Basic Information

Insect: Blattella germanica
Gene Symbol: ttk
Assembly: GCA_003018175.1
Location: PYGN01000330.1:1499357-1537941[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 14 0.063 3.7 8.8 3.8 2 23 571 592 570 592 0.94

2 14 9.8e-07 5.7e-05 24.0 0.4 2 23 599 620 598 620 0.98

3 14 0.00024 0.014 16.5 0.1 1 23 626 648 626 648 0.97

4 14 2e-07 1.1e-05 26.1 0.6 1 23 656 678 656 678 0.98

5 14 6e-05 0.0034 18.4 3.8 1 23 684 706 684 706 0.98

6 14 0.00045 0.026 15.6 2.6 2 23 716 736 715 736 0.95

7 14 0.0088 0.5 11.5 4.6 1 23 740 763 740 763 0.89

8 14 2.6e-08 1.5e-06 28.9 1.7 1 23 769 791 769 791 0.99

9 14 7.2e-06 0.00041 21.3 1.2 1 23 803 826 803 826 0.97

10 14 0.00053 0.03 15.4 0.5 1 23 834 856 834 856 0.98

11 14 5.8e-06 0.00033 21.5 1.0 1 23 862 884 862 884 0.96

12 14 0.00021 0.012 16.7 5.6 1 23 890 912 890 912 0.98

13 14 0.1 6 8.1 2.0 2 23 926 947 925 947 0.94

14 14 4.9e-05 0.0028 18.6 2.3 2 23 954 975 953 975 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	14	0.063	3.7	8.8	3.8	2	23	571	592	570	592	0.94
2	14	9.8e-07	5.7e-05	24.0	0.4	2	23	599	620	598	620	0.98
3	14	0.00024	0.014	16.5	0.1	1	23	626	648	626	648	0.97
4	14	2e-07	1.1e-05	26.1	0.6	1	23	656	678	656	678	0.98
5	14	6e-05	0.0034	18.4	3.8	1	23	684	706	684	706	0.98
6	14	0.00045	0.026	15.6	2.6	2	23	716	736	715	736	0.95
7	14	0.0088	0.5	11.5	4.6	1	23	740	763	740	763	0.89
8	14	2.6e-08	1.5e-06	28.9	1.7	1	23	769	791	769	791	0.99
9	14	7.2e-06	0.00041	21.3	1.2	1	23	803	826	803	826	0.97
10	14	0.00053	0.03	15.4	0.5	1	23	834	856	834	856	0.98
11	14	5.8e-06	0.00033	21.5	1.0	1	23	862	884	862	884	0.96
12	14	0.00021	0.012	16.7	5.6	1	23	890	912	890	912	0.98
13	14	0.1	6	8.1	2.0	2	23	926	947	925	947	0.94
14	14	4.9e-05	0.0028	18.6	2.3	2	23	954	975	953	975	0.95

