Basic Information

Insect: Biston betularia
Gene Symbol: Zfa
Assembly: GCA_905404145.1
Location: FR989886.1:1650133-1662156[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 11 0.0011 0.089 13.9 1.2 1 23 276 298 276 298 0.99

2 11 1.9 1.5e+02 3.7 3.4 1 21 305 325 305 327 0.93

3 11 0.0019 0.15 13.1 0.5 1 23 331 354 331 354 0.94

4 11 2.1e-05 0.0017 19.3 2.1 1 23 361 384 361 384 0.96

5 11 0.0036 0.29 12.3 0.2 2 23 391 413 390 413 0.94

6 11 0.00028 0.023 15.8 2.2 1 23 426 448 426 448 0.96

7 11 0.00013 0.01 16.8 0.2 1 22 454 475 454 479 0.94

8 11 0.00036 0.029 15.4 1.5 2 23 488 510 487 510 0.95

9 11 9.3e-05 0.0074 17.3 2.5 1 23 516 539 516 539 0.97

10 11 4.1e-06 0.00033 21.5 0.6 1 23 548 570 548 570 0.99

11 11 0.0033 0.26 12.4 0.1 1 23 576 599 576 599 0.94

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	11	0.0011	0.089	13.9	1.2	1	23	276	298	276	298	0.99
2	11	1.9	1.5e+02	3.7	3.4	1	21	305	325	305	327	0.93
3	11	0.0019	0.15	13.1	0.5	1	23	331	354	331	354	0.94
4	11	2.1e-05	0.0017	19.3	2.1	1	23	361	384	361	384	0.96
5	11	0.0036	0.29	12.3	0.2	2	23	391	413	390	413	0.94
6	11	0.00028	0.023	15.8	2.2	1	23	426	448	426	448	0.96
7	11	0.00013	0.01	16.8	0.2	1	22	454	475	454	479	0.94
8	11	0.00036	0.029	15.4	1.5	2	23	488	510	487	510	0.95
9	11	9.3e-05	0.0074	17.3	2.5	1	23	516	539	516	539	0.97
10	11	4.1e-06	0.00033	21.5	0.6	1	23	548	570	548	570	0.99
11	11	0.0033	0.26	12.4	0.1	1	23	576	599	576	599	0.94

