Basic Information

Insect: Biston betularia
Gene Symbol: -
Assembly: GCA_905404145.1
Location: FR989892.1:2864386-2880863[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 8 0.0047 0.38 11.9 0.7 1 23 267 289 267 289 0.97

2 8 0.00026 0.021 15.8 6.7 1 23 321 344 321 344 0.96

3 8 0.0043 0.35 12.0 1.0 2 21 349 368 349 369 0.92

4 8 0.00016 0.012 16.6 0.6 1 23 393 415 393 415 0.98

5 8 0.00012 0.0099 16.9 4.3 1 21 424 444 424 449 0.94

6 8 0.00037 0.029 15.4 1.7 1 23 457 480 457 480 0.92

7 8 0.0026 0.21 12.7 0.3 1 23 486 509 486 509 0.96

8 8 0.03 2.4 9.4 0.4 3 19 522 538 520 539 0.89

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	8	0.0047	0.38	11.9	0.7	1	23	267	289	267	289	0.97
2	8	0.00026	0.021	15.8	6.7	1	23	321	344	321	344	0.96
3	8	0.0043	0.35	12.0	1.0	2	21	349	368	349	369	0.92
4	8	0.00016	0.012	16.6	0.6	1	23	393	415	393	415	0.98
5	8	0.00012	0.0099	16.9	4.3	1	21	424	444	424	449	0.94
6	8	0.00037	0.029	15.4	1.7	1	23	457	480	457	480	0.92
7	8	0.0026	0.21	12.7	0.3	1	23	486	509	486	509	0.96
8	8	0.03	2.4	9.4	0.4	3	19	522	538	520	539	0.89

Sequence Information

Coding Sequence: ATGAAGGAAATCAACATAAATATTGAGGGATACAATGTGAATGGAGTATGTGTGGGTTGCTTGAGTTACAATCGCAAAATGTTCTATGACAAAGATGTTAAAGAGTGTCTTAAAAGAATTGGAGATATCGACATTCCAGAAGAACTATCCGTACAAGTATGCTGGGAATGTTTAGCAGCTATAAAGAATGTTAAAAAATTCCAGGACAAGATACTGAAGTCTTATAATGTGCTTATTGAGTATTCACAAAAGCACACATATCTGGATTCACCTGAAGACTTAACCAAACATGGTACCACTGGCCTGGTCACTGTTCAGTTGGACCAGCATGACTTTTCTAATCTATCGGAGAATACAAGCAAAGAGCTTGTGAAGGAAGAGTCTGAGGAAGTGCCTCTTGAATATAATGTAGAATTTGATTCAGTAAAAGACGAACCAGAATTCGAAGACAGCCAGTTCGAAGACTTCGCCGCTGAAGACAGTGATGATCACAAAGTACAGTATGAATCGGACGAGGATGTACAACTCTCCGAGTTAAAAAGGAAAAAAGATAGAAAAGATAAAGGAAAAAAGAGCAAAGACTCAAAACTACCCCGCAAGTTGAAGAACCTGCCGTCCAGTATCGTGGAGCTCCACACGATGACTGAAGCTGAGATGTGGACGGTGAGAGCTCAGGATGTCACCAGCGAAGTGTTTCAAAGGCTCCGATACAAGTGTGCAGATTGCATTATTGGCTTCAACACGGAGAAACTGAGGGATTATCATTTTAATAAGAAACACAAGCAGAAAGGTAACAAGTACCAGTGCGACGTCTGCAAAGCATATTTCTTGAACAAAGATAATTTGACTGTCCATCGTACACTACACATGTCTGCGTACCGATGTGTTCAGTGCACACTAACCACTACACTGAAAAAGAGAATAGTTAGACACGAATGTGCGAAACATGTGTTCGAAGAACACAAGTGTATGGATTGTGATAAATCTTTCAGTTCAAAATCAAAGCTGTCTTATCACAAAAACGTCTGCCATCAAGAGAAGCCACAGTGCGACTGTTGTGGAAAAGTTTTTGCCAACAAAATGACATTGAAATATCATCTCAAAATATATCCACAGAATAAAGATGACAAACCGAAGGAAAAGAAATACATCCCTGTAATCCACGACGGTTTAACCTATCCTTGCCCGATTTGCGGCAAATTGTTCCAATGGAAACGCAACCTGTCGAGGCATACTCGCAATCACAGGGAGCGGGAAGCGGGCACTGCGCACGAATGCCGAGAATGTGGCAAAACTTTTGCCTCTAGGGATTGCTACAACAACCACATGAGACTCAGCAAACGGCACGCGGAACCGGATACTTACGTACACGAATGTAACTATTGTGGCAAGAAATTCCCCACAAAATGGTGTATGGTAGATCATATAGACTGGGACCATTTGAAGCACGTCAAATACCAGTGCAGTGTCTGTTTTAAGCCGTTCAAAACAGCGAAAATAATGGTCGCTCACATGAATAACATTCACGGGGGGAAGAAAAGAGAAGCGGAAGGTGAACATCTGTGCGAAGTCTGCGGGAAATCTTATAAGACGGTGAAACGGCTCAAAGGCCACGTGTGGGCGATGCACACGCAGCGTTCTAATACGAAGAGCTTCAAGTGCAAACTGTGCGCTGCCACTTTCCTCTGGCAGACCTCCATATACAAACACGTCAGAATGATGCACGATAACACCAGAGCGAAGCCAGCGAGATCAGCTCCGGTGAAGAAGCAAGAGTCCTACTCTGAAATGGATATATCTAACCGGATGTACTTCCAGAACGTGGCTTCCGTCACGAGCGCTGCCATGCCACTGTCGCATCCCGTCGCGAATGGACTTTAG
Protein Sequence: MKEININIEGYNVNGVCVGCLSYNRKMFYDKDVKECLKRIGDIDIPEELSVQVCWECLAAIKNVKKFQDKILKSYNVLIEYSQKHTYLDSPEDLTKHGTTGLVTVQLDQHDFSNLSENTSKELVKEESEEVPLEYNVEFDSVKDEPEFEDSQFEDFAAEDSDDHKVQYESDEDVQLSELKRKKDRKDKGKKSKDSKLPRKLKNLPSSIVELHTMTEAEMWTVRAQDVTSEVFQRLRYKCADCIIGFNTEKLRDYHFNKKHKQKGNKYQCDVCKAYFLNKDNLTVHRTLHMSAYRCVQCTLTTTLKKRIVRHECAKHVFEEHKCMDCDKSFSSKSKLSYHKNVCHQEKPQCDCCGKVFANKMTLKYHLKIYPQNKDDKPKEKKYIPVIHDGLTYPCPICGKLFQWKRNLSRHTRNHREREAGTAHECRECGKTFASRDCYNNHMRLSKRHAEPDTYVHECNYCGKKFPTKWCMVDHIDWDHLKHVKYQCSVCFKPFKTAKIMVAHMNNIHGGKKREAEGEHLCEVCGKSYKTVKRLKGHVWAMHTQRSNTKSFKCKLCAATFLWQTSIYKHVRMMHDNTRAKPARSAPVKKQESYSEMDISNRMYFQNVASVTSAAMPLSHPVANGL

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00034168;
90% Identity: iTF_00207355;
80% Identity: -