Sequence Information

Coding Sequence: ATGGATCCAAAAAATTTACAATACACCACAGTGCCATTAATTAGTCAAAGTGTAGCTGTCCAGTACCATACCGTCCAATGGGAAGATCATTTTAATCATTTGATATCAACATTGAAAGATTTTACAGTGTTGAATATACAAACAGATATTACATTAGTAACGGGAAATCATAAAGTGCCAATTCATCGAATAATGTTATCGTGCTACAGTTCCTACTTCAAGGAGTGTTTGACAAATGAAATTTTCAACTGTTATTTTGTTATTAGTGATATTAATGAATCCCTATTAAATATccttattaactttatttatacTGGTACAGCTTCAGTTCCTGTTGCAAGTTTAAATGATTGGTACAAAACAACTAAATTACTACATTTAGATTGTATAGCAGACTCTAGAAGGAACCATCCTTCTGAAAGTTTGACATATTTTACATGGCCTCAGTACAGAGAAACTATTCTCCATTATTTTTGGCAGTCTAGAAATGATCCAAGAGATTGTGATGTGATTTTGGTTACTGATAACTTTACACAAACTCTTGCACATTCTTGTATATTAAGTGCATGTAGTAGatatttacttaatatatttCTAAGGCATACACAACTGAACAAGAAAAAGCCGTATGTTTTAATTCTACAGAATGTGAAGAGTGAAGACCTAGAGGCCGTGCTTGAATTTTGTTATAGGGGCTCCATATCAGTGCTTGAAGAAAATATGAACTCTGTATATGATGTAGCTGAGCTACTCGGAATTCAAGATTTGTGTAAAAGACTAAGTTTTGTCAAACCCATGATTGGAAAAATGTCAGAATTACAAGAACCAAAATACACATCAGATGTCATCAGTAGGATCAAGACAGTGCACTGCATATCCCAACAAACAGAACAGTCCATTCAATTACAAAACATATTCCGTAACTTTCTTGAATATGAACACTTGGTAGATATTACTATAGTTAAAGATAAACAGAGCTTTTCTGCTCATATAGTTGTGCTAAGTGCCTTTAGTATGTATTTCAAAAGACTTGCTAAATTCCTTCAACACAATATAAAAGATGCTTTTGTACTTGTTAAAGACTTGAGAACTCAGCATATTAGAGCATTTTTAGATTATATGTATAAAGGAGAGGCAGAATTTCCAGGGACCACAGACGTCATTTGTGATATCATGTCAGAATGGATTGATTTCACATTGTTGTCAATTTCTGAATCAGAAACTTGTCAAATTTTATCAAATGCCACACCTGTTATTAAAGAAAAGACTGAAATTAAAGAATTATTGGAAGATCACAGCAGTTTCAACATATATCATCCTATCAATGGTTTCAGTCAGAATGTACAATGCCAGGAGCAACAACAAGGACAACAGCAAATCACAAACTCAATAGCTGTTACAGATACTTTCCAACAAGATGCCAACATAACTAATCAAGAATCTGAAAGCATGAAACTTAATATAGACTTAGAAACTAAACCCACAactactgaaaatataaaaagcaAGGAAGCATCTCAAGAAAATGTGATTGCAGAAAAAGTGAAGGATGTAATTACAACAGAGGAGTACAGCAATTCAAAAACAGATTTTGATAATAGCTTGGAGGATGATTCCATGGAAAGGAGTACAACACATGAAGCAGATGATGGAGATGGCTCAGATATTGATAGAAGTAATAAGAAATGGAGAGAAAAGACTTCTGTATTGCACTGTTATACATGCAATGAAAATTTTGAATCAAGGAAACATTTTAGAGCACATTTAGTTATCCATCCTAATGGAAGAATAATGAAGTGCAATTATTGTGGTAAAGGTTTTGATAGACCAAGTCAGATGAAACTTCATATCCGTATCCATACTGGTGCAAAACCATTTTCTTGTAAGCAATGCGGTAGTGCATTTGCAGCTAAGAGTGCTCTCAGAAAACATATTGATATTCACGCTAAGAACAAAGGCAAAATGTTTGAATGTGCTGTATGTAATAAATCATtttcaagaaaggaatatttaGAGGAACATATCAGGACTCATACAGGTGCAAAGCCATTTGAATGTCCcatatgccataaaacatttGTTGGTCGCACTGGACTGAATCATCACAAAAAGACTCATATAGATGCTGAAGAAAAGAAAGATTGTGTCTGTGAAATTTGTGGTAAGAGTTTCACTCGACATGCTCTTTGGACCCATGTGAAGTCTCATGAGAAAACTCATCGCTGTCATTATTGTGCCAAATGTTTCTCCACTGCTTCTGCTCTTAGATTTCACATTGCAGGAACACACCTTGGATGTAGAAGCTATCAGTGTGAAGTCTGTGGCAAAAGCTTTATTCAAAAGAATCATCTCATTCGTCATATGAAGGTTCATGAAATTACAAAAGAAGAGAAAAGTACAAAACCATATTCTTGTAGTAAGTGTCcaaaaatatttaagacagaGACTAAGCTTCAATCTCACATGAAAGTAGAACATTTAGTGGCTGGGGAACGTCCATATTcatgtgaaatatgcaataagCGGTTTGCAGGTCGCAGCACAGTAATCTATCATCGCCGTGCCCATACTGGCGAGAGACCTCATGCCTGCTCTACTTGTGGTAAAACATTTATGCGTCCTGATGCTTTACAGCAACATATGACTTCTCATACTGGTGAACGTCGTCACCAGTGCTCGGTATGCAACAGAAAATTTGCTTCCAAACATACTCTCAATAAACATGTCCAATCTCATAAGGAAACCACCGAGAACACTGAAAAACAAGGAACGTCCACTTGTGAAGTTTGCCATAAGGACTTTCCTTCTGAGGCTCAATTTTCTTTACATTCTCATATTCATAATGGCTGTAAACCTTTAAGATGTTATGTATGTCATAAATCATTCCGATACCAAGATAGTCTCACAAAACACCTCGGTATTCATAATACCAGCACACATGTTGGTCAGGAAGAGAGCCATAGTAATGTGTTGTCTTGCATGTATGCATATGTATGTAGTCAGCCATTTGAACCAGCTCCAGAGCTTGAACGTGCTAAGGAGAATGAACAACACACTTTTGGAACCGAGAACATTGtgcataataatgaaaaaatctTGATATCAGACTCACTCCAACAATATAACATGCCTTCTGCAATTATCACTACTAATGTTTGTGttacaaatgaaaacaaaactaaCTTAGGAATTCCTACAAGACGACCATATAGTATCACCATTGATGGCAATTTATGCTGCAACCCTGAATCTCAATCTCAAAGTACTAGTACTAACATTATGACTGACaatgtgaatataaatttacCACCACCACCTATACCACCTACATTTCATCATCAAAATCTAGATATTCATCCAATAGTGAGCTTGGCAGCTTCACATACACATGACCAACAAACTCATCCTCATATCGAAATGATTGGGAACCCTTCAATAGGCCCCACACCTGTACCATATGCAGAGCAAATACCAAAACCATTTCTTTTCATAGAAAATAACACTCACCTTTCTCAGGATATTGCTAGACAAAAACAAAATAGATAA
Protein Sequence: MDPKNLQYTTVPLISQSVAVQYHTVQWEDHFNHLISTLKDFTVLNIQTDITLVTGNHKVPIHRIMLSCYSSYFKECLTNEIFNCYFVISDINESLLNILINFIYTGTASVPVASLNDWYKTTKLLHLDCIADSRRNHPSESLTYFTWPQYRETILHYFWQSRNDPRDCDVILVTDNFTQTLAHSCILSACSRYLLNIFLRHTQLNKKKPYVLILQNVKSEDLEAVLEFCYRGSISVLEENMNSVYDVAELLGIQDLCKRLSFVKPMIGKMSELQEPKYTSDVISRIKTVHCISQQTEQSIQLQNIFRNFLEYEHLVDITIVKDKQSFSAHIVVLSAFSMYFKRLAKFLQHNIKDAFVLVKDLRTQHIRAFLDYMYKGEAEFPGTTDVICDIMSEWIDFTLLSISESETCQILSNATPVIKEKTEIKELLEDHSSFNIYHPINGFSQNVQCQEQQQGQQQITNSIAVTDTFQQDANITNQESESMKLNIDLETKPTTTENIKSKEASQENVIAEKVKDVITTEEYSNSKTDFDNSLEDDSMERSTTHEADDGDGSDIDRSNKKWREKTSVLHCYTCNENFESRKHFRAHLVIHPNGRIMKCNYCGKGFDRPSQMKLHIRIHTGAKPFSCKQCGSAFAAKSALRKHIDIHAKNKGKMFECAVCNKSFSRKEYLEEHIRTHTGAKPFECPICHKTFVGRTGLNHHKKTHIDAEEKKDCVCEICGKSFTRHALWTHVKSHEKTHRCHYCAKCFSTASALRFHIAGTHLGCRSYQCEVCGKSFIQKNHLIRHMKVHEITKEEKSTKPYSCSKCPKIFKTETKLQSHMKVEHLVAGERPYSCEICNKRFAGRSTVIYHRRAHTGERPHACSTCGKTFMRPDALQQHMTSHTGERRHQCSVCNRKFASKHTLNKHVQSHKETTENTEKQGTSTCEVCHKDFPSEAQFSLHSHIHNGCKPLRCYVCHKSFRYQDSLTKHLGIHNTSTHVGQEESHSNVLSCMYAYVCSQPFEPAPELERAKENEQHTFGTENIVHNNEKILISDSLQQYNMPSAIITTNVCVTNENKTNLGIPTRRPYSITIDGNLCCNPESQSQSTSTNIMTDNVNINLPPPPIPPTFHHQNLDIHPIVSLAASHTHDQQTHPHIEMIGNPSIGPTPVPYAEQIPKPFLFIENNTHLSQDIARQKQNR

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00209892;
90% Identity: iTF_00209892;
80% Identity: iTF_00209892;