Basic Information

Insect: Biston betularia
Gene Symbol: ham
Assembly: GCA_905404145.1
Location: FR989878.1:8380238-8404322[-]

Transcription Factor Domain

TF Family: zf-C2H2
Domain: zf-C2H2 domain
PFAM: PF00096
TF Group: Zinc-Coordinating Group
Description: The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out: # of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc

1 9 0.05 4 8.7 0.0 2 23 114 136 114 136 0.92

2 9 0.0093 0.74 11.0 0.6 1 23 143 166 143 166 0.92

3 9 1.6e-08 1.3e-06 29.1 0.1 1 23 172 195 172 195 0.96

4 9 8.2e-07 6.6e-05 23.7 2.4 1 23 201 223 201 223 0.95

5 9 5e-05 0.004 18.1 6.1 1 23 229 251 229 251 0.99

6 9 0.00027 0.022 15.8 0.4 3 21 260 278 258 279 0.95

7 9 1.2e-08 9.5e-07 29.5 0.7 1 23 654 676 654 676 0.98

8 9 4.3e-07 3.4e-05 24.6 1.7 1 23 682 705 682 705 0.97

9 9 4.7e-06 0.00037 21.4 3.3 1 23 711 733 711 733 0.98

#	of	c-Evalue	i-Evalue	score	bias	hmm coord from	hmm coord to	ali coord from	ali coord to	env coord from	env coord to	acc
1	9	0.05	4	8.7	0.0	2	23	114	136	114	136	0.92
2	9	0.0093	0.74	11.0	0.6	1	23	143	166	143	166	0.92
3	9	1.6e-08	1.3e-06	29.1	0.1	1	23	172	195	172	195	0.96
4	9	8.2e-07	6.6e-05	23.7	2.4	1	23	201	223	201	223	0.95
5	9	5e-05	0.004	18.1	6.1	1	23	229	251	229	251	0.99
6	9	0.00027	0.022	15.8	0.4	3	21	260	278	258	279	0.95
7	9	1.2e-08	9.5e-07	29.5	0.7	1	23	654	676	654	676	0.98
8	9	4.3e-07	3.4e-05	24.6	1.7	1	23	682	705	682	705	0.97
9	9	4.7e-06	0.00037	21.4	3.3	1	23	711	733	711	733	0.98

Sequence Information

Coding Sequence: ATGCTTCCTATTTACGTTGTTGGCAAATATGGCGATCGAGGCTGGCTGGATGGTACCAACGAGAAGTCGAACTGGCTGAAGCTGGTCCGGTCCTCCAATTATCCACAGGATGTCAACGTTCAGCATTTGCTGCTGGCTGGTCAGGTTTTTTACAAGGTGATTCGTGAAATTCCATCGGGTCAAGAACTACTTCTCGGACCCAGAACTTCTCTGCCCCTGCAAGACTTCTCTGTTGGACCTCATCGCAAACAGATTTCCTCCTCCATCAACCATCCACCTCCAACCTTCAGGGAAACTCCATCTATTCTTGAAAACGAGGAGCACGAGGATACGCAACCCCGGTGTTCCATCTGTGACGCTTCGTTCGCTAATATTGATGTGCTAGACAACCACCTGATTCAAGCACACGGACAGCCGGCAGCCGTGCACAACTGCGAAGTGTGTCTCCGAGCTTATTCCTCGCGAACTCTATTGCTGCGACATCGTGCGCTCGCGCATACTGACATTAGGAAGTACCCTTGCGAGAACTGTCCTAAGGTATTTACCGATCCTTCCAACCTGCAGCGCCACATCCGCGCGCAGCACGCGGGTGCCCGGAGCCACGCCTGCCCTGAGTGCGGGAAGACCTTCTCCACCTCATCCGGCCTGAAGCAGCATACGCACATCCACTCCAGCGTCAAGCCGTTCCAGTGCAAGGTCTGCTTTAAGGCATACACCCAATTTTCGAATTTGTGCCGTCATAAACGCATGCACGTGGCGTGCCGTGCATTGGTCGACTGCGGCAAATGTGGTCAATCATTTAATACTTACGCTTCCCTAACTAAACACAAGAGATTTTGTGACAACGCTACTGCTGCCAGCGGCTTACGAGGCCAATTGCCACAGGGCCTTCCACAGATTCCATCACTGTCAAACGTGATGAATACTCCAAACAATTCCAACCCATTTTCGATAATGTATAGGGAATCTGCACTGCGTCTCCCTTACAACTTTGCGCACTACCCCGCGGCAGCTTTCCTCCCAGAATTTATGAACCCTTTTTTCAACATGCAAGGAGCTCGGCTCGCATTAGAGCAAGACTTTGCTTTGTCGAATGCTCAATTAGCCAAACAGCAAGAGGGTCGTATGTCTGTTAAAAGTATTGATAGCTCTAACTCCCTTGATGAGCCGAAGAAACACAAGGACTTAGAGTTTGATTCCAACAAGAGTGATACAACAGACAGGGCAACTCCAAAAAGCGTTTTTACTAAGCGGTCACCACCTTCAGCTGAGGAAGCAACTTCCCAACACAGACCGTCACCAATGATGCCATCGCATGTAGGATTTAACTTCACTGCAGAGGCATTAAAAAGGAAATCACCCTATGATTACACTTTGAAATTGAGCCAGAGTGACGTACAAGAACCAAAATCAGTGTCTCCTGCGCTAGCTAAAATGTCAAAGAATGATGGTGAAGAAGACAAAGCATCTGAATATTCAGACGTAGAAGATGAAACTACAAAAGGTCTAGATGATCAGCCTCTGGACTTGACCATGTCGCGTAAACCAAGTGACAAGGAATCTGAAGCCGAAGCTGATGATCGTTATTACCGCAATTCAATCAAATCGTATTCTCCTCCAGAAAGTCCTGTAGAAAGGAGCAAGACCCCTGAAAATGATACTACTGATGTCGATGTAGAAAACGTGGAGCCTAAAAGAGAAGAATCGCCCCCGCAGCTCGTGGCTCCTCCGCTTGCATTCCCAATGCCCGTCCATCCGCAGCACAACAACATTATCGATGCCATGTATCGACCTCGGTTTCCGTCCTTTCACACTACAGACTCAATTTTAAACTCTTCGCATACCCCCTATGTCCCGAGTCCGTTTAATTTTTTATCCCCTCTGCTCGGTACTGATGGCCCGGACAGACAAACGAGCGCATACGCGAAATTTGCCGGGACTGGCAAGCTGCGCGACCGTTACGCATGTAAGTTTTGTGGAAAGGTATTTCCGCGAAGTGCGAACTTAACTCGTCACCTCCGAACCCACACCGGAGAGCAGCCTTACAAATGTAAGTACTGTGAGCGATCTTTTTCGATCTCGTCTAACTTGCAAAGGCACGTAAGGAATATTCACAACAAGGAGAGACCGTTTAGGTGCCCATTGTGCGACAGGTGTTTTGGCCAGCAGACGAACCTCGATCGGCATCTAAAGAAGCATGAGGCGGAGGGTGGCGATTCTCCGAGCTCGGCAGATACCGAGCGAGATGACTCGTACTTTGACGATATTAGGTCGTTCATGGGCAAAGTGACATGCTCTCCGGGGGCGCGCTCTCCCCCCGCGACCTCCCCGCATGCCCCGCACCCACCGCACCGTCCTTCGCTCGCCATCTCTACATAG
Protein Sequence: MLPIYVVGKYGDRGWLDGTNEKSNWLKLVRSSNYPQDVNVQHLLLAGQVFYKVIREIPSGQELLLGPRTSLPLQDFSVGPHRKQISSSINHPPPTFRETPSILENEEHEDTQPRCSICDASFANIDVLDNHLIQAHGQPAAVHNCEVCLRAYSSRTLLLRHRALAHTDIRKYPCENCPKVFTDPSNLQRHIRAQHAGARSHACPECGKTFSTSSGLKQHTHIHSSVKPFQCKVCFKAYTQFSNLCRHKRMHVACRALVDCGKCGQSFNTYASLTKHKRFCDNATAASGLRGQLPQGLPQIPSLSNVMNTPNNSNPFSIMYRESALRLPYNFAHYPAAAFLPEFMNPFFNMQGARLALEQDFALSNAQLAKQQEGRMSVKSIDSSNSLDEPKKHKDLEFDSNKSDTTDRATPKSVFTKRSPPSAEEATSQHRPSPMMPSHVGFNFTAEALKRKSPYDYTLKLSQSDVQEPKSVSPALAKMSKNDGEEDKASEYSDVEDETTKGLDDQPLDLTMSRKPSDKESEAEADDRYYRNSIKSYSPPESPVERSKTPENDTTDVDVENVEPKREESPPQLVAPPLAFPMPVHPQHNNIIDAMYRPRFPSFHTTDSILNSSHTPYVPSPFNFLSPLLGTDGPDRQTSAYAKFAGTGKLRDRYACKFCGKVFPRSANLTRHLRTHTGEQPYKCKYCERSFSISSNLQRHVRNIHNKERPFRCPLCDRCFGQQTNLDRHLKKHEAEGGDSPSSADTERDDSYFDDIRSFMGKVTCSPGARSPPATSPHAPHPPHRPSLAIST

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity: iTF_00826051;
90% Identity: iTF_00666712;
80% Identity: -