Basic Information

Insect: Biston betularia
Gene Symbol: Bcl11b
Assembly: GCA_905404145.1
Location: FR989862.1:5750220-5770027[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 13 6.2 5e+02 2.1 2.2 1 21 160 180 160 181 0.92

2 13 0.024 1.9 9.7 0.5 2 20 195 213 194 216 0.94

3 13 0.00022 0.018 16.1 2.0 1 23 256 278 256 278 0.98

4 13 5.1 4.1e+02 2.4 0.1 3 23 354 375 352 375 0.90

5 13 0.33 26 6.1 0.4 2 20 381 399 380 401 0.89

6 13 0.00048 0.038 15.0 2.1 1 23 409 432 409 432 0.97

7 13 0.0016 0.12 13.4 2.8 1 23 453 475 453 475 0.98

8 13 1.1e-05 0.00085 20.2 3.9 1 23 482 504 482 504 0.98

9 13 4e-07 3.2e-05 24.7 1.7 3 23 518 538 516 538 0.96

10 13 8.3e-06 0.00066 20.6 0.6 1 23 544 566 544 566 0.99

11 13 4.4e-07 3.5e-05 24.6 2.5 2 23 573 594 572 594 0.96

12 13 1.5e-07 1.2e-05 26.1 1.5 1 23 600 622 600 622 0.99

13 13 8.7e-05 0.007 17.4 0.1 1 23 628 650 628 650 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	13	6.2	5e+02	2.1	2.2	1	21	160	180	160	181	0.92
2	13	0.024	1.9	9.7	0.5	2	20	195	213	194	216	0.94
3	13	0.00022	0.018	16.1	2.0	1	23	256	278	256	278	0.98
4	13	5.1	4.1e+02	2.4	0.1	3	23	354	375	352	375	0.90
5	13	0.33	26	6.1	0.4	2	20	381	399	380	401	0.89
6	13	0.00048	0.038	15.0	2.1	1	23	409	432	409	432	0.97
7	13	0.0016	0.12	13.4	2.8	1	23	453	475	453	475	0.98
8	13	1.1e-05	0.00085	20.2	3.9	1	23	482	504	482	504	0.98
9	13	4e-07	3.2e-05	24.7	1.7	3	23	518	538	516	538	0.96
10	13	8.3e-06	0.00066	20.6	0.6	1	23	544	566	544	566	0.99
11	13	4.4e-07	3.5e-05	24.6	2.5	2	23	573	594	572	594	0.96
12	13	1.5e-07	1.2e-05	26.1	1.5	1	23	600	622	600	622	0.99
13	13	8.7e-05	0.007	17.4	0.1	1	23	628	650	628	650	0.98

