLHLHSSWESYYSDRQFFPGSSFHTDPIVIINEDVQDTNSTMKSSSTKNSNKWVSDNGFGCPACGKVYRWKNNLYRHLKLECGKEPQFHCPYCPHRAKRKGNLQKHIELKHLRIKETNVQQQAIFSEENQKKHLLKIEDHQDTGMVLFHQSSYQGGSSYTPSPTKMDGSGNNLAQDGHRCTQCGKSYRWKKQLSWSGQDSSRVLNPEFLERLFESTSSFNQQLPDFAGGGKSDLQQSHLQSARGLAKIISEDQQSENGFKCRNCGKLYRWKNSLYTHVRLECGKEPQFQCPYCPHRAKLKGNLQKHIKLKHFQDYIFTIFINFLSDLDFWTNQHHSRKYSVGRFTNFETLEPAFQNTRFNQQRELQHQSTVCASQPIMMDQRFYDTTANSRFSNEGFLCTNCGKTYRWKKSLYNHVKLECGKEPQFQCPYCPHRAKLRQYLQSSFTEEMDLGTCYTYGSYIQPQEERYAFTSIKENKKTFSSNKEFQCGKCGKNYRWKESLYNHQKLMCEILLWSHHLLAKPSEALDTILLEEGSEPLQFNKDIDYQGDKKGSRVRQRDASHRAFNCKNCGKSYRWINSLYKHLQLECGKEPQFHCPFCPHRAKRKWNLQTHIRVRHASLVQFIDEVRNMTSFLYGTIVDTVGELQQHHVQGTPTCPSNSEIQMYNYCSVSGDNGTNEQDLFPCPSCLKVYRWKKSLHLHMRYECGKEPQFHCPYCPYKAKIKGNLITHIKRKHICGNDTRERVLSSSWSKSFGATNFRVFSMEMNNQRNNPRSSNVVSCALQNSAKSSPTSEEHQCNRCGKIYRWKKSLNLHLRVECGKDPQFQCPICPYKAKQKGNLKSHVRVLHSDQVKTLSAKLELLWVNKSRHFSTQNRPSEDDERKFQNIGDANNHDQRENISKETVAIKSLWQHQQNCKTYIGAFKCPSCGKTYRWKQSMMSHYRNECGKDPRFSCPLCPYKCKQKGNLKSHIRGLVRDKSGRLHQPWHLSSVQKLLGKNTSIAGSSALTGSKLKEAAMRLSNWQLYGGLRKSNIRSNSTASEGRSSSSVKVSIMRDASLTSSSSLSGSNLLSSGTSGSRSNLLLGSHLSSIRPVFQSQKYTASDWKKPGAYRCPSCGKLYRWKKNLISHRRLECGKEPQLQCPYCPHRTKHKSSLIKHVDRNDDKKLGMEEELVTEFDDSVFTTDGSVLFCKLYEVKVSAEKQLVGTWSDTNENSPATIVWQQPAFFQTDIPIITRTYSTMEKQTRPYACSTCHKTYTHKSNLGRHKRLECGKEPQFQCPYCPQRTTQNSSLRKHIDRHHTVKMLDA
Similar Transcription Factors
Sequence clustering based on sequence similarity using MMseqs2
- 100% Identity
- -
- 90% Identity
- -
- 80% Identity
- -