Basic Information

Gene Symbol
-
Assembly
GCA_947172395.1
Location
OX359231.1:1482342-1495209[+]

Transcription Factor Domain

TF Family
zf-C2H2
Domain
zf-C2H2 domain
PFAM
PF00096
TF Group
Zinc-Coordinating Group
Description
The C2H2 zinc finger is the classical zinc finger domain. The two conserved cysteines and histidines co-ordinate a zinc ion. The following pattern describes the zinc finger. #-X-C-X(1-5)-C-X3-#-X5-#-X2-H-X(3-6)-[H/C] Where X can be any amino acid, and numbers in brackets indicate the number of residues. The positions marked # are those that are important for the stable fold of the zinc finger. The final position can be either his or cys. The C2H2 zinc finger is composed of two short beta strands followed by an alpha helix. The amino terminal part of the helix binds the major groove in DNA binding zinc fingers. The accepted consensus binding sequence for Sp1 is usually defined by the asymmetric hexanucleotide core GGGCGG but this sequence does not include, among others, the GAG (=CTC) repeat that constitutes a high-affinity site for Sp1 binding to the wt1 promoter [1].
Hmmscan Out
# of c-Evalue i-Evalue score bias hmm coord from hmm coord to ali coord from ali coord to env coord from env coord to acc
1 10 0.062 3.4 8.5 6.2 1 23 408 430 408 430 0.98
2 10 0.0058 0.32 11.7 0.6 2 23 438 459 437 459 0.96
3 10 3.9 2.1e+02 2.8 0.6 1 23 463 485 463 485 0.95
4 10 0.00021 0.011 16.3 2.7 1 23 490 513 490 513 0.98
5 10 0.00016 0.0085 16.7 2.6 1 23 517 540 517 540 0.96
6 10 0.0088 0.48 11.2 0.2 2 22 552 572 552 576 0.93
7 10 0.91 49 4.8 0.4 2 23 603 625 602 625 0.94
8 10 8.2e-05 0.0045 17.6 2.5 3 23 642 662 641 662 0.98
9 10 1.8e-05 0.00095 19.7 1.9 1 23 668 690 668 690 0.98
10 10 9.9e-06 0.00054 20.4 0.2 1 19 697 715 697 716 0.96