Sequence Information

Coding Sequence: ATGGAAGGAAGCTCCAAAACGGCAGAACTTTATTGTTTGGGATGTCTCTGTAGTCCTACAGACTCCAAAATACAGGACTATAAAATACAGTATGCACATTTCTGGGCCATATTTGAGGTTAACTCAATAAGATTATGCTATCTATGCAAGAGGATGGCTCAACATGCCGAGATGTTCATACAAAATGTGCAAAGCAATCAGATATTACTACAAAACTGTCTTGGGGACCTCGCTACTACAATGGAAGAGGCTCGCTGTCAACTGCAGCCTTTAATAACACTCTCCCACTCTCCTTTAAATCCTATTACACTATCTGAAAAAGACGATATAGACTTTAAAGCTAGCGGCAAAGAGTCTGAAATAACTGTACCTGTTATCTGTAATAAGGTTAAAAATAATACGAGTAAAAGAGGCAGCCTGTATGACATTGATAATATGAGAAATGAAGAAGAAACCATAGCAATGCATAAGAAAAATATCAAAATAGAATTGAAGGTTGAAGAATCACTGGATCATTTGGACAAAGAATTCGATGATGAGAATGATGATTTCCAAGATCCTTACATTAAAGAAGAAGACGATTTCCCCTTGCATTTATTGAAAAAGGAAATACAAATAGAAGCCATACAAGTAAAAGGCTTAAAGCCACTCGGGAAGAAGGATAGAATTAAAAGGGAAAGGAAAAAAGTTAAGAAAATGATTAGAAAGACTAAAGAGCTACAGAATAATGAGGAACTAGGAATAAGGAAAATTGTAATAACCAAAGAAGAATGCATGGAAGAGAGGAAGCTGCAAGCACAAGACCGGGTTTACTTGAACTGTGCATACAAGTGTGAAAACTGCTTAAAAGGGTTCAACTATAAAGCAGCTTATGATAACCATTTGAAACGACATAGTGAGGAAATGGGTGCGTTCAAATGTGAAATTTGTAAACTTAGAATGGATTCACAAGACAAGTTACTTAGCCATAAAAAATGCCATACAATACGTTTCCAATGCACAGAGTGCGGGATAATCCGCACCAGCCGATCCACCCTACTGGATCACCACAATGCGATCCACAAGCAGGGAGGGAACCAGTTCGCTTGCCCTTTTTGTCCAAAGACTTTTAAACGTCAGATGTCCCAAAGAAAGCACATAAGATACACTCATCAGAACAAAGAACGAGTTACTTGCGCGTATTGTCAAAAAAGCTACGCGAACAAAGAAGTGATAAAATCCCATATGATGGCACAGCATTCAAAAGAAGTAGCAGCAATAGAACCAGCGAAGAAATATCGTTGTGAAGAATGCGGGATGCTGTTCCGGTCACCAACTCATCTCAGAATGCATAGCTACAAGCATTCACTCAGCCGGGATTACTACTGCGTGGAGTGTGACAAAGCATTCAAATCGGAAGCAGTGTTGAAGCAACATTTGAAAACTGCACAACCTCATATAAACTATTCGGACTTGCCGTTATGTTGCGAGCAGTGCGACAAAAGATTTGCGATAAGAAGAGATCTGGACCGACATATGAACAGCGTACATTTGGAGGTCAAACCGTTTAAATGTGACAAATGTAACAAGGCGTATGTTAGCAACTGGTCGCTCAGAGATCACAAAAGACACGTTCACGAAGGATTTAAGCGACCCCTGCGATACCCCTGCAAGTTCTGCGACAAGATATTTGACCGCAGTTCAATCCTCAAAGCGCATATCCGCACGCACACAGGCGAGCGTCCGTATCAGTGTGACAAATGTCCCGCGCAATTCAGCCAATCAGGAGTCTTGGCGACTCACAACAAACTGATCCACCAGCGACTGACGCGCGACGGGAAACCCAAACAAAACTCAGCGATTAAAGATACTTAA
Protein Sequence: MEGSSKTAELYCLGCLCSPTDSKIQDYKIQYAHFWAIFEVNSIRLCYLCKRMAQHAEMFIQNVQSNQILLQNCLGDLATTMEEARCQLQPLITLSHSPLNPITLSEKDDIDFKASGKESEITVPVICNKVKNNTSKRGSLYDIDNMRNEEETIAMHKKNIKIELKVEESLDHLDKEFDDENDDFQDPYIKEEDDFPLHLLKKEIQIEAIQVKGLKPLGKKDRIKRERKKVKKMIRKTKELQNNEELGIRKIVITKEECMEERKLQAQDRVYLNCAYKCENCLKGFNYKAAYDNHLKRHSEEMGAFKCEICKLRMDSQDKLLSHKKCHTIRFQCTECGIIRTSRSTLLDHHNAIHKQGGNQFACPFCPKTFKRQMSQRKHIRYTHQNKERVTCAYCQKSYANKEVIKSHMMAQHSKEVAAIEPAKKYRCEECGMLFRSPTHLRMHSYKHSLSRDYYCVECDKAFKSEAVLKQHLKTAQPHINYSDLPLCCEQCDKRFAIRRDLDRHMNSVHLEVKPFKCDKCNKAYVSNWSLRDHKRHVHEGFKRPLRYPCKFCDKIFDRSSILKAHIRTHTGERPYQCDKCPAQFSQSGVLATHNKLIHQRLTRDGKPKQNSAIKDT

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00034036;
90% Identity: -
80% Identity: -