Basic Information

Insect: Biston betularia
Gene Symbol: -
Assembly: GCA_905404145.1
Location: FR989877.1:12461124-12478268[+]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.0073 0.58 11.3 0.8 1 23 295 317 295 317 0.97

2 11 0.0026 0.21 12.7 0.2 2 23 325 346 324 346 0.92

3 11 0.49 39 5.6 0.5 1 23 350 372 350 372 0.97

4 11 0.00041 0.033 15.2 0.5 1 23 377 400 377 400 0.98

5 11 0.001 0.082 14.0 0.4 1 23 404 427 404 427 0.94

6 11 0.0058 0.46 11.6 0.2 2 21 442 461 442 466 0.92

7 11 0.0087 0.7 11.1 0.3 3 23 476 497 476 497 0.96

8 11 2.1e-06 0.00017 22.5 0.8 1 23 550 572 550 572 0.99

9 11 1.2e-07 9.9e-06 26.3 2.2 1 23 578 600 578 600 0.99

10 11 0.2 16 6.8 3.8 1 23 606 628 606 628 0.98

11 11 4.7e-05 0.0038 18.2 0.2 1 23 634 657 634 657 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.0073	0.58	11.3	0.8	1	23	295	317	295	317	0.97
2	11	0.0026	0.21	12.7	0.2	2	23	325	346	324	346	0.92
3	11	0.49	39	5.6	0.5	1	23	350	372	350	372	0.97
4	11	0.00041	0.033	15.2	0.5	1	23	377	400	377	400	0.98
5	11	0.001	0.082	14.0	0.4	1	23	404	427	404	427	0.94
6	11	0.0058	0.46	11.6	0.2	2	21	442	461	442	466	0.92
7	11	0.0087	0.7	11.1	0.3	3	23	476	497	476	497	0.96
8	11	2.1e-06	0.00017	22.5	0.8	1	23	550	572	550	572	0.99
9	11	1.2e-07	9.9e-06	26.3	2.2	1	23	578	600	578	600	0.99
10	11	0.2	16	6.8	3.8	1	23	606	628	606	628	0.98
11	11	4.7e-05	0.0038	18.2	0.2	1	23	634	657	634	657	0.98