Sequence Information

Coding Sequence: ATGGCTTCTCACAACGTTGAAATAAAGATCGAGAAACTATGCCGCACTTGCTTATCGAAAGACAACGAGCTGAATTCTCTTTTTGATATCACTGTTGGATCTGTGTCCCTGGACTACGTAGTAACTGCAATTACTGGACTTAAGATCCGCAAAGGAGATGGGCTACCTTCGACAATATGTTGCGAATGTAAAGACAAGGCAGAAAAGGCATATGATTTCAAAAAGAAATCACAAGAAGCTCATATTTCACTTCGAGGTTTATATAAGAAAGAAATGAAAATACTGCAGAAATCGGAAGATATCAGTGTTAAAGAGAGCAAACCAATGGATGTAAAAACTGAACATGTATCATTTGATGACAATGGTGATTTTTCTGATCCTGATTATAGCTTTCCGCTTAGCAATAATCCAGATGAATCTTGTACTACAGAAGTTACTGTGAAACATGAAGCTTGTAAAGAAGAAAATGCATCATTCTTTGAATGCAAAAAATGTTGCCTTGTATTCGAATCTGCTGTTAAATTTCTAGAACACAAGAAAAAAAAATGTGTAAAAGTTGAATTTGAGGATGTGAGTGGCACATACTGTCCAATTTGTGGCACTTGCTATGATGGCGACCAGAGCCTCTCCAAGCACATGTGGGCGCACCATGCTGATTTGATGGGTCCAAAAAAGAGGGGACGGCCTAAAAAGCTCATGACAACGACTATATTGAACAAACTGTCAGAAAATGGTTTACTAATTTCGTCAATGCATGGAAAGACTTATCAGTGTTCTTTCTGTAAGAAGCAAACTAAAACCAAAGAAGATTTATCTGATCACATGATCCAACACAAAGATATGAAAGTGCTATGTTGCATCTTATGTAAGAAAATGTATTTGAAAAAGAAGTATTTTAACTCCCATATGTGCCTTGGCAGAAACTCTTTGATGCCGACTGAAAATGATTCTTCTAACATCCAAGGGGGGAAAAACGGAAAGTCGGCTTTTGCCACTGAAATACAATTGCGGGAGTTATTAGACCCAAACGACGATATGACGTTTACTATGGTTCAAATGTGTTCTGCATGCACCGGCATTTACAACTCGGAAGCCGATCTCATCAATCATCATGACATCGATCACCCAGAACTTTCTCTTAGATGCAATCATTGCTCGAAGTTATTTGCGTCAGTGAAAACAGCGGCGCGTCACAGAACAGTGTGTAAACAAATAGAGAGAATGCATAAATGCACGACTTGTGGCCTCAAGTTCGCCTTCGAAATTTCACTGAACAAACACATACTGAGGTACCACCAAGGGGAGAGCGTCTCTGTCTCCTTCATGAGAAAGCAAAAGACCGACGAAAATGTCCAATATCAGTGCGACACGTGTCATAAAATGTTTCTCAAGAAAGACTCTCTCGCGAAACACGCTAAGTTGCACATGCCAAATCAAAAACTTTACGAATGCGATATCTGCCATAGGAAGTTTAATCGCACGGATAATTTACGAACACACAAGAAGATCCACGACGTGGACCGAGTGAAGCCACCGGCGAATAATTGCTTATGCTTGTACTGCGGTCGAGGCTTCTCAAACTCTTCGAATTTAATCGTGCATATGCGACGTCATACCGGCGAGAAACCTTACAAGTGCGACTTCTGTGCTAAAGGTTTCCCGAGGTCATCAGATCTATTAGTTCACAGAAGATCGCACACTGGCGAGAAACCTTGCGTTTGTCGCATTTGTGGCAAAGCGTTCTCTCGAAGTAACAAGCTGTCACGTCACATGCGTGTTCACACGGGACAAAGGCCGTACAAGTGCACGTACTGCGAGAAAGCATTTTCTCAGAGCAACGACCTCACTCTCCACATACGACGACACACCGGTGACAAGCCCTACGTGTGTGAGTTGTGTGGAGAGAGGTTTATACAGGGAACAGCTTTGCAGAATCATCGGAGGGCTCATGGCCATTTCCCTCTGCCACCGCCCGATCTGGCGTCTCTTACCAGCCAAGTCCAAGCTATCACATACACTGTATCCAATATATCTAATCTCAATCTTCAACAAGAAACTCATATGCCGAACTAG
Protein Sequence: MASHNVEIKIEKLCRTCLSKDNELNSLFDITVGSVSLDYVVTAITGLKIRKGDGLPSTICCECKDKAEKAYDFKKKSQEAHISLRGLYKKEMKILQKSEDISVKESKPMDVKTEHVSFDDNGDFSDPDYSFPLSNNPDESCTTEVTVKHEACKEENASFFECKKCCLVFESAVKFLEHKKKKCVKVEFEDVSGTYCPICGTCYDGDQSLSKHMWAHHADLMGPKKRGRPKKLMTTTILNKLSENGLLISSMHGKTYQCSFCKKQTKTKEDLSDHMIQHKDMKVLCCILCKKMYLKKKYFNSHMCLGRNSLMPTENDSSNIQGGKNGKSAFATEIQLRELLDPNDDMTFTMVQMCSACTGIYNSEADLINHHDIDHPELSLRCNHCSKLFASVKTAARHRTVCKQIERMHKCTTCGLKFAFEISLNKHILRYHQGESVSVSFMRKQKTDENVQYQCDTCHKMFLKKDSLAKHAKLHMPNQKLYECDICHRKFNRTDNLRTHKKIHDVDRVKPPANNCLCLYCGRGFSNSSNLIVHMRRHTGEKPYKCDFCAKGFPRSSDLLVHRRSHTGEKPCVCRICGKAFSRSNKLSRHMRVHTGQRPYKCTYCEKAFSQSNDLTLHIRRHTGDKPYVCELCGERFIQGTALQNHRRAHGHFPLPPPDLASLTSQVQAITYTVSNISNLNLQQETHMPN

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00044719;
90% Identity: iTF_00207196;
80% Identity: -