Basic Information

Insect: Biston betularia
Gene Symbol: -
Assembly: GCA_905404145.1
Location: FR989885.1:5795219-5796370[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 7 0.054 4.3 8.6 1.4 2 22 147 167 146 170 0.88

2 7 0.0024 0.19 12.8 0.7 2 23 175 195 174 195 0.95

3 7 1.5e-05 0.0012 19.7 5.4 1 23 201 223 201 223 0.98

4 7 0.00073 0.058 14.5 1.6 1 23 229 251 229 251 0.99

5 7 4.8e-08 3.9e-06 27.6 0.4 1 23 257 279 257 279 0.98

6 7 0.5 40 5.5 0.5 5 23 288 307 286 307 0.94

7 7 4.5e-06 0.00036 21.4 1.6 1 23 313 336 313 336 0.95

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	7	0.054	4.3	8.6	1.4	2	22	147	167	146	170	0.88
2	7	0.0024	0.19	12.8	0.7	2	23	175	195	174	195	0.95
3	7	1.5e-05	0.0012	19.7	5.4	1	23	201	223	201	223	0.98
4	7	0.00073	0.058	14.5	1.6	1	23	229	251	229	251	0.99
5	7	4.8e-08	3.9e-06	27.6	0.4	1	23	257	279	257	279	0.98
6	7	0.5	40	5.5	0.5	5	23	288	307	286	307	0.94
7	7	4.5e-06	0.00036	21.4	1.6	1	23	313	336	313	336	0.95

Sequence Information

Coding Sequence: ATGGTCAAACCTCTTACGGTTTTAAAGATATTGCACTGCAGAAACTTATCTGCTAAGCCGAAGAACTCTACAAAGCATAACAGACCCATTGGAAGACGAACGTCCCGCAATTCCATGCATAATATATGCAGAGTTTGTTTAAAAAAAGGCACAATACCCATTCATGCAGACAACCCAGATGAAGACTTAGCTGATGACATAAGTACTTTTGGAGGGATAGAAGTGAATATTTTTGACTCTTATCCAAAACACTTGTGTAGTACTTGTCATGCTCTGCTTCAAGGTGCAATATTATTCAAAAAGACAGCTCAGCAATCAGAAAAGCGTCTTAAAACACTCTTAGACTCTGAGCCAGATATGGATGACCACTTTGGCAACTTGGATCAGGACAGTAGTAATGAAACTTCTACCTCGATTGAAGGCCAGAAAACTGTCTTGACATGCACACAGTGTGACATACAATTCAATACATTGCAAGAGTATGACCATCATAGATATACGGAAGACCATGATCACAAGAAAATGTGTCCAGTATGCAGCAAAATGTACTCGCCTACATATTTCAAGAAACATATGGATCTTCATAAAGGTGAAGCTGCATACATTTGTGATGTTTGTGGAAAACATTTTACAATGCAAAATCACTTTACACGTCACCGCTTGACACATTTCTACAGTTTGCCATTCAAATGTTCCTTATGTCCTTACAAAGGACGGTTCACTGAATCCTTGAGAATGCATATGAGATCGCATACAGGAGAGAAACCATATGTATGTGAAGAATGCCCACGACGGTTTATAAACAAAAGTAACTTAAATAAACATGTATTGACACATAAAAAGGAAAGAGACTTCACATGTGAGTGTGGTCGGGGGTATTATACTAAGCGAGAATTTGACATGCATTTCAAAGTTGAACATGCGGGGATAAAGGACCATATTTGCCAGATATGTGGTAAAGCTTTTGGTTATCGGAAACAGTTGACAAAGCATCAGTTAAAAGTTCATAAGAGAGCAAAGTTAAGAAGTGGAAGAATGCCTATTTATTTACAAATTGAGAATATGAAGGAACTGGAAAACAACTTACCTATTACCTAG
Protein Sequence: MVKPLTVLKILHCRNLSAKPKNSTKHNRPIGRRTSRNSMHNICRVCLKKGTIPIHADNPDEDLADDISTFGGIEVNIFDSYPKHLCSTCHALLQGAILFKKTAQQSEKRLKTLLDSEPDMDDHFGNLDQDSSNETSTSIEGQKTVLTCTQCDIQFNTLQEYDHHRYTEDHDHKKMCPVCSKMYSPTYFKKHMDLHKGEAAYICDVCGKHFTMQNHFTRHRLTHFYSLPFKCSLCPYKGRFTESLRMHMRSHTGEKPYVCEECPRRFINKSNLNKHVLTHKKERDFTCECGRGYYTKREFDMHFKVEHAGIKDHICQICGKAFGYRKQLTKHQLKVHKRAKLRSGRMPIYLQIENMKELENNLPIT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00207326;
90% Identity: iTF_00207326;
80% Identity: -