Sequence Information

Coding Sequence: ATGGATTTTTTGGTATTTGAAGATGATGAGCACATTAAAGTGTGTAGGGTCTGTCTACTGATGGATGTAAAAATGTACAACCTACAGAGTTATCCATTAGAAACTCACTTTGAAGCTGTTATTGGAATTCCTGTTATAAGTACCCTGGAGCTCCCTCCGTTCCTGTGCTATGAGTGTGCCACATTAGTTCGGAAGTTTTCTATGTTCAAAGAGAGATGTCTCCGAGGTCAGGCCACTCTATATGGAATCTTACAGAACACAGGAAAGTTCACAGAGCAAGATATAAAGCAAGTGGACGGAAAAAGCCTCCACATCGGATCGAGTCTCACCATCTGTGACACCGGTAGCAGAGATATCATTTTCCATTCAAAGGATGAACCTCAGACAATAAAGGAAGAACCTATTGTTTTACATGGTAACGGCCTACAAGTGACCATAGATATAAAAGAAGAAGATGATTTGGACTATTCTGTGCCAGAGCTGAATCAGTCCAGTGACGATGAGCCCCTCGCCGTTCACAAGACTGGCAAGGAGAAGAAGAAGGGGAAAAAAAGAGGCCGGAAGAAGAAGGTGGTCGAAGAAGATCTAAGTGTGGTTGAGAAATTGGAGCTGGATGTTGATTGTGAACAGAAACCCCTAGAGCTGTCAGAGCCTTTAGAAGAGCCTGTTATCAAAGTGCGCAAAAAGGGCCGACCGAAGAAGGTAGCTTCCGTCCCGCCCCCGGCCCCTGCCCCCGTGGCGCGTCGTACTAAAAATACGGGAGGCGTGCCCACTGACGACGTCAACTTGGATGACTACGTGACTATTATTACACTCACGTTGGAAGAGCAGCTAGAAGAGATAACCAAACGCAAAGAGTCGAGCAACTATCTGAACGCAGCATTCCAGTGCGGACTGTGCTACAAAGGATTCATCGATACTAACGCGTGGAAACATCATATCGGAAAACACGACCCGAGCGCAGGGTCGGTGGAGTGCCCGGTGTGCCGTTTCCGGTTCCCGTCGCGGCGCGCGCTGCAGAAGCACGCCGTCAACCACGAGAAGAAGTACGCGTGCAAAGCGTGCGCATACGTCTCCAAAACTACAACTCAAGCAAAGCAGCATCAGCGATGGCACAAGGGAGTGACATACACATGCGAATATTGCGACGAAGTTTCCACTAAATGGACGTCGTACCTGTCGCATGTACGTATCAAGCATCCGTCGGAGCACATCTGCGGCGTGTGCGGGTACTCCTTCGTCAGCCAGCTCGGCCTCACCATGCACAGGACCATGATGCATAAAGACGTGCGTGAAAAATGTGAAGGGGAAATGGAAGGTCCGTATTGTCAGGAGTGCGACGTCAAGTTTGTCTCCACTGAGGCGTACAACCGCCACATGGTCACTTCCGTTAAACATTCCGAGGGAAACAATTTTAGCAAGGGCTGTCGCGTGTGCGGCGGCACGTTTGGGTCGCCAGAAGAGTTGCGGCTGCACCACCGCGCAGAGCACGCGCGCTCGCGCCCCAAGAACTACGGCAAGAAGAACAACCAGGGCAAGTGGCCACACAACTGCGCGCACTGCGGTGAAATGATAGAGAACGCTCGCGAACATTGGACTCATTTCCGTCGCATGCATCCGGATAAGGCGTACCCTATACAGAAGAACTATGTCTGCGATATTTGCGGGAAAAGTTTCCGGGGTAACGCGTTCCTAACGTACCACAAACGCACGCACAGCTCGGAGCGCGCGTACAAATGCTCGACGTGCGGGAAGGCGTTCTACAACCGAACTAACTTGAACATGCATCTCCGGACTCACTCGGCCGCGCGCCCCTATCCCTGCGACGTTTGCTGCAAAGCCTTCAAATGTAAAGGAGCCCTCGACAGGCACTATCGAAGCCACACTGGCGAGAAGCCTTACGAGTGTGAAGTGTGCGGCAAAGCGTTCGGCCAATCAAACAGCCGCAAACTCCACGTCCGAACGGTGCACTTGAAGCAACCCGCGCCTTACTTACACCGAGCTAGGCAGGAGAAGCGGAAACCACCCTCAAAAGAACTCGCAGTTGAACATCCCTTCGTATACTGA
Protein Sequence: MDFLVFEDDEHIKVCRVCLLMDVKMYNLQSYPLETHFEAVIGIPVISTLELPPFLCYECATLVRKFSMFKERCLRGQATLYGILQNTGKFTEQDIKQVDGKSLHIGSSLTICDTGSRDIIFHSKDEPQTIKEEPIVLHGNGLQVTIDIKEEDDLDYSVPELNQSSDDEPLAVHKTGKEKKKGKKRGRKKKVVEEDLSVVEKLELDVDCEQKPLELSEPLEEPVIKVRKKGRPKKVASVPPPAPAPVARRTKNTGGVPTDDVNLDDYVTIITLTLEEQLEEITKRKESSNYLNAAFQCGLCYKGFIDTNAWKHHIGKHDPSAGSVECPVCRFRFPSRRALQKHAVNHEKKYACKACAYVSKTTTQAKQHQRWHKGVTYTCEYCDEVSTKWTSYLSHVRIKHPSEHICGVCGYSFVSQLGLTMHRTMMHKDVREKCEGEMEGPYCQECDVKFVSTEAYNRHMVTSVKHSEGNNFSKGCRVCGGTFGSPEELRLHHRAEHARSRPKNYGKKNNQGKWPHNCAHCGEMIENAREHWTHFRRMHPDKAYPIQKNYVCDICGKSFRGNAFLTYHKRTHSSERAYKCSTCGKAFYNRTNLNMHLRTHSAARPYPCDVCCKAFKCKGALDRHYRSHTGEKPYECEVCGKAFGQSNSRKLHVRTVHLKQPAPYLHRARQEKRKPPSKELAVEHPFVY

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00044783;
90% Identity: iTF_00207233;
80% Identity: -