Sequence Information

Coding Sequence
ATGAAGTGCTGTGTATCTTGGTGTAGTAACACCAAAAGCAAGCTCAGCTCTGAAAGCGTTTCATATCACAAATTTCCTGTAGAAAACTTTCAACAACAAACCTGGATCGCAGCACTTGGCATTGATGACAGGCAGCTAACAGATGACTCCGTAGTCTGTTCCATTCACTTTATAGACGAATGCTTCTACAGCGGCGAGAGTGGGCTGAGAATTGTGCACAGAGGTGCTATGCCGTTTGTTCAGGTGTGCGTGGTGTGCCTGGACACAGAGCGGAGGGTGCATCCGTTGAGCAAGTACAACCTCGAGCAAGCTTACGAAACTATCACTGGACTTGAACTGCAAGGTCTAACGAACTTCACACCATGCATATGCTTTGAGTGTGCTCAGAGGTTGACACAGTGCAAACAGTTCAGAGACAAGAGTGCGAGGGGGCACGCTCTGCTGGTGGAGTTGATCAGGAAACATGAATTGCTAACTGTACAATATATAAAGACAATAAACCGTTCAGACAATTTTCTAACATCTAATCTAGTCGAGAAAGTGTTCCAACCAAACCATTGTGACTTAAACTTTATAGATAACAAAAAAGAGACCATAGAGATTGAATATGAAGACAGAGTGAATAAATCCACAATCAAAATAGAGAAAGACGATCACATATTGGTTTTTGATGATAAAACACAATATGAAAACTGTACAGATCTTGAAAAAAGGGATATTAAGGATGATGATACTAATGTAGACTTTTTAGATGATGTTTTCTCAAATAATGATGATGGTGATGAACTTTTGAATGATAATGCTAAAATTGATAATAATTATAGTGAAAAAGATGACATAAGTGACAGTGAAAAATCTATAGATCGAAATGAAAACGATAGTGACATAGAGCTAGTGCATTACAAAAAAGACAAACCAAAAACAAGTGACGCTAAAAAACTCAAAAGATCTAGAAAAATTAACTTAGCCTCATACAAGAACTGTAATAACAAAATAAGTAAAACTAATAAAAATAATTTAACCAAAAAAGTTAGTGTTGCCAAAACTAGAACTGGACCAGTTAAAAGTAAAGTTAAATTGGATAAAGTTAATACTAAAAAGTTAAATGCAAACAAACGTGACACGTGCTTAACTATTTTCAAAATGACTAAACTAAGTCTTGAAGAACAAATTGAAGACGTTAAGAAGCGACAAGAGTCTTCAAATTATAAGAATTCTAGTTTTCAATGCAATTTTTGCTACAGAGGTTTTATATGCAAGTCAACATTCACTAGACATATGGATAAACATTCTAAGGCAAACGGAGATGTGGAATGTCCGGTGTGCAAACAGCGTTACAAGACTCGGATAGCCTTCCTCAAACACAACCAGAGCCACACGACCAGATATAACTGCACACTGTGTGAATTCTTCTCTATGAACTCTGAATCTGCCAGGATGCACGAGCGCTGGCACAAGGGGACAAAGTATAAATGTCCGCACTGCGAGGAAGAATTCTCCAAATACACGACGTACATAACGCACCTGCGCGTGAAGCATCCGTCGGACTTTATCTGCGGTCACTGCGGCTACTCTTTCATCAGTCAGAAGGGCTTGGAGTACCACATCCACCGCACGCATCGTACGGAGAAAACGGAGGAGCCAGCGGGTCCGCAGTGCGAGGAGTGCAAGGTTCGATTCTCGTCGCTGGCGGCGTACGAGCAGCACTTGAAAGTGTCGCCCAAACATCACAAGCCTGAGATGCGTGAAAGGAACCAATCTCTACCGCGACGTATGTACAAGAAAGACAACGCGCCGCCCTACGTCACGTGCGAGCAGTGCGGTATAAAGCTGAACGACTTCACGATGTACATCTACCACTTCAAACGCGAACATCCCGGTGACGTCAGAGCACAACACGCGCCGCGACCGCGAGAGGTGCTCTGCGAACAGTGTGGGAGGAGCTTCCAGACCGCGTTCCACCTGAAGGAGCACATGACGAAGCACACAGGACAGAAGGACTACCAGTGCGACGTGTGCGAGAAGCGATTCCGCACCAAAGTGTACCTCGACAAGCACAAGGAGACGCACGCCGCCACCCGCCCGCTGTACTCCTGCCCCGTCTGCGGCAAGAGCTTCACCAGCCCGTCGAGTCGCAACCGACACGTATGGGTGAGTGTGAGCCTCGTATTAGTCATGCGATGCGCAACTGGATGA
Protein Sequence
MKCCVSWCSNTKSKLSSESVSYHKFPVENFQQQTWIAALGIDDRQLTDDSVVCSIHFIDECFYSGESGLRIVHRGAMPFVQVCVVCLDTERRVHPLSKYNLEQAYETITGLELQGLTNFTPCICFECAQRLTQCKQFRDKSARGHALLVELIRKHELLTVQYIKTINRSDNFLTSNLVEKVFQPNHCDLNFIDNKKETIEIEYEDRVNKSTIKIEKDDHILVFDDKTQYENCTDLEKRDIKDDDTNVDFLDDVFSNNDDGDELLNDNAKIDNNYSEKDDISDSEKSIDRNENDSDIELVHYKKDKPKTSDAKKLKRSRKINLASYKNCNNKISKTNKNNLTKKVSVAKTRTGPVKSKVKLDKVNTKKLNANKRDTCLTIFKMTKLSLEEQIEDVKKRQESSNYKNSSFQCNFCYRGFICKSTFTRHMDKHSKANGDVECPVCKQRYKTRIAFLKHNQSHTTRYNCTLCEFFSMNSESARMHERWHKGTKYKCPHCEEEFSKYTTYITHLRVKHPSDFICGHCGYSFISQKGLEYHIHRTHRTEKTEEPAGPQCEECKVRFSSLAAYEQHLKVSPKHHKPEMRERNQSLPRRMYKKDNAPPYVTCEQCGIKLNDFTMYIYHFKREHPGDVRAQHAPRPREVLCEQCGRSFQTAFHLKEHMTKHTGQKDYQCDVCEKRFRTKVYLDKHKETHAATRPLYSCPVCGKSFTSPSSRNRHVWVSVSLVLVMRCATG

Similar Transcription Factors

Sequence clustering based on sequence similarity using MMseqs2

100% Identity
iTF_00205243;
90% Identity
iTF_00205243;
80% Identity
iTF_00